Grant A Hartzog

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast
    Marta Radman-Livaja
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
    PLoS Genet 8:e1002811. 2012
  2. pmc The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, CA 95064, USA
    Biochim Biophys Acta 1829:105-15. 2013
  3. pmc Analysis of a splice array experiment elucidates roles of chromatin elongation factor Spt4-5 in splicing
    Yuanyuan Xiao
    Department of Epidemiology and Biostatistics, Center for Bioinformatics and Molecular Biostatistics, University of California, San Francisco, California, United States of America
    PLoS Comput Biol 1:e39. 2005
  4. ncbi request reprint Transcript elongation on a nucleoprotein template
    Grant A Hartzog
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    Biochim Biophys Acta 1577:276-86. 2002
  5. doi request reprint Just the FACTs: histone H2B ubiquitylation and nucleosome dynamics
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Mol Cell 31:2-4. 2008
  6. pmc The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
    Sharon L Squazzo
    Department of MCD Biology, University of California, Santa Cruz, CA 95064, USA
    EMBO J 21:1764-74. 2002
  7. ncbi request reprint A new role for histone tail modifications in transcription elongation
    Grant A Hartzog
    Department of Molecular, Cell, and Developmental Biology, University of California at Santa Cruz, Santa Cruz, California 95064, USA
    Genes Dev 21:3209-13. 2007
  8. ncbi request reprint Transcription elongation by RNA polymerase II
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, California 95064, USA
    Curr Opin Genet Dev 13:119-26. 2003
  9. pmc Structural determination of NSC 670224, synthesis of analogues and biological evaluation
    Nathaniel B Zuckerman
    Department of Chemistry and Biochemistry, University of California, Santa Cruz UCSC, Santa Cruz, CA 95064, USA
    ChemMedChem 7:761-5. 2012

Collaborators

  • Yuanyuan Xiao
  • Jennifer A Armstrong
  • Fred van Leeuwen
  • Karen M Arndt
  • Mark R Segal
  • Nathaniel B Zuckerman
  • Tiffani K Quan
  • Marta Radman-Livaja
  • Sharon L Squazzo
  • Laura J Lee
  • Andrew S Myers
  • Tibor van Welsem
  • Taesoo Kim
  • Oliver J Rando
  • Joseph P Konopelski
  • Stephen Buratowski
  • Walter M Bray
  • Lourdes Valenzuela
  • R Scott Lokey
  • Derek L Lindstrom
  • Andrew J Link
  • Patrick J Costa
  • Rajna Simic
  • Jennifer L Jennings
  • Kathryn E Kumer

Detail Information

Publications9

  1. pmc A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast
    Marta Radman-Livaja
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
    PLoS Genet 8:e1002811. 2012
    ..Taken together, our results emphasize a role for Chd1 in histone replacement in both budding yeast and Drosophila melanogaster, and surprisingly they show that the major effects of Chd1 on turnover occur at the 3' ends of genes...
  2. pmc The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, CA 95064, USA
    Biochim Biophys Acta 1829:105-15. 2013
    ..This article is part of a Special Issue entitled: RNA polymerase II Transcript Elongation...
  3. pmc Analysis of a splice array experiment elucidates roles of chromatin elongation factor Spt4-5 in splicing
    Yuanyuan Xiao
    Department of Epidemiology and Biostatistics, Center for Bioinformatics and Molecular Biostatistics, University of California, San Francisco, California, United States of America
    PLoS Comput Biol 1:e39. 2005
    ..Our results suggest that the Spt4-Spt5 complex may help coordinate splicing with transcription under conditions that present kinetic challenges to spliceosome assembly or function...
  4. ncbi request reprint Transcript elongation on a nucleoprotein template
    Grant A Hartzog
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    Biochim Biophys Acta 1577:276-86. 2002
    ..The C-terminal repeated domain (CTD) of Pol II may also play a role in regulating elongation through chromatin...
  5. doi request reprint Just the FACTs: histone H2B ubiquitylation and nucleosome dynamics
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Mol Cell 31:2-4. 2008
    ....
  6. pmc The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
    Sharon L Squazzo
    Department of MCD Biology, University of California, Santa Cruz, CA 95064, USA
    EMBO J 21:1764-74. 2002
    ..Taken together, these data suggest that the Paf1 complex functions during the elongation phase of transcription in conjunction with Spt4-Spt5 and Spt16-Pob3...
  7. ncbi request reprint A new role for histone tail modifications in transcription elongation
    Grant A Hartzog
    Department of Molecular, Cell, and Developmental Biology, University of California at Santa Cruz, Santa Cruz, California 95064, USA
    Genes Dev 21:3209-13. 2007
  8. ncbi request reprint Transcription elongation by RNA polymerase II
    Grant A Hartzog
    Department of MCD Biology, University of California, Santa Cruz, California 95064, USA
    Curr Opin Genet Dev 13:119-26. 2003
    ..Finally, a combination of genetic analysis and the localization of factors on transcribed chromatin is being used to confirm a role for factors in elongation...
  9. pmc Structural determination of NSC 670224, synthesis of analogues and biological evaluation
    Nathaniel B Zuckerman
    Department of Chemistry and Biochemistry, University of California, Santa Cruz UCSC, Santa Cruz, CA 95064, USA
    ChemMedChem 7:761-5. 2012
    ..The structure of NSC 670224, previously thought to be a 2,4-dichloro arene, was established as the 3,4-dichloro arene, and a focused library of analogues were synthesized and biologically evaluated...