LOUISE HAWKLEY

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc The mental representation of social connections: generalizability extended to Beijing adults
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e44065. 2012
  2. pmc Effects of social isolation on glucocorticoid regulation in social mammals
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL, USA
    Horm Behav 62:314-23. 2012
  3. pmc Social regulation of gene expression in human leukocytes
    Steve W Cole
    Department of Medicine, Division of Hematology Oncology, UCLA School of Medicine, Los Angeles, CA 90095 1678, USA
    Genome Biol 8:R189. 2007
  4. ncbi request reprint Loneliness is a unique predictor of age-related differences in systolic blood pressure
    Louise C Hawkley
    Chicago Center for Cognitive and Social Neuroscience, and Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
    Psychol Aging 21:152-64. 2006
  5. pmc Loneliness impairs daytime functioning but not sleep duration
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Health Psychol 29:124-9. 2010
  6. pmc Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults
    Louise C Hawkley
    Department of Psychology, University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA
    Psychol Aging 25:132-41. 2010
  7. pmc Responses to ostracism across adulthood
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Soc Cogn Affect Neurosci 6:234-43. 2011
  8. ncbi request reprint How can I connect with thee? Let me count the ways
    Louise C Hawkley
    Institute for Mind and Biology, The University of Chicago, IL 60637, USA
    Psychol Sci 16:798-804. 2005
  9. pmc From social structural factors to perceptions of relationship quality and loneliness: the Chicago health, aging, and social relations study
    Louise C Hawkley
    Department of Psychology, University of Chicago, Biopsychological Sciences Building, 940 East 57th Street, Chicago, IL 60637, USA
    J Gerontol B Psychol Sci Soc Sci 63:S375-84. 2008
  10. ncbi request reprint Stress and the aging immune system
    Louise C Hawkley
    Institute for Mind and Biology, The University of Chicago, 940 E 57th Street, Chicago, IL 60637, USA
    Brain Behav Immun 18:114-9. 2004

Research Grants

  1. Chicago Endothelial Function Study
    LOUISE HAWKLEY; Fiscal Year: 2009
  2. Chicago Endothelial Function Study
    Louise C Hawkley; Fiscal Year: 2010

