Tyrone B Hayes

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Environ Health Perspect 115:720-7. 2007
  2. pmc Diversifying the biological sciences: past efforts and future challenges
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Molecular Toxicology, Group in Endocrinology, Energy and Resources Group, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Mol Biol Cell 21:3767-9. 2010
  3. pmc Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 107:4612-7. 2010
  4. pmc The cause of global amphibian declines: a developmental endocrinologist's perspective
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    J Exp Biol 213:921-33. 2010
  5. doi request reprint Demasculinization and feminization of male gonads by atrazine: consistent effects across vertebrate classes
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Molecular Toxicology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    J Steroid Biochem Mol Biol 127:64-73. 2011
  6. pmc Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/f
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:134-41. 2006
  7. pmc Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:40-50. 2006
  8. ncbi request reprint Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 355:1012-8. 2007
  9. pmc Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 99:5476-80. 2002
  10. ncbi request reprint Variation in thyroid hormone action and tissue content underlies species differences in the timing of metamorphosis in desert frogs
    Daniel R Buchholz
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, Department of Integrative Biology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    Evol Dev 7:458-67. 2005

Collaborators

Detail Information

Publications10

  1. pmc Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Environ Health Perspect 115:720-7. 2007
    ..Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP...
  2. pmc Diversifying the biological sciences: past efforts and future challenges
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Molecular Toxicology, Group in Endocrinology, Energy and Resources Group, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Mol Biol Cell 21:3767-9. 2010
    ..It is imperative that we increase our efforts to prepare for the unique challenges that we will face as the United States approaches a "majority minority" population in the next 50 years...
  3. pmc Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 107:4612-7. 2010
    ..These data are consistent with effects of atrazine observed in other vertebrate classes. The present findings exemplify the role that atrazine and other endocrine-disrupting pesticides likely play in global amphibian declines...
  4. pmc The cause of global amphibian declines: a developmental endocrinologist's perspective
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    J Exp Biol 213:921-33. 2010
    ..Increased attention to recruitment and ultimate factors that interact with pathogens is important in addressing this global crisis...
  5. doi request reprint Demasculinization and feminization of male gonads by atrazine: consistent effects across vertebrate classes
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Molecular Toxicology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    J Steroid Biochem Mol Biol 127:64-73. 2011
    ..Thus the case for atrazine as an endocrine disruptor that demasculinizes and feminizes male vertebrates meets all nine of the "Hill criteria"...
  6. pmc Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/f
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:134-41. 2006
    ....
  7. pmc Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:40-50. 2006
    ....
  8. ncbi request reprint Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 355:1012-8. 2007
    ..These data suggest that atrazine binds to and activates SF-1 to induce ArPII...
  9. pmc Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 99:5476-80. 2002
    ..This widespread compound and other environmental endocrine disruptors may be a factor in global amphibian declines...
  10. ncbi request reprint Variation in thyroid hormone action and tissue content underlies species differences in the timing of metamorphosis in desert frogs
    Daniel R Buchholz
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, Department of Integrative Biology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    Evol Dev 7:458-67. 2005
    ....