Research Topics
Species | Ka HeSummaryAffiliation: University of North Carolina Country: USA Publications
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Publications
Intakes of long-chain n-3 polyunsaturated fatty acids and fish in relation to measurements of subclinical atherosclerosisKa He
Department of Nutrition, School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Am J Clin Nutr 88:1111-8. 2008..Data on the relations of different types of fish meals and long-chain n-3 polyunsaturated fatty acids (PUFAs) to measures of atherosclerosis are sparse...
The puzzle of dietary fat intake and risk of ischemic stroke: a brief review of epidemiologic dataKa He
Department of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
J Am Diet Assoc 107:287-95. 2007..Future investigations are needed to examine the effects of fatty acids on subtype of ischemic stroke and to clarify the possible differences of dietary fat in relation to ischemic stroke and CHD...
Associations of dietary long-chain n-3 polyunsaturated fatty acids and fish with biomarkers of inflammation and endothelial activation (from the Multi-Ethnic Study of Atherosclerosis [MESA])Ka He
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Am J Cardiol 103:1238-43. 2009..These results may partially explain the cardioprotective effects of fish consumption...
Trace elements in nails as biomarkers in clinical researchKa He
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7461, USA
Eur J Clin Invest 41:98-102. 2011..The importance of trace elements in relation to human health has been increasingly recognized. Accurate and adequate quantification of trace elements are crucial in clinical research...
Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease--eat fish or take fish oil supplement?Ka He
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Prog Cardiovasc Dis 52:95-114. 2009..Further studies are needed to investigate the potential adverse effects of contaminants in fish and the possible different effects from different types of fish and cooking methods...
Consumption of monosodium glutamate in relation to incidence of overweight in Chinese adults: China Health and Nutrition Survey (CHNS)Ka He
Departments of Nutrition and Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Clin Nutr 93:1328-36. 2011..It has been hypothesized that monosodium glutamate (MSG), a flavor enhancer, is positively associated with weight gain, which influences energy balance through the disruption of the hypothalamic signaling cascade of leptin action...
Folate intake and incidence of hypertension among American young adults: a 20-y follow-up studyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Am J Clin Nutr 95:1023-30. 2012..However, human studies, particularly longitudinal data, are limited...
Intakes of long-chain omega-3 (n-3) PUFAs and fish in relation to incidence of asthma among American young adults: the CARDIA studyJingjing Li
Departments of Epidemiology and Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
Am J Clin Nutr 97:173-8. 2013..Although long-chain ω-3 (n-3) PUFAs (LCω3PUFAs) have been linked to the prevention of some inflammatory disorders, little is known about the association between these fatty acids and incidence of asthma...
Associations of toenail selenium levels with inflammatory biomarkers of fibrinogen, high-sensitivity c-reactive protein, and interleukin-6: The CARDIA Trace Element StudyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Am J Epidemiol 171:793-800. 2010..Gender, race/ethnicity, smoking status, and selenium supplementation did not appreciably modify these results. This study found no associations between toenail selenium and inflammation as measured by fibrinogen, hs-CRP, and IL-6...
Longitudinal association between toenail selenium levels and measures of subclinical atherosclerosis: the CARDIA trace element studyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Atherosclerosis 210:662-7. 2010..To examine the longitudinal association between toenail selenium levels and subclinical atherosclerosis over an 18-year period...
Folate, vitamin B6, and B12 intakes in relation to risk of stroke among menKa He
Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
Stroke 35:169-74. 2004..However, the effects of intakes of these vitamins on risk of stroke are still uncertain. This study examines intakes of folate, vitamin B6, and B12 in relation to risk of ischemic and hemorrhagic stroke...
Antioxidant intake and pancreatic cancer risk: the Vitamins and Lifestyle (VITAL) StudyXuesong Han
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Cancer 119:1314-20. 2013..In this study, the authors examined the intake of antioxidants from diet and supplements in relation to pancreatic cancer risk among participants of the Vitamins and Lifestyle (VITAL) Study...
Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based studyBo Qin
University of North Carolina, Chapel Hill, USA
Arthritis Care Res (Hoboken) 64:1306-11. 2012..To examine the cross-sectional association between dietary magnesium intake and radiographic knee osteoarthritis (OA) among African American and white men and women...
Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studiesKa He
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1102, Chicago, Ill 60611, USA
Circulation 109:2705-11. 2004..Results from observational studies on fish consumption and coronary heart disease (CHD) mortality are inconsistent...
Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort studyKa He
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
BMJ 327:777-82. 2003..To examine the association between intake of total fat, specific types of fat, and cholesterol and risk of stroke in men. Design and setting Health professional follow up study with 14 year follow up...
