Research Topics
| Alan W HemmingSummaryAffiliation: University of Florida Country: USA Publications
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Publications
Combined resection of the liver and inferior vena cava for hepatic malignancyAlan W Hemming
Department of Surgery, Center for Hepatobiliary Diseases, PO Box 100286, University of Florida, Gainesville, FL 32610 0286, USA
Ann Surg 239:712-9; discussion 719-21. 2004..The morbidity and mortality along with preliminary survival data are assessed in order to determine the utility of this aggressive approach to otherwise unresectable tumors...
Role for extending hepatic resection using an aggressive approach to liver surgeryAlan W Hemming
Division of Transplantation and Hepatobiliary Surgery, University of Florida, Gainesville, FL 32610, USA
J Am Coll Surg 206:870-5; discussion 875-8. 2008..This study assesses liver resection in patients who were unresectable with standard liver resection but were potentially resectable using an aggressive approach to liver surgery...
Preoperative portal vein embolization for extended hepatectomyAlan W Hemming
Department of Surgery, Center for Hepatobiliary Disease, University of Florida, Gainesville, FL 32610, USA
Ann Surg 237:686-91; discussion 691-3. 2003..To examine the authors' experience with preoperative ipsilateral portal vein embolization (PVE) and assess its role in extended hepatectomy...
Portal vein resection for hilar cholangiocarcinomaAlan W Hemming
University of Florida Center for Hepatobiliary Disease, College of Medicine, Department of Surgery, Gainesville, Florida 32610-0286, USA
Am Surg 72:599-604; discussion 604-5. 2006..Only negative margin status was associated with improved survival by multivariate analysis. Portal vein resection for hilar cholangiocarcinoma is safe and allows a chance for long-term survival in otherwise unresectable patients...
Is early recurrence of hepatitis C associated with biliary anastomotic stricture after liver transplantation?Shiro Fujita
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610 0286, USA
Transplantation 84:1631-5. 2007..The aim of the current study is to determine if recurrence of hepatitis C affects biliary complications after LT, with special reference to late biliary anastomotic strictures (LBAS)...
Combined resection of the liver and pancreas for malignancyAlan W Hemming
Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California at San Diego, San Diego, CA 92103 8401, USA
J Am Coll Surg 210:808-14, 814-6. 2010..The purpose of this study was to assess our results with combined resection of the liver and pancreas...
Liver transplantation from donation after cardiac death: a single center experienceShiro Fujita
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
Transplantation 84:46-9. 2007..Although early reports of LT from DCD donors provided evidence for acceptable outcomes, long-term graft and patient survival rates from these procedures have been reviewed only recently...
Hepatic vein reconstruction for resection of hepatic tumorsAlan W Hemming
Department of Surgery, Center for Hepatobiliary Disease, University of Florida, Gainesville 32610, USA
Ann Surg 235:850-8. 2002..Recent advances in liver surgery gleaned from split and live donor liver transplantation that necessitate hepatic vein reconstruction can be applied to hepatic resection in some cases...
Surgical management of hilar cholangiocarcinomaAlan W Hemming
Department of Surgery, Center for Hepatobiliary Diseases, University of Florida, Gainesville, Florida 32610 0286, USA
Ann Surg 241:693-9; discussion 699-702. 2005..To assess the surgical management of hilar cholangiocarcinoma over a time period when liver resection was considered standard management...
Consensus and controversy in the management of hepatocellular carcinomaRobin D Kim
Division of Transplantation and Hepatobiliary and Pancreatic Surgery, Department of Surgery, University of Florida School of Medicine, Gainesville, FL 32610-0286, USA
J Am Coll Surg 205:108-23. 2007
Contemporary results with ampullectomy for 29 "benign" neoplasms of the ampullaStephen R Grobmyer
Division of Surgical Oncology and Endocrine Surgery, University of Florida, Gainesville, FL 32610, USA
J Am Coll Surg 206:466-71. 2008..Ampullectomy may be an appropriate oncologic procedure in selected patients. Sparse data exist on procedure-related complications and the relationship between histologic analysis and outcomes...
One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infectionRoberto J Firpi
Division of Gastroenterology, Hepatology, and Nutrition Section of Hepatobiliary Diseases, University of Florida, Gainesville, FL 32610 0214, USA
Liver Transpl 10:1240-7. 2004..A liver biopsy performed at 1 year posttransplant can help identify those patients more likely to develop progressive disease and may allow better targeting of antiviral therapy...
