J C Hemphill

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, USA San Francisco Injury Center, San Francisco, CA, USA
    Physiol Meas 26:373-86. 2005
  2. ncbi request reprint The ICH score: a simple, reliable grading scale for intracerebral hemorrhage
    J C Hemphill
    Department of Neurology, University of California, San Francisco, USA
    Stroke 32:891-7. 2001
  3. ncbi request reprint Report from the Indian Third National Workshop on Critical Care Neurology
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, San Francisco, CA 94110, USA
    Neurocrit Care 3:282-3. 2005
  4. ncbi request reprint Brain tissue oxygen monitoring in intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, 94110, USA
    Neurocrit Care 3:260-70. 2005
  5. ncbi request reprint Hospital usage of early do-not-resuscitate orders and outcome after intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, Calif, USA
    Stroke 35:1130-4. 2004
  6. ncbi request reprint Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage
    J Kim
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:520-5. 2008
  7. ncbi request reprint The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injury
    Richard H Kallet
    Critical Care Division, Department of Anesthesia, University of California, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
    Respir Care 52:989-95. 2007
  8. pmc Do-not-resuscitate orders, unintended consequences, and the ripple effect
    J Claude Hemphill
    Department of Neurology, Room 4M62, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Crit Care 11:121. 2007
  9. ncbi request reprint Cumulative dose of hypertension predicts outcome in intracranial hemorrhage better than American Heart Association guidelines
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Acad Emerg Med 14:695-701. 2007
  10. ncbi request reprint International neurocritical care: report from the Costa Rica Neurointensive and Neuromonitoring Course
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Neurocrit Care 8:308-9. 2008

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, USA San Francisco Injury Center, San Francisco, CA, USA
    Physiol Meas 26:373-86. 2005
    ..High frequency data acquisition may be necessary for more precise evaluation of secondary brain injury in neurocritical care...
  2. ncbi request reprint The ICH score: a simple, reliable grading scale for intracerebral hemorrhage
    J C Hemphill
    Department of Neurology, University of California, San Francisco, USA
    Stroke 32:891-7. 2001
    ..Despite several existing outcome prediction models for ICH, there is no standard clinical grading scale for ICH analogous to those for traumatic brain injury, subarachnoid hemorrhage, or ischemic stroke...
  3. ncbi request reprint Report from the Indian Third National Workshop on Critical Care Neurology
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, San Francisco, CA 94110, USA
    Neurocrit Care 3:282-3. 2005
  4. ncbi request reprint Brain tissue oxygen monitoring in intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, 94110, USA
    Neurocrit Care 3:260-70. 2005
    ..We report complementary preliminary studies in a large animal model and in patients that demonstrate the feasibility of PbrO2 monitoring after ICH...
  5. ncbi request reprint Hospital usage of early do-not-resuscitate orders and outcome after intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, Calif, USA
    Stroke 35:1130-4. 2004
    ..Do-not-resuscitate (DNR) orders are commonly used after severe stroke. We hypothesized that there is significant variability in how these orders are applied after intracerebral hemorrhage and that this influences outcome...
  6. ncbi request reprint Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage
    J Kim
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:520-5. 2008
    ....
  7. ncbi request reprint The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injury
    Richard H Kallet
    Critical Care Division, Department of Anesthesia, University of California, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
    Respir Care 52:989-95. 2007
    ..We examined the relationship between f/VT, WOB, and respiratory system mechanics in patients with ARDS/ALI...
  8. pmc Do-not-resuscitate orders, unintended consequences, and the ripple effect
    J Claude Hemphill
    Department of Neurology, Room 4M62, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Crit Care 11:121. 2007
    ..As illustrated by the example of intracerebral hemorrhage, this may unexpectedly influence outcome even in patients without DNR orders in place...
  9. ncbi request reprint Cumulative dose of hypertension predicts outcome in intracranial hemorrhage better than American Heart Association guidelines
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Acad Emerg Med 14:695-701. 2007
    ..The American Heart Association recommends that blood pressure be maintained at a mean arterial pressure (MAP) less than 130 mm Hg to prevent secondary brain injury...
  10. ncbi request reprint International neurocritical care: report from the Costa Rica Neurointensive and Neuromonitoring Course
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Neurocrit Care 8:308-9. 2008
  11. doi request reprint Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials
    Hooman Kamel
    Department of Neurology, University of California, San Francisco, CA, USA
    Crit Care Med 39:554-9. 2011
    ..We therefore combined their findings in a meta-analysis...
