S L Hefle

Summary

Affiliation: University of Nebraska
Country: USA

Publications

  1. ncbi request reprint Development of a sandwich enzyme-linked immunosorbent assay for the detection of egg residues in processed foodst
    S L Hefle
    University of Nebraska Lincoln, Department of Food Science and Technology, 68583 0919, USA
    J Food Prot 64:1812-6. 2001
  2. ncbi request reprint How much food is too much? Threshold doses for allergenic foods
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, 351 Food Industry Complex, Lincoln, NE 68583 0919, USA
    Curr Allergy Asthma Rep 2:63-6. 2002
  3. ncbi request reprint Hidden food allergens
    S L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, Lincoln, Nebraska, USA
    Curr Opin Allergy Clin Immunol 1:269-71. 2001
  4. ncbi request reprint Validated sandwich enzyme-linked immunosorbent assay for casein and its application to retail and milk-allergic complaint foods
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska Lincoln, Department of Food Science and Technology, Lincoln, Nebraska 68583 0919, USA
    J Food Prot 67:1933-8. 2004
  5. ncbi request reprint Food allergy and the food industry
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, 143 H C Filley Hall, Lincoln, NE 68583 0919, USA
    Curr Allergy Asthma Rep 4:55-9. 2004
  6. doi request reprint Sandwich enzyme-linked immunosorbent assay (ELISA) for the detection of lupine residues in foods
    C H Kaw
    Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
    J Food Sci 73:T135-40. 2008
  7. ncbi request reprint Ingredient and labeling issues associated with allergenic foods
    S L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Department of Food Science and Technology, Lincoln, Nebraska, USA
    Allergy 56:64-9. 2001
  8. doi request reprint Sandwich enzyme-linked immunosorbent assay (ELISA) for detection of mustard in foods
    P W Lee
    Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
    J Food Sci 73:T62-8. 2008
  9. ncbi request reprint Will genetically modified foods be allergenic?
    S L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Lincoln, USA
    J Allergy Clin Immunol 107:765-71. 2001
  10. ncbi request reprint Assessing genetically modified crops to minimize the risk of increased food allergy: a review
    Richard E Goodman
    Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE 68583 0955, USA
    Int Arch Allergy Immunol 137:153-66. 2005

