Research Topics
| Kouichi HasegawaSummaryAffiliation: University of Southern California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusionKouichi Hasegawa
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, University of Southern California, Los Angeles, California 90033, USA
Stem Cells 28:1338-48. 2010..The findings also suggest that the nucleus of the host pluripotent cell may contain components that accelerate the reprogramming process...
Current technology for the derivation of pluripotent stem cell lines from human embryosKouichi Hasegawa
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Cell Stem Cell 6:521-31. 2010..Here, we review the current status of methodology for human embryonic stem cell derivation and culture, and we highlight the challenges that remain for workers in the field...
A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell linesNan Sook Lee
Department of Physiology and Biophysics and Zilkha Neurogenetics Institute, University of Southern California, Los Angeles, California, United States of America
PLoS ONE 7:e35521. 2012..We anticipate its utility for FACS purification of INS(+) and glucose-responsive beta-like-cells from primary human islet cell isolates or in vitro differentiated pluripotent stem cells...
Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansionKouichi Hasegawa
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, California 90033, USA
Stem Cells Transl Med 1:18-28. 2012..This Wnt-dependent culture system should provide a platform for complete replacement of growth factors with chemical compounds...
Klf4 interacts directly with Oct4 and Sox2 to promote reprogrammingZong Wei
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Stem Cells 27:2969-78. 2009..This study supports the idea that direct interactions between Klf4, Oct4, and Sox2 are critical for somatic cell reprogramming...
Simpler and safer cell reprogrammingMartin F Pera
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Nat Biotechnol 26:59-60. 2008
