Ricki M Helm

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi request reprint Food biotechnology: is this good or bad? Implications to allergic diseases
    Ricki M Helm
    Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202 3591, USA
    Ann Allergy Asthma Immunol 90:90-8. 2003
  2. ncbi request reprint Sensitization and allergic response and intervention therapy in animal models
    Ricki M Helm
    University of Arkansas for Medical Sciences ACHRI ACNC, Department of Microbiology Immunology, Little Rock, AR 72202 3591, USA
    J AOAC Int 87:1441-7. 2004
  3. ncbi request reprint Animal models of food allergy
    Ricki M Helm
    ACHRI UAMS, Department of Pediatrics, Little Rock, Arkansas 72202, USA
    Curr Opin Allergy Clin Immunol 2:541-6. 2002
  4. pmc Nonmurine animal models of food allergy
    Ricki M Helm
    Department of Pediatrics, Division of Allergy Immunology, University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas, USA
    Environ Health Perspect 111:239-44. 2003
  5. ncbi request reprint Diet regulates the development of gut-associated lymphoid tissue in neonatal piglets
    Ricki M Helm
    Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    Neonatology 91:248-55. 2007
  6. ncbi request reprint Cockroach and other inhalant insect allergens
    Ricki M Helm
    University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Clin Allergy Immunol 18:271-96. 2004
  7. ncbi request reprint Intralesional immunotherapy of warts with mumps, Candida, and Trichophyton skin test antigens: a single-blinded, randomized, and controlled trial
    Thomas D Horn
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Arch Dermatol 141:589-94. 2005
  8. ncbi request reprint Biotechnology and food allergy
    Ricki M Helm
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, 1120 Marshall Street, Little Rock, AR 72202 3591, USA
    Curr Allergy Asthma Rep 2:55-62. 2002
  9. ncbi request reprint Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulation
    Pat Rabjohn
    Department of Biochemistry and Molecular Biology, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Int Arch Allergy Immunol 128:15-23. 2002
  10. ncbi request reprint Diet and the development of atopic disease
    Ricki M Helm
    Department of Microbiology Immunology, Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Curr Opin Allergy Clin Immunol 4:125-9. 2004

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Food biotechnology: is this good or bad? Implications to allergic diseases
    Ricki M Helm
    Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202 3591, USA
    Ann Allergy Asthma Immunol 90:90-8. 2003
    ..With respect to safety, foods developed through biotechnology techniques represent one of the most extensively reviewed agricultural advancements in history...
  2. ncbi request reprint Sensitization and allergic response and intervention therapy in animal models
    Ricki M Helm
    University of Arkansas for Medical Sciences ACHRI ACNC, Department of Microbiology Immunology, Little Rock, AR 72202 3591, USA
    J AOAC Int 87:1441-7. 2004
    ..In summary, murine and swine animal models are being used to address immunotherapeutic avenues and investigation into the mechanisms of food-allergic sensitization...
  3. ncbi request reprint Animal models of food allergy
    Ricki M Helm
    ACHRI UAMS, Department of Pediatrics, Little Rock, Arkansas 72202, USA
    Curr Opin Allergy Clin Immunol 2:541-6. 2002
    ..The focus of this review will be on recent animal models of food allergy. Animal models are being used to investigate underlying mechanisms of IgE-mediated disease and for prophylactic/intervention therapies to treat allergic disease...
  4. pmc Nonmurine animal models of food allergy
    Ricki M Helm
    Department of Pediatrics, Division of Allergy Immunology, University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas, USA
    Environ Health Perspect 111:239-44. 2003
    ....
  5. ncbi request reprint Diet regulates the development of gut-associated lymphoid tissue in neonatal piglets
    Ricki M Helm
    Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    Neonatology 91:248-55. 2007
    ..Furthermore, studies on dietary effects on the development of the neonatal immune system, especially gut-associated lymphoid tissue (GALT), are lacking...
  6. ncbi request reprint Cockroach and other inhalant insect allergens
    Ricki M Helm
    University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Clin Allergy Immunol 18:271-96. 2004
  7. ncbi request reprint Intralesional immunotherapy of warts with mumps, Candida, and Trichophyton skin test antigens: a single-blinded, randomized, and controlled trial
    Thomas D Horn
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Arch Dermatol 141:589-94. 2005
    ..Other treatment options include immunotherapy. Intralesional immunotherapy using mumps, Candida, or Trichophyton skin test antigens has proved efficacy in the treatment of warts...
  8. ncbi request reprint Biotechnology and food allergy
    Ricki M Helm
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, 1120 Marshall Street, Little Rock, AR 72202 3591, USA
    Curr Allergy Asthma Rep 2:55-62. 2002
    ....
