Research Topics
| Kevin HaynesSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Temporal and within practice variability in the health improvement networkKevin Haynes
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Pharmacoepidemiol Drug Saf 20:948-55. 2011..However, little is known about the consistency within practices across observation years and among practices within a given year, in THIN or other large medical record databases...
Cancer incidence in The Health Improvement NetworkKevin Haynes
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 18:730-6. 2009..This study assessed whether the recorded incidence of cancer among patients in The Health Improvement Network (THIN) database is comparable to that expected in the UK based on national cancer registry data...
Inter-rater reliability of a classification system for hospital adverse drug event reportsK Haynes
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Clin Pharmacol Ther 83:485-8. 2008..Agreement on specific processes associated with ADEs ranged from poor to moderate, which limits the ability to target accurately processes to improve drug utilization...- Declining public health burden of digoxin toxicity from 1991 to 2004K Haynes
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Clin Pharmacol Ther 84:90-4. 2008..The public health burden of digoxin toxicity declined dramatically from 1991 to 2004 in the United Kingdom and the United States... - Increased risk of digoxin toxicity following hospitalizationKevin Haynes
Program for the Reduction in Medication Errors, Department of Biostatistics and Epidemiology and School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 18:28-35. 2009..The objective of the study was to identify health care system factors that affect the risk of digoxin toxicity for older adults on digoxin... - Effectiveness of an information technology intervention to improve prophylactic antibacterial use in the postoperative periodKevin Haynes
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Med Inform Assoc 18:164-8. 2011..Electronic order sets have shown promise as a means of integrating guideline information with electronic order entry systems and facilitating safer, more effective care... - Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug eventsCharles E Leonard
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Epidemiol 61:561-71. 2008..We sought to examine the validity of specific hospital discharge codes in identifying drug toxicity precipitating hospitalization, among elderly users of high-risk medications... - Patient reported receipt of medication instructions for warfarin is associated with reduced risk of serious bleeding eventsJoshua P Metlay
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Gen Intern Med 23:1589-94. 2008..Adverse drug events are an important cause of preventable hospitalizations... - Safety of saxagliptin: rationale for and design of a series of postmarketing observational studiesVincent Lo Re
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 21:1202-15. 2012..To describe the design and rationale of a series of postmarketing studies to examine the safety of saxagliptin, an oral dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes mellitus, in real-world settings... - Validity of The Health Improvement Network (THIN) for epidemiologic studies of hepatitis C virus infectionVincent Lo Re
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 18:807-14. 2009..We determined the accuracy of HCV diagnostic codes within The Health Improvement Network (THIN), an electronic database containing medical record data from general medical practices in the United Kingdom... - Association between longer therapy with thiazolidinediones and risk of bladder cancer: a cohort studyRonac Mamtani
Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Natl Cancer Inst 104:1411-21. 2012..In this study, we assessed the risk of bladder cancer associated with the use of TZDs and between pioglitazone and rosiglitazone, an alternative TZD... - Tumor necrosis factor α inhibitor therapy and cancer risk in chronic immune-mediated diseasesKevin Haynes
University of Pennsylvania, Department of Epidemiology and Biostatistics, Philadelphia, PA 19104, USA
Arthritis Rheum 65:48-58. 2013..To compare the incidence of cancer following tumor necrosis factor α (TNFα) inhibitor therapy to that with commonly used alternative therapies across multiple immune-mediated diseases... - Discontinuation rates of anticholinergic medications used for the treatment of lower urinary tract symptomsManish Gopal
Division of Urogynecology, University of Pennsylvania, Philadelphia, Pennsylvania 08901, USA
Obstet Gynecol 112:1311-8. 2008..To estimate the discontinuation rates of anticholinergic medications used for the treatment of lower urinary tract symptoms in women... - Validation of The Health Improvement Network (THIN) database for epidemiologic studies of chronic kidney diseaseMichelle R Denburg
Division of Nephrology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Pharmacoepidemiol Drug Saf 20:1138-49. 2011..The Health Improvement Network (THIN) in the UK represents a unique resource for population-based studies of CKD. We compiled a valid list of Read codes to identify subjects with moderate to advanced CKD... - Physician attitudes toward regionalization of adult critical care: a national surveyJeremy M Kahn
Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 37:2149-54. 2009..Regionalization has been proposed as a method to improve outcomes for patients with critical illness. We sought to determine intensivist physician attitudes and potential barriers to the regionalization of adult critical care... - Use of antiepileptic drugs in patients with kidney diseaseRubeen K Israni
Renal-Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 19:408-16. 2006..Monitoring of drug levels when available, careful clinical assessment of patients taking AEDs, and close collaboration with neurologists is essential to the management of patients taking AEDs... - Standards for head injury management in acute hospitals: evidence from the six million population of the Eastern regionH M Seeley
Neurosciences Department, Addenbrooke's Hospital, Cambridge, UK
Emerg Med J 23:128-32. 2006....