Fasting insulin level is positively associated with incidence of hypertension among American young adults: a 20-year follow-up studyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Diabetes Care 35:1532-7. 2012..We examined the relation between fasting insulin and incidence of HTN in a large prospective cohort...
Longitudinal association between animal and vegetable protein intake and obesity among men in the United States: the Chicago Western Electric StudyDeborah Bujnowski
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC 2759, USA
J Am Diet Assoc 111:1150-1155.e1. 2011..Literature on the association of protein intake with body weight is inconsistent. Little is known about the relation of long-term protein intake to obesity...
Distributions and determinants of mercury concentrations in toenails among American young adults: the CARDIA Trace Element StudyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, 2221 McGavran Greenberg, Campus Box 7461, Chapel Hill, NC 27599, USA
Environ Sci Pollut Res Int 20:1423-30. 2013..As fish consumption was the key determinant, avoiding certain types of fish that have relatively high Hg levels may be crucial in reducing Hg intake...
Types of fish consumed and fish preparation methods in relation to pancreatic cancer incidence: the VITAL Cohort StudyKa He
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Am J Epidemiol 177:152-60. 2013..LC-PUFAs, particularly docosahexaenoic acid, and nonfried fish, but not shellfish or fried fish, may be beneficial in the primary prevention of pancreatic cancer...
Are the 2005 Dietary Guidelines for Americans Associated With reduced risk of type 2 diabetes and cardiometabolic risk factors? Twenty-year findings from the CARDIA studyDAISY ZAMORA
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Diabetes Care 34:1183-5. 2011..To examine the prospective association between accordance with the 2005 Dietary Guidelines for Americans (DGA) and subsequent diabetes incidence and changes in cardiometabolic risk factors...
Higher branched-chain amino acid intake is associated with a lower prevalence of being overweight or obese in middle-aged East Asian and Western adultsLi Qiang Qin
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
J Nutr 141:249-54. 2011..03). In conclusion, higher dietary BCAA intake is associated with lower prevalence of overweight status/obesity among apparently healthy middle-aged adults from East Asian and Western countries...
The association between body mass index and hypertension is different between East and Southeast AsiansTuan T Nguyen
Department of Nutrition, University of North Carolina at Chapel Hill, NC 27516 3997, USA
Am J Clin Nutr 89:1905-12. 2009..Few studies have allowed direct comparison of the association between body mass index (BMI; in kg/m2) and hypertension in different Asian ethnicities...
Association of monosodium glutamate intake with overweight in Chinese adults: the INTERMAP StudyKa He
Department of Nutrition, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Obesity (Silver Spring) 16:1875-80. 2008..03) and 2.75 (95% confidence interval, 1.28-5.95, P = 0.04). This research provides data that MSG intake may be associated with increased risk of overweight independent of physical activity and total energy intake in humans...
Fish consumption and incidence of stroke: a meta-analysis of cohort studiesKa He
Department of Preventive Medicine, The Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611, USA
Stroke 35:1538-42. 2004..Results from observational studies on fish consumption and risk of stroke are inconsistent. We quantitatively assessed the relationship between fish intake and incidence of stroke using a meta-analysis of cohort studies...
Fish Consumption and Incidence of Diabetes: meta-analysis of data from 438,000 individuals in 12 independent prospective cohorts with an average 11-year follow-upPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Diabetes Care 35:930-8. 2012..However, epidemiological data on fish intake and diabetes incidence are controversial and inconclusive. Therefore, we aimed to assess the literature and determine the association between fish consumption and diabetes risk quantitatively...
Magnesium intake in relation to systemic inflammation, insulin resistance, and the incidence of diabetesDae Jung Kim
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Diabetes Care 33:2604-10. 2010..To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young American adults...
Distribution of toenail selenium levels in young adult Caucasians and African Americans in the United States: the CARDIA Trace Element StudyPengcheng Xun
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, 2221 McGavran Greenberg, Campus Box 7461, Chapel Hill, NC 27599, USA
Environ Res 111:514-9. 2011..Data on selenium (Se) levels in American young adults, especially in African Americans, are lacking...
Predictors of measurement error in energy intake during pregnancyEric Nowicki
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, 27599 7435, USA
Am J Epidemiol 173:560-8. 2011..LER and HER are prevalent during pregnancy. Identifying their predictors may improve data collection and analytic methods for reducing systematic bias in the study of diet and reproductive outcomes...
Magnesium intake and incidence of metabolic syndrome among young adultsKa He
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Circulation 113:1675-82. 2006..However, the longitudinal association of magnesium intake and incidence of metabolic syndrome has not been investigated...
Magnesium intake and the metabolic syndrome: epidemiologic evidence to dateKa He
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Cardiometab Syndr 1:351-5. 2006..The purpose of this brief review is to summarize the epidemiologic data relating magnesium to the metabolic syndrome and to discuss the potential mechanisms...
