Renzhi Han

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint The effect of the PKC inhibitor calphostin C and the PKC agonist phorbol 12-myristate 13-acetate on regulation of cytosolic Ca(2+) in mammalian skeletal muscle cells
    Renzhi Han
    Physiology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Toxicol Appl Pharmacol 212:247-55. 2006
  2. ncbi request reprint Measurement of sub-membrane [Ca2+] in adult myofibers and cytosolic [Ca2+] in myotubes from normal and mdx mice using the Ca2+ indicator FFP-18
    Renzhi Han
    School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Cell Calcium 40:299-307. 2006
  3. ncbi request reprint Effect of indomethacin on force responses and sarcoplasmic reticulum function in skinned skeletal muscle fibers and cytosolic [Ca2+] in myotubes
    Renzhi Han
    School of Biomedical and Chemical Studies, The University of Western Australia, Crawley, Australia
    Am J Physiol Cell Physiol 285:C881-90. 2003
  4. pmc The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat
    Renzhi Han
    School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Australia
    Br J Pharmacol 138:417-26. 2003
  5. ncbi request reprint Thapsigargin modulates osteoclastogenesis through the regulation of RANKL-induced signaling pathways and reactive oxygen species production
    Kirk H M Yip
    Molecular Orthopaedic Laboratory, School of Surgery and Pathology, and Western Australian Institute for Medical Research, Nedlands, WA 6009, Australia
    J Bone Miner Res 20:1462-71. 2005
  6. ncbi request reprint Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors
    Yaowanuj Kirilak
    School of Surgery and Pathology Orthopaedics, The University of Western Australia, Crawley WA 6009, Australia
    Int J Mol Med 17:551-8. 2006
  7. pmc Dysferlin and muscle membrane repair
    Renzhi Han
    Howard Hughes Medical Institute, Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
    Curr Opin Cell Biol 19:409-16. 2007
  8. ncbi request reprint Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts
    Jiake Xu
    Molecular Orthopaedic Laboratory, School of Surgery and Pathology, University of Western Australia, Nedlands WA, Australia
    J Cell Physiol 202:554-62. 2005
  9. pmc Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury
    Renzhi Han
    Howard Hughes Medical Institute, The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA
    J Clin Invest 117:1805-13. 2007

Collaborators

Detail Information

Publications9

  1. ncbi request reprint The effect of the PKC inhibitor calphostin C and the PKC agonist phorbol 12-myristate 13-acetate on regulation of cytosolic Ca(2+) in mammalian skeletal muscle cells
    Renzhi Han
    Physiology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Toxicol Appl Pharmacol 212:247-55. 2006
    ..These results indicate that PKC plays a role in modulation of SR function in skeletal muscle cells, and the PKC inhibitor CC may alter Ca(2+) handling via both PKC-dependent and PKC-independent pathways...
  2. ncbi request reprint Measurement of sub-membrane [Ca2+] in adult myofibers and cytosolic [Ca2+] in myotubes from normal and mdx mice using the Ca2+ indicator FFP-18
    Renzhi Han
    School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Cell Calcium 40:299-307. 2006
    ..This study suggests that the sub-sarcolemmal Ca(2+) homeostasis is well maintained in isolated adult mdx myofibers and also further supports the hypothesis that cytosolic Ca(2+) handling is compromised in mdx myotubes...
  3. ncbi request reprint Effect of indomethacin on force responses and sarcoplasmic reticulum function in skinned skeletal muscle fibers and cytosolic [Ca2+] in myotubes
    Renzhi Han
    School of Biomedical and Chemical Studies, The University of Western Australia, Crawley, Australia
    Am J Physiol Cell Physiol 285:C881-90. 2003
    ..These data suggest that intracellular PLA2 may be an important modulator of ECC in skeletal muscle...
  4. pmc The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat
    Renzhi Han
    School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Australia
    Br J Pharmacol 138:417-26. 2003
    ..Chelerythrine may be an important pharmacological probe for examining the mechanisms of contraction-induced muscle injury...
  5. ncbi request reprint Thapsigargin modulates osteoclastogenesis through the regulation of RANKL-induced signaling pathways and reactive oxygen species production
    Kirk H M Yip
    Molecular Orthopaedic Laboratory, School of Surgery and Pathology, and Western Australian Institute for Medical Research, Nedlands, WA 6009, Australia
    J Bone Miner Res 20:1462-71. 2005
    ..In this study, we showed a biphasic effect of TG on osteoclast formation and apoptosis through the regulation of ROS production, caspase-3 activity, cytosolic Ca2+, and RANKL-induced activation of NF-kappaB and AP-1 activities...
  6. ncbi request reprint Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors
    Yaowanuj Kirilak
    School of Surgery and Pathology Orthopaedics, The University of Western Australia, Crawley WA 6009, Australia
    Int J Mol Med 17:551-8. 2006
    ..Together, these data demonstrate that FS supports both the migration and proliferation of human chondrocytes. We propose that these effects are mediated, at least in part, via thrombin-induced PAR-1 signalling in human chondrocytes...
  7. pmc Dysferlin and muscle membrane repair
    Renzhi Han
    Howard Hughes Medical Institute, Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
    Curr Opin Cell Biol 19:409-16. 2007
    ..Future research on dysferlin and its interacting partners will enhance the understanding of this important process and provide novel avenues to potential therapies...
  8. ncbi request reprint Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts
    Jiake Xu
    Molecular Orthopaedic Laboratory, School of Surgery and Pathology, University of Western Australia, Nedlands WA, Australia
    J Cell Physiol 202:554-62. 2005
    ..Our data imply a cross talk mechanism of extracellular Ca2+ on osteoclast survival through the regulation of RANKL...
  9. pmc Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury
    Renzhi Han
    Howard Hughes Medical Institute, The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA
    J Clin Invest 117:1805-13. 2007
    ..Thus, our study establishes what we believe is a novel mechanism underlying the cardiomyopathy that results from a defective membrane repair in the absence of dysferlin...