HELEN HELLMICH

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. pmc Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS ONE 8:e53230. 2013
  2. pmc The inflammatory and normal transcriptome of mouse bladder detrusor and mucosa
    Marcia R Saban
    Department of Physiology, The University Oklahoma Health Sciences Center, Oklahoma City, USA
    BMC Physiol 6:1. 2006
  3. pmc Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins
    Marcia R Saban
    Department of Physiology, The University Oklahoma Health Sciences Center, Oklahoma City, USA
    BMC Cancer 7:204. 2007
  4. ncbi request reprint Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, USA
    Neurosci Lett 355:221-5. 2004
  5. ncbi request reprint Traumatic brain injury and hemorrhagic hypotension suppress neuroprotective gene expression in injured hippocampal neurons
    Helen Lee Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA
    Anesthesiology 102:806-14. 2005
  6. ncbi request reprint Dose-dependent neuronal injury after traumatic brain injury
    Helen Lee Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, USA
    Brain Res 1044:144-54. 2005
  7. pmc Injured Fluoro-Jade-positive hippocampal neurons contain high levels of zinc after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 0830, USA
    Brain Res 1127:119-26. 2007
  8. pmc Chelation of neurotoxic zinc levels does not improve neurobehavioral outcome after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, United States
    Neurosci Lett 440:155-9. 2008
  9. ncbi request reprint Characterization of the neurotrophic response to acute pancreatitis
    Hiroki Toma
    Enteric Neuromuscular Disorders and Pain Laboratory, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Pancreas 25:31-8. 2002

Research Grants

  1. In Vivo Gene Silencing with siRNA After Brain Trauma
    HELEN HELLMICH; Fiscal Year: 2006
  2. In Vivo RNAi of Injury Signals After Brain Injury
    HELEN HELLMICH; Fiscal Year: 2007
  3. In Vivo RNAi of Injury Signals After Brain Injury
    Helen L Hellmich; Fiscal Year: 2010

Collaborators

Detail Information

Publications9

  1. pmc Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS ONE 8:e53230. 2013
    ....
  2. pmc The inflammatory and normal transcriptome of mouse bladder detrusor and mucosa
    Marcia R Saban
    Department of Physiology, The University Oklahoma Health Sciences Center, Oklahoma City, USA
    BMC Physiol 6:1. 2006
    ..Here, we used suppression subtractive hybridizations (SSH) to determine bladder tissue- and disease-specific genes and transcriptional regulatory elements (TRE)s. Unique TREs and genes were assembled into putative networks...
  3. pmc Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins
    Marcia R Saban
    Department of Physiology, The University Oklahoma Health Sciences Center, Oklahoma City, USA
    BMC Cancer 7:204. 2007
    ..The objective of this study was to determine differentially expressed genes in the mouse bladder following repeated intravesical BCG therapy...
  4. ncbi request reprint Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, USA
    Neurosci Lett 355:221-5. 2004
    ..Zinc chelation induced the expression of several neuroprotective genes; neuroprotective gene expression correlated with substantially decreased numbers of TUNEL-positive cells...
  5. ncbi request reprint Traumatic brain injury and hemorrhagic hypotension suppress neuroprotective gene expression in injured hippocampal neurons
    Helen Lee Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA
    Anesthesiology 102:806-14. 2005
    ....
  6. ncbi request reprint Dose-dependent neuronal injury after traumatic brain injury
    Helen Lee Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, USA
    Brain Res 1044:144-54. 2005
    ....
  7. pmc Injured Fluoro-Jade-positive hippocampal neurons contain high levels of zinc after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 0830, USA
    Brain Res 1127:119-26. 2007
    ..Our data suggest that therapeutic interventions aimed at reducing neurotoxic zinc levels after TBI may reduce hippocampal neuronal injury...
  8. pmc Chelation of neurotoxic zinc levels does not improve neurobehavioral outcome after traumatic brain injury
    Helen L Hellmich
    Department of Anesthesiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0830, United States
    Neurosci Lett 440:155-9. 2008
    ....
  9. ncbi request reprint Characterization of the neurotrophic response to acute pancreatitis
    Hiroki Toma
    Enteric Neuromuscular Disorders and Pain Laboratory, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Pancreas 25:31-8. 2002
    ..Interesting preliminary data on changes in the neurotrophin system in various digestive diseases have recently begun to emerge...

Research Grants6

  1. In Vivo Gene Silencing with siRNA After Brain Trauma
    HELEN HELLMICH; Fiscal Year: 2006
    ....
  2. In Vivo RNAi of Injury Signals After Brain Injury
    HELEN HELLMICH; Fiscal Year: 2007
    ..In turn, this may open up avenues for therapeutic manipulation of deleterious gene expression in human patients. ..
  3. In Vivo RNAi of Injury Signals After Brain Injury
    Helen L Hellmich; Fiscal Year: 2010
    ..In turn, this may open up avenues for therapeutic manipulation of deleterious gene expression in human patients. ..