Research Topics
| GREGORY HANNASummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Error-related negativity and tic history in pediatric obsessive-compulsive disorderGregory L Hanna
University of Michigan, USA
J Am Acad Child Adolesc Psychiatry 51:902-10. 2012..However, the relation of the ERN to comorbid tic disorders has not been examined in patients with OCD. This study compared ERN amplitudes in patients with tic-related OCD, patients with non-tic-related OCD, and healthy controls...
Major depressive disorder in a family study of obsessive-compulsive disorder with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Depress Anxiety 28:501-8. 2011..This study examined the comorbidity of obsessive-compulsive disorder (OCD) with major depressive disorder (MDD) in a family study of OCD with pediatric probands...
Evidence for a susceptibility locus on chromosome 10p15 in early-onset obsessive-compulsive disorderGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
Biol Psychiatry 62:856-62. 2007..The goal of this study was to identify chromosomal regions likely to contain susceptibility loci for obsessive-compulsive disorder (OCD)...
Separation anxiety in children and adolescents treated with risperidoneG L Hanna
Department of Psychiatry, Child and Adolescent Psychiatric Hospital, University of Michigan Health System, Ann Arbor 48109 0390, USA
J Child Adolesc Psychopharmacol 9:277-83. 1999..We discuss the diagnostic issues concerning separation anxiety induced by antipsychotic medications, and suggest that the atypical antipsychotics may differ in their tendency to elicit separation anxiety...
Complex segregation analysis of obsessive-compulsive disorder in families with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, 48109, USA
Hum Hered 60:1-9. 2005..The purpose of this study was to assess the mode of inheritance for obsessive-compulsive disorder (OCD) in families ascertained through pediatric probands...
Familial and sporadic subtypes of early-onset Obsessive-Compulsive disorderGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
Biol Psychiatry 57:895-900. 2005..This study was done to determine whether there are differences between familial and sporadic probands with early-onset OCD in obsessive-compulsive (OC) symptom categories and comorbid psychiatric diagnoses...
A family study of obsessive-compulsive disorder with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0390, USA
Am J Med Genet B Neuropsychiatr Genet 134:13-9. 2005..1% vs. 20.9%, P < 0.01). The results provide further evidence that early-onset OCD is highly familial and suggest that two clinical variables are associated with its familial aggregation...
Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0390, USA
Am J Med Genet 114:541-52. 2002..73 on 19q. The maximum multipoint LOD score with a recessive model was 1.40 on 6p. The results provide suggestive evidence for linkage on 9p and identify regions requiring further study with much larger samples...
Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorderDiane E Dickel
Institute of Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA
Biol Psychiatry 61:322-9. 2007..Early-onset OCD is a more familial form of the disorder...
The Obsessive Compulsive Scale of the Child Behavior Checklist predicts obsessive-compulsive disorder: a receiver operating characteristic curve analysisJames J Hudziak
Department of Psychiatry, University of Vermont, Given B229, Burlington, VT 05405, USA
J Child Psychol Psychiatry 47:160-6. 2006....
Group behavioral therapy for adolescents with tic-related and non-tic-related obsessive-compulsive disorderJoseph A Himle
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0840, USA
Depress Anxiety 17:73-7. 2003..Outcomes were similar for subjects with tic-related and non-tic-related OCD. These preliminary results suggest that the presence of comorbid tic disorders may not attenuate response to behavioral group treatment among adolescents...
Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholismScott F Stoltenberg
University of Michigan Addiction Research Center and Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48108, USA
Am J Med Genet 114:230-4. 2002..The results of this pilot study suggest that further work should examine the mediation of the genetic effects on personality traits by biochemical measures and their moderation by gender...
Videoconferencing-based cognitive-behavioral therapy for obsessive-compulsive disorderJoseph A Himle
The University of Michigan Department of Psychiatry, 2101 Commonwealth Ave, Ann Arbor, MI 48105, USA
Behav Res Ther 44:1821-9. 2006..This pilot study suggests that videoconferencing-based CBT is a promising method to bring appropriate treatment to thousands who live far distances from well-trained therapists...
Major depressive disorder in adolescents: family psychiatric history predicts severe behavioral disinhibitionCheryl A King
University of Michigan, USA
J Affect Disord 90:111-21. 2006..This study was designed to determine whether family psychiatric histories differ between groups of MDD adolescents defined by the presence or absence of severe behavioral disinhibition...
Obsessive-compulsive disorder among African Americans and blacks of Caribbean descent: results from the National Survey of American LifeJoseph A Himle
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 5763, USA
Depress Anxiety 25:993-1005. 2008..This is the first comprehensive examination of OCD among African Americans and blacks of Caribbean descent...
Family-Based Association Testing of OCD-associated SNPs of SLC1A1 in an autism sampleCamille W Brune
Institute for Juvenile Research, Department of Psychiatry, University of Illinois Chicago, Chicago, Illinois 60608, USA
Autism Res 1:108-13. 2008..01). The G allele was also undertransmitted in the T-G haplotype under the recessive model (Z=-2.41, P=0.02). Both findings were also observed in the male-only sample. However, they did not withstand correction for multiple comparisons...
Obsessive-compulsive disorder with and without tics in a clinical sample of children and adolescentsGregory L Hanna
Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of Michigan Health System, University of Michigan, Ann Arbor, Michigan 48109-0390, USA
Depress Anxiety 16:59-63. 2002..The results indicate that tic-related OCD may be differentiated from non-tic-related OCD early in life by the presence or absence of certain compulsive symptoms...
Separation anxiety disorder and school refusal in children and adolescentsGregory L Hanna
Section of Child and Adolescent Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan, USA
Pediatr Rev 27:56-63. 2006
Practice guideline for the treatment of patients with obsessive-compulsive disorderLorrin M Koran
Am J Psychiatry 164:5-53. 2007
Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorderDiane E Dickel
Department of Human Genetics, University of Chicago, Chicago, IL, USA
Arch Gen Psychiatry 63:778-85. 2006....
Elevated thyroid indices in children and adolescents with obsessive-compulsive disorder: effects of clomipramine treatmentJames T McCracken
UCLA Neuropsychiatric Institute, Los Angeles, California 90024 1759, USA
J Child Adolesc Psychopharmacol 15:581-7. 2005....
Research Grants
- MOLECULAR GENETICS OF OBSESSIVE COMPULSIVE DISORDERGREGORY HANNA; Fiscal Year: 2001..Parametric and nonparametric linkage analyses will be performed. Once evidence for linkage between early-onset OCD and a genetic marker is found, more precise gene localization will be pursued. ..
- 2/3-Brain Chemistry and Genetics in Pediatric Obsessive-Compulsive DisorderGregory L Hanna; Fiscal Year: 2010..By combining brain imaging and genetics, as we do in this proposal, we can better understand the biology of pediatric OCD and, in turn, develop more effective treatments for this severe form of childhood psychopathology. ..
