Research Topics
Species | GLENN HATTONSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Neurophysiology of magnocellular neuroendocrine cells: recent advancesG I Hatton
Department of Neuroscience, University of California, Riverside 92521, USA
Prog Brain Res 119:77-99. 1998....- Dynamic neuronal-glial interactions: an overview 20 years laterGlenn I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
Peptides 25:403-11. 2004..quot; The final section is an update and brief overview of highlights of both "what we know now" and "what we now know that we don't know" about dynamic neuronal-astroglial interactions in the mHNS... - Glial-neuronal interactions in the mammalian brainGlenn I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
Adv Physiol Educ 26:225-37. 2002.... - Peripartum interneuronal coupling in the supraoptic nucleusGlenn I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
Brain Res 932:120-3. 2002..It is suggested that gj conductance states, but not gj expression, are modulated by plasma estradiol titers... - Ionotropic histamine receptors and H2 receptors modulate supraoptic oxytocin neuronal excitability and dye couplingG I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurosci 21:2974-82. 2001..These results suggest that synaptically released histamine, in addition to evoking fast IPSPs in OX cells, mediates a prolonged decrease in excitability and uncoupling of the neurons... - Synaptic potentials mediated by alpha 7 nicotinic acetylcholine receptors in supraoptic nucleusGlenn I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurosci 22:29-37. 2002..This is the first demonstration that synaptically released ACh results in fast, alpha7 nAChR-mediated EPSPs in hypothalamic neurons... - Milk ejection burst-like electrical activity evoked in supraoptic oxytocin neurons in slices from lactating ratsYu-Feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurophysiol 91:2312-21. 2004..Our extensive analysis of these results suggests that the in vitro burst is a useful model for further study of mechanisms underlying milk-ejection bursts of OT neurons in vivo... - Burst firing of oxytocin neurons in male rat hypothalamic slicesYu-Feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
Brain Res 1032:36-43. 2005..Thus, we conclude that OT neurons in males are capable of burst firing highly similar to that seen in lactating rats... - Activation of adenosine A2A receptors alters postsynaptic currents and depolarizes neurons of the supraoptic nucleusTodd A Ponzio
Department of Cell Biology and Neuroscience, University of California, Riverside, USA
Am J Physiol Regul Integr Comp Physiol 291:R359-66. 2006..We suggest that adenosine A2A receptors may function in neuroendocrine regulation through both direct neuronal mechanisms and via actions involving glia... - Fractones and other basal laminae in the hypothalamusFrederic Mercier
Department of Cell Biology and Neuroscience, University of California Riverside, Riverside, California 92521, USA
J Comp Neurol 455:324-40. 2003.... - Dominant role of betagamma subunits of G-proteins in oxytocin-evoked burst firingYu feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, Riverside, California 92521, USA
J Neurosci 27:1902-12. 2007..We conclude that G betagamma subunits play a dominant role in burst firing evoked by applied OT or by suckling... - Interaction of extracellular signal-regulated protein kinase 1/2 with actin cytoskeleton in supraoptic oxytocin neurons and astrocytes: role in burst firingYu feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurosci 27:13822-34. 2007..This is the first demonstration that OT mediation of suckling-evoked bursts/milk ejections is via interactions between pERK1/2 and actin cytoskeleton... 