Impact of implementation of the MELD scoring system on the prevalence and incidence of chronic renal disease following liver transplantationVictor I Machicao
Division of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, FL 32610-0214, USA
Liver Transpl 12:754-61. 2006..In conclusion, the implementation of the MELD allocation system is not associated with increased mortality or occurrence of CRD-3 or CRD-4 in the first 2 years after LT...
Adult post-transplant lymphoproliferative disease in the liver graft in patients with recurrent hepatitis CRobin D Kim
Section of Transplantation, Department of Surgery, University of Utah School of Medicine, 30 North 1900 East, Salt Lake City, UT 84103, USA
Eur J Gastroenterol Hepatol 23:559-65. 2011..The aim of this study is to clarify the association between hepatitis C virus (HCV) infection and post-transplant lymphoproliferative disease (PTLD) in the liver allograft...
Hepatocellular carcinoma in a 10-month-old biliary atresia childTaku Iida
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610 0286, USA
Pediatr Transplant 13:1048-9. 2009..The occurrence of HCC in a child under one yr old is extremely rare, and only three cases are reported so far including our case...
Portal vein resection in management of hilar cholangiocarcinomaAlan W Hemming
Department of Surgery, Center for Hepatobiliary Disease and Abdominal Transplantation, University of California San Diego, San Diego, CA 92013 8401, USA
J Am Coll Surg 212:604-13; discussion 613-6. 2011..The purpose of this report is to assess the role of portal vein resection and reconstruction in the surgical management of hilar cholangiocarcinoma...
Ex vivo extended left hepatectomy with caval preservation, temporary portacaval shunt, and reconstruction of the right hepatic vein outflow using a reversed portal vein bifurcation graftAlan W Hemming
Department of Surgery, University of Florida, College of Medicine, Gainesville, FL 32610, USA
J Hepatobiliary Pancreat Surg 13:525-9. 2006..Ex vivo resection allowed reconstruction of right hepatic vein branches, using the patient's reversed portal vein bifurcation as a graft to provide venous outflow...
Major hepatectomy induces phenotypic changes in circulating dendritic cells and monocytesPhilip A Efron
Department of Surgery, University of Florida College of Medicine, Shands Hospital, Box 100286, Gainesville, FL 32610 0286, USA
J Clin Immunol 29:568-81. 2009..Patients undergoing major hepatectomy are at increased risk for post-operative morbidity and mortality, and changes in the phenotype of effector cells may predispose these patients to infectious sequelae...
The changing causes of graft loss and death after kidney transplantationRichard J Howard
Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610-0286, USA
Transplantation 73:1923-8. 2002..By better addressing the main causes of death, cardiac disease, and stroke with better prevention, graft loss due to death with a functioning graft will be reduced...
Hepatocellular carcinoma: resection or transplantationRobin D Kim
Division of Transplantation and Hepatobiliary and Pancreatic Surgery, Department of Surgery, University of Florida School of Medicine, 1600 S W Archer Rd, Room 6142, PO Box 100286, Gainesville, FL 32610 0286, USA
J Gastrointest Surg 13:1023-5. 2009..The exact role of liver transplantation versus resection remains to be determined. The following short review attempts to present the evidence for the respective roles of liver transplantation versus liver resection in early stage HCC...
Duplicate gallbladder arising from the left hepatic duct: report of a caseRobin D Kim
Division of Transplantation and Hepatobiliary and Pancreatic Surgery, Department of Surgery, University of Florida School of Medicine, 1600 S W Archer Road, Room 6142, P O Box 100286, Gainesville, FL, 32610 0286, USA
Surg Today 39:536-9. 2009..We discuss the classification of anomalous gallbladder anatomy and review previous cases, to propose a modification of the common classification scheme...
Left trisegmentectomy with reconstruction of segment 6 hepatic venous outflow using cryopreserved vein graftAlan W Hemming
Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610 0286, USA
J Gastrointest Surg 9:353-6. 2005..We describe a left trisegmentectomy with bile duct resection/reconstruction during which the segment 6 hepatic vein was reconstructed into the inferior vena cava using a cryopreserved vein graft...
Liver transplantation in children with sickle-cell diseaseKristin L Mekeel
Division of Transplantation, Department of Surgery, University of Florida, Gainesville, FL 32610, USA
Liver Transpl 13:505-8. 2007..Careful attention must be paid to HbS fraction and hemoglobin level to prevent sickling and vascular thrombosis. Unfortunately, liver transplant cannot alter the natural course of the disease...
