Denham Harman

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. ncbi request reprint Free radical theory of aging: an update: increasing the functional life span
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, Nebraska Medical Center, Omaha, 68198 4635, USA
    Ann N Y Acad Sci 1067:10-21. 2006
  2. ncbi request reprint Alzheimer's disease pathogenesis: role of aging
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, 984635 Nebraska Medical Center, Omaha, 68198 4635, USA
    Ann N Y Acad Sci 1067:454-60. 2006
  3. doi request reprint Origin and evolution of the free radical theory of aging: a brief personal history, 1954–2009
    Denham Harman
    University of Nebraska Medical Center College of Medicine, Omaha, NE 68198 4635, USA
    Biogerontology 10:773-81. 2009
  4. ncbi request reprint The free radical theory of aging
    Denham Harman
    University of Nebraska College of Medicine, Department of Medicine, Omaha, NE 68198 4635, USA
    Antioxid Redox Signal 5:557-61. 2003
  5. ncbi request reprint Alzheimer's disease: role of aging in pathogenesis
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, Omaha, Nebraska 68198 4635, USA
    Ann N Y Acad Sci 959:384-95; discussion 463-5. 2002
  6. ncbi request reprint "I thought, thought, thought for four months in vain and suddenly the idea came"--an interview with Denham and Helen Harman. Interview by K. Kitani and G.O. Ivy
    Denham Harman
    Biogerontology 4:401-12. 2003

Detail Information

Publications6

  1. ncbi request reprint Free radical theory of aging: an update: increasing the functional life span
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, Nebraska Medical Center, Omaha, 68198 4635, USA
    Ann N Y Acad Sci 1067:10-21. 2006
    ..The extensive studies based on the FRTA hold promise that ALE-B and the MLS can be extended, the ALE-B possibly by a few years, and the MLS somewhat less...
  2. ncbi request reprint Alzheimer's disease pathogenesis: role of aging
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, 984635 Nebraska Medical Center, Omaha, 68198 4635, USA
    Ann N Y Acad Sci 1067:454-60. 2006
    ..The hypothesis suggests convenient, effective measures to prevent and treat, for example, by decreasing brain OxS levels with oral antioxidants such as lipoic or dehydroascorbic acids that are capable of passing the blood-brain barrier...
  3. doi request reprint Origin and evolution of the free radical theory of aging: a brief personal history, 1954–2009
    Denham Harman
    University of Nebraska Medical Center College of Medicine, Omaha, NE 68198 4635, USA
    Biogerontology 10:773-81. 2009
    ....
  4. ncbi request reprint The free radical theory of aging
    Denham Harman
    University of Nebraska College of Medicine, Department of Medicine, Omaha, NE 68198 4635, USA
    Antioxid Redox Signal 5:557-61. 2003
    ..Aging changes may be caused by free radical reactions. The extensive studies based on this possibility hold promise that the ALE-B can be extended to >85 years and the maximum life span increased...
  5. ncbi request reprint Alzheimer's disease: role of aging in pathogenesis
    Denham Harman
    Department of Medicine, University of Nebraska College of Medicine, Omaha, Nebraska 68198 4635, USA
    Ann N Y Acad Sci 959:384-95; discussion 463-5. 2002
    ..SAD may be due to increased SO formation caused by mutations in the approximately 1000 genes involved in mitochondrial biogenesis and function. The hypothesis suggests measures to prevent and treat...
  6. ncbi request reprint "I thought, thought, thought for four months in vain and suddenly the idea came"--an interview with Denham and Helen Harman. Interview by K. Kitani and G.O. Ivy
    Denham Harman
    Biogerontology 4:401-12. 2003