Dale J Hedges

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Comparison of three targeted enrichment strategies on the SOLiD sequencing platform
    Dale J Hedges
    John T MacDonald Department of Human Genetics, Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 6:e18595. 2011
  2. pmc Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci
    Dale J Hedges
    Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10 Ave, M 860, Miami, FL 33136, USA
    Mol Autism 3:2. 2012
  3. pmc Evaluating mitochondrial DNA variation in autism spectrum disorders
    Athena Hadjixenofontos
    John P Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
    Ann Hum Genet 77:9-21. 2013
  4. pmc Exome sequencing of a multigenerational human pedigree
    Dale J Hedges
    John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 4:e8232. 2009
  5. pmc An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males
    Ren Hua Chung
    Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, PO Box 019132 M 860, Miami, FL 33101, USA
    Mol Autism 2:18. 2011
  6. doi request reprint Sample degradation leads to false-positive copy number variation calls in multiplex real-time polymerase chain reaction assays
    HOLLY N CUKIER
    Miami Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Anal Biochem 386:288-90. 2009
  7. pmc A genome-wide association study of autism reveals a common novel risk locus at 5p14.1
    Deqiong Ma
    Miami Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, FL, USA
    Ann Hum Genet 73:263-73. 2009

Collaborators

Detail Information

Publications7

  1. pmc Comparison of three targeted enrichment strategies on the SOLiD sequencing platform
    Dale J Hedges
    John T MacDonald Department of Human Genetics, Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 6:e18595. 2011
    ..Both Raindance and Nimblegen SeqCap exhibited tighter distributions of read depth around the mean, but both suffered from lower on-target efficiency in our experiments. Raindance demonstrated the highest versatility in assay design...
  2. pmc Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci
    Dale J Hedges
    Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10 Ave, M 860, Miami, FL 33136, USA
    Mol Autism 3:2. 2012
    ..abstract:..
  3. pmc Evaluating mitochondrial DNA variation in autism spectrum disorders
    Athena Hadjixenofontos
    John P Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
    Ann Hum Genet 77:9-21. 2013
    ..Accordingly, while there may be attractive biological hints suggesting the role of mitochondria in ASD our data indicate that mtDNA variation is not a major contributing factor to the development of ASD...
  4. pmc Exome sequencing of a multigenerational human pedigree
    Dale J Hedges
    John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 4:e8232. 2009
    ....
  5. pmc An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males
    Ren Hua Chung
    Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, PO Box 019132 M 860, Miami, FL 33101, USA
    Mol Autism 2:18. 2011
    ..abstract:..
  6. doi request reprint Sample degradation leads to false-positive copy number variation calls in multiplex real-time polymerase chain reaction assays
    HOLLY N CUKIER
    Miami Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Anal Biochem 386:288-90. 2009
    ..Results suggest the possibility of biased degradation among genomic regions and emphasize the need to assess sample integrity immediately prior to real-time qPCR experiments...
  7. pmc A genome-wide association study of autism reveals a common novel risk locus at 5p14.1
    Deqiong Ma
    Miami Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, FL, USA
    Ann Hum Genet 73:263-73. 2009
    ..24E-04 to 3.40E-06) than in either dataset alone. Our findings demonstrate that in addition to multiple rare variations, part of the complex genetic architecture of autism involves common variation...