Andrew C Harris

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 171:140-7. 2004
  2. ncbi request reprint Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 196:649-60. 2008
  3. doi request reprint Mecamylamine elicits withdrawal-like signs in rats following a single dose of nicotine
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 225:291-302. 2013
  4. pmc Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St, S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 220:565-76. 2012
  5. pmc Correlates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit dose
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 205:599-611. 2009
  6. pmc A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th Street, S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 217:153-66. 2011
  7. doi request reprint Compensatory nicotine self-administration in rats during reduced access to nicotine: an animal model of smoking reduction
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Exp Clin Psychopharmacol 16:86-97. 2008
  8. pmc Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, United States
    Pharmacol Biochem Behav 96:217-27. 2010
  9. pmc Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats
    SAMUEL A ROIKO
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Pharmacol Biochem Behav 93:105-11. 2009
  10. ncbi request reprint Prevalence, magnitude, and correlates of an extinction burst in drug-seeking behavior in rats trained to self-administer nicotine during unlimited access (23 h/day) sessions
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 194:395-402. 2007

Research Grants

  1. Compensation of Nicotine Self-Administration
    Andrew Harris; Fiscal Year: 2007

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 171:140-7. 2004
    ..Although anxiety is a common symptom of opiate withdrawal, few studies have examined the effects of morphine withdrawal on acoustic startle...
  2. ncbi request reprint Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 196:649-60. 2008
    ..While the N-methyl-D: -aspartate (NMDA) glutamate receptor has been strongly implicated in chronic opiate dependence, relatively few studies have examined the effects of NMDA receptor antagonists on withdrawal from acute opiate exposure...
  3. doi request reprint Mecamylamine elicits withdrawal-like signs in rats following a single dose of nicotine
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 225:291-302. 2013
    ..Emerging evidence suggests that symptoms of nicotine withdrawal may occur following only a few cigarettes. Whether acute exposure to nicotine can induce dependence in animals has not been well established...
  4. pmc Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St, S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 220:565-76. 2012
    ..Models using tobacco extracts derived from tobacco products and containing a range of tobacco constituents might more accurately simulate tobacco exposure in humans...
  5. pmc Correlates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit dose
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 205:599-611. 2009
    ..Characterizing factors contributing to the marked individual variability in compensation may be useful for understanding this phenomenon and assessing the feasibility of harm reduction interventions...
  6. pmc A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th Street, S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 217:153-66. 2011
    ..Compensatory smoking may represent an adverse consequence of smoking reduction or the use of reduced-nicotine tobacco products. Factors contributing to individual variability in compensation are poorly understood...
  7. doi request reprint Compensatory nicotine self-administration in rats during reduced access to nicotine: an animal model of smoking reduction
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Exp Clin Psychopharmacol 16:86-97. 2008
    ..This model may be useful for characterizing underlying factors and potential consequences of compensatory smoking...
  8. pmc Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats
    Andrew C Harris
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, United States
    Pharmacol Biochem Behav 96:217-27. 2010
    ....
  9. pmc Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats
    SAMUEL A ROIKO
    Minneapolis Medical Research Foundation, Minneapolis, MN 55404, USA
    Pharmacol Biochem Behav 93:105-11. 2009
    ..The Nic311 doses used have been shown to attenuate the behavioral effects of nicotine, suggesting that the use of passive immunization to treat nicotine addiction is not likely to precipitate withdrawal...
  10. ncbi request reprint Prevalence, magnitude, and correlates of an extinction burst in drug-seeking behavior in rats trained to self-administer nicotine during unlimited access (23 h/day) sessions
    Andrew C Harris
    Minneapolis Medical Research Foundation, 914 South 8th St S 3 Labs, 860, Minneapolis, MN 55404, USA
    Psychopharmacology (Berl) 194:395-402. 2007
    ..e., an "extinction burst"). However, the presence of an extinction burst in animal models of nicotine self-administration (NSA) has not been studied extensively...
  11. ncbi request reprint Potentiated startle and hyperalgesia during withdrawal from acute morphine: effects of multiple opiate exposures
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 176:266-73. 2004
    ..Previous acute dependence studies have demonstrated escalated withdrawal severity following multiple withdrawal episodes...
  12. pmc Combined active and passive immunization against nicotine: minimizing monoclonal antibody requirements using a target antibody concentration strategy
    Katherine E Cornish
    Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA
    Int Immunopharmacol 11:1809-15. 2011
    ..However, variability in serum NicAb levels with combination immunotherapy may make translation of this approach challenging...
  13. doi request reprint Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats
    SAMUEL A ROIKO
    Minneapolis Medical Research Foundation, Minneapolis, Minnesota, USA
    J Pharmacol Exp Ther 325:985-93. 2008
    ..These data indicate that providing higher serum NicAb concentrations improves the efficacy of immunotherapy against nicotine and that supplementing vaccination with passive immunization is a potential strategy to accomplish this...
  14. ncbi request reprint HPA axis dysregulation following prenatal opiate exposure and postnatal withdrawal
    Kathryn L Hamilton
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, United States
    Neurotoxicol Teratol 27:95-103. 2005
    ..These results suggest that prenatal opiate exposure followed by postnatal withdrawal dysregulated the HPA axis response to stressors in the neonate and adult and differentially affected adult anxiety-like behavior in males and females...
  15. ncbi request reprint Acute opioid dependence: characterizing the early adaptations underlying drug withdrawal
    Andrew C Harris
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
    Psychopharmacology (Berl) 178:353-66. 2005
    ..This phenomenon, termed acute dependence, may be useful in understanding the early stages of opioid dependence and addiction...

Research Grants1

  1. Compensation of Nicotine Self-Administration
    Andrew Harris; Fiscal Year: 2007
    ....