Higher dietary intake of long-chain omega-3 polyunsaturated fatty acids is inversely associated with depressive symptoms in womenLaura A Colangelo
Department of Preventive Medicine, Feinberg School of Medicine, Chicago, Illinois, USA
Nutrition 25:1011-9. 2009....
Trans fat, aspirin, and ischemic stroke in postmenopausal womenSirin Yaemsiri
Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27599, USA
Ann Neurol 72:704-15. 2012..To examine the associations between dietary fat intake and ischemic stroke among postmenopausal women...
Magnesium physiology and pathogenic mechanisms that contribute to the development of the metabolic syndromeRashad J Belin
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Magnes Res 20:107-29. 2007..In this review, we describe and discuss the myriad of integrated physiological mechanisms through which magnesium deficiency and the resultant altered magnesium status may lead to the development of the MetS and each of its components...
Longitudinal trends in gasoline price and physical activity: the CARDIA studyNingqi Hou
Department of Nutrition, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA
Prev Med 52:365-9. 2011..To investigate longitudinal associations between community-level gasoline price and physical activity (PA)...
Optimal cutoff values for overweight: using body mass index to predict incidence of hypertension in 18- to 65-year-old Chinese adultsT Tuan Nguyen
Department of Nutrition, University of North Carolina, Chapel Hill, NC 27516, USA
J Nutr 138:1377-82. 2008..Our study supported the hypothesis that the BMI cutoff to define overweight should be lower in Chinese than that in Western populations...
Fish or long-chain (n-3) PUFA intake is not associated with pancreatic cancer risk in a meta-analysis and systematic reviewBo Qin
Department of Nutrition, Gillings Schools of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
J Nutr 142:1067-73. 2012..Further studies that consider different species and preparation methods of fish, and additional adjustment for contaminants in fish, are warranted...
Fish consumption and risk of stroke in menKa He
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA
JAMA 288:3130-6. 2002..The effect of fish consumption or long-chain omega-3 polyunsaturated fatty acid (PUFA) intake on risk of stroke remains uncertain...
Tracking of physical activity and inactivity in middle school girlsChris D Baggett
Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
Med Sci Sports Exerc 40:1916-22. 2008..The purpose of this study was to describe and compare the levels of tracking of physical activity and inactivity as assessed by self-report and accelerometry in middle school girls during a 2-yr period...
Defining and understanding healthy lifestyles choices for adolescentsKa He
Department of Preventive Medicine, Northwestern University School of Medicine, Chicago, Illinois 60611, USA
J Adolesc Health 35:26-33. 2004..To: (a) establish criteria for defining positive health behaviors and lifestyle; and (b) identify characteristics of adolescents who practice a healthy lifestyle...
p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagyShuang Mei
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina 27559, USA
J Biol Chem 287:11761-8. 2012..Together, our results provide brand new insight about cholesterol ester accumulation in macrophages and foam cell formation...
Effect of soy isoflavones on circulating C-reactive protein in postmenopausal women: meta-analysis of randomized controlled trialsJia Yi Dong
Department of Nutrition and Food Hygiene, School of Radiation Medicine and Public Health, Soochow University, Suzhou, China
Menopause 18:1256-62. 2011..However, soy isoflavones may produce a significant reduction in CRP among postmenopausal women with elevated CRP...
Dietary fat and stroke: a different story from coronary heart diseaseKa He
Ital Heart J 4:821-3. 2003
Food omega-3 fatty acid intake of individuals (total, linolenic acid, long-chain) and their blood pressure: INTERMAP studyHirotsugu Ueshima
Department of Health Science, Shiga University of Medical Science, Tsukinowa cho Seta, Otsu, Shiga 520 2192, Japan
Hypertension 50:313-9. 2007..In summary, food omega-3 PFA intake related inversely to blood pressure, including in nonhypertensive persons, with small estimated effect size. Food omega-3 PFA may contribute to prevention and control of adverse blood pressure levels...
Fish consumption in relation to stroke riskKa He
Neuroepidemiology 30:70. 2008
A few more thoughts about fish and fish oilKa He
J Am Diet Assoc 105:350-1. 2005
Risks and benefits of seafood consumptionKa He
Am J Prev Med 30:440-1. 2006
Risks and benefits of omega 3 fats: a few thoughts on systematic reviewKa He
BMJ 332:915; discussion 915-6. 2006
Research Grants
- Trace Elements and Cardiovascular Disease (CVD) Risks Factors Among Young AdultsKa He; Fiscal Year: 2007....
- Amino Acids, Protein, and BMI in Adults Across CulturesKa He; Fiscal Year: 2007..It is of great public health and clinical significance as obesity is a major health concern. The findings from this project may lead to new research on obesity prevention. ..
