Richard E Harris

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Characterization and consequences of pain variability in individuals with fibromyalgia
    Richard E Harris
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3670-4. 2005
  2. pmc Acupressure for persistent cancer-related fatigue in breast cancer survivors (AcuCrft): a study protocol for a randomized controlled trial
    Suzanna Maria Zick
    Department Family Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA
    BMC Complement Altern Med 12:132. 2012
  3. doi request reprint Imaging central neurochemical alterations in chronic pain with proton magnetic resonance spectroscopy
    Richard E Harris
    University of Michigan, Department of Anesthesiology, 24 Frank Lloyd Wright Drive, P O Box 385, Lobby M, Ann Arbor, MI 48106, United States
    Neurosci Lett 520:192-6. 2012
  4. ncbi request reprint Decreased central mu-opioid receptor availability in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 27:10000-6. 2007
  5. ncbi request reprint Comparison of clinical and evoked pain measures in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 7:521-7. 2006
  6. doi request reprint Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia
    Richard E Harris
    University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
    Arthritis Rheum 58:903-7. 2008
  7. ncbi request reprint Using acupressure to modify alertness in the classroom: a single-blinded, randomized, cross-over trial
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:673-9. 2005
  8. ncbi request reprint Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:663-71. 2005
  9. pmc Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs)
    Richard E Harris
    Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:1077-85. 2009
  10. pmc Elevated insular glutamate in fibromyalgia is associated with experimental pain
    Richard E Harris
    University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
    Arthritis Rheum 60:3146-52. 2009

