T B Hayes

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Sex determination and primary sex differentiation in amphibians: genetic and developmental mechanisms
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, Berkeley, California, USA
    J Exp Zool 281:373-99. 1998
  2. pmc Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 99:5476-80. 2002
  3. ncbi request reprint Herbicides: feminization of male frogs in the wild
    Tyrone Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Nature 419:895-6. 2002
  4. pmc The cause of global amphibian declines: a developmental endocrinologist's perspective
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    J Exp Biol 213:921-33. 2010
  5. ncbi request reprint DDT congener effects on secondary sex coloration in the reed frog Hyperolius argus: a partial evaluation of the Hyperolius argus endocrine screen
    N C Noriega
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Deptartment of Integrative Biology, Museum of Vertebrate Zoology, University of California, Berkeley 94720 3104, USA
    Comp Biochem Physiol B Biochem Mol Biol 126:231-7. 2000
  6. pmc Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence
    Tyrone Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, California 94720, USA
    Environ Health Perspect 111:568-75. 2003
  7. pmc Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:40-50. 2006
  8. pmc Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/f
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:134-41. 2006
  9. ncbi request reprint Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 355:1012-8. 2007
  10. pmc Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Environ Health Perspect 115:720-7. 2007

Research Grants

Collaborators

  • Ryoichi Takayanagi
  • Daniel R Buchholz
  • WuQiang Fan
  • Hidetaka Morinaga
  • Shigeki Gondo
  • Taijiro Okabe
  • Masatoshi Nomura
  • Hajime Nawata
  • Toshihiko Yanase
  • N C Noriega
  • Tomoko Komatsu
  • Ken ichirou Morohashi

Detail Information

Publications11

  1. ncbi request reprint Sex determination and primary sex differentiation in amphibians: genetic and developmental mechanisms
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, Berkeley, California, USA
    J Exp Zool 281:373-99. 1998
    ..Studies examining links between sex determination and gonadal differentiation are needed. In addition, examinations of variation in steroidal effects on gonadal development in a phylogenetic context are lacking...
  2. pmc Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Natl Acad Sci U S A 99:5476-80. 2002
    ..This widespread compound and other environmental endocrine disruptors may be a factor in global amphibian declines...
  3. ncbi request reprint Herbicides: feminization of male frogs in the wild
    Tyrone Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Nature 419:895-6. 2002
  4. pmc The cause of global amphibian declines: a developmental endocrinologist's perspective
    T B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    J Exp Biol 213:921-33. 2010
    ..Increased attention to recruitment and ultimate factors that interact with pathogens is important in addressing this global crisis...
  5. ncbi request reprint DDT congener effects on secondary sex coloration in the reed frog Hyperolius argus: a partial evaluation of the Hyperolius argus endocrine screen
    N C Noriega
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Deptartment of Integrative Biology, Museum of Vertebrate Zoology, University of California, Berkeley 94720 3104, USA
    Comp Biochem Physiol B Biochem Mol Biol 126:231-7. 2000
    ..Estradiol, o,p.DDT (0.1 microg/ml), o,p'DDE (1 microg/ml) and o,p'DDD (1 microg/ml) prematurely induced adult female coloration patterns in juvenile animals, whereas p,p'DDT, p, p'DDE and p,p'DDD did not...
  6. pmc Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence
    Tyrone Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, California 94720, USA
    Environ Health Perspect 111:568-75. 2003
    ....
  7. pmc Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Department of Integrative Biology, Museum of Vertebrate Zoology, Group in Endocrinology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:40-50. 2006
    ....
  8. pmc Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/f
    Tyrone B Hayes
    Laboratory for Integrative Studies in Amphibian Biology, Group in Endocrinology, Museum of Vertebrate Zoology, Department of Integrative Biology, University of California, Berkeley, California 94720 3140, USA
    Environ Health Perspect 114:134-41. 2006
    ....
  9. ncbi request reprint Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 355:1012-8. 2007
    ..These data suggest that atrazine binds to and activates SF-1 to induce ArPII...
  10. pmc Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans
    WuQiang Fan
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Environ Health Perspect 115:720-7. 2007
    ..Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP...
  11. ncbi request reprint Variation in thyroid hormone action and tissue content underlies species differences in the timing of metamorphosis in desert frogs
    Daniel R Buchholz
    Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, Department of Integrative Biology, Group in Endocrinology, University of California, Berkeley, CA 94720 3140, USA
    Evol Dev 7:458-67. 2005
    ....

Research Grants1

  1. ATRAZINE: IMPACT ON ENVIRONMENTAL AND PUBLIC HEALTH
    Tyrone Hayes; Fiscal Year: 2004
    ..abstract_text> ..