Research Topics
| Richard HansenSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Patterns in nursing home medication errors: disproportionality analysis as a novel method to identify quality improvement opportunitiesRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599 7573, USA
Pharmacoepidemiol Drug Saf 19:1087-94. 2010..This approach can supplement descriptive data and target quality improvement efforts...
Efficacy and tolerability of second-generation antidepressants in social anxiety disorderRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA
Int Clin Psychopharmacol 23:170-9. 2008..Overall, a fair amount of evidence supports the efficacy of escitalopram, fluvoxamine, paroxetine, sertraline, and venlafaxine in social anxiety disorder. The drugs do not differ in efficacy, although their adverse event profiles do...
Medication therapy management services in North Carolina community pharmacies: current practice patterns and projected demandRichard A Hansen
School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, Campus Box 7360, Chapel Hill, NC 27599, USA
J Am Pharm Assoc (2003) 46:700-6. 2006....- Functional outcomes of drug treatment in Alzheimer's disease: A systematic review and meta-analysisRichard A Hansen
School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Drugs Aging 24:155-67. 2007..Patient functioning is an important outcome in Alzheimer's disease, but treatment-related improvements in patient function are difficult to quantify because a number of different scales are used in its measurement... - Serious adverse events with infliximab: analysis of spontaneously reported adverse eventsRichard A Hansen
Center for Pharmaceutical Outcomes and Policy, Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Clin Gastroenterol Hepatol 5:729-35. 2007..The aims of this study were to explore adverse event signals with infliximab by using a long period of post-marketing experience, stratifying by indication... - Geographic Information System mapping as a tool to assess nonresponse bias in survey researchRichard A Hansen
School of Pharmacy, University of North Carolina at Chapel Hill, Campus Box 7360, Chapel Hill, NC 27599, USA
Res Social Adm Pharm 3:249-64. 2007..In a 2005 survey of North Carolina community pharmacy managers using a Web-based data collection instrument, we achieved an overall response rate of 23%... - Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysisRichard A Hansen
School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Clin Interv Aging 3:211-25. 2008..63 and 1.42, respectively). Indirect comparisons also favored donepezil over galantamine with regard to behavior. Across trials, the incidence of adverse events was generally lowest for donepezil and highest for rivastigmine... - Meta-analysis of major depressive disorder relapse and recurrence with second-generation antidepressantsRichard Hansen
Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
Psychiatr Serv 59:1121-30. 2008..This meta-analysis reviewed data on the efficacy and effectiveness of second-generation antidepressants for preventing major depression relapse and recurrence during continuation and maintenance phases of treatment, respectively... - Controlling for drug dose in systematic review and meta-analysis: a case study of the effect of antidepressant doseRichard A Hansen
School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
Med Decis Making 29:91-103. 2009..Second-generation antidepressants are used as an example to illustrate this method and to determine whether dose influences conclusions on comparative effectiveness... - Comparison of methods to assess medication adherence and classify nonadherenceRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Campus Box 7360, 2205 Kerr Hall, Chapel Hill, NC 27599, USA
Ann Pharmacother 43:413-22. 2009..Various measures of medication adherence exist, but there is controversy regarding which measures provide acceptable data and how nonadherence should be defined... - Predialysis chronic kidney disease: evaluation of quality of life in clinic patients receiving comprehensive anemia careRichard A Hansen
University of North Carolina at Chapel Hill, School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, Chapel Hill, NC 27599, USA
Res Social Adm Pharm 5:143-53. 2009..Anemia is common in chronic kidney disease (CKD), and suboptimal management of anemia can lead to serious health complications and poor quality of life (QOL)... - Prescription refill records as a screening tool to identify antidepressant non-adherenceRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Pharmacoepidemiol Drug Saf 19:33-7. 2010..Accordingly, our purpose was to determine the shortest gap in medication supply that is predictive of discontinuation, while minimizing false positive results... - A retrospective cohort study of economic outcomes and adherence to monotherapy with metformin, pioglitazone, or a sulfonylurea among patients with type 2 diabetes mellitus in the United States from 2003 to 2005Richard A Hansen
University of North Carolina, Chapel Hill, 27599, USA
Clin Ther 32:1308-19. 2010.... - Methodological challenges surrounding direct-to-consumer advertising research--the measurement conundrumRichard A Hansen