Detail Information

Publications40

  1. pmc The mental representation of social connections: generalizability extended to Beijing adults
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e44065. 2012
    ..Equivalence of the three-dimensional structure is relevant for an understanding of cultural differences in the sources of loneliness and social connectedness...
  2. pmc Effects of social isolation on glucocorticoid regulation in social mammals
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL, USA
    Horm Behav 62:314-23. 2012
    ..An animal model of human isolation must be taken more seriously if we want to advance our understanding of the mechanisms for the effects of objective and perceived isolation in humans...
  3. pmc Social regulation of gene expression in human leukocytes
    Steve W Cole
    Department of Medicine, Division of Hematology Oncology, UCLA School of Medicine, Los Angeles, CA 90095 1678, USA
    Genome Biol 8:R189. 2007
    ....
  4. ncbi request reprint Loneliness is a unique predictor of age-related differences in systolic blood pressure
    Louise C Hawkley
    Chicago Center for Cognitive and Social Neuroscience, and Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
    Psychol Aging 21:152-64. 2006
    ..Although the results are limited by the cross-sectional methods used, they are consistent with the hypothesis that cardiovascular disease contributes to increased morbidity and mortality among lonely individuals...
  5. pmc Loneliness impairs daytime functioning but not sleep duration
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Health Psychol 29:124-9. 2010
    ..To assess the prospective association between daily feelings of loneliness and subsequent feelings of daytime dysfunction indicative of poor sleep quality...
  6. pmc Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults
    Louise C Hawkley
    Department of Psychology, University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA
    Psychol Aging 25:132-41. 2010
    ..The effect of loneliness on SBP was independent of age, gender, race or ethnicity, cardiovascular risk factors, medications, health conditions, and the effects of depressive symptoms, social support, perceived stress, and hostility...
  7. pmc Responses to ostracism across adulthood
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Soc Cogn Affect Neurosci 6:234-43. 2011
    ....
  8. ncbi request reprint How can I connect with thee? Let me count the ways
    Louise C Hawkley
    Institute for Mind and Biology, The University of Chicago, IL 60637, USA
    Psychol Sci 16:798-804. 2005
    ..Each facet was uniquely predicted by theoretically related social circumstances. These findings suggest how humans make meaning of their social relationships in their mental representations of loneliness and connectedness...
  9. pmc From social structural factors to perceptions of relationship quality and loneliness: the Chicago health, aging, and social relations study
    Louise C Hawkley
    Department of Psychology, University of Chicago, Biopsychological Sciences Building, 940 East 57th Street, Chicago, IL 60637, USA
    J Gerontol B Psychol Sci Soc Sci 63:S375-84. 2008
    ..The objective of this study was to test a conceptual model of loneliness in which social structural factors are posited to operate through proximal factors to influence perceptions of relationship quality and loneliness...
  10. ncbi request reprint Stress and the aging immune system
    Louise C Hawkley
    Institute for Mind and Biology, The University of Chicago, 940 E 57th Street, Chicago, IL 60637, USA
    Brain Behav Immun 18:114-9. 2004
    ..Research on stress in older adults provides evidence that these processes contribute to effects that mimic, exacerbate, and possibly accelerate the effects of aging on immunity...
  11. pmc Loneliness matters: a theoretical and empirical review of consequences and mechanisms
    Louise C Hawkley
    Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL, USA
    Ann Behav Med 40:218-27. 2010
    ..Loneliness is not simply being alone. Interventions to reduce loneliness and its health consequences may need to take into account its attentional, confirmatory, and memorial biases as well as its social and behavioral effects...
  12. pmc Mediators of the relationship between socioeconomic status and allostatic load in the Chicago Health, Aging, and Social Relations Study (CHASRS)
    Louise C Hawkley
    Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, Illinois, USA
    Psychophysiology 48:1134-45. 2011
    ..SES was significantly associated with two AL components, suggesting that the effects of SES on physiological dysregulation are specific to certain systems in a middle to early old-age population...
  13. ncbi request reprint Loneliness in everyday life: cardiovascular activity, psychosocial context, and health behaviors
    Louise C Hawkley
    Department of Psychology, University of Chicago, Illinois 60637, USA
    J Pers Soc Psychol 85:105-20. 2003
    ..Loneliness differences were not mediated by depressed affect or neuroticism. Social support mediated loneliness differences in stress and threat. Concomitants of loneliness were comparable for men and women...
  14. ncbi request reprint Loneliness and pathways to disease
    Louise C Hawkley
    Institute for Mind and Biology, The University of Chicago, 940 E 57th Street, IL 60637, USA
    Brain Behav Immun 17:S98-105. 2003
    ..For cancer patients, interventions should be aimed at providing instrumental support for the immediate demands of the disease...
  15. ncbi request reprint Cardiovascular and endocrine reactivity in older females: intertask consistency
    L C Hawkley
    Department of Psychology, The Ohio State University, Columbus, USA
    Psychophysiology 38:863-72. 2001
    ..e., response profiles). Further research is recommended to examine the significance of consistent individual differences in response profile...
  16. pmc Loneliness predicts reduced physical activity: cross-sectional & longitudinal analyses
    Louise C Hawkley
    University of Chicago, Chicago, IL 60637, USA
    Health Psychol 28:354-63. 2009
    ..To determine cross-sectional and prospective associations between loneliness and physical activity, and to evaluate the roles of social control and emotion regulation as mediators of these associations...
  17. pmc Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations Study
    John T Cacioppo
    Center for Cognitive and Social Neuroscience, University of Chicago, IL 60637, USA
    Psychol Aging 25:453-63. 2010
    ..The importance of distinguishing between loneliness and depressive symptoms and the implications for loneliness and depressive symptomatology in older adults are discussed...
  18. doi request reprint Perceived social isolation moderates the relationship between early childhood trauma and pulse pressure in older adults
    Greg J Norman
    Department of Psychology, The University of Chicago, Chicago, IL 60637, USA
    Int J Psychophysiol 88:334-8. 2013
    ..Therefore, the detrimental effects of early trauma may be partially dependent upon the quality of social relationships as an adult...
  19. pmc Spirituality and autonomic cardiac control
    Gary G Berntson
    Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
    Ann Behav Med 35:198-208. 2008
    ..Spirituality has been suggested to be associated with positive health, but potential biological mediators have not been well characterized...
  20. pmc Cardiac autonomic balance versus cardiac regulatory capacity
    Gary G Berntson
    Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
    Psychophysiology 45:643-52. 2008
    ..Results reveal that CAR, but not CAB, was a significant predictor of the prior occurrence of a myocardial infarction, net of demographic and other variables, whereas CAB, but not CAR, was a significant predictor of concurrent diabetes...
  21. doi request reprint Variation in the oxytocin receptor gene influences neurocardiac reactivity to social stress and HPA function: a population based study
    Greg J Norman
    Department of Psychology, The University of Chicago, Chicago, IL 60637, USA
    Horm Behav 61:134-9. 2012
    ..Furthermore, analysis of diurnal fluctuations in salivary cortisol revealed that G/G participants displayed lower awakening cortisol levels and less variation in salivary cortisol across the day as compared to A carrier individuals...
  22. ncbi request reprint Loneliness as a specific risk factor for depressive symptoms: cross-sectional and longitudinal analyses
    John T Cacioppo
    Center for Cognitive and Social Neuroscience, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
    Psychol Aging 21:140-51. 2006
    ..These data suggest that loneliness and depressive symptomatology can act in a synergistic effect to diminish well-being in middle-aged and older adults...
  23. ncbi request reprint Estrogen metabolites and systolic blood pressure in a population-based sample of postmenopausal women
    Christopher M Masi
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Endocrinol Metab 91:1015-20. 2006
    ..Concentrations of 2-hydroxyestrone (2-OHE) and 16alpha-hydroxyestrone (16-OHE) in urine reflect the relative activity of the 2- and 16alpha-hydroxylation pathways of 17beta-estradiol...
  24. ncbi request reprint Gender and ethnic differences in urinary stress hormones: the population-based Chicago Health, Aging, and Social Relations Study
    Christopher M Masi
    Institute for Mind and Biology, University of Chicago, Chicago, Illinois 60637, USA
    J Appl Physiol (1985) 97:941-7. 2004
    ..The consistency of these results with previous studies of 24-h urine samples suggests muscle mass should be accounted for when comparing overnight urinary hormone values across gender and ethnicity...
  25. ncbi request reprint Loneliness and health: potential mechanisms
    John T Cacioppo
    Department of Psychology, University of Chicago, Chicago, IL 60637, USA
    Psychosom Med 64:407-17. 2002
    ..Two studies using cross-sectional designs explored four possible mechanisms by which loneliness may have deleterious effects on health: health behaviors, cardiovascular activation, cortisol levels, and sleep...
  26. ncbi request reprint Social isolation and health, with an emphasis on underlying mechanisms
    John T Cacioppo
    Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
    Perspect Biol Med 46:S39-52. 2003
    ..We advocate a national health care plan that promotes preventive medicine, recognizes the significance of stress-related disorders, and supports the maintenance of social connections across the life span...
  27. ncbi request reprint Do lonely days invade the nights? Potential social modulation of sleep efficiency
    John T Cacioppo
    Department of Psychology, University of Chicago, IL 60637, USA
    Psychol Sci 13:384-7. 2002
    ..These results also raise the possibility that social factors such as loneliness not only may influence the selection of health behaviors but also may modulate the salubrity of restorative behaviors...