Research Grants

  1. Mechanisms of Acupuncture Analgesia
    Richard Harris; Fiscal Year: 2006

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Characterization and consequences of pain variability in individuals with fibromyalgia
    Richard E Harris
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3670-4. 2005
    ..We used electronic assessment data derived from a study of patients with fibromyalgia (FM) to examine variability of pain over time and to investigate the implications of pain fluctuation in the context of a clinical trial...
  2. pmc Acupressure for persistent cancer-related fatigue in breast cancer survivors (AcuCrft): a study protocol for a randomized controlled trial
    Suzanna Maria Zick
    Department Family Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA
    BMC Complement Altern Med 12:132. 2012
    ....
  3. doi request reprint Imaging central neurochemical alterations in chronic pain with proton magnetic resonance spectroscopy
    Richard E Harris
    University of Michigan, Department of Anesthesiology, 24 Frank Lloyd Wright Drive, P O Box 385, Lobby M, Ann Arbor, MI 48106, United States
    Neurosci Lett 520:192-6. 2012
    ..As such (1)H-MRS may be useful in discovery of novel compounds for chronic pain. Research in these areas may lead to improved diagnosis and treatment of these complex patients...
  4. ncbi request reprint Decreased central mu-opioid receptor availability in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 27:10000-6. 2007
    ..These findings indicate altered endogenous opioid analgesic activity in FM and suggest a possible reason for why exogenous opiates appear to have reduced efficacy in this population...
  5. ncbi request reprint Comparison of clinical and evoked pain measures in fibromyalgia
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 7:521-7. 2006
    ..05). Pain sensitivity as assessed by random paradigms was associated with improvements in clinical FM pain. Sophisticated pain testing paradigms might be responsive to change in clinical trials...
  6. doi request reprint Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia
    Richard E Harris
    University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
    Arthritis Rheum 58:903-7. 2008
    ..This study was carried out to investigate the relationship between changing levels of Glu within the insula and changes in multiple pain domains in patients with FM...
  7. ncbi request reprint Using acupressure to modify alertness in the classroom: a single-blinded, randomized, cross-over trial
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:673-9. 2005
    ..Previous reports have suggested that acupressure is effective in reducing pain and improving sleep quality; however, its effects on alertness have not been characterized...
  8. ncbi request reprint Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency
    Richard E Harris
    Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
    J Altern Complement Med 11:663-71. 2005
    ..DESIGN/SETTINGS/SUBJECTS: A single-site, single-blind, randomized trial of 114 participants diagnosed with fibromyalgia for at least 1 year was performed...
  9. pmc Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs)
    Richard E Harris
    Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:1077-85. 2009
    ..These findings suggest that divergent MOR processes may mediate clinically relevant analgesic effects for acupuncture and sham acupuncture...
  10. pmc Elevated insular glutamate in fibromyalgia is associated with experimental pain
    Richard E Harris
    University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
    Arthritis Rheum 60:3146-52. 2009
    ....
  11. ncbi request reprint Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia
    Samuel A McLean
    Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Neuropsychopharmacology 31:2776-82. 2006
    ..Further studies are needed to better understand the nature of the association between CSF CRF and pain symptoms in FM...
  12. doi request reprint Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients
    Richard E Harris
    Assistant Professor, Research Specialist, Professor, Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan Assistant Professor, Research Fellow, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts Senior Director, Director, Pfizer Incorporated, Groton, Connecticut Professor, Department of Radiology, Division of Neuroradiology, University of Michigan, and Department of Diagnostic Radiology, Clinical Sciences Lund, Lund University, Lund, Sweden Assistant Professor, Department of Radiology, Division of Neuroradiology, University of Michigan, and Ann Arbor VA Healthcare System Assistant Professor, Department of Radiology, Division of Neuroradiology, University of Michigan Associate Professor, Department of Neurology, Bergmannsheil, Berufsgenossenschaftliche Universit├Ątsklinik, Ruhr Universitat Bochum, Bochum, Germany
    Anesthesiology 119:1453-64. 2013
    ..However, human brain neuroimaging techniques enable the assessment of functional and neurochemical alterations in patients experiencing chronic pain and how these factors may dynamically change with pharmacologic treatment...
  13. pmc No consistent difference in gray matter volume between individuals with fibromyalgia and age-matched healthy subjects when controlling for affective disorder
    Michael C Hsu
    Department of Physical Medicine and Rehabilitation, University of Michigan Chronic Pain and Fatigue Research Center, 24 Frank Lloyd Wright Drive, Lobby M, PO Box 385, Ann Arbor, MI 48106, USA
    Pain 143:262-7. 2009
    ..470, p<.001). No other significant clusters were found on ROI-based analysis. Our results emphasize the importance of correcting for AD when carrying out VBM studies in chronic pain...
  14. ncbi request reprint Diffusion-weighted and diffusion tensor imaging in fibromyalgia patients: a prospective study of whole brain diffusivity, apparent diffusion coefficient, and fraction anisotropy in different regions of the brain and correlation with symptom severity
    Pia C Sundgren
    Department of Radiology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0030, USA
    Acad Radiol 14:839-46. 2007
  15. ncbi request reprint Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factors
    Thorsten Giesecke
    University of Michigan, Ann Arbor, USA
    Arthritis Rheum 48:2916-22. 2003
    ..In this study, we attempt to identify patient subsets by incorporating these features as well as the degree of hyperalgesia/tenderness, which is a key neurobiologic feature of this illness...
  16. doi request reprint Pain is associated with short leukocyte telomere length in women with fibromyalgia
    Afton L Hassett
    Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 13:959-69. 2012
    ..These preliminary data support a relationship between pain and telomere length...
  17. ncbi request reprint Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia
    Samuel A McLean
    Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Arthritis Rheum 52:3660-9. 2005
    ....
  18. pmc Reduced insular ╬│-aminobutyric acid in fibromyalgia
    Bradley R Foerster
    University of Michigan and Ann Arbor VA Healthcare System, Ann Arbor, Michigan, USA
    Arthritis Rheum 64:579-83. 2012
    ....
  19. pmc Augmented central pain processing in vulvodynia
    Johnson P Hampson
    Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48106, USA
    J Pain 14:579-89. 2013