Presentation and management of gastrointestinal stromal tumors of the duodenumRobert D Winfield
Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, The College of Medicine, University of Florida, Gainesville, Florida, USA
Am Surg 72:719-22; discussion 722-3. 2006..Duodenal GIST are relatively rare tumors that present most commonly with gastrointestinal bleeding. Duodenal GIST are associated with neurofibromatosis. Many duodenal GIST require pancreaticoduodenectomy for complete removal...
Combined en bloc liver pancreas transplantation for children with CFKristin L Mekeel
Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610, USA
Liver Transpl 13:406-9. 2007..0%, P = 0.04, and 100% vs. 0%, P = 0.01, respectively). In conclusion, patients with CF and end-stage liver disease requiring liver transplantation may benefit from combined liver-pancreas transplantation...
Case of emphysematous pyelonephritis in a renal allograftShiro Fujita
Division of Transplantation, Department of Surgery, University of Flordia College of Medicine, Gainesville, FL 32610 0286, USA
Clin Transplant 19:559-62. 2005..Her hospital course was complicated by a urinary leak; she was discharged to home on day 21. This is the 12th reported case of emphysematous pyelonephritis occurred in a renal transplant recipient...
Treatment outcomes and prognostic factors of intrahepatic cholangiocarcinomaRenumathy Dhanasekaran
Department of Medicine, University of Florida, Gainesville, FL, USA
Oncol Rep 29:1259-67. 2013..The overriding factors influencing outcome were stage and the presence of microvascular invasion on pathology...
Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomySteven N Hochwald
Division of Surgical Oncology and Endocrine Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
J Surg Oncol 101:351-5. 2010..A Braun enteroenterostomy has been shown to decrease bile reflux following gastric resection. We hypothesize that addition of Braun enteroenterostomy during PD would reduce the sequelae of DGE...
Combined hepatic resection and radiofrequency ablation for multiple hepatic adenomasShiro Fujita
Department of Surgery, College of Medicine, University of Florida, Gainesville, Florida 32610 0286, USA
J Gastroenterol Hepatol 21:1351-4. 2006..We show three cases without recurrent lesions detected in follow-up examination. Two of the patients have subsequently gone on to carry pregnancies successfully to term...
A pilot prospective randomized trial of postoperative epoetin alfa in patients undergoing major operation for upper gastrointestinal malignancyStephen R Grobmyer
Departments of Surgery, University of Florida, Gainesville, FL, USA
Am J Clin Oncol 32:570-3. 2009..Hypothesis: Postoperative epoetin alfa (40,000 units subcutaneous on postoperative days 1 and 7) is associated with improved hematologic parameters in patients undergoing major abdominal surgery for malignancy...
Liver transplantation in very small infantsKristin L Mekeel
Division of Transplantation and Hepatobiliary Surgery, University of Florida, Gainesville, FL 32410, USA
Pediatr Transplant 11:66-72. 2007..However, over half of all children needing LT are <1 year old. Improving outcomes in very small children is a major goal of liver transplantation...
Combined resection of the liver and the inferior vena cava for hydatid diseaseKristin L Mekeel
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
J Gastrointest Surg 11:1741-3. 2007..We present a case of hydatid disease with complete caval obstruction and resultant portal hypertension that required combined liver resection and inferior vena cava replacement...
Clostridial infection in a liver transplant recipientDiego R Solis
Department of Surgery, Division of Transplantation, University of Florida College of Medicine, Gainesville, FL, USA
Clin Transplant 18:726-8. 2004..Clostridium perfringens infection in a liver transplant recipient is a rare complication. We report a case of a liver allograft gas gangrene. The case illustrates the fulminant and rapidly devastating course of this complication...
Endovascular stent graft repair of abdominal aortic aneurysms after liver transplantationKristin L Mekeel
Division of Transplantation, Department of Surgery, University of Florida, Gainesville, FL 32610, USA
Liver Transpl 11:993-7. 2005..This article describes our experience with AAAs in orthotopic liver transplant recipients treated successfully by endovascular stent graft repair...
Surgical management of gallbladder carcinoma: a reviewKristin L Mekeel
Department of Surgery, Mayo Clinic Hospital, Phoenix, AZ 85054, USA
J Gastrointest Surg 11:1188-93. 2007..This article reviews the current approach to the surgical management of gallbladder cancer and discusses the rationale for an aggressive approach to this disease...
Elevation of serum IgG4 in Western patients with autoimmune sclerosing pancreatocholangitis: a word of cautionSteven N Hochwald
Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, 100286, Gainesville, Florida, USA
Ann Surg Oncol 15:1147-54. 2008..Serum immunoglobin (Ig) G4 values seem to be helpful in distinguishing autoimmune pancreatocholangitis from pancreatic malignancy in the Japanese population; however, its significance in the Western population has not been well studied...
