Andrew D Hanson

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. pmc Metabolism of the folate precursor p-aminobenzoate in plants: glucose ester formation and vacuolar storage
    Aymerick Eudes
    Departments of Horticultural Sciences and Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    J Biol Chem 283:15451-9. 2008
  2. pmc Synergistic use of plant-prokaryote comparative genomics for functional annotations
    Svetlana Gerdes
    Fellowship for Interpretation of Genomes, Burr Ridge, IL, USA
    BMC Genomics 12:S2. 2011
  3. ncbi request reprint Synthesis and turnover of folates in plants
    Andrew D Hanson
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Curr Opin Plant Biol 5:244-9. 2002
  4. ncbi request reprint Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase
    Gilles J C Basset
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant J 40:453-61. 2004
  5. pmc Identification and characterization of the missing pyrimidine reductase in the plant riboflavin biosynthesis pathway
    Ghulam Hasnain
    Department of Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 161:48-56. 2013
  6. ncbi request reprint Higher plant plastids and cyanobacteria have folate carriers related to those of trypanosomatids
    Sebastian M J Klaus
    Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 280:38457-63. 2005
  7. ncbi request reprint 5-Formyltetrahydrofolate is an inhibitory but well tolerated metabolite in Arabidopsis leaves
    Aymeric Goyer
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 280:26137-42. 2005
  8. pmc Identification of transport-critical residues in a folate transporter from the folate-biopterin transporter (FBT) family
    Aymerick Eudes
    Horticultural Sciences, Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 285:2867-75. 2010
  9. pmc 6-pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria
    Anne Pribat
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Bacteriol 191:4158-65. 2009
  10. doi request reprint A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism
    Anne Pribat
    Horticultural Sciences Department, University of Florida, Gainesville, 32611, USA
    Funct Integr Genomics 11:467-78. 2011

Collaborators

Detail Information

Publications56

  1. pmc Metabolism of the folate precursor p-aminobenzoate in plants: glucose ester formation and vacuolar storage
    Aymerick Eudes
    Departments of Horticultural Sciences and Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    J Biol Chem 283:15451-9. 2008
    ..In total, these data and the fact that isolated mitochondria did not take up [(3)H]pABA-Glc, suggest that the glucose ester represents a storage form of pABA that does not contribute directly to folate synthesis...
  2. pmc Synergistic use of plant-prokaryote comparative genomics for functional annotations
    Svetlana Gerdes
    Fellowship for Interpretation of Genomes, Burr Ridge, IL, USA
    BMC Genomics 12:S2. 2011
    ..This approach bridges the gap between automated homology-based annotations and the classical gene discovery efforts of experimentalists, and is more powerful than purely computational approaches to identifying gene-function associations...
  3. ncbi request reprint Synthesis and turnover of folates in plants
    Andrew D Hanson
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Curr Opin Plant Biol 5:244-9. 2002
    ..Moreover, new analytical advances will help to elucidate plant folate turnover and transport, which are practically unexplored...
  4. ncbi request reprint Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase
    Gilles J C Basset
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant J 40:453-61. 2004
    ..As shown previously for the ADC synthase transcript, the level of ADC lyase mRNA in the pericarp of tomato fruit falls sharply as ripening advances, suggesting that the expression of these two enzymes is coregulated...
  5. pmc Identification and characterization of the missing pyrimidine reductase in the plant riboflavin biosynthesis pathway
    Ghulam Hasnain
    Department of Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 161:48-56. 2013
    ..The role of the COG3236 domain remains mysterious; no evidence was obtained for the possibility that it catalyzes the dephosphorylation that follows pyrimidine reduction...
  6. ncbi request reprint Higher plant plastids and cyanobacteria have folate carriers related to those of trypanosomatids
    Sebastian M J Klaus
    Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 280:38457-63. 2005
    ..These findings establish conservation of function among folate and biopterin transporter family proteins from three kingdoms of life...
  7. ncbi request reprint 5-Formyltetrahydrofolate is an inhibitory but well tolerated metabolite in Arabidopsis leaves
    Aymeric Goyer
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 280:26137-42. 2005
    ..However, the near-normal growth of the mutant shows that even exceptionally high 5-CHO-THF levels do not much affect fluxes through SHMT or any other folate-dependent reaction, i.e. that 5-CHO-THF is well tolerated in plants...
  8. pmc Identification of transport-critical residues in a folate transporter from the folate-biopterin transporter (FBT) family
    Aymerick Eudes
    Horticultural Sciences, Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 285:2867-75. 2010
    ..coli. Such negative data could reflect roles in transport of other substrates. These studies provide the first insights into the native structure and catalytic mechanism of FBT family carriers...
  9. pmc 6-pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria
    Anne Pribat
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Bacteriol 191:4158-65. 2009
    ....
  10. doi request reprint A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism
    Anne Pribat
    Horticultural Sciences Department, University of Florida, Gainesville, 32611, USA
    Funct Integr Genomics 11:467-78. 2011
    ..We therefore propose (a) that COG0212 has an unrecognized yet sometimes crucial role in thiamin metabolism, most probably in salvage or detoxification, and (b) that is not a 5-FCL and should no longer be so annotated...
  11. pmc FolX and FolM are essential for tetrahydromonapterin synthesis in Escherichia coli and Pseudomonas aeruginosa
    Anne Pribat
    University of Florida, Horticultural Sciences Department, Gainesville, FL 32611, USA
    J Bacteriol 192:475-82. 2010
    ....
  12. ncbi request reprint Characterization of the folate salvage enzyme p-aminobenzoylglutamate hydrolase in plants
    Gale G Bozzo
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, United States
    Phytochemistry 69:29-37. 2008
    ..The finding that Arabidopsis has folate-hydrolyzing activity points to an enzymatic component of folate degradation in plants...
  13. pmc A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life
    Jeffrey C Waller
    Horticultural Sciences, Food Science and Human Nutrition, Microbiology and Cell Science Departments, and Department of Biochemistry and Molecular Biology and National High Magnetic Field Laboratory, and McKnight Brain Institute, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 107:10412-7. 2010
    ..Thus COG0354 proteins have an ancient, conserved, folate-dependent function in the activity of certain Fe/S cluster enzymes...
  14. doi request reprint A central role for gamma-glutamyl hydrolases in plant folate homeostasis
    Tariq A Akhtar
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant J 64:256-66. 2010
    ....
  15. pmc Folate biosynthesis in higher plants. cDNA cloning, heterologous expression, and characterization of dihydroneopterin aldolases
    Aymeric Goyer
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 135:103-11. 2004
    ..The substantial divergence of FolB homologs in Arabidopsis and other plants suggests that some of them may act on substrates other than DHN...
  16. pmc Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase
    Linda Jeanguenin
    Department of Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 285:41557-66. 2010
    ..Collectively, these data indicate that FTs functionally replace 5-FCL in certain prokaryotes...
  17. pmc Tomato gamma-glutamylhydrolases: expression, characterization, and evidence for heterodimer formation
    Tariq A Akhtar
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant Physiol 148:775-85. 2008
    ..Plant GGH heterodimers thus appear to form wherever different GGH genes are expressed simultaneously and to have catalytic characteristics midway between those of the corresponding homodimers...
  18. doi request reprint Mutational analysis of YgfZ, a folate-dependent protein implicated in iron/sulphur cluster metabolism
    Ghulam Hasnain
    Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, USA
    FEMS Microbiol Lett 326:168-72. 2012
    ..Collectively, these data demonstrate a pivotal role for the Ygf Z motif's cysteine residue and a subsidiary one for the adjacent tyrosine, and help formulate a hypothesis about the folate requirement of Ygf Z proteins...
  19. ncbi request reprint Plant gamma-glutamyl hydrolases and folate polyglutamates: characterization, compartmentation, and co-occurrence in vacuoles
    Giuseppe Orsomando
    Horticultural Sciences and Food Science Department, University of Florida, Gainesville, FL 32611, USA
    J Biol Chem 280:28877-84. 2005
    ..These data point to a hitherto unsuspected role for vacuoles in folate storage. Furthermore, the paradoxical co-occurrence of GGH and folylpolyglutamates in vacuoles implies that the polyglutamates are somehow protected from GGH attack...
  20. pmc Pterin and folate salvage. Plants and Escherichia coli lack capacity to reduce oxidized pterins
    Alexandre Noiriel
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 143:1101-9. 2007
    ..If it is lacking, folate precursors or breakdown products that become oxidized will permanently exit the metabolically active pterin pool...
  21. ncbi request reprint Evidence for folate-salvage reactions in plants
    Giuseppe Orsomando
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant J 46:426-35. 2006
    ..We conclude that plants are excellent organisms in which to explore the biochemistry of folate salvage...
  22. doi request reprint Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals
    Linda Jeanguenin
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Funct Integr Genomics 12:25-34. 2012
    ..More generally, these results indicate that specificity for nicotinate is conserved widely, but not absolutely, among pro- and eukaryotic NiaP family proteins...
  23. pmc Mitochondrial and plastidial COG0354 proteins have folate-dependent functions in iron-sulphur cluster metabolism
    Jeffrey C Waller
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    J Exp Bot 63:403-11. 2012
    ..That plants retain mitochondrial and plastidial COG0354 proteins with distinct phylogenetic origins emphasizes how deeply the extant Fe/S cluster assembly machinery still reflects the ancient endosymbioses that gave rise to plants...
  24. ncbi request reprint Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway
    Aymeric Goyer
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant Cell Physiol 48:232-42. 2007
    ..These data indicate that plants possess an alternative to the reverse trans-sulfuration pathway (methionine-->homocysteine-->cystathionine-->cysteine) in which methanethiol is an intermediate...
  25. pmc Folate synthesis in plants: the first step of the pterin branch is mediated by a unique bimodular GTP cyclohydrolase I
    Gilles Basset
    Horticultural Sciences Department and Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 99:12489-94. 2002
    ..As ripening advances, GCHI expression declines sharply, and folate content drops, suggesting that folate synthesis fails to keep pace with turnover...
  26. doi request reprint Developmental and feedforward control of the expression of folate biosynthesis genes in tomato fruit
    Jeffrey C Waller
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Mol Plant 3:66-77. 2010
    ..Microarray analysis showed that only 14 other transcripts (of 11 000 surveyed) increased in abundance by two-fold or more in high-folate fruit, demonstrating that the induction of folate pathway genes is relatively specific...
  27. ncbi request reprint Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis
    Aymeric Goyer
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 279:16947-53. 2004
    ..These data indicate that pipecolate is the endogenous substrate for SOX in plants and that plants can utilize exogenous sarcosine opportunistically, sarcosine being a common soil metabolite...
  28. pmc Nonflowering plants possess a unique folate-dependent phenylalanine hydroxylase that is localized in chloroplasts
    Anne Pribat
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Plant Cell 22:3410-22. 2010
    ..These data show that nonflowering plants have functional plastidial AAHs, establish an unprecedented electron donor role for a folate, and uncover a novel link between folate and aromatic metabolism...
  29. ncbi request reprint A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants
    Sebastian M J Klaus
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    J Biol Chem 280:5274-80. 2005
    ..and Kraszewska, E. (2002) J. Biol. Chem. 277, 50482-50486). However, we found that this activity is negligible at physiological levels of Mn(2+) and that, with 1 mM Mg(2+), AtNUDT1 prefers DHNTP and (deoxy) nucleoside triphosphates...
  30. doi request reprint Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize
    Océane Frelin
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Funct Integr Genomics 12:317-26. 2012
    ..Our data provide a firm basis to propagate the functional annotation of mitochondrial ThDP carriers to other angiosperm genomes...
  31. ncbi request reprint The folate precursor p-aminobenzoate is reversibly converted to its glucose ester in the plant cytosol
    Eoin P Quinlivan
    Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 278:20731-7. 2003
    ..Esterification of pABA may eliminate such errant behavior and provide a readily reclaimable storage form of pABA as well as a substrate for membrane transporters...
  32. pmc Folate biofortification of tomato fruit
    Rocio I Díaz De La Garza
    Department of Horticultural Sciences, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 104:4218-22. 2007
    ..The folate levels we achieved provide the complete adult daily requirement in less than one standard serving...
  33. ncbi request reprint Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases
    Alexandre Noiriel
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Plant J 51:378-89. 2007
    ..We conclude that pterin aldehyde salvage in plants involves multiple, generalist NADPH-linked reductases, and that the At1g10310 enzyme is typical of these and hence suitable for use in engineering studies of folate turnover...
  34. pmc Mitochondrial phosphatidylserine decarboxylase from higher plants. Functional complementation in yeast, localization in plants, and overexpression in Arabidopsis
    Denis Rontein
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 132:1678-87. 2003
    ..They also indicate that mitochondrial PSD is an important housekeeping enzyme whose expression is strongly regulated at the transcriptional level...
  35. pmc Folate biofortification in tomatoes by engineering the pteridine branch of folate synthesis
    Rocio Diaz De La Garza
    Department of Horticultural Sciences, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 101:13720-5. 2004
    ..These results demonstrate that engineering a moderate increase in pteridine production can significantly enhance the folate content in food plants and that boosting the PABA supply can produce further gains...
  36. pmc Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations
    VALERIE DE CRECY-LAGARD
    Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA
    BMC Genomics 8:245. 2007
    ..This study reports the results of the analysis and integrates them with new and existing experimental data...
  37. pmc Phylogenomic and functional analysis of pterin-4a-carbinolamine dehydratase family (COG2154) proteins in plants and microorganisms
    Valeria Naponelli
    Department of Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 146:1515-27. 2008
    ..Besides this role, we propose that partnerless PCDs support the function of as yet unrecognized pterin-dependent enzymes...
  38. pmc Evidence that the folate-dependent proteins YgfZ and MnmEG have opposing effects on growth and on activity of the iron-sulfur enzyme MiaB
    Jeffrey C Waller
    Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, Florida, USA
    J Bacteriol 194:362-7. 2012
    ..A more plausible explanation is that MnmEG erroneously transfers a folate-bound formaldehyde unit to MiaB and that YgfZ reverses this...
  39. ncbi request reprint Improved methods for the preparation of [3H]folate polyglutamates: biosynthesis with Lactobacillus casei and enzymatic synthesis with Escherichia coli folylpolyglutamate synthetase
    Valeria Naponelli
    Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    Anal Biochem 371:127-34. 2007
    ..This enzymatic synthesis yielded predominantly tri-, tetra-, and pentaglutamyl species for the [(3)H]folate substrate...
  40. pmc 'Unknown' proteins and 'orphan' enzymes: the missing half of the engineering parts list--and how to find it
    Andrew D Hanson
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    Biochem J 425:1-11. 2010
    ..Furthermore, it is cost-efficient and increasingly straightforward to deploy owing to a proliferation of databases and associated tools...
  41. pmc Identification of mitochondrial coenzyme a transporters from maize and Arabidopsis
    Rémi Zallot
    Microbiology and Cell Science Department, University of Florida, Gainesville, Florida 32611, USA
    Plant Physiol 162:581-8. 2013
    ..The highly conserved nature of these carriers makes possible their reliable annotation in other angiosperm genomes...
  42. pmc Folate synthesis in plants: the p-aminobenzoate branch is initiated by a bifunctional PabA-PabB protein that is targeted to plastids
    Gilles J C Basset
    Department of Horticultural Sciences, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 101:1496-501. 2004
    ..In the pericarp of tomato fruit, the PabA-PabB mRNA level fell drastically as ripening advanced, but there was no fall in total PABA content, which stayed between 0.7 and 2.3 nmol.g(-1) fresh weight...
  43. pmc Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes
    Aymerick Eudes
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA
    J Bacteriol 190:7591-4. 2008
    ..Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch...
  44. ncbi request reprint Finding novel metabolic genes through plant-prokaryote phylogenomics
    VALERIE DE CRECY-LAGARD
    Microbiology and Cell Science Department, University of Florida, Gainesville, FL 32611, USA
    Trends Microbiol 15:563-70. 2007
    ..This breaks with the past pattern of gene discovery, in which the information flow was most often unidirectional from prokaryotes to plants...
  45. pmc Tomato aromatic amino acid decarboxylases participate in synthesis of the flavor volatiles 2-phenylethanol and 2-phenylacetaldehyde
    Denise Tieman
    Department of Horticultural Sciences, University of Florida, P O Box 110690, Gainesville, FL 32611 0690, USA
    Proc Natl Acad Sci U S A 103:8287-92. 2006
    ..Besides establishing a biosynthetic route, these results show that it is possible to change phenylalanine-based flavor and aroma volatiles in plants by manipulating expression of a single gene...
  46. doi request reprint Folate biosynthesis, turnover, and transport in plants
    Andrew D Hanson
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Annu Rev Plant Biol 62:105-25. 2011
    ..Understanding these processes, which will require both biochemical and -omics research, should lead to improved biofortification strategies based on transgenic or conventional approaches...
  47. ncbi request reprint Evidence from engineering that decarboxylation of free serine is the major source of ethanolamine moieties in plants
    Denis Rontein
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611 0690, U S A
    Plant Cell Physiol 44:1185-91. 2003
    ..Taken together, these data indicate that serine decarboxylation is the main source of Etn moieties in plants. The ability to enhance serine --> Etn flux should advance engineering of choline and glycine betaine accumulation...
  48. ncbi request reprint Cloning and characterization of mitochondrial 5-formyltetrahydrofolate cycloligase from higher plants
    Sanja Roje
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 277:42748-54. 2002
    ..Consistent with this possibility, 5-FCL activity was far higher in leaf mitochondria than root mitochondria...
  49. doi request reprint Comparative genomics approaches to understanding and manipulating plant metabolism
    Louis M T Bradbury
    Horticultural Sciences Department, University of Florida, Gainesville, FL 32611 0690, USA
    Curr Opin Biotechnol 24:278-84. 2013
    ....
  50. ncbi request reprint The analysis of folate and its metabolic precursors in biological samples
    Eoin P Quinlivan
    Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    Anal Biochem 348:163-84. 2006
  51. pmc Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio
    Michael G Kocsis
    Horticultural Sciences Department, University of Florida, Gainesville 32611, USA
    Plant Physiol 131:1808-15. 2003
    ..These data indicate that the SMM cycle contributes to regulation of Ado-Met levels rather than preventing depletion of free Met...
  52. ncbi request reprint Metabolic engineering of osmoprotectant accumulation in plants
    Denis Rontein
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    Metab Eng 4:49-56. 2002
    ....
  53. ncbi request reprint Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo
    Sanja Roje
    Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 277:4056-61. 2002
    ..Possibly related to this shift in one-carbon fluxes, total folate levels are doubled in yeast cells expressing Chimera-1...
  54. ncbi request reprint Folate biofortification in food plants
    Samir Bekaert
    Department of Molecular Genetics, Ghent University, K L Ledeganckstraat 35, B 9000 Gent, Belgium
    Trends Plant Sci 13:28-35. 2008
    ..Here, we review the current status of investigations in the field of folate enhancement on the eve of a new era in food fortification...
  55. pmc Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase
    Tobias Sahr
    Laboratoire de Physiologie Cellulaire Végétale, UMR5168 CNRS CEA INRA Université Joseph Fourier Grenoble I, Departement Reponse et Dynamique Cellulaires, CEA Grenoble, 17 rue des Martyrs, F 38054 Grenoble Cedex 9, France
    Biochem J 396:157-62. 2006
    ..These findings support the view that the monomeric ADC synthase is a potential target for antifolate drugs...
  56. pmc Deficiency in phosphatidylserine decarboxylase activity in the psd1 psd2 psd3 triple mutant of Arabidopsis affects phosphatidylethanolamine accumulation in mitochondria
    Annika Nerlich
    Max Planck Institute of Molecular Plant Physiology, Department of Molecular Physiology, 14476 Potsdam, Germany
    Plant Physiol 144:904-14. 2007
    ..These results imply that, similar to yeast and animal cells, a specific phospholipid transfer from the endoplasmic reticulum to mitochondria exists in plants...