    ..Moreover, differing central activity between VVD subgroups suggests heterogeneous pathologies within this diagnosis...
  20. pmc Alterations in endogenous opioid functional measures in chronic back pain
    Ilkka K Martikainen
    Molecular and Behavioral Neuroscience Institute, and Departments of Psychiatry, Anesthesiology, Obstetrics and Gynecology, and Radiology, University of Michigan, Ann Arbor, Michigan 48109, Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan 48104, Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, and School of Dentistry, University of Maryland, Baltimore, Maryland 21201
    J Neurosci 33:14729-37. 2013
    ....
  21. pmc Altered excitation-inhibition balance in the brain of patients with diabetic neuropathy
    Myria Petrou
    Department of Radiology, Division of Neuroradiology, University of Michigan, 1500 E Medical Center Drive, SPC 5030, UH B2 A209, Ann Arbor, MI 48109 5030, USA
    Acad Radiol 19:607-12. 2012
    ....
  22. ncbi request reprint Is acupuncture more effective than sham acupuncture in relieving pain in patients with low back pain?
    Daniel J Clauw
    University of Michigan Medical School, Division of Rheumatology, Department of Medicine, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
    Nat Clin Pract Rheumatol 2:362-3. 2006
  23. pmc Disentangling linear and nonlinear brain responses to evoked deep tissue pain
    Marco L Loggia
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Pain 153:2140-51. 2012
    ..Future studies should apply a similar approach using innocuous stimuli of multiple intensities to evaluate whether the response profiles reported here can also be generalized to nonpainful somatosensory processing...
  24. doi request reprint Examination of the association of diet and persistent cancer-related fatigue: a pilot study
    Suzanna M Zick
    Department of Family Medicine, University of Michigan Health System, Ann Arbor, MI, USA
    Oncol Nurs Forum 40:E41-9. 2013
    ..To examine associations between diet and persistent cancer-related fatigue (PCRF) in cancer survivors...
  25. pmc Changes in regional gray matter volume in women with chronic pelvic pain: a voxel-based morphometry study
    Sawsan As-Sanie
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109, USA
    Pain 153:1006-14. 2012
    ....
  26. ncbi request reprint How do we know that the pain in fibromyalgia is "real"?
    Richard E Harris
    Department of Medicine, Division of Rheumatology, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 18106, USA
    Curr Pain Headache Rep 10:403-7. 2006
    ..Future studies that focus on central neurobiological and/or genetic influences in fibromyalgia may bring insight into mechanisms of this problematic disease and ultimately result in improved treatments...
  27. pmc Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision
    Samuel A McLean
    Department of Anesthesiology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC 27599, USA
    J Pain 12:101-7. 2011
    ..038). These findings suggest that genetic variations affecting stress response system function influence the somatic and psychological response to MVC, and provide the first evidence of genetic risk for clinical symptoms after MVC...
  28. doi request reprint Reduced Insular Glutamine and N-acetylaspartate in systemic lupus erythematosus: a single-voxel (1)H-MR spectroscopy study
    Patricia Cagnoli
    Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor, MI
    Acad Radiol 20:1286-96. 2013
    ....
  29. pmc Newer treatments for fibromyalgia syndrome
    Richard E Harris
    Department of Anesthesiology, The University of Michigan, Ann, Arbor, MI, USA
    Ther Clin Risk Manag 4:1331-42. 2008
    ..Future studies are needed to validate the efficacy of milnacipran in fibromyalgia...
  30. ncbi request reprint Policy for therapeutic acupuncture in an academic health center: a model for standard policy development
    Monica Myklebust
    University of Michigan Integrative Medicine Clinical Services, Department of Family Medicine, University of Michigan, Ann Arbor, MI 40106, USA
    J Altern Complement Med 12:1035-9. 2006
    ..It may function as a generalizable template for standard policy development by institutions incorporating acupuncture...
  31. ncbi request reprint A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma
    John E Levine
    University of Michigan Medical Center, Ann Arbor, USA
    Blood 101:2476-82. 2003
    ..In summary, alloSC transplantation for LBL is associated with fewer relapses than with autoSC transplantation, but higher TRM offsets any potential survival benefit...
  32. ncbi request reprint Differences in unpleasantness induced by experimental pressure pain between patients with fibromyalgia and healthy controls
    Frank Petzke
    Department of Anesthesiology of the University of Cologne, Germany
    Eur J Pain 9:325-35. 2005
    ..Clinical pain in patients with FM was perceived to be more unpleasant than the evoked pain stimuli. These results are consistent with the concept that chronic pain may reduce the relative unpleasantness of evoked pain sensations...
  33. pmc Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia
    John E Wagner
    Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Blood and Marrow Transplant Program, Minneapolis, MN 55455, USA
    Blood 109:2256-62. 2007
    ....
  34. ncbi request reprint Matched sibling donor haematopoietic stem cell transplantation in Fanconi anaemia: an update of the Cincinnati Children's experience
    Azadeh Farzin
    Divisions of Hematology Oncology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
    Br J Haematol 136:633-40. 2007
    ..These data indicate excellent long-term outcomes and serve as a reference for newer radiation-free preparative regimes that may reduce the risk of late secondary malignancy...
  35. ncbi request reprint Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941)
    Mohammad Jarrar
    Department of Pediatrics, Division of Hematology Oncology, USC Keck School of Medicine, Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 47:141-6. 2006
    ....
  36. ncbi request reprint Comparison of graft-versus-host-disease and survival after HLA-identical sibling bone marrow transplantation in ethnic populations
    Hakumei Oh
    GVHD Immune Reconstitution Wroking Committee of the International Bone Marrow Transplant Registry, Health Policy Institute, Medical College of Wisconsin, Milaukee, WI, USA
    Blood 105:1408-16. 2005
    ..04) and chronic (RR = 3.16; P = .002) GVHD. No differences in other clinical outcomes were noted. Our findings suggest that ethnicity may influence the risk for GVHD, though overall survival rates after transplantation remain similar...
  37. ncbi request reprint Dissociated retinal neurons form periodically active synaptic circuits
    Richard E Harris
    Synapse Formation and Function Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurophysiol 88:188-95. 2002
    ..These results suggest that synaptic depression may regulate the frequency of network activity. Together, these findings provide insight into how networks containing primarily excitatory connections generate highly correlated activity...

Research Grants2

  1. Mechanisms of Acupuncture Analgesia
    Richard Harris; Fiscal Year: 2006
    ..There is a strong institutional commitment to see the applicant succeed in this task due to a tremendous need for well-trained clinical investigators in alternative and complementary medicine. ..