Neural mechanisms underlying the milk ejection burst and reflexGlenn I Hatton
Department of Cell Biology and Neuroscience, University of California, Riverside, CA, USA
Prog Brain Res 170:155-66. 2008..Here we review many of the cellular and molecular mechanisms that have been shown to underlie the milk ejection bursts, as revealed by in vitro analyses...- Mechanisms underlying oxytocin-induced excitation of supraoptic neurons: prostaglandin mediation of actin polymerizationYu feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurophysiol 95:3933-47. 2006..Indomethacin blocked enhancement of F-actin networks by OT but not by PGE2. These results indicate that PGs serve as a common mediator of Galpha(q/11)/GPCR-activating agents in neuronal function... - Autofeedback effects of progressively rising oxytocin concentrations on supraoptic oxytocin neuronal activity in slices from lactating ratsYu feng Wang
Dept of Cell Biology and Neuroscience, Univ of California, Riverside, Riverside, CA 92521, USA
Am J Physiol Regul Integr Comp Physiol 290:R1191-8. 2006..These results suggest that the specific autoregulatory effects of OT, and perhaps other neuropeptides as well, are time and concentration dependent... - Astrocytic plasticity and patterned oxytocin neuronal activity: dynamic interactionsYu feng Wang
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurosci 29:1743-54. 2009..MER also decreased the association between GFAP and glutamine synthetase. These results indicate that suckling elicits dynamic glial neuronal interactions in the SON; GFAP plasticity dynamically reflects OT neuronal activity... - Adenosine postsynaptically modulates supraoptic neuronal excitabilityTodd A Ponzio
Department of Cell Biology and Neuroscience, University of California, Riverside, CA, USA
J Neurophysiol 93:535-47. 2005..It is concluded that adenosine, acting at postsynaptic A(1) receptors, exhibits a powerful inhibitory influence on supraoptic magnocellular activity and is an important endogenous regulator of magnocellular neuroendocrine function... - Histamine H1-receptor modulation of inter-neuronal coupling among vasopressinergic neurons depends on nitric oxide synthase activationQin Zhao Yang
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
Brain Res 955:115-22. 2002..We conclude that H(1)-receptors activate NO synthase via G-protein-coupled pathways and that NO working though its receptor, induces the downstream cGMP-dependent processes that result in increased inter-neuronal coupling... - Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage networkFrederic Mercier
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Comp Neurol 451:170-88. 2002.... - Taurine and the control of basal hormone release from rat neurohypophysisZhilin Song
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
Exp Neurol 183:330-7. 2003..Taurine-induced partial depolarization resulting in Na(+) channel inactivation is probably responsible for its previously observed inhibition of stimulated hormone release from neural lobe... - Activity-related, dynamic neuron-glial interactions in the hypothalamo-neurohypophysial systemSeiji Miyata
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585 Japan
Microsc Res Tech 56:143-57. 2002..Thus, the hypothalamo-neurohypophysial system is an interesting model for elucidating physiological significance and molecular mechanisms of activity-dependent structural plasticity in adult brains... - The puzzle of pulsatile oxytocin secretion during lactation: some new piecesWilliam E Armstrong
Department of Anatomy and Neurobiology, Unversity of Tennessee Medical School, Memphis, Tennessee 38163, USA
Am J Physiol Regul Integr Comp Physiol 291:R26-8. 2006 - Catecholaminergic control of mitogen-activated protein kinase signaling in paraventricular neuroendocrine neurons in vivo and in vitro: a proposed role during glycemic challengesArshad M Khan
Neuroscience Research Institute and Department of Biological Sciences, University of Southern California, Los Angeles, California 90089 2520, USA
J Neurosci 27:7344-60. 2007....
Research Grants
- INTERNAL SENSING SYSTEMS IN HYPOTHALMUSGLENN HATTON; Fiscal Year: 2003..Specific experiments address questions of the cell types involved, their modes of intercellular communication with cells of homotypic and heterotypic nature, and their signaling capacity. ..
- INTERNAL SENSING SYSTEMS IN HYPOTHALAMUSGLENN HATTON; Fiscal Year: 1992..The approaches to be used in these studies include light and electron microscopy, electrophysiology of brain slices and immunocytochemistry. ..
- INTERNAL SENSING SYSTEMS IN HYPOTHALAMUSGLENN HATTON; Fiscal Year: 1993..Plasticity in the somatic and dendritic zones; b. Plasticity in the NL 3. To investigate some of the functional consequence of the morphological changes that are now so well documented in the HNS..
- INTERNAL SENSING SYSTEMS IN HYPOTHALAMUSGLENN HATTON; Fiscal Year: 1999..Plasticity in the somatic and dendritic zones; b. Plasticity in the NL 3. To investigate some of the functional consequence of the morphological changes that are now so well documented in the HNS ..
- INTERNAL SENSING SYSTEMS IN HYPOTHALAMUSGLENN HATTON; Fiscal Year: 2007..stimulated physiological conditions. Also to be examined are the effects on excitability of simultaneously activating two or more of the receptors that are known to be expressed in the SON. ..