Research Topics
| S L HefleSummaryAffiliation: University of Nebraska Country: USA Publications
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Detail Information
Publications
Development of a sandwich enzyme-linked immunosorbent assay for the detection of egg residues in processed foodstS L Hefle
University of Nebraska Lincoln, Department of Food Science and Technology, 68583 0919, USA
J Food Prot 64:1812-6. 2001..This sandwich-type ELISA method can be used to detect undeclared egg residues in processed foods and to evaluate industrial clean-up operations...- How much food is too much? Threshold doses for allergenic foodsSusan L Hefle
Food Allergy Research and Resource Program, University of Nebraska, 351 Food Industry Complex, Lincoln, NE 68583 0919, USA
Curr Allergy Asthma Rep 2:63-6. 2002.... - Hidden food allergensS L Hefle
Food Allergy Research and Resource Program, University of Nebraska, Lincoln, Nebraska, USA
Curr Opin Allergy Clin Immunol 1:269-71. 2001.... - Validated sandwich enzyme-linked immunosorbent assay for casein and its application to retail and milk-allergic complaint foodsSusan L Hefle
Food Allergy Research and Resource Program, University of Nebraska Lincoln, Department of Food Science and Technology, Lincoln, Nebraska 68583 0919, USA
J Food Prot 67:1933-8. 2004..This ELISA method provides a useful quality control tool for the food industry and could also be used as a validation of kosher-pareve status... - Food allergy and the food industrySusan L Hefle
Food Allergy Research and Resource Program, University of Nebraska, 143 H C Filley Hall, Lincoln, NE 68583 0919, USA
Curr Allergy Asthma Rep 4:55-9. 2004..Additional research to determine eliciting doses for allergenic foods is needed to enable science-based risk assessment and risk management... 
Sandwich enzyme-linked immunosorbent assay (ELISA) for the detection of lupine residues in foodsC H Kaw
Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
J Food Sci 73:T135-40. 2008..8% and 103.1%+/- 11.5%, respectively. The sandwich-type lupine ELISA developed in this study provides food manufacturers and regulatory agencies with an effective analytical tool to detect and quantify lupine residues in processed foods...- Ingredient and labeling issues associated with allergenic foodsS L Taylor
University of Nebraska, Food Allergy Research and Resource Program, Department of Food Science and Technology, Lincoln, Nebraska, USA
Allergy 56:64-9. 2001..Food manufacturers should declare the presence of allergenic food ingredients in the ingredient listings on product labels so that allergic consumers can know to avoid these potentially hazardous products... - Sandwich enzyme-linked immunosorbent assay (ELISA) for detection of mustard in foodsP W Lee
Food Allergy Research and Resource Program, Univ of Nebraska, 143 Food Industry Complex, Lincoln, NE 68583 0919, USA
J Food Sci 73:T62-8. 2008..This sandwich-type ELISA can serve as a powerful tool for food manufacturers and regulatory agencies to detect and quantify mustard residues in processed foods... - Will genetically modified foods be allergenic?S L Taylor
University of Nebraska, Food Allergy Research and Resource Program, Lincoln, USA
J Allergy Clin Immunol 107:765-71. 2001..Applying such criteria provides reasonable assurance that the newly introduced protein has limited capability to become an allergen... - Assessing genetically modified crops to minimize the risk of increased food allergy: a reviewRichard E Goodman
Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE 68583 0955, USA
Int Arch Allergy Immunol 137:153-66. 2005..Based on the evidence to date, the current assessment process has worked well to prevent the unintended introduction of allergens in commercial GM crops... - Genetically engineered foods: implications for food allergySteve L Taylor
University of Nebraska, Food Allergy Research and Resource Program, Lincoln, Nebraska 68583 0919, USA
Curr Opin Allergy Clin Immunol 2:249-52. 2002..However, the adequacy of the current approach to the assessment of the potential allergenicity of foods produced through agricultural biotechnology has been the subject of considerable scientific and regulatory debate... - A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?S L Taylor
University of Nebraska, Food Allergy Research and Resource Program, Lincoln, NE 68583, USA
Clin Exp Allergy 34:689-95. 2004..While low-dose challenge trials have been conducted on an appreciable number of allergic individuals, a variety of different clinical protocols were used making the estimation of the threshold dose very difficult... - Tagatose and milk allergyS L Taylor
Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE 68583-0919, USA
Allergy 60:412-3. 2005 - Detection of walnut residues in foods using an enzyme-linked immunosorbent assayLynn Niemann
Food Allergy Research and Resource Program, Dept of Food Science and Technology, Univ of Nebraska Lincoln, Lincoln, NE 68583 0919, USA