  28. pmc Job insecurity and change over time in health among older men and women
    Ariel Kalil
    University of Chicago, IL 60637, USA
    J Gerontol B Psychol Sci Soc Sci 65:81-90. 2010
    ..We estimated associations between job insecurity and change over time in the physical and psychological health of older adult men and women...
  29. pmc Perceived social isolation and cognition
    John T Cacioppo
    Center for Cognitive and Social Neuroscience, University of Chicago, 5848 S University Avenue, Chicago, IL 60637, USA
    Trends Cogn Sci 13:447-54. 2009
    ....
  30. pmc Serum estrogen metabolites and systolic blood pressure among middle-aged and older women and men
    Christopher M Masi
    Section of General Internal Medicine and the Department of Medicine, University of Chicago, IL, USA
    Am J Hypertens 22:1148-53. 2009
    ..We tested whether serum 17beta-estradiol (E(2)) or any of its metabolites were associated with SBP among middle-aged and older adults...
  31. ncbi request reprint Neighborhood economic disadvantage, violent crime, group density, and pregnancy outcomes in a diverse, urban population
    Christopher M Masi
    University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Soc Sci Med 65:2440-57. 2007
    ..These results suggest that group density and violent crime may impact birth weight via different mechanisms...
  32. pmc Respiratory sinus arrhythmia and diseases of aging: obesity, diabetes mellitus, and hypertension
    Christopher M Masi
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Biol Psychol 74:212-23. 2007
    ..We conclude that the relationship between RSA and hypertension is somewhat independent of the age-related decline in parasympathetic activity...
  33. pmc Autonomic tone and C-reactive protein: a prospective population-based study
    Puneet Singh
    University of Chicago Pritzker School of Medicine, IL, USA
    Clin Auton Res 19:367-74. 2009
    ..To examine the cross-sectional and longitudinal relationships between cardiac autonomic tone and serum CRP and to investigate potential causal links between these measures...
  34. ncbi request reprint Stress-related immune changes in middle-aged and older women: 1-year consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix 85069 7100, USA
    Health Psychol 21:321-31. 2002
    ..Results support longitudinal study of psychosocial context effects on tonic immune function and posttask scores...
  35. ncbi request reprint Compliance with ambulatory saliva sampling in the chicago health, aging, and social relations study and associations with social support
    Brigitte M Kudielka
    Graduate School of Psychobiology, University of Trier, Trier, Germany
    Ann Behav Med 34:209-16. 2007
    ..Noncompliance with instructed saliva sampling times in ambulatory settings can compromise resulting cortisol findings...
  36. ncbi request reprint Objective and perceived neighborhood environment, individual SES and psychosocial factors, and self-rated health: an analysis of older adults in Cook County, Illinois
    Ming Wen
    Department of Sociology, University of Utah, Salt Lake City, UT 84112 0250, USA
    Soc Sci Med 63:2575-90. 2006
    ..In sum, the research supports a model in which the effects of neighborhood SES on self-rated health act through sequential pathways of individual SES, perceptions of neighborhood quality, and psychosocial status...
  37. ncbi request reprint Psychosocial and behavioral predictors of inflammation in middle-aged and older adults: the Chicago health, aging, and social relations study
    Thomas W McDade
    Department of Anthropology, Northwestern University, 1810 Hinman Avenue, Evanston, Illinois 60208 1310, USA
    Psychosom Med 68:376-81. 2006
    ..We investigated the contribution of behavioral and psychosocial factors to variation in CRP concentrations in a population-based sample of middle-aged and older adults...
  38. ncbi request reprint Neuroendocrine and cardiovascular reactivity to stress in mid-aged and older women: long-term temporal consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix, Arizona 85069, USA
    Psychophysiology 40:358-69. 2003
    ..65); consistency for other variables was moderate to low (rs approximately equal to .1-.4). Means of most variables changed from year to year. Results support the use of baseline, stressor, and posttask values in longitudinal studies...
  39. ncbi request reprint Genetic and environmental contributions to loneliness in adults: the Netherlands twin register study
    Dorret I Boomsma
    Vrije Universiteit, Van der Boechorststraat 1, 1081 Amsterdam, BT, The Netherlands
    Behav Genet 35:745-52. 2005
    ..All resemblance between twin relatives was explained by shared genes, without any suggestion of a contribution of shared environmental factors...
  40. pmc Day-to-day dynamics of experience--cortisol associations in a population-based sample of older adults
    Emma K Adam
    School of Education and Social Policy and Cells to Society Center, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
    Proc Natl Acad Sci U S A 103:17058-63. 2006
    ..Results are consistent with a dynamic and transactional function of cortisol as both a transducer of psychosocial and emotional experience into physiological activation and an influence on feelings of energy and physical well-being...

Research Grants2

  1. Chicago Endothelial Function Study
    LOUISE HAWKLEY; Fiscal Year: 2009
    ..11/07) Page. Form Page 4 ..
  2. Chicago Endothelial Function Study
    Louise C Hawkley; Fiscal Year: 2010
    ..11/07) Page. Form Page 4 ..