David Hasan

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Critical role of TNF-α in cerebral aneurysm formation and progression to rupture
    Robert M Starke
    Joseph and Marie Field Cerebrovascular Research Laboratory, Division of Neurovascular and Endovascular Surgery, Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA
    J Neuroinflammation 11:77. 2014
  2. pmc Cerebral blood flow dynamics and head-of-bed changes in the setting of subarachnoid hemorrhage
    David K Kung
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Biomed Res Int 2013:640638. 2013
  3. doi request reprint Imaging aspirin effect on macrophages in the wall of human cerebral aneurysms using ferumoxytol-enhanced MRI: preliminary results
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Neuroradiol 40:187-91. 2013
  4. pmc Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Am Heart Assoc 2:e000019. 2013
  5. pmc Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral aneurysm: a pilot study
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Stroke 43:3258-65. 2012
  6. pmc Macrophage imaging within human cerebral aneurysms wall using ferumoxytol-enhanced MRI: a pilot study
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, USA
    Arterioscler Thromb Vasc Biol 32:1032-8. 2012
  7. pmc Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Stroke 43:1964-7. 2012
  8. pmc Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Neuroinflammation 9:222. 2012
  9. doi request reprint Endovascular treatment of distal intracranial aneurysms with Onyx 18/34
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, USA
    Clin Neurol Neurosurg 115:2528-32. 2013
  10. doi request reprint The Pipeline Embolization Device: learning curve and predictors of complications and aneurysm obliteration
    Pascal Jabbour
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA
    Neurosurgery 73:113-20; discussion 120. 2013

Collaborators

Detail Information

Publications38

  1. pmc Critical role of TNF-α in cerebral aneurysm formation and progression to rupture
    Robert M Starke
    Joseph and Marie Field Cerebrovascular Research Laboratory, Division of Neurovascular and Endovascular Surgery, Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA
    J Neuroinflammation 11:77. 2014
    ..Alterations in TNF-α expression have been associated with cerebral aneurysms, but a direct role in formation, progression, and rupture has not been established...
  2. pmc Cerebral blood flow dynamics and head-of-bed changes in the setting of subarachnoid hemorrhage
    David K Kung
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Biomed Res Int 2013:640638. 2013
    ..Changing HOB position in the setting of SAH did not significantly affect cerebral or regional blood flow. These data suggest that early mobilization should be considered given the detrimental effects of prolonged bed rest...
  3. doi request reprint Imaging aspirin effect on macrophages in the wall of human cerebral aneurysms using ferumoxytol-enhanced MRI: preliminary results
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Neuroradiol 40:187-91. 2013
    ..The goal of the present study is to image aspirin effect on macrophages in the wall of human cerebral aneurysm using ferumoxytol-enhanced MRI...
  4. pmc Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Am Heart Assoc 2:e000019. 2013
    ..The goal of this study was to determine the effects of ASA on inflammatory cells and molecules in the walls of human cerebral aneurysms, using radiographic and histological techniques...
  5. pmc Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral aneurysm: a pilot study
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Stroke 43:3258-65. 2012
    ..The purpose of this study was to determine whether early uptake of ferumoxytol suggests unstable cerebral aneurysm...
  6. pmc Macrophage imaging within human cerebral aneurysms wall using ferumoxytol-enhanced MRI: a pilot study
    David M Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, USA
    Arterioscler Thromb Vasc Biol 32:1032-8. 2012
    ..The purpose of this study is to demonstrate the feasibility and optimal parameters of imaging macrophages within human cerebral aneurysm wall using ferumoxytol-enhanced MRI...
  7. pmc Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, JCP 1616, Iowa City, IA 52242, USA
    Stroke 43:1964-7. 2012
    ..The upregulation of COX-2/mPGES-1 in the wall of ruptured human cerebral aneurysms is not known...
