Research TopicsSpecies | Steven HamiltonSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Analysis of four DLX homeobox genes in autistic probandsSteven P Hamilton
Department of Psychiatry, University of California, San Francisco, CA, USA
BMC Genet 6:52. 2005..We investigated the role that sequence variants in DLX genes play in autism by in-depth resequencing of these genes in 161 autism probands from the AGRE collection...
Investigation of polymorphisms in the CREM gene in panic disorderSteven P Hamilton
Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Am J Med Genet B Neuropsychiatr Genet 126:111-5. 2004..These findings provide little additional evidence for a susceptibility locus for panic disorder either within the CREM gene or in a nearby region of chromosome 10p11 in our sample...- A family with X-linked anophthalmia: exclusion of SOX3 as a candidate geneAnne Slavotinek
Department of Pediatrics, Division of Clinical Genetics, University of California, San Francisco, California 94143 0748, USA
Am J Med Genet A 138:89-94. 2005..We have improved the definition of the phenotype in males with anophthalmia linked to the ANOP1 locus, as microcephaly, ocular colobomas, and severe renal malformations have not been described in families linked to ANOP1... - Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22Steven P Hamilton
Department of Psychiatry, College of Physicians and Surgeons at Columbia University, New York, NY, USA
Biol Psychiatry 51:591-601. 2002..CONCLUSIONS: Our findings provide strong evidence for a susceptibility locus for panic disorder either within the COMT gene or in a nearby region of chromosome 22... 
Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depressionJie Huang
Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, and Psychiatric Genetics Program in Mood and Anxiety Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Psychiatry 167:1254-63. 2010..The purpose of this study was to apply genomewide association study (GWAS) analysis to address the specificity of genetic effects on these disorders...- A third-pass genome scan in panic disorder: evidence for multiple susceptibility lociAbby J Fyer
Department of Psychiatry, College of Physicians and Surgeons, Columbia University and New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 60:388-401. 2006..Panic disorder (PD) is a common illness with a definite but "complex" genetic contribution and estimated heritability of 30-46%... - Further genetic evidence for a panic disorder syndrome mapping to chromosome 13qSteven P Hamilton
Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Proc Natl Acad Sci U S A 100:2550-5. 2003.... - Resequencing of serotonin-related genes and association of tagging SNPs to citalopram responseEric J Peters
Department of Psychiatry and Institute for Human Genetics, University of California, San Francisco, CA, USA
Pharmacogenet Genomics 19:1-10. 2009..It appears that genetic variation in these five genes has a marginal effect on response to citalopram, although a previously observed association was supported and awaits replication in an independent sample... - Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorderHolly A Garriock
Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
Am J Psychiatry 167:565-73. 2010.... - A genomewide association study of citalopram response in major depressive disorderHolly A Garriock
Department of Psychiatry and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0984, USA
Biol Psychiatry 67:133-8. 2010..We have carried out a genomewide association study to determine whether common DNA variation influences antidepressant response... - Analysis of association between the serotonin transporter and antidepressant response in a large clinical sampleJeffrey B Kraft
Department of Psychiatry and Center for Human Genetics, University of California, San Francisco, California 94143 0984, USA
Biol Psychiatry 61:734-42. 2007..We sought to replicate our previous findings that SLC6A4 is associated with response to a selective serotonin reuptake inhibitor (SSRI) in a large case-control study... - Sequence analysis of the serotonin transporter and associations with antidepressant responseJeffrey B Kraft
Department of Psychiatry and Center for Human Genetics, University of California San Francisco, 401 Parnassus Avenue, San Francisco, CA 94143 0984, USA
Biol Psychiatry 58:374-81. 2005..We sought to test further the hypothesis that SLC6A4 is associated with SSRI response by resequencing this gene in subjects with major depression... - Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor and panic disorderSteven P Hamilton
Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, New York City, NY 10032, USA
Neuropsychopharmacology 29:558-65. 2004.... - Large-scale SNP genotyping with canine buccal swab DNAMelanie Lee Chang
Department of Psychiatry and Institute for Human Genetics, Langley Porter Psychiatric Institute, University of California San Francisco, Box 0984 NGL, San Francisco, CA 94143 0984, USA
J Hered 98:428-37. 2007..These results demonstrate the suitability of amplified canine buccal samples for high-throughput multiplex genotyping and confirm extensive LD in the dog... - Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorderLaura M Hodges
Department of Psychiatry, Institute for Human Genetics, University of California, San Francisco, 94143 0984, USA
Am J Med Genet B Neuropsychiatr Genet 150:65-73. 2009..Further exploration of the GRP and TACR1 findings in large case-control PD samples may provide more definitive evidence implicating these loci in the genetic etiology of PD... - Array-based whole-genome survey of dog saliva DNA yields high quality SNP dataJennifer S Yokoyama
Department of Psychiatry and Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA
PLoS ONE 5:e10809. 2010..We thus investigated an animal-based saliva collection method for ease of use and quality of DNA obtained and tested the performance of saliva-extracted canine DNA on genome-wide genotyping arrays... - Early-onset fearful panic attack: a possible prodrome of early-onset severe psychopathologyRenee D Goodwin
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 43, New York, NY 10032, USA
Compr Psychiatry 43:22-7. 2002..Replication of these findings in other epidemiologic and clinical samples is needed... - Schizophrenia candidate genes: are we really coming up blank?Steven P Hamilton
Am J Psychiatry 165:420-3. 2008 - Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sampleEric J Peