Milan J Hazucha

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. doi request reprint Pulmonary responses in current smokers and ex-smokers following a two hour exposure at rest to clean air and fine ambient air particles
    Milan J Hazucha
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, CB 7310, 104 Mason Farm Road, Chapel Hill, NC 27599 7310, USA
    Part Fibre Toxicol 10:58. 2013
  2. ncbi request reprint Distribution and reproducibility of spirometric response to ozone by gender and age
    Milan J Hazucha
    Department of Medicine, School of Medicine, and the Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, North Carolina 27599 7310, USA
    J Appl Physiol (1985) 95:1917-25. 2003
  3. pmc Acute pulmonary function response to ozone in young adults as a function of body mass index
    William D Bennett
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Inhal Toxicol 19:1147-54. 2007
  4. pmc Mutations of DNAI1 in primary ciliary dyskinesia: evidence of founder effect in a common mutation
    Maimoona A Zariwala
    University of North Carolina at Chapel Hill 27599 7248, USA, and Department of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Germany
    Am J Respir Crit Care Med 174:858-66. 2006
  5. pmc Fluticasone propionate protects against ozone-induced airway inflammation and modified immune cell activation markers in healthy volunteers
    Neil E Alexis
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, North Carolina 27599 7310, USA
    Environ Health Perspect 116:799-805. 2008
  6. ncbi request reprint Characterization of spirometric function in residents of three comparison communities and of three communities located near waste incinerators in North Carolina
    Milan J Hazucha
    Center for Environmental Medicine and Lung Biology, University of North Carolina, Chapel Hill, North Carolina, USA
    Arch Environ Health 57:103-12. 2002
  7. doi request reprint Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers
    James M Samet
    Human Studies Division, National Health and Environmental Effects Research Laboratory, Research Triangle Park, Chapel Hill, NC 27599 7315, USA
    Am J Respir Crit Care Med 179:1034-42. 2009
  8. ncbi request reprint The effect of exercise on nasal uptake of ozone in healthy human adults
    Keegan Sawyer
    Center for Environmental Medicine, Asthma and Lung Biology, CB 7310, 104 Mason Farm Rd, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Appl Physiol 102:1380-6. 2007
  9. ncbi request reprint Respiratory damage in children exposed to urban pollution
    LILIAN CALDERON-GARCIDUENAS
    Environmental Pathology, University of North Carolina at Chapel Hill, North Carolina, USA
    Pediatr Pulmonol 36:148-61. 2003
  10. pmc Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Environ Health Perspect 115:1248-53. 2007

Collaborators

Detail Information

Publications12

  1. doi request reprint Pulmonary responses in current smokers and ex-smokers following a two hour exposure at rest to clean air and fine ambient air particles
    Milan J Hazucha
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, CB 7310, 104 Mason Farm Road, Chapel Hill, NC 27599 7310, USA
    Part Fibre Toxicol 10:58. 2013
    ..Increased susceptibility of smokers to ambient PM may potentially promote development of COPD and accelerate already present disease...
  2. ncbi request reprint Distribution and reproducibility of spirometric response to ozone by gender and age
    Milan J Hazucha
    Department of Medicine, School of Medicine, and the Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, North Carolina 27599 7310, USA
    J Appl Physiol (1985) 95:1917-25. 2003
    ..However, the mean delta%FEV1 differed by as much as six percentage points between exposure days. The yearly loss of responsiveness (0.2% to 0.7%/year) with progressing age determined by cross-sectional analyses was substantially smaller...
  3. pmc Acute pulmonary function response to ozone in young adults as a function of body mass index
    William D Bennett
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Inhal Toxicol 19:1147-54. 2007
    ..022). Although our population studied was predominantly normal weight, we found that higher body mass index may be a modest risk factor for adverse pulmonary effects associated with ozone exposure, especially for women...
  4. pmc Mutations of DNAI1 in primary ciliary dyskinesia: evidence of founder effect in a common mutation
    Maimoona A Zariwala
    University of North Carolina at Chapel Hill 27599 7248, USA, and Department of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Germany
    Am J Respir Crit Care Med 174:858-66. 2006
    ..Disease-causing mutations have been reported in DNAI1 and DNAH5 encoding outer dynein arm (ODA) proteins of cilia...
  5. pmc Fluticasone propionate protects against ozone-induced airway inflammation and modified immune cell activation markers in healthy volunteers
    Neil E Alexis
    Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, North Carolina 27599 7310, USA
    Environ Health Perspect 116:799-805. 2008
    ..High-dose inhaled corticosteroids can reduce O(3)-induced airway inflammation, but their effect on innate immune activation is unknown...
  6. ncbi request reprint Characterization of spirometric function in residents of three comparison communities and of three communities located near waste incinerators in North Carolina
    Milan J Hazucha
    Center for Environmental Medicine and Lung Biology, University of North Carolina, Chapel Hill, North Carolina, USA
    Arch Environ Health 57:103-12. 2002
    ....
  7. doi request reprint Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers
    James M Samet
    Human Studies Division, National Health and Environmental Effects Research Laboratory, Research Triangle Park, Chapel Hill, NC 27599 7315, USA
    Am J Respir Crit Care Med 179:1034-42. 2009
    ..Exposure to ambient ultrafine particles has been associated with cardiopulmonary toxicity and mortality. Adverse effects specifically linked to ultrafine particles include loss of sympathovagal balance and altered hemostasis...
  8. ncbi request reprint The effect of exercise on nasal uptake of ozone in healthy human adults
    Keegan Sawyer
    Center for Environmental Medicine, Asthma and Lung Biology, CB 7310, 104 Mason Farm Rd, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Appl Physiol 102:1380-6. 2007
    ..70 at 10 l/min) and 2) percent change in the rate of volumetric expansion between the nasal valve and turbinates (r = 0.82 at 10 l/min). These results may be useful for assessing human risk associated with ozone exposure during exercise...
  9. ncbi request reprint Respiratory damage in children exposed to urban pollution
    LILIAN CALDERON-GARCIDUENAS
    Environmental Pathology, University of North Carolina at Chapel Hill, North Carolina, USA
    Pediatr Pulmonol 36:148-61. 2003
    ..Consequently, these children are potentially at risk for developing chronic lung disease and other systemic effects later in life...
  10. pmc Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Environ Health Perspect 115:1248-53. 2007
    ..Controlled exposures of animals and humans to particulate matter (PM) or ozone air pollution cause an increase in plasma levels of endothelin-1, a potent vasoconstrictor that regulates pulmonary arterial pressure...
  11. pmc Lung radiology and pulmonary function of children chronically exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Environ Health Perspect 114:1432-7. 2006
    ..The epidemiologic implications of these findings are important for children residing in polluted environments, because bronchiolar disease could lead to chronic pulmonary disease later in life...
  12. ncbi request reprint Ozone enhances markers of innate immunity and antigen presentation on airway monocytes in healthy individuals
    John C Lay
    J Allergy Clin Immunol 120:719-22. 2007