PATRICK ANTHONY JOHN HASLETT

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi request reprint Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro
    Patrick A J Haslett
    The Rockefeller University, New York, New York, USA
    J Infect Dis 187:946-55. 2003
  2. ncbi request reprint Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation
    Patrick A J Haslett
    Rockefeller University, New York, New York, USA
    J Infect Dis 192:2045-53. 2005
  3. ncbi request reprint Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells
    Marie Larsson
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY, USA
    AIDS 16:171-80. 2002
  4. ncbi request reprint Mycobacterium tuberculosis inhibits maturation of human monocyte-derived dendritic cells in vitro
    Willem A Hanekom
    Department of Pediatrics, Division of Infectious Disease and Immunology, University of Miami School of Medicine, 1550 NW 10th Avenue, Suite 211 D4 4, Miami, FL 33136, USA
    J Infect Dis 188:257-66. 2003
  5. ncbi request reprint Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies
    Willem A Hanekom
    Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33101, USA
    J Immunol Methods 291:185-95. 2004

Research Grants

  1. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2001
  2. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2003
  3. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2002
  4. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2004
  5. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2005

Detail Information

Publications5

  1. ncbi request reprint Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro
    Patrick A J Haslett
    The Rockefeller University, New York, New York, USA
    J Infect Dis 187:946-55. 2003
    ..This stimulatory effect was directed at CD8(+) T cells, and not DCs. These results suggest an application for thalidomide and the thalidomide analogue as a novel immune-adjuvant therapy in chronic viral infections...
  2. ncbi request reprint Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation
    Patrick A J Haslett
    Rockefeller University, New York, New York, USA
    J Infect Dis 192:2045-53. 2005
    ..Hence, the therapeutic effect of thalidomide in ENL appears to be associated with transient immune stimulation, which suggests that the drug may promote an active immunoregulatory response...
  3. ncbi request reprint Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells
    Marie Larsson
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY, USA
    AIDS 16:171-80. 2002
    ..To utilize the potent antigen-presenting capacity of mature dendritic cells (MDC) in order to develop a rapid, sensitive method for quantifying antigen-specific CD8 T cells present at low frequency in peripheral blood...
  4. ncbi request reprint Mycobacterium tuberculosis inhibits maturation of human monocyte-derived dendritic cells in vitro
    Willem A Hanekom
    Department of Pediatrics, Division of Infectious Disease and Immunology, University of Miami School of Medicine, 1550 NW 10th Avenue, Suite 211 D4 4, Miami, FL 33136, USA
    J Infect Dis 188:257-66. 2003
    ..This mechanism, which has been described elsewhere for various viruses and for the virulent mycobacterium M. leprae, may be a novel mechanism that this pathogen uses to evade the host's immune response...
  5. ncbi request reprint Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies
    Willem A Hanekom
    Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33101, USA
    J Immunol Methods 291:185-95. 2004
    ..The assay proved sensitive and specific for detecting mycobacteria-specific immunity 10 weeks after Bacillus Calmette-Guerin (BCG) vaccination of newborns from a rural field site...

Research Grants5

  1. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2001
    ..If the results support the study hypothesis, a new approach to immune-based therapy for HIV disease will be suggested, as well as a rationale for clinical applications of an oral immune adjuvant drug. ..
  2. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2003
    ..If the results support the study hypothesis, a new approach to immune-based therapy for HIV disease will be suggested, as well as a rationale for clinical applications of an oral immune adjuvant drug. ..
  3. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2002
    ..If the results support the study hypothesis, a new approach to immune-based therapy for HIV disease will be suggested, as well as a rationale for clinical applications of an oral immune adjuvant drug. ..
  4. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2004
    ..If the results support the study hypothesis, a new approach to immune-based therapy for HIV disease will be suggested, as well as a rationale for clinical applications of an oral immune adjuvant drug. ..
  5. PHARMACOLOGIC T CELL COSTIMULATION IN HIV DISEASE
    Patrick Haslett; Fiscal Year: 2005
    ..If the results support the study hypothesis, a new approach to immune-based therapy for HIV disease will be suggested, as well as a rationale for clinical applications of an oral immune adjuvant drug. ..