  8. pmc Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results
    David Hasan
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    J Neuroinflammation 9:222. 2012
    ..This study aims to investigate the role of macrophage M1/M2 imbalance and mast cells in the progression of human cerebral aneurysms to rupture...
  9. doi request reprint Endovascular treatment of distal intracranial aneurysms with Onyx 18/34
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, USA
    Clin Neurol Neurosurg 115:2528-32. 2013
    ..The goal of this study was to assess the feasibility, safety and efficacy of treatment of distal aneurysms with the liquid embolic agent Onyx 18/34...
  10. doi request reprint The Pipeline Embolization Device: learning curve and predictors of complications and aneurysm obliteration
    Pascal Jabbour
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA
    Neurosurgery 73:113-20; discussion 120. 2013
    ..The Pipeline Embolization Device (PED) has emerged as a promising treatment for intracranial aneurysms...
  11. doi request reprint Stent-assisted coiling of wide-necked aneurysms in the setting of acute subarachnoid hemorrhage: experience in 65 patients
    Peter S Amenta
    Department of Neurological Surgery, Division of Vascular Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Neurosurgery 70:1415-29; discussion 1429. 2012
    ..Stent-assisted coiling in the setting of subarachnoid hemorrhage remains controversial. Currently, there is a paucity of data regarding the utility of this procedure and the risks of hemorrhagic and ischemic complications...
  12. doi request reprint Extending the indications of flow diversion to small, unruptured, saccular aneurysms of the anterior circulation
    Nohra Chalouhi
    From the Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA N C, R M S, S Y, C D B, S T, L F G, R R, P J and Department of Neurosurgery, University of Iowa, Iowa City, IA D H
    Stroke 45:54-8. 2014
    ..The purpose of this study was to determine whether the indications of flow diversion can be safely extended to unruptured, small, saccular aneurysms (<10 mm) of the anterior circulation...
  13. doi request reprint Flow-diversion for ophthalmic segment aneurysms
    Mario Zanaty
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania Department of Neurosurgery, University of Virginia, Charlottesville, Virginia Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa
    Neurosurgery 76:286-9; discussion 289-90. 2015
    ..The use of flow-diversion to treat ophthalmic segment aneurysms (OSA) has not been well evaluated...
  14. doi request reprint Comparison of flow diversion and coiling in large unruptured intracranial saccular aneurysms
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
    Stroke 44:2150-4. 2013
    ..The purpose of this study was to compare flow diversion and traditional embolization strategies in terms of safety, efficacy, and clinical outcomes in patients with unruptured, large saccular aneurysms (≥10 mm)...
  15. doi request reprint Is packing density important in stent-assisted coiling?
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania 19107, USA
    Neurosurgery 71:381-6; discussion 386-7. 2012
    ....
  16. pmc Update on intra-arterial chemotherapy for retinoblastoma
    Mario Zanaty
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
    ScientificWorldJournal 2014:869604. 2014
    ..Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies. ..
  17. doi request reprint Preoperative spinal tumor embolization: an institutional experience with Onyx
    George M Ghobrial
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, USA
    Clin Neurol Neurosurg 115:2457-63. 2013
    ..Preoperative embolization has the potential to decrease intraoperative blood loss and facilitate spinal cord decompression and tumor resection...
  18. doi request reprint Treatment of ruptured intracranial aneurysms with the pipeline embolization device
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania Department of Neurosurgery, University of Iowa, Iowa City, Iowa
    Neurosurgery 76:165-72; discussion 172. 2015
    ..The pipeline embolization device (PED) has been used for treatment of unruptured aneurysms. Little is known about the use of the PED in ruptured aneurysms...
  19. pmc Endovascular treatment of cerebral mycotic aneurysm: a review of the literature and single center experience
    Mario Zanaty
    Department of Neurosurgery, Thomas Jefferson University, Jefferson Hospital for Neuroscience, Philadelphia, PA, USA
    Biomed Res Int 2013:151643. 2013
    ..This novel solution seems to provide additional benefits and long-term favorable outcomes. ..