J Food Sci 74:T51-7. 2009..This walnut ELISA can be used to detect undeclared walnut residues in foods and ingredients and as a tool to validate the effectiveness of allergen control programs for walnuts... - Factors affecting the determination of threshold doses for allergenic foods: how much is too much?Steve L Taylor
University of Nebraska, Food Allergy Research and Resource Program, Lincoln 68583 0919, USA
J Allergy Clin Immunol 109:24-30. 2002..Are these very low, residual quantities hazardous to allergic consumers? How much of the offending food is too much? Very little quantitative information exists to allow any risk assessments to be conducted by the food industry... - Consumer attitudes and risks associated with packaged foods having advisory labeling regarding the presence of peanutsSusan L Hefle
Food Allergy Research and Resource Program, Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68583 0919, USA
J Allergy Clin Immunol 120:171-6. 2007..Foods with advisory labeling (eg, "may contain") are increasingly prevalent. Consumers with food allergies might ignore advisory labeling advice... - Ara h 8, a Bet v 1-homologous allergen from peanut, is a major allergen in patients with combined birch pollen and peanut allergyDiana Mittag
Department of Dermatology, University Hospital, Zurich
J Allergy Clin Immunol 114:1410-7. 2004..CONCLUSIONS: Peanut allergy might be mediated in a subgroup of our patients by means of cross-reaction of Bet v 1 with the homologous peanut allergen Ara h 8... - Bioinformatic methods for allergenicity assessment using a comprehensive allergen databaseRonald E Hileman
Monsanto Company, Product Safety Center, St. Louis, MO, USA
Int Arch Allergy Immunol 128:280-91. 2002..An additional search for matches of 8 amino acids may provide an added margin of safety when assessing the potential allergenicity of a protein, but a search with a 6-amino-acid window produces many random, irrelevant matches... - Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized childrenAnnebeth E Flinterman
Department of Dermatology Allergology, University Medical Center, Utrecht, The Netherlands
J Allergy Clin Immunol 117:448-54. 2006..For future regulatory and industry guidelines, information on no-observed-adverse-effect levels (NOAELs) and eliciting doses (EDs) for allergenic foods is necessary... - IgE binding to pepsin-digested food extractsJaap H Akkerdaas
Sanquin Research, Department of Immunopathology and Laboratory for Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Int Arch Allergy Immunol 138:203-8. 2005..This can increase the clinical prognostic value of food allergy serology... - A randomized, double-blinded, placebo-controlled oral challenge study to evaluate the allergenicity of commercial, food-grade fish gelatinTine K Hansen
Allergy Center, Odense University Hospital, Sdr Boulevard 29, DK 5000 Odense C, Denmark
Food Chem Toxicol 42:2037-44. 2004..Fish gelatin is extracted from the skin of fish species known to elicit allergic reactions in sensitized individuals... - A novel approach for the detection of potentially hazardous pepsin stable hazelnut proteins as contaminants in chocolate-based foodJaap H Akkerdaas
Sanquin Research, Department of Immunopathology and Laboratory for Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, 1066 CX Amsterdam, The Netherlands
J Agric Food Chem 52:7726-31. 2004..It can be concluded that the application of antibodies directed to pepsin-digested food extracts in ELISA can facilitate specific detection of stable proteins that have the highest potential of inducing severe food anaphylaxis... - Proteolytic processing of the peanut allergen Ara h 3Sander R Piersma
FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands
Mol Nutr Food Res 49:744-55. 2005.... - The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergyMarjolein Wensing
Department of Dermatology/Allergology, University Medical Centre Utrecht, Utrecht, The Netherlands
J Allergy Clin Immunol 110:915-20. 2002..This is even more important because patients with severe reactions react to lower doses than patients with mild symptoms... - Detection of soy proteins in processed foods: literature overview and new experimental workStef J Koppelman
TNO Nutrition and Food Research, Zeist, The Netherlands
J AOAC Int 87:1398-407. 2004..The presently developed test is applicable for soy ingredients and soy-containing foods that are processed in different ways. The limit of quantitation is 1 ppm, which is an enormous improvement over earlier described methods... - Reversible denaturation of Brazil nut 2S albumin (Ber e1) and implication of structural destabilization on digestion by pepsinStef J Koppelman
TNO Nutrition and Food Research, Zeist, The Netherlands
J Agric Food Chem 53:123-31. 2005..Whereas native 2S albumin was digested slowly in 1 h, the reduced and alkylated protein was digested completely within 30 s. These results are discussed in view of the potential allergenicity of Brazil nut 2S albumin...