C L Heaps
Affiliation: University of Missouri
- Enhanced L-type Ca2+ channel current density in coronary smooth muscle of exercise-trained pigs is compensated to limit myoplasmic free Ca2+ accumulationC L Heaps
Dalton Cardiovascular Research Center and Department of Physiology, University of Missouri, Columbia, MO 65211, USA
J Physiol 528:435-45. 2000..Additional potential compensatory mechanisms include Ca2+ extrusion via plasma membrane Ca2+-ATPase, mitochondrial uptake, myoplasmic Ca2+-binding proteins and other sources of VGCC inactivation...
- Sarcoplasmic reticulum Ca(2+) uptake is impaired in coronary smooth muscle distal to coronary occlusionC L Heaps
Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211, USA
Am J Physiol Heart Circ Physiol 281:H223-31. 2001..Impaired SR Ca(2+) uptake was independent of SERCA protein levels and was not prevented by exercise training...
- Calcium buffering in coronary smooth muscle after chronic occlusion and exercise trainingJ J Jones
Vascular Biology Laboratory, Dalton Cardiovascular Research Center, and Department of Physiology, University of Missouri, Columbia, MO 65211, USA
Cardiovasc Res 51:359-67. 2001....
- Hypercholesterolemia abolishes voltage-dependent K+ channel contribution to adenosine-mediated relaxation in porcine coronary arteriolesC L Heaps
Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
Am J Physiol Heart Circ Physiol 288:H568-76. 2005....
- Endogenous testosterone increases L-type Ca2+ channel expression in porcine coronary smooth muscleD K Bowles
E102 Veterinary Medicine, Univ of Missouri, Columbia, MO 65211, USA
Am J Physiol Heart Circ Physiol 287:H2091-8. 2004..2 expression. Furthermore, this effect was blocked by the androgen receptor antagonist cyproterone. We conclude that endogenous testosterone is a primary regulator of Cav1.2 expression and activity in coronary arteries of males...
- Hypercholesterolemia inhibits L-type calcium current in coronary macro-, not microcirculationD K Bowles
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA
J Appl Physiol 96:2240-8. 2004..The inhibition of calcium channel activity in CASM of large coronary arteries is likely due to increases in membrane free cholesterol...