  20. doi request reprint Treatment of blister-like aneurysms with the pipeline embolization device
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania Department of Neurosurgery, University of Iowa, Iowa City, Iowa
    Neurosurgery 74:527-32; discussion 532. 2014
    ..Endovascular vessel reconstruction with the pipeline embolization device (PED) has become common practice. Data on the safety and efficacy of the PED in blister-like aneurysms (BLAs) are limited...
  21. doi request reprint Carotid and vertebral artery sacrifice with a combination of Onyx and coils: technical note and case series
    Nohra Chalouhi
    Department of Neurological Surgery, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA
    Neuroradiology 55:993-8. 2013
    ..The purpose of this study is to describe a new technique for carotid and vertebral artery sacrifice using a combination of Onyx and coils and to assess its feasibility, safety, and efficacy...
  22. doi request reprint CT perfusion-guided versus time-guided mechanical recanalization in acute ischemic stroke patients
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, USA
    Clin Neurol Neurosurg 115:2471-5. 2013
    ..We compare the safety and efficacy of CT perfusion (CTP)-guided to time-guided mechanical recanalization in acute ischemic stroke (AIS) patients...
  23. doi request reprint Endovascular stroke intervention in the very young
    Mario Zanaty
    Department of Neurosurgery, Thomas Jefferson University, Philadelphia, USA
    Clin Neurol Neurosurg 127:15-8. 2014
    ..This study aims to evaluate the use of endovascular therapy to treat very young (≤ 35 years) patients with acute ischemic stroke from large vessel occlusion...
  24. doi request reprint Microsurgical clipping of large and giant cerebral aneurysms: a single-center contemporary experience
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, 901 Walnut Street 3rd Floor, Philadelphia, PA 19107, USA
    J Clin Neurosci 21:1424-7. 2014
    ..These data suggest that microsurgical clipping continues to be a viable option that can be offered for patients with large and giant aneurysms...
  25. doi request reprint Safety and efficacy of tirofiban in stent-assisted coil embolization of intracranial aneurysms
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA
    Neurosurgery 71:710-4; discussion 714. 2012
    ..Thromboembolic complications are a major concern in stent-assisted coiling of intracranial aneurysms that may be prevented with adequate antiplatelet therapy...
  26. doi request reprint The emerging role of ferumoxytol-enhanced MRI in the management of cerebrovascular lesions
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
    Molecules 18:9670-83. 2013
    ..In this paper, we review current data regarding ferumoxytol-enhanced MRI and discuss its current/potential applications and future perspectives. ..
  27. doi request reprint Endovascular management of cerebral vasospasm following aneurysm rupture: outcomes and predictors in 116 patients
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, USA
    Clin Neurol Neurosurg 118:26-31. 2014
    ..To retrospectively assess the safety and efficacy of endovascular treatment of cerebral vasospasm with different modalities and assess predictors of outcome...
  28. pmc Localized increase of chemokines in the lumen of human cerebral aneurysms
    Nohra Chalouhi
    Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Stroke 44:2594-7. 2013
    ..The purpose of this study was to determine whether chemokines and chemoattractant cytokines were increased in the lumen of human cerebral aneurysms...
  29. doi request reprint Endovascular treatment of carotid-cavernous fistulas
    Mario Zanaty
    Department of Neurosurgery, Jefferson Hospital for Neuroscience, Thomas Jefferson University, 909 Walnut Street, Philadelphia, PA 19107, USA
    Neurosurg Clin N Am 25:551-63. 2014
    ..This advantage along with the advancement in the field has led to fewer complications with higher success rate. ..
  30. doi request reprint Flow diversion versus conventional treatment for carotid cavernous aneurysms
    Mario Zanaty
    From the Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA M Z, N C, G B, M P S, E W S, N A, S I T, R H R, P J Department of Neurosurgery, University of Virginia, Charlottesville R M S and Department of Neurosurgery, Carver College of Medicine, University of Iowa, Iowa City D H
    Stroke 45:2656-61. 2014
    ..We compared pipeline embolization device (PED) versus conventional endovascular treatment in terms of evolution of mass effect, complications, recurrence, and retreatment rate...
  31. doi request reprint Endovascular management of carotid blowout
    Benjamin Zussman
    Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    World Neurosurg 78:109-14. 2012
    ..To highlight pertinent aspects of emergent endovascular management of carotid rupture, or carotid blowout syndrome (CBS), an emergent, life-threatening complication of head and neck cancer and its treatments...
  32. pmc Novel role for endogenous hepatocyte growth factor in the pathogenesis of intracranial aneurysms
    Ricardo A Peña-Silva
    From the Departments of Pharmacology and Neurosurgery, Medical School, Universidad de Los Andes, Bogota, Colombia R A P S Department of Neurosurgery, Thomas Jefferson University School of Medicine, Philadelphia, PA N C Department of Health and Human Physiology, University of Iowa, Iowa City L W P, G L P Departments of Neurosurgery M A, I M, Y C, D Hasan and Medicine Y C, Z K B, D Heistad, University of Iowa Carver College of Medicine, Iowa City and Department of Medicine, VA Medical Center, Iowa City, IA Z K B
    Hypertension 65:587-93. 2015
    ..HGF and c-Met are expressed in superficial temporal arteries and in intracranial aneurysms. HGF signaling through c-Met may decrease inflammation in endothelial cells and protect against intracranial aneurysm rupture. ..
  33. doi request reprint Stenting as monotherapy for uncoilable intracranial aneurysms
    Ketan R Bulsara
    Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA
    Neurosurgery 73:ons80-5; discussion ons85. 2013
    ..The use of oversized self-expanding stents as monotherapy for BLAs is a relatively new and promising concept that warrants further investigation...
  34. doi request reprint Molecular imaging of cerebrovascular lesions
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, USA
    Transl Stroke Res 5:260-8. 2014
    ..However, studies in human subjects have yet to be performed. In this paper, we review current data regarding ferumoxytol-enhanced MRI and MPO-specific paramagnetic MR contrast agent and discuss current and future applications. ..
  35. doi request reprint The superior ophthalmic vein approach for the treatment of carotid-cavernous fistulas: a novel technique using Onyx
    Nohra Chalouhi
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania 19107, USA
    Neurosurg Focus 32:E13. 2012
    ..The purpose of this study is to assess the safety and efficacy of Onyx embolization of CCFs through a surgical cannulation of the SOV...
  36. doi request reprint Computed tomography perfusion-based selection of patients for endovascular recanalization
    Peter S Amenta
    Thomas Jefferson University Hospital, Hospital for Neurosciences, Philadelphia, Pennsylvania, USA
    Neurosurg Focus 30:E6. 2011
    ..Future endeavors must prospectively evaluate the utility and safety of CT perfusion-based selection of candidates for endovascular intervention...
  37. doi request reprint Stress cardiomyopathy with an "inverse" takotsubo pattern in a patient with acute aneurysmal subarachnoid hemorrhage
    Christine J Waller
    University of Iowa, Iowa City, IA
    Echocardiography 30:E224-6. 2013
    ..Subarachnoid hemorrhage (SAH) induced myocardial dysfunction (often labeled neurogenic stunned myocardium) encompasses a spectrum of clinical presentations ranging from an isolated elevation of cardiac enzymes to cardiogenic shock...
  38. doi request reprint Risk of ventriculostomy-related hemorrhage in patients with acutely ruptured aneurysms treated using stent-assisted coiling
    David K Kung
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    J Neurosurg 114:1021-7. 2011
    ..The aim of this study was to directly quantify the risk of ventriculostomy-related hemorrhage in patients with acute aneurysmal subarachnoid hemorrhage treated with stent-assisted coiling...