Dominik R Haudenschild

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Rho kinase-dependent activation of SOX9 in chondrocytes
    Dominik R Haudenschild
    The Scripps Research Institute, La Jolla, California, USA
    Arthritis Rheum 62:191-200. 2010
  2. ncbi Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis
    Dominik R Haudenschild
    Shiley Center for Orthopaedic Research and Education at Scripps Clinic, 11025 North Torrey Pines Road, La Jolla, California 92037, USA
    J Orthop Res 29:20-5. 2011
  3. ncbi Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein
    Dominik R Haudenschild
    Lawrence J Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California 95817, USA
    J Biol Chem 286:43250-8. 2011
  4. ncbi Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes
    Dominik R Haudenschild
    Scripps Research Institute, and Scripps Clinic, La Jolla, California 92037, USA
    Arthritis Rheum 58:2735-42. 2008
  5. ncbi Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene
    Derek F Amanatullah
    Department of Orthopaedic Surgery, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Tissue Eng Part A 18:1882-9. 2012
  6. ncbi Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA
    Dominik R Haudenschild
    Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Sacramento, California 95817, USA
    Prostate 66:1268-74. 2006
  7. ncbi Immunolocalization of IL-17A, IL-17B, and their receptors in chondrocytes during fracture healing
    Takeshi Kokubu
    Center for Tissue Regeneration and Repair, Department of Orthopedics, University of California, School of Medicine, 4635 Second Avenue, Sacramento, CA 95817, USA
    J Histochem Cytochem 56:89-95. 2008
  8. ncbi Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer
    Dominik R Haudenschild
    Center for Tissue Regeneration and Repair, Department of Orthopedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
    Cancer Res 64:8276-84. 2004
  9. ncbi The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance
    Ratna Kumari
    Department of Orthopaedic Surgery, Lawrence J Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Carcinogenesis 33:2076-83. 2012

Collaborators

Detail Information

Publications9

  1. ncbi Rho kinase-dependent activation of SOX9 in chondrocytes
    Dominik R Haudenschild
    The Scripps Research Institute, La Jolla, California, USA
    Arthritis Rheum 62:191-200. 2010
    ..However, the mechanisms linking ROCK to altered chondrocyte gene expression remain unknown. The purpose of the present study was to test for a direct interaction between ROCK and SOX9...
  2. ncbi Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis
    Dominik R Haudenschild
    Shiley Center for Orthopaedic Research and Education at Scripps Clinic, 11025 North Torrey Pines Road, La Jolla, California 92037, USA
    J Orthop Res 29:20-5. 2011
    ..This 3D experimental system revealed contributions of vimentin to chondrocyte stiffness previously not apparent, and correlated changes in vimentin-based chondrocyte stiffness with osteoarthritis...
  3. ncbi Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein
    Dominik R Haudenschild
    Lawrence J Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California 95817, USA
    J Biol Chem 286:43250-8. 2011
    ..Finally, we show that COMP-bound TGF-β1 causes increased TGF-β1-dependent transcription. We conclude that TGF-β1 binds to COMP and that TGF-β1 bound to COMP has enhanced bioactivity...
  4. ncbi Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes
    Dominik R Haudenschild
    Scripps Research Institute, and Scripps Clinic, La Jolla, California 92037, USA
    Arthritis Rheum 58:2735-42. 2008
    ..Reorganization of the actin cytoskeleton results from Rho GTPase activation. The purpose of this study was to examine the roles of both actin and Rho in mechanotransduction in chondrocytes...
  5. ncbi Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene
    Derek F Amanatullah
    Department of Orthopaedic Surgery, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Tissue Eng Part A 18:1882-9. 2012
    ..This information is critical to understanding how mechanical force regulates the transcriptional activation of cartilage genes in three-dimensional culture...
  6. ncbi Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA
    Dominik R Haudenschild
    Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Sacramento, California 95817, USA
    Prostate 66:1268-74. 2006
    ..Predominant IL-17RL splice isoform variants have not been identified, hindering functional studies...
  7. ncbi Immunolocalization of IL-17A, IL-17B, and their receptors in chondrocytes during fracture healing
    Takeshi Kokubu
    Center for Tissue Regeneration and Repair, Department of Orthopedics, University of California, School of Medicine, 4635 Second Avenue, Sacramento, CA 95817, USA
    J Histochem Cytochem 56:89-95. 2008
    ..Moreover, we found significant parallels to the localization of these cytokines and their receptors in chondrocytes during an endochondral differentiation program in the epiphyseal growth plate...
  8. ncbi Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer
    Dominik R Haudenschild
    Center for Tissue Regeneration and Repair, Department of Orthopedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
    Cancer Res 64:8276-84. 2004
    ....
  9. ncbi The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance
    Ratna Kumari
    Department of Orthopaedic Surgery, Lawrence J Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Carcinogenesis 33:2076-83. 2012
    ..Our data implicate the potential role of LRF as both a diagnostic marker and therapeutic target for chondrosarcomas...