  12. ncbi request reprint A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, CA 94110, USA
    Acad Emerg Med 12:1-6. 2005
    ..The authors hypothesized that a new method that accounts for the cumulative depth and duration of SBIs would provide a more informative measure that better correlates with outcome...
  13. ncbi request reprint Diagnosis of posttraumatic transverse sinus thrombosis with magnetic resonance imaging/magnetic resonance venography: report of two cases
    Alfredo Quinones-Hinojosa
    Department of Neurosurgery, San Francisco General Hospital, University of California, 94143 0112, USA
    J Trauma 56:201-4. 2004
  14. doi request reprint Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury
    Alexander C Flint
    Department of Neurology, Neurovascular and Neurocritical Care Service, University of California San Francisco, San Francisco General Hospital, San Francisco, California 94110, USA
    J Neurotrauma 25:503-12. 2008
    ..Severity of initial CT findings may predict the risk of contusion expansion following hemicraniectomy, thereby identifying a subgroup of patients who might benefit from therapies aimed at augmenting the coagulation system...
  15. pmc Clinical nihilism in neuroemergencies
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, University of California, San Francisco, CA 94110, USA
    Emerg Med Clin North Am 27:27-37, vii-viii. 2009
    ....
  16. pmc Prospective validation of the ICH Score for 12-month functional outcome
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, USA
    Neurology 73:1088-94. 2009
    ..The goals of this study were to assess whether the ICH Score accurately stratifies patients with regard to 12-month functional outcome and to further delineate the pace of recovery of patients during the first year post-ICH...
  17. ncbi request reprint Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
    ..Because large-vessel occlusion and stroke severity are likely correlated, it is unclear if largevessel occlusion independently predicts outcome or is simply a marker for stroke severity...
  18. ncbi request reprint Carbon dioxide reactivity and pressure autoregulation of brain tissue oxygen
    J C Hemphill
    Department of Neurology, University of California San Francisco, 94143-0112, USA
    Neurosurgery 48:377-83; discussion 383-4. 2001
    ..The relationship of PbrO2 with ET-CO2 and MAP appears to be similar to those historically established for CBF with ET-CO2 and MAP. This suggests that, under normal conditions, PbrO2 is strongly influenced by factors that regulate CBF...
  19. ncbi request reprint Continuous monitoring of the microcirculation in neurocritical care: an update on brain tissue oxygenation
    Jack C Rose
    Neurovascular Service, University of California, San Francisco, California 94110, USA
    Curr Opin Crit Care 12:97-102. 2006
    ..This article summarizes recent clinical and experimental studies of parenchymal brain tissue oxygen monitoring and considers future directions for its use in neurocritical care...
  20. doi request reprint Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, USA
    Crit Care Med 36:1917-24. 2008
    ..The objective of this study was to evaluate whether P(bt)O2 more closely reflects variables related to cerebral oxygen diffusion or reflects cerebral oxygen delivery and metabolism...
  21. ncbi request reprint External validation of the ICH score
    Jennifer L Clarke
    Department of Neurology, University of California, San Francisco, and San Francisco General Hospital, CA 94110, USA
    Neurocrit Care 1:53-60. 2004
    ..The purpose of this study was to determine whether the ICH score accurately risk-stratifies patients in an independent cohort...
  22. ncbi request reprint New approaches to physiological informatics in neurocritical care
    MARCO D SORANI
    Program in Biological and Medical Informatics, University of California, San Francisco, USA
    Neurocrit Care 7:45-52. 2007
    ..We propose that advances in monitoring must be accompanied by advances in methods of high-frequency, multivariate data analysis that integrate the multiple processes occurring in critically ill patients...
  23. ncbi request reprint Critical care of acute ischemic stroke
    R A Bernstein
    Department of Neurology, San Francisco General Hospital, 1001 Potrero Avenue, Room 4M62, San Francisco, CA 94110, USA
    Curr Neurol Neurosci Rep 1:587-92. 2001
    ..In addition, there is concern that some of these interventions may preserve life at the cost of quality of life. This article reviews the evidence behind these approaches to the critical care of ischemic stroke...