  9. ncbi request reprint Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulation
    Pat Rabjohn
    Department of Biochemistry and Molecular Biology, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Int Arch Allergy Immunol 128:15-23. 2002
    ..Mutational analysis of the Ara h 3 IgE-binding epitopes with synthetic peptides revealed that single amino acid changes at critical residues could diminish IgE binding...
  10. ncbi request reprint Diet and the development of atopic disease
    Ricki M Helm
    Department of Microbiology Immunology, Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Curr Opin Allergy Clin Immunol 4:125-9. 2004
    ..A search of the literature was carried out covering the following topics: diet and nutrition combined with immediate hypersensitivity, atopy, atopic disease, atopic dermatitis, and food allergy...
  11. ncbi request reprint Food allergy animal models: an overview
    Ricki M Helm
    Allergy and Immunology, University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, Little Rock 72202, USA
    Ann N Y Acad Sci 964:139-50. 2002
    ....
  12. ncbi request reprint Comparison of physiological and in vitro porcine gastric fluid digestion
    Randall A Kopper
    Department of Chemistry, Hendrix College, Conway, Ark, USA
    Int Arch Allergy Immunol 141:217-22. 2006
    ..In vitro digestion with porcine gastric fluid was compared with actual physiological digestion of peanut allergens in the porcine digestive tract in vivo...
  13. ncbi request reprint Peanut protein allergens: the effect of roasting on solubility and allergenicity
    Randall A Kopper
    Chemistry Department, Hendrix College, Conway, Ark 72202, USA
    Int Arch Allergy Immunol 136:16-22. 2005
    ..The effects of various treatments on the re-solubilization and subsequent allergenicity of this insoluble peanut protein material are presented here...
  14. ncbi request reprint Soy immunotherapy for peanut-allergic mice: modulation of the peanut-allergic response
    Laurent Pons
    Department of Pediatrics, Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 114:915-21. 2004
    ..So far, peanut-specific IT has been unsuccessful because of the side effects of therapy. Soybean seed storage proteins share significant homology with the respective peanut allergens...
  15. ncbi request reprint Peanut protein allergens: gastric digestion is carried out exclusively by pepsin
    Randall A Kopper
    Chemistry Department, Hendrix College, Conway, Arkansas, USA
    J Allergy Clin Immunol 114:614-8. 2004
    ..One estimate of the allergenic potential of a possible protein allergen is its stability under simulated gastric conditions...
  16. ncbi request reprint A neonatal swine model for peanut allergy
    Ricki M Helm
    Division of Allergy Immunology, Department of Pediatrics, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock 72201, USA
    J Allergy Clin Immunol 109:136-42. 2002
    ..As yet, no animal model has been developed that will completely mimic the physical, immunologic, and histologic features of food allergy...
  17. pmc Assessment of protein allergenicity on the basis of immune reactivity: animal models
    Ian Kimber
    Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, United Kingdom
    Environ Health Perspect 111:1125-30. 2003
    ..Progress made in the design and evaluation of models in the rat, the mouse, the dog and in swine is reviewed and discussed...
  18. pmc Genetic modification removes an immunodominant allergen from soybean
    Eliot M Herman
    Plant Genetics Research Unit, United States Department of Agriculture Agricultural Research Service, Donald Danforth Plant Science Center, 975 North Warson Street, St Louis, Missouri 63132, USA
    Plant Physiol 132:36-43. 2003
    ..These data provide evidence for substantial equivalence of composition of transgenic and non-transgenic seed eliminating one of the dominant allergens of soybean seeds...
  19. ncbi request reprint Workshop overview: approaches to the assessment of the allergenic potential of food from genetically modified crops
    Gregory S Ladics
    The DuPont Co, Haskell Laboratory, Newark, Delaware 19714, USA
    Toxicol Sci 73:8-16. 2003
    ..However, further efforts are needed to evaluate and validate the sensitivity, specificity, and reproducibility of many of these assays for determining the allergenicity potential of GM foods...
  20. ncbi request reprint Monitoring peanut allergen in food products by measuring Ara h 1
    Anna Pomes
    INDOOR Biotechnologies, Inc, Charlottesville, VA 22903, USA
    J Allergy Clin Immunol 111:640-5. 2003
    ..Peanut allergy is an important health problem in the United States, affecting approximately 0.6% of children. Inadvertent exposure to peanut is a risk factor for life-threatening food-induced anaphylaxis...
  21. ncbi request reprint IgE reactivity of tandem repeats derived from cockroach allergen, Bla g 1
    Anna Pomes
    Asthma and Allergic Diseases Center, Department of Medicine, University of Virginia, Charlottesville, VA, USA
    Eur J Biochem 269:3086-92. 2002
    ..The rBla g 1 is suitable for structural studies and a candidate for clinical use in diagnosis of cockroach allergy and development of new forms of immunotherapy...