The effects of renal transplantation on peripheral blood dendritic cellsKarl L Womer
Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USA
Clin Transplant 19:659-67. 2005..Furthermore, PBDC monitoring may represent a novel strategy to predict important outcomes such as acute rejection, long-term graft loss and infectious complications...
Listeria monocytogenes following orthotopic liver transplantation: central nervous system involvement and review of the literatureShugo Mizuno
Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, PO Box 100286, Gainesville, FL 32610 0286, United States
World J Gastroenterol 13:4391-3. 2007..There were four cases of listeria meningitis, and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis...
Combined liver and pancreas resection with biochemotherapy for metastatic ocular melanomaRamsey Camp
Shands Cancer Center, University of Florida, Gainesville, FL, USA
J Hepatobiliary Pancreat Surg 9:519-21. 2002..Data from well-designed, innovative clinical trials of cytoreductive surgery and biochemotherapy are required to determine the effectiveness of this multidisciplinary approach...
Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis CManal F Abdelmalek
Department of Medicine, Section of Hepatobiliary Diseases University of Florida, Gainesville, FL 32610 0214, USA
Liver Transpl 10:199-207. 2004..05). In conclusion, loss of HCV after treatment of recurrent chronic hepatitis C with interferon and ribavirin is durable, and the durability of the SVR is associated with improvement in hepatic inflammation and regression of fibrosis...
Obesity does not portend a bad outcome for kidney transplant recipientsRichard J Howard
Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610-0286, USA
Transplantation 73:53-5. 2002..Group 3 patients, however, did have a higher incidence of steroid-induced posttransplantation diabetes mellitus than the other two groups (P<0.01). CONCLUSION: Obese transplant recipients have similar outcomes to nonobese patients...
Surgical management trends for cholangiocarcinoma in the USA 1998-2009Jamie E Anderson
Department of Surgery, University of California, San Diego, San Diego, CA 92103 8401, USA
J Gastrointest Surg 16:2225-32. 2012..Surgical advancements have improved outcomes for cholangiocarcinoma (CCA) patients, but this expertise is not uniformly available. This research examines CCA surgical treatment patterns...
Fulminant hepatic failure: when to transplantAjai Khanna
Abdominal Transplant and Hepatobiliary Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 West Arbor Drive, San Diego, CA 92103 8401, USA
Surg Clin North Am 90:877-89. 2010..With appropriate immunosuppression and close follow-up most patients can lead near normal lives following liver transplantation...
Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioningTadashi Matsumoto
Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA, and Department of Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan
Surgery 140:793-802. 2006..Ischemic preconditioning has been shown to protect the liver from ischemia/reperfusion injury. We hypothesized that IL-6 directly modulates the protective effects of ischemic preconditioning...
Retroperitoneal soft tissue sarcomaWilliam M Mendenhall
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL 32610, USA
Cancer 104:669-75. 2005..Most patients experienced recurrent disease after surgery, and the most common site of failure was local. Adjuvant RT reduced the risk of local recurrence, but its impact on survival was questionable...
Hepatic mucormycosis in a renal transplant recipientKristin L Mekeel
Transplantation 79:1636. 2005
Outcomes of liver transplantation in 490 patients with hepatocellular carcinoma: validation of a uniform staging after surgical treatmentJean Nicolas Vauthey
Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
J Am Coll Surg 204:1016-27; discussion 1027-8. 2007....
Expanded efficacy and indication of extracorporeal membrane oxygenation for preoperative pulmonary bleeding on pediatric cadaveric orthotopic liver transplantationShiro Fujita
Transplantation 79:1637. 2005
Recurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomesShimul A Shah
Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Canada
Surgery 141:330-9. 2007..The purpose of this study was to identify risk factors for the recurrence of HCC and to examine long-term outcomes after resection...
Liver-occupying focal nodular hyperplasia and adenomatosis associated with intrahepatic portal vein agenesis requiring orthotopic liver transplantationShiro Fujita
Transplantation 81:490-2. 2006
Heading in the right direction: improved outcome of surgery for advanced colorectal liver metastasesAlan W Hemming
Ann Surg Oncol 15:7-8. 2008
Localized intraocular posttransplant lymphoproliferative disorder after pediatric liver transplantationShiro Fujita
Transplantation 81:493-5. 2006
Psychosocial support after simultaneous pancreas and kidney transplantationShiro Fujita
Transpl Int 18:755-6. 2005