  24. doi request reprint Intracerebral hemorrhage
    Lucas Elijovich
    Department of Neurology, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Semin Neurol 28:657-67. 2008
    ..Ongoing clinical trials are investigating surgical evacuation of lobar hemorrhage, minimally invasive surgical hematoma evacuation, and aggressive blood pressure lowering...
  25. ncbi request reprint Advanced cerebral monitoring in neurocritical care
    Nobl Barazangi
    Department of Neurology, University of California, San Francisco and Neurocritical Care Program, San Francisco General Hospital, California 94110, USA
    Neurol India 56:405-14. 2008
    ....
  26. doi request reprint The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury
    Campbell Stewart
    Department of Surgery, San Francisco General Hospital, University of California, San Francisco, San Francisco, California 94110, USA
    Neurosurgery 63:1159-64; discussion 1164-5. 2008
    ..We also describe our clinical experience with the Licox PMO probe...
  27. ncbi request reprint Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine
    Seong K Lee
    San Francisco Injury Center, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
    Acad Emerg Med 9:969-76. 2002
    ....
  28. doi request reprint The role of lung function in brain tissue oxygenation following traumatic brain injury
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, California, USA
    J Neurosurg 108:59-65. 2008
    ..The purpose of this study was to investigate the influence of lung function on PbtO2 with an oxygen challenge (increase in fraction of inspired oxygen [FiO2] concentration to 1.0)...
  29. ncbi request reprint Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke
    Jack W Tsao
    Department of Neurology, San Francisco General Hospital, San Francisco, Calif, USA
    Arch Neurol 62:1126-9. 2005
    ..Consequently, there is less published information on thrombolytic therapy for posterior circulation stroke...
  30. pmc Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review
    B B Thompson
    Department of Neurology, Brown University, Providence, RI, USA
    Neurology 75:1333-42. 2010
    ..We performed a systematic review and meta-analysis to address the hypothesis that pre-ICH APT use is associated with mortality and poor functional outcome following ICH...
  31. ncbi request reprint Transcranial Doppler ultrasonography in the neurologic intensive care unit
    V Singh
    Neurovascular Service, Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, California 94143, USA
    Neurol India 49:S81-9. 2001
    ..TCD is likely to play a larger role in evaluation of the patient in the future because of its safety, portability and ability to define moment-to-moment changes in cerebral blood flow velocities and cerebral blood flow...
  32. ncbi request reprint Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA 94110, USA
    AJNR Am J Neuroradiol 26:1095-100. 2005
    ..The purpose of this study was to determine if there is a relationship between CT perfusion (CTP) imaging parameters and P(br)O(2)...
  33. pmc Prevalence and prognosis of coexistent asymptomatic intracranial stenosis
    Fadi Nahab
    Stroke 39:1039-41. 2008
    ..There are limited data on the prevalence and prognosis of asymptomatic intracranial stenosis (AIS)...
  34. ncbi request reprint Stroke thrombolysis in the elderly: risk or benefit?
    J Claude Hemphill
    Neurology 65:1690-1. 2005
  35. ncbi request reprint Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation
    Geoffrey T Manley
    School of Medicine, University of California San Francisco, San Francisco Injury Center, Department of Neurological Surgery, USA
    Adv Exp Med Biol 530:311-7. 2003
    ..To investigate the effects of small-volume resuscitation with a hemoglobin based oxygen carrier on brain tissue oxygen tension (PbrO2) in hemorrhaged swine...
  36. ncbi request reprint Program requirements for fellowship training in neurological intensive care: United Council for Neurologic Subspecialties guidelines
    Stephan A Mayer
    United Council for Neuroloic Subspecialties, St Paul, MN 55116, USA
    Neurocrit Care 5:166-71. 2006
  37. ncbi request reprint Treating warfarin-related intracerebral hemorrhage: is fresh frozen plasma enough?
    J Claude Hemphill
    Stroke 37:6-7. 2006
  38. ncbi request reprint The need for a registry renaissance in neurocritical care
    J Claude Hemphill
    Crit Care Med 35:2208-9. 2007
  39. ncbi request reprint Core curriculum and competencies for advanced training in neurological intensive care: United Council for Neurologic Subspecialties guidelines
    Stephan A Mayer
    United Council for Neurologic Subspecialties, St Paul, MN 55116, USA
    Neurocrit Care 5:159-65. 2006