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Development of a sandwich enzyme-linked immunosorbent assay for the detection of egg residues in processed foodst
    S L Hefle
    University of Nebraska Lincoln, Department of Food Science and Technology, 68583 0919, USA
    J Food Prot 64:1812-6. 2001
    ..This sandwich-type ELISA method can be used to detect undeclared egg residues in processed foods and to evaluate industrial clean-up operations...
  2. ncbi request reprint How much food is too much? Threshold doses for allergenic foods
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, 351 Food Industry Complex, Lincoln, NE 68583 0919, USA
    Curr Allergy Asthma Rep 2:63-6. 2002
    ....
  3. ncbi request reprint Hidden food allergens
    S L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, Lincoln, Nebraska, USA
    Curr Opin Allergy Clin Immunol 1:269-71. 2001
    ....
  4. ncbi request reprint Validated sandwich enzyme-linked immunosorbent assay for casein and its application to retail and milk-allergic complaint foods
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska Lincoln, Department of Food Science and Technology, Lincoln, Nebraska 68583 0919, USA
    J Food Prot 67:1933-8. 2004
    ..This ELISA method provides a useful quality control tool for the food industry and could also be used as a validation of kosher-pareve status...
  5. ncbi request reprint Food allergy and the food industry
    Susan L Hefle
    Food Allergy Research and Resource Program, University of Nebraska, 143 H C Filley Hall, Lincoln, NE 68583 0919, USA
    Curr Allergy Asthma Rep 4:55-9. 2004
    ..Additional research to determine eliciting doses for allergenic foods is needed to enable science-based risk assessment and risk management...
  6. doi request reprint Sandwich enzyme-linked immunosorbent assay (ELISA) for the detection of lupine residues in foods
    C H Kaw
    Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
    J Food Sci 73:T135-40. 2008
    ..8% and 103.1%+/- 11.5%, respectively. The sandwich-type lupine ELISA developed in this study provides food manufacturers and regulatory agencies with an effective analytical tool to detect and quantify lupine residues in processed foods...
  7. ncbi request reprint Ingredient and labeling issues associated with allergenic foods
    S L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Department of Food Science and Technology, Lincoln, Nebraska, USA
    Allergy 56:64-9. 2001
    ..Food manufacturers should declare the presence of allergenic food ingredients in the ingredient listings on product labels so that allergic consumers can know to avoid these potentially hazardous products...
  8. doi request reprint Sandwich enzyme-linked immunosorbent assay (ELISA) for detection of mustard in foods
    P W Lee
    Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
    J Food Sci 73:T62-8. 2008
    ..This sandwich-type ELISA can serve as a powerful tool for food manufacturers and regulatory agencies to detect and quantify mustard residues in processed foods...
  9. ncbi request reprint Will genetically modified foods be allergenic?
    S L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Lincoln, USA
    J Allergy Clin Immunol 107:765-71. 2001
    ..Applying such criteria provides reasonable assurance that the newly introduced protein has limited capability to become an allergen...
  10. ncbi request reprint Assessing genetically modified crops to minimize the risk of increased food allergy: a review
    Richard E Goodman
    Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE 68583 0955, USA
    Int Arch Allergy Immunol 137:153-66. 2005
    ..Based on the evidence to date, the current assessment process has worked well to prevent the unintended introduction of allergens in commercial GM crops...
  11. ncbi request reprint Genetically engineered foods: implications for food allergy
    Steve L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Lincoln, Nebraska 68583 0919, USA
    Curr Opin Allergy Clin Immunol 2:249-52. 2002
    ..However, the adequacy of the current approach to the assessment of the potential allergenicity of foods produced through agricultural biotechnology has been the subject of considerable scientific and regulatory debate...
  12. ncbi request reprint A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?
    S L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Lincoln, NE 68583, USA
    Clin Exp Allergy 34:689-95. 2004
    ..While low-dose challenge trials have been conducted on an appreciable number of allergic individuals, a variety of different clinical protocols were used making the estimation of the threshold dose very difficult...
  13. ncbi request reprint Tagatose and milk allergy
    S L Taylor
    Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE 68583 0919, USA
    Allergy 60:412-3. 2005
  14. doi request reprint Detection of walnut residues in foods using an enzyme-linked immunosorbent assay
    Lynn Niemann
    Food Allergy Research and Resource Program, Dept of Food Science and Technology, Univ of Nebraska Lincoln, Lincoln, NE 68583 0919, USA
    J Food Sci 74:T51-7. 2009
    ..This walnut ELISA can be used to detect undeclared walnut residues in foods and ingredients and as a tool to validate the effectiveness of allergen control programs for walnuts...
  15. ncbi request reprint Factors affecting the determination of threshold doses for allergenic foods: how much is too much?
    Steve L Taylor
    University of Nebraska, Food Allergy Research and Resource Program, Lincoln 68583 0919, USA
    J Allergy Clin Immunol 109:24-30. 2002
    ..Are these very low, residual quantities hazardous to allergic consumers? How much of the offending food is too much? Very little quantitative information exists to allow any risk assessments to be conducted by the food industry...
  16. ncbi request reprint Consumer attitudes and risks associated with packaged foods having advisory labeling regarding the presence of peanuts
    Susan L Hefle
    Food Allergy Research and Resource Program, Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68583 0919, USA
    J Allergy Clin Immunol 120:171-6. 2007
    ..Foods with advisory labeling (eg, "may contain") are increasingly prevalent. Consumers with food allergies might ignore advisory labeling advice...
  17. ncbi request reprint Ara h 8, a Bet v 1-homologous allergen from peanut, is a major allergen in patients with combined birch pollen and peanut allergy
    Diana Mittag
    Department of Dermatology, University Hospital, Zurich
    J Allergy Clin Immunol 114:1410-7. 2004
    ..We recently described patients with soybean allergy mainly mediated by cross-reactivity to birch pollen allergens. A majority of those patients were reported to have peanut allergy...
  18. ncbi request reprint Bioinformatic methods for allergenicity assessment using a comprehensive allergen database
    Ronald E Hileman
    Monsanto Company, Product Safety Center, St Louis, MO, USA
    Int Arch Allergy Immunol 128:280-91. 2002
    ....
  19. ncbi request reprint Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized children
    Annebeth E Flinterman
    Department of Dermatology Allergology, University Medical Center, Utrecht, The Netherlands
    J Allergy Clin Immunol 117:448-54. 2006
    ..For future regulatory and industry guidelines, information on no-observed-adverse-effect levels (NOAELs) and eliciting doses (EDs) for allergenic foods is necessary...
  20. ncbi request reprint IgE binding to pepsin-digested food extracts
    Jaap H Akkerdaas
    Sanquin Research, Department of Immunopathology and Laboratory for Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Int Arch Allergy Immunol 138:203-8. 2005
    ..However, for many foods, purified allergens are not (yet) available...
  21. ncbi request reprint A randomized, double-blinded, placebo-controlled oral challenge study to evaluate the allergenicity of commercial, food-grade fish gelatin
    Tine K Hansen
    Allergy Center, Odense University Hospital, Sdr Boulevard 29, DK 5000 Odense C, Denmark
    Food Chem Toxicol 42:2037-44. 2004
    ..Fish gelatin is extracted from the skin of fish species known to elicit allergic reactions in sensitized individuals...
  22. ncbi request reprint A novel approach for the detection of potentially hazardous pepsin stable hazelnut proteins as contaminants in chocolate-based food
    Jaap H Akkerdaas
    Sanquin Research, Department of Immunopathology and Laboratory for Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, 1066 CX Amsterdam, The Netherlands
    J Agric Food Chem 52:7726-31. 2004
    ..It can be concluded that the application of antibodies directed to pepsin-digested food extracts in ELISA can facilitate specific detection of stable proteins that have the highest potential of inducing severe food anaphylaxis...
  23. ncbi request reprint Proteolytic processing of the peanut allergen Ara h 3
    Sander R Piersma
    FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands
    Mol Nutr Food Res 49:744-55. 2005
    ....
  24. ncbi request reprint The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergy
    Marjolein Wensing
    Department of Dermatology Allergology, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Allergy Clin Immunol 110:915-20. 2002
    ..Individual threshold doses for eliciting allergic reactions need to be elucidated to assess the risks for development of allergic reactions after accidental ingestion of peanut in a population with peanut allergy...
  25. ncbi request reprint Detection of soy proteins in processed foods: literature overview and new experimental work
    Stef J Koppelman
    TNO Nutrition and Food Research, Zeist, The Netherlands
    J AOAC Int 87:1398-407. 2004
    ..The presently developed test is applicable for soy ingredients and soy-containing foods that are processed in different ways. The limit of quantitation is 1 ppm, which is an enormous improvement over earlier described methods...
  26. ncbi request reprint Reversible denaturation of Brazil nut 2S albumin (Ber e1) and implication of structural destabilization on digestion by pepsin
    Stef J Koppelman
    TNO Nutrition and Food Research, Zeist, The Netherlands
    J Agric Food Chem 53:123-31. 2005
    ..Whereas native 2S albumin was digested slowly in 1 h, the reduced and alkylated protein was digested completely within 30 s. These results are discussed in view of the potential allergenicity of Brazil nut 2S albumin...