Research Topics
| J A HaymanSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Patient preferences concerning the trade-off between the risks and benefits of routine radiation therapy after conservative surgery for early-stage breast cancerJ A Hayman
Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
J Clin Oncol 15:1252-60. 1997..To assess patients' preferences regarding the trade-off between risks and benefits of radiation therapy after conservative surgery for early-stage breast cancer...- Estimating the costs of caring for the older breast cancer patientJames A Hayman
Department of Radiation Oncology, University of Michigan Health System, UH B2C490, Box 0010, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Crit Rev Oncol Hematol 46:255-60. 2003..The goals of this article will be to introduce the relevant types of costs, to review the available data on these costs and to conclude with some thoughts regarding areas for future research... - Use of palliative radiotherapy among patients with metastatic non-small-cell lung cancerJames A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 69:1001-7. 2007..The objective of this study was to examine the utilization patterns of palliative RT among elderly patients with Stage IV NSCLC and, in particular, to identify factors associated with its use... 
Measuring the quality of care in radiation oncologyJames A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Semin Radiat Oncol 18:201-6. 2008..We will next examine how these measures are currently being used and will conclude with some thoughts regarding the steps necessary to use quality measures to improve the quality of care in radiation oncology...- Assessing the benefit of radiation therapy after breast-conserving surgery for ductal carcinoma-in-situJames A Hayman
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109 0010, USA
J Clin Oncol 23:5171-7. 2005..To assess women's preferences regarding the trade-off between the risks and benefits of treatment with radiation therapy (RT) after breast-conserving surgery (BCS) for ductal carcinoma-in-situ (DCIS)... - Estimating the cost of informal caregiving for elderly patients with cancerJ A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor, 48109, USA
J Clin Oncol 19:3219-25. 2001..Although estimates of the associated direct medical costs exist, very little information is available regarding the prevalence, time, and cost associated with informal caregiving for elderly cancer patients... - Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy: update of a phase I trialJ A Hayman
Department of Radiation Oncology, Division of Hematology Oncology, University of Michigan Health System, Ann Arbor, MI, USA
J Clin Oncol 19:127-36. 2001..High-dose radiation may improve outcomes in non-small-cell lung cancer (NSCLC). By using three-dimensional conformal radiation therapy and limiting the target volume, we hypothesized that the dose could be safely escalated... - A comparison of two methods for estimating the technical costs of external beam radiation therapyJ A Hayman
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 47:461-7. 2000..The purpose of this study was to examine whether these competing approaches result in similar cost estimates for four typical courses of external beam radiation therapy (EBRT)... - Cost-effectiveness of adding an electron-beam boost to tangential radiation therapy in patients with negative margins after conservative surgery for early-stage breast cancerJ A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
J Clin Oncol 18:287-95. 2000..Electron-beam boosts (EBB) are routinely added after conservative surgery and tangential radiation therapy (TRT) for early-stage breast cancer. We performed an incremental cost-utility analysis to evaluate their cost-effectiveness... - Cost-effectiveness of routine radiation therapy following conservative surgery for early-stage breast cancerJ A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor 48109 0010, USA
J Clin Oncol 16:1022-9. 1998..To examine the cost-effectiveness of radiation therapy following conservative surgery for early-stage breast cancer... - Distribution of proliferating bone marrow in adult cancer patients determined using FLT-PET imagingJames A Hayman
Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
Int J Radiat Oncol Biol Phys 79:847-52. 2011..18F-fluoro-L-deoxythymidine concentrates in bone marrow, and we used its intensity on positron emission tomography imaging to quantify the location of the proliferating bone marrow... - Normal tissue complication probability modeling for acute esophagitis in patients treated with conformal radiation therapy for non-small cell lung cancerOlivier Chapet
Department of Radiation Oncology, University of Michigan, Ann Arbor, USA
Radiother Oncol 77:176-81. 2005..These new parameter values are supported in essence by the correlations found for the dose/volume threshold parameters... - Long-term results of conservative surgery and radiotherapy for ductal carcinoma in situ using lung density correction: the University of Michigan experienceMerav A Ben David
Department of Radiation Oncology, Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
Breast J 13:392-400. 2007.... - Do dose-volume metrics predict pulmonary function changes in lung irradiation?A M Allen
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 55:921-9. 2003..In addition, we wanted to examine the correlation between these metrics... - High radiation dose may reduce the negative effect of large gross tumor volume in patients with medically inoperable early-stage non-small cell lung cancerLujun Zhao
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 68:103-10. 2007..To determine whether the effect of radiation dose varies with gross tumor volume (GTV) in patients with stage I/II non-small cell lung cancer (NSCLC)... - Comparative survival in patients with postresection recurrent versus newly diagnosed non-small-cell lung cancer treated with radiotherapyXu Wei Cai
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 76:1100-5. 2010..To compare the survival of postresection recurrent vs. newly diagnosed non-small-cell lung cancer (NSCLC) patients treated with radiotherapy or chemoradiotherapy... 
Using fluorodeoxyglucose positron emission tomography to assess tumor volume during radiotherapy for non-small-cell lung cancer and its potential impact on adaptive dose escalation and normal tissue sparingMary Feng
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 73:1228-34. 2009....- The predictive role of plasma TGF-beta1 during radiation therapy for radiation-induced lung toxicity deserves further study in patients with non-small cell lung cancerLujun Zhao
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Lung Cancer 59:232-9. 2008..This study aimed to further investigate the role of circulating TGF-beta1 during radiation therapy (RT) in predicting radiation-induced lung toxicity (RILT)... - Time to treatment in patients with stage III non-small cell lung cancerLi Wang
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 74:790-5. 2009.... - A phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrencesW Warren Suh
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Breast J 10:204-10. 2004..This novel approach suggests excellent local-regional control when compared to historical controls. A phase II trial is warranted... - Three-dimensional conformal radiation may deliver considerable dose of incidental nodal irradiation in patients with early stage node-negative non-small cell lung cancer when the tumor is large and centrally locatedLujun Zhao
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109, USA
Radiother Oncol 82:153-9. 2007..To determine the dose to regional nodal stations in patients with T1-3N0M0 non-small cell lung cancer (NSCLC) treated with three-dimensional conformal radiation therapy (3DCRT) without intentional elective nodal irradiation (ENI)... - Overall survival after prostate-specific-antigen-detected recurrence following conformal radiation therapyH M Sandler
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 48:629-33. 2000..To study the significance, in terms of overall and cause-specific survival, of biochemical failure after conformal external-beam radiation therapy (RT) for prostate cancer... - Results following treatment to doses of 92.4 or 102.9 Gy on a phase I dose escalation study for non-small cell lung cancerSamir Narayan
Department of Radiation Oncology, University of California Davis Medical Center, 4501 X Street, G126, Sacramento, CA 95817, USA
Lung Cancer 44:79-88. 2004..The results of patients treated to either 92.4 or 102.9 Gy are reported... - The role of radiation therapy in thoracic tumorsFeng Ming Spring Kong
Department of Radiation Therapy, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Hematol Oncol Clin North Am 20:363-400. 2006.... - Short-term and long-term reproducibility of lung tumor position using active breathing control (ABC)Rojano Kashani
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 65:1553-9. 2006..To evaluate the short-term and long-term reproducibility of lung tumor position for scans acquired using an active breathing control (ABC) device... - Long-term results of three-dimensional conformal adjuvant and salvage radiotherapy after radical prostatectomyChristina Tsien
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
Urology 62:93-8. 2003..For patients receiving salvage RT, a Gleason score greater than 7 was predictive of prostate-specific antigen failure. Prospective trials are needed to improve further on these results... - Preliminary visual outcomes after three-dimensional conformal radiation therapy for optic nerve sheath meningiomaSamir Narayan
Department of Radiation Oncology, University of Michigan Health Care System, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 56:537-43. 2003..We assessed visual outcomes, local control, and toxicity associated with three-dimensional conformal radiation therapy (3D-CRT) for primary optic nerve sheath meningiomas (ONSM)... - A pilot study of [18F]fluorodeoxyglucose positron emission tomography scans during and after radiation-based therapy in patients with non small-cell lung cancerFeng Ming Spring Kong
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
J Clin Oncol 25:3116-23. 2007..To study whether changes of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) during treatment correlate with post-treatment responses in tumor and normal lung in patients with non-small-cell lung cancer (NSCLC)... - Neoadjuvant docetaxel and capecitabine and the use of thymidine phosphorylase as a predictive biomarker in breast cancerRachel M Layman
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109 0848, USA
Clin Cancer Res 13:4092-7. 2007..We evaluated whether TP protein expression is increased by docetaxel and correlates with pathologic complete response (pCR) in breast cancer patients... - The use of preferences to measure the benefit of adjuvant radiation therapy for stage I seminomaJune L Chan
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 53:934-41. 2002..The purpose of this study was to use utilities to assess the quality of life benefits associated with adjuvant RT in this setting... - Decision-analytic model and cost-effectiveness evaluation of postmastectomy radiation therapy in high-risk premenopausal breast cancer patientsJason H Lee
Department of Radiation Oncology, Division of General Internal Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA
J Clin Oncol 20:2713-25. 2002..To present a decision model that describes the clinical and economic outcomes of node-positive breast cancer with and without postmastectomy radiation therapy (PMRT)... - Treatment recommendations for locally advanced, non-small-cell lung cancer: the influence of physician and patient factorsIrwin H Lee
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 74:1376-84. 2009..To determine the impact of patient age, comorbidity, and physician factors on treatment recommendations for locally advanced, unresectable non-small-cell lung cancer (NSCLC)... - Unacceptable cosmesis in a protocol investigating intensity-modulated radiotherapy with active breathing control for accelerated partial-breast irradiationReshma Jagsi
Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109 5010, USA
Int J Radiat Oncol Biol Phys 76:71-8. 2010..To report interim cosmetic results and toxicity from a prospective study evaluating accelerated partial-breast irradiation (APBI) administered using a highly conformal external beam approach... - Accelerated partial breast irradiation: what is dosimetric effect of advanced technology approaches?Jean M Moran
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 75:294-301. 2009..g., free breathing [FB] and deep inspiration breath hold [DIBH])... - Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): predictors for radiation pneumonitis and fibrosisFeng Ming Kong
Department of Radiation Oncology, University of Michigan, and Radiation Oncology, Veterans Administration Medical Center, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 65:1075-86. 2006.... - Long-term results of high-dose conformal radiotherapy for patients with medically inoperable T1-3N0 non-small-cell lung cancer: is low incidence of regional failure due to incidental nodal irradiation?Ming Chen
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 64:120-6. 2006..To report the results of high-dose conformal irradiation and examine incidental nodal irradiation and nodal failure in patients with inoperable early-stage non-small-cell lung cancer (NSCLC)... - Features predicting sentinel lymph node positivity in Merkel cell carcinomaJennifer L Schwartz
University of Michigan Health System, 1910 Taubman Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 0314, USA
J Clin Oncol 29:1036-41. 2011..Merkel cell carcinoma (MCC) is a relatively rare, potentially aggressive cutaneous malignancy. We examined the clinical and histologic features of primary MCC that may correlate with the probability of a positive sentinel lymph node (SLN)... - Cost-effectiveness of radiation therapy following conservative surgery for ductal carcinoma in situ of the breastW Warren Suh
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 61:1054-61. 2005..To assess the cost-effectiveness of radiation therapy (RT) in patients with ductal carcinoma in situ (DCIS) after breast-conserving surgery (BCS)... - Recent advances in radiation oncologyCharlie C Pan
Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
J Neuroophthalmol 24:251-7. 2004..A good understanding of what can be achieved with modern radiotherapy is important in ensuring an effective multidisciplinary approach to the management of cancer and other benign, yet rapidly proliferating, lesions... - A cost comparison analysis of partial versus whole-breast irradiation after breast-conserving surgery for early-stage breast cancerW Warren Suh
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 62:790-6. 2005..To assess, if and for whom, there are cost savings associated with alternate breast radiotherapy (RT) techniques when compared with the conventional external beam-based whole-breast RT with a boost (WBRT-B)... - Evaluation of the influence of breathing on the movement and modeling of lung tumorsAaron M Allen
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Int J Radiat Oncol Biol Phys 58:1251-7. 2004..This study was designed to evaluate the influence of breathing movement on tumors and to assess the validity of the free-breathing CT scan for target delineation in the lung... - Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinomaSusan G Urba
Division of Hematology Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USA
Cancer 98:2177-83. 2003..A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal carcinoma... - Conservative surgery and radiotherapy for stage I/II breast cancer using lung density correction: 10-year and 15-year resultsLori J Pierce
Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 61:1317-27. 2005..Since 1984, we have used lung density correction for dose calculations at the University of Michigan. We now present our 10-year and 15-year results... - High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation studyFeng Ming Kong
Department of Radiation Oncology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 63:324-33. 2005..To determine whether high-dose radiation leads to improved outcomes in patients with non-small-cell lung cancer (NSCLC)... - Out-of-pocket health-care expenditures among older Americans with cancerKenneth M Langa
Division of General Medicine Department of Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Value Health 7:186-94. 2004.... - Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancerMary Feng
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
Int J Radiat Oncol Biol Phys 79:10-8. 2011..Here we have developed a heart atlas and evaluated its effect on contour accuracy and concordance... - Prospective quality-of-life assessment in patients receiving concurrent gemcitabine and radiotherapy as a bladder preservation strategyJoseph M Herman
Department ofRadiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
Urology 64:69-73. 2004..The results of this study suggest that concurrent gemcitabine with conformal RT is a tolerable treatment regimen for bladder preservation, as demonstrated by the excellent treatment compliance and similar FACT measurements... - Ophthalmic artery occlusion secondary to radiation-induced vasculopathyRita Singh
Department of Ophthalmology, Kellogg Eye Center, University of Michigan Medical Center, 1000 Wall Street, Ann Arbor, MI 48105, USA
J Neuroophthalmol 24:206-10. 2004..Even though modern radiation techniques limit collateral damage, this modality should be used with discretion in NF1 patients, given the vulnerability of their immature cerebral vasculature to radiation... - The treatment planning of segmental, conformal stereotactic radiosurgery utilizing a standard multileaf collimatorP G Archer
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor 48109, USA
Med Dosim 24:13-9. 1999.... - CT-based definition of thoracic lymph node stations: an atlas from the University of MichiganOlivier Chapet
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 63:170-8. 2005..Studies are ongoing at the University of Michigan to measure quantitatively the incidental nodal radiation received by patients with non-small-cell lung cancer... - Comparing the costs of radiation therapy and radical prostatectomy for the initial treatment of early-stage prostate cancerJeffrey H Burkhardt
Research Department, American College of Radiology, Reston, VA, USA
J Clin Oncol 20:2869-75. 2002..This study compares the direct medical costs during the month before and 9 months after diagnosis for patients treated primarily with external-beam radiation or radical prostatectomy for early-stage prostate cancer... - Comparing different NTCP models that predict the incidence of radiation pneumonitis. Normal tissue complication probabilityYvette Seppenwoolde
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 55:724-35. 2003..Thus, for the studied patient population, the MLD was the most accurate predictor for the incidence of radiation pneumonitis... - The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant gliomaMay N Tsao
The American Society for Therapeutic Radiology and Oncology, Fairfax, VA 22033, USA
Int J Radiat Oncol Biol Phys 63:47-55. 2005..There is also insufficient evidence regarding the benefits/harms in the use of stereotactic fractionated radiation therapy for patients with newly diagnosed or progressive/recurrent malignant glioma... - American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancerGary H Lyman
University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
J Clin Oncol 23:7703-20. 2005..To develop a guideline for the use of sentinel node biopsy (SNB) in early stage breast cancer... - Gastric Cancer Clinical Practice GuidelinesJaffer Ajani
J Natl Compr Canc Netw 4:350-66. 2006 - Esophageal Cancer Clinical Practice GuidelinesJaffer Ajani
J Natl Compr Canc Netw 4:328-47. 2006 - The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastasesMinesh P Mehta
The American Society for Therapeutic Radiology and Oncology, Fairfax, VA 22033, USA
Int J Radiat Oncol Biol Phys 63:37-46. 2005..There is insufficient evidence as to the clinical benefit/risks radiosurgery used in the setting of recurrent or progressive brain metastases, although radiographic responses are well-documented... - Second primary cancers after enrollment in the COMS trials for treatment of choroidal melanoma: COMS Report No. 25Marie Diener-West
COMS Coordinating Center, Wilmer Clinical Trials and Biometry, 550 N Broadway, Ninth Floor, Baltimore, MD 21205, USA
Arch Ophthalmol 123:601-4. 2005..To report sites of second primary cancer and the time to first diagnosis during routine follow-up after treatment for choroidal melanoma... - Development of metastatic disease after enrollment in the COMS trials for treatment of choroidal melanoma: Collaborative Ocular Melanoma Study Group Report No. 26Marie Diener-West
Coordinating Center, Wilmer Clinical Trials and Biometry, 550 N Broadway, Ninth Floor, Baltimore, MD 21205, USA
Arch Ophthalmol 123:1639-43. 2005..To describe the time between treatment for choroidal melanoma and first diagnosis of metastatic disease, sites of metastasis, treatments for metastasis, and time between diagnosis of metastasis and death... - Development and validation of disease-specific measures for choroidal melanoma: COMS-QOLS report No. 2Michele Melia
Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, MD 21205 2010, USA
Arch Ophthalmol 121:1010-20. 2003..To develop and validate scales measuring common concerns of patients with choroidal melanoma: perception of appearance, concern about cancer recurrence, and difficulty with vision-dependent activities requiring stereopsis or binocularity...
Research Grants
- Use of Radiation in Stage IV Non-Small Cell Lung CancerJames Hayman; Fiscal Year: 2003..Lastly, we plan to examine whether the frequency and intensity of the administration of treatment with palliative radiation in this patient population has changed over time. ..