University of North Carolina at Chapel Hill, Division of Pharmaceutical Policy and Evaluative Sciences, CB 7360 205M Beard Hall, Chapel Hill, NC 27599, USA
Res Social Adm Pharm 1:331-47. 2005.... - Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorderRichard A Hansen
Division of Pharmaceutical Policy and Evaluative Sciences, University of North Carolina, Chapel Hill, North Carolina 27599, USA
Ann Intern Med 143:415-26. 2005.... - The association of consumer cost-sharing and direct-to-consumer advertising with prescription drug useRichard A Hansen
University of North Carolina at Chapel Hill, Division of Pharmaceutical Policy and Evaluative Sciences, CB 7360, Room 205M, Beard Hall, Chapel Hill, NC 27599, USA
Res Social Adm Pharm 1:139-57. 2005..Previous research on the impact of various cost-sharing strategies on prescription drug use has not considered the impact of direct-to-consumer (DTC) advertising... - Factors influencing the shift of patients from one proton pump inhibitor to another: the effect of direct-to-consumer advertisingRichard A Hansen
Division of Pharmaceutical Policy and Evaluative Sciences, University of North Carolina, Chapel Hill, NC 27599, USA
Clin Ther 27:1478-87. 2005..Switching from one proton pump inhibitor (PPI) to another is common, and may be related to factors other than efficacy and tolerability... - Types of medication errors in North Carolina nursing homes: a target for quality improvementRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Am J Geriatr Pharmacother 4:52-61. 2006..Gaining a better understanding of the types of medications commonly involved in medication errors in nursing homes would be an important step toward quality improvement... - Depression affects adherence measurement but not the effectiveness of an adherence intervention in heart failure patientsRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA
J Am Pharm Assoc (2003) 49:760-8. 2009.... - Preventing medication errors in long-term care: results and evaluation of a large scale web-based error reporting systemStephanie Pierson
Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7590, USA
Qual Saf Health Care 16:297-302. 2007..To describe the implementation and evaluation of a web-based medication error reporting system... - Repeat medication errors in nursing homes: Contributing factors and their association with patient harmDaniel J Crespin
Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Am J Geriatr Pharmacother 8:258-70. 2010..Medication errors are highly prevalent in long-term care facilities and are responsible for preventable injury. Repeat medication errors, or identical events occurring multiple times in the same patient, may be particularly preventable... - Second-generation antidepressant discontinuation and depressive relapse in adult patients with bipolar depression: results of a retrospective database analysisAlex Z Fu
Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, Ohio 44195, and Division of Pharmaceutical Outcomes and Policy, University of North Carolina, Chapel Hill, USA
Clin Ther 28:979-89. 2006..To date, few postmarketing studies have addressed whether long-term prophylactic treatment with second-generation antidepressants (ADs) delays depressive episodes in patients with bipolar disorder... - Direct-to-consumer and physician promotion of tegaserod correlated with physician visits, diagnoses, and prescriptionsSpencer D Dorn
Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7080, USA
Gastroenterology 137:518-24, 524.e1-2. 2009..We sought to determine the relationship between promotion of tegaserod and the number of office visits for abdominal pain, constipation, and bloating; diagnoses of irritable bowel syndrome (IBS); and tegaserod prescriptions... - Factors associated with potentially inappropriate drug utilization in a sample of rural community-dwelling older adultsSusan J Blalock
School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599 7360, USA
Am J Geriatr Pharmacother 3:168-79. 2005..The Beers criteria are often used to identify such medications. Past research has documented that use of Beers drugs is common among older adults... - Discontinuation rates for selective serotonin reuptake inhibitors and other second-generation antidepressants in outpatients with major depressive disorder: a systematic review and meta-analysisGerald Gartlehner
Cecil G Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, NC 27599, USA
Int Clin Psychopharmacol 20:59-69. 2005.... - Evaluation of product switching after a state Medicaid program began covering loratadine OTC 1 year after market availabilityTroy K Trygstad
Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, C B 7360, University of North Carolina, Chapel Hill, NC 27599 7360, USA
J Manag Care Pharm 12:108-20. 2006..The objective of this study was to determine patterns of LSA utilization in relation to changes in OTC availability and Medicaid coverage policy and to assess the rate of product switching associated with these policies... - Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomesGerald Gartlehner
Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Ann Fam Med 4:253-62. 2006..We wanted to review systematically the efficacy, effectiveness, and safety of inhaled corticosteroids with respect to health outcomes in patients with chronic obstructive pulmonary disease (COPD)... - The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: a systematic review and metaanalysisGerald Gartlehner
Cecil G Sheps Center for Health Services, and School of Public Health, Health Policy and Administration, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
J Rheumatol 33:2398-408. 2006..In addition, dosing regimens and routes of administration differ substantially among biologics. In a systematic review, we assessed the comparative efficacy and safety of biologic agents for RA... - A simple and valid tool distinguished efficacy from effectiveness studiesGerald Gartlehner
University of North Carolina at Chapel Hill, Cecil G Sheps Center for Health Services Research, NC 27599, USA
J Clin Epidemiol 59:1040-8. 2006..To propose and test a simple instrument based on seven criteria of study design to distinguish effectiveness (pragmatic) from efficacy (explanatory) trials... - Biologics for the treatment of juvenile idiopathic arthritis: a systematic review and critical analysis of the evidenceGerald Gartlehner
Ludwig Boltzmann Institute for Health Technology Assessments, Garnisongasse 7 20, 1090, Vienna, Austria
Clin Rheumatol 27:67-76. 2008..Clinicians have to be aware of the lack of evidence supporting a long-term net benefit when considering biologics for patients with JIA... - Risk of adverse gastrointestinal events from inhaled corticosteroidsRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, School of Pharmacy, Chapel Hill, North Carolina 27599 7360, USA
Pharmacotherapy 28:1325-34. 2008..To determine whether patients prescribed inhaled corticosteroids are at risk for adverse gastrointestinal effects... - Methodology of a pilot study to improve the quality of medication use in older adults: Enhancing Quality in Psychiatry Using Pharmacists (EQUIPP)Mary T Roth
Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7573, USA
Am J Geriatr Pharmacother 7:362-72. 2009.... - Effect of ropinirole on sleep outcomes in patients with restless legs syndrome: meta-analysis of pooled individual patient data from randomized controlled trialsRichard A Hansen
Division of Pharmaceutical Outcomes and Policy, Center for Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599 7360, USA
Pharmacotherapy 29:255-62. 2009.... - Systematic review: comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritisKatrina E Donahue
University of North Carolina and Cecil G Sheps Center for Health Services Research, Chapel Hill, North Carolina 27599, USA
Ann Intern Med 148:124-34. 2008..The comparative effectiveness of rheumatoid arthritis therapies is uncertain... - Selected characteristics of senior citizens prescription drug payment and procurement in 1998 and 2001Jon C Schommer
University of Minnesota College of Pharmacy, 308 Harvard St, SE, Minneapolis, MN 55455, USA
J Manag Care Pharm 9:408-15. 2003..The U.S. legislature is considering Medicare coverage for prescription drugs and the use of managed care approaches for containing costs associated with senior citizens. prescription drug therapy... - The study of direct-to-consumer advertising for prescription drugsJon C Schommer
University of Minnesota, College of Pharmacy, 308 Harvard Street, SE, Minneapolis, MN 55455, USA
Res Social Adm Pharm 1:348-68. 2005.... - Distinguishing characteristics of patients who seek more information or request a prescription in response to direct-to-consumer advertisementsJon C Schommer
University of Minnesota, College of Pharmacy, 308 Harvard Street, SE, Minneapolis, MN 55455, USA
Res Social Adm Pharm 1:231-50. 2005..The objective of this study was to examine demographic and psychographic profiles of individuals who sought additional information or requested a prescription drug based on a direct-to-consumer advertisement... - Resorptive drug use among community-dwelling women in MinnesotaJoel F Farley
Department of Pharmaceutical Care and Health Systems, College of Pharmacy, University of Minnesota, Minneapolis 55455, USA
Am J Health Syst Pharm 61:1577-85. 2004..The frequency of and factors associated with the use of resorptive medications among community-dwelling women age 45 years or older in Minnesota were studied... - Osteoporosis beliefs and antiresorptive medication useRichard R Cline
College of Pharmacy, University of Minnesota, 308 Harvard St, SE, Minneapolis, MN 55455, USA
Maturitas 50:196-208. 2005.... - Effect of second-generation antidepressants on mania- and depression-related visits in adults with bipolar disorder: a retrospective studyAlex Z Fu
Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, OH, USA
Value Health 10:128-36. 2007..To assess the effect of second-generation antidepressants on mania-related and depression-related office visits for adults with bipolar disorder... - Treating the physical symptoms of depression with second-generation antidepressants: a systematic review and metaanalysisErin E Krebs
Center on Implementing Evidence Based Practice, Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA
Psychosomatics 49:191-8. 2008..Approximately two-thirds of patients with depression experience physical pain symptoms. Coexisting pain complicates the treatment of depression and is associated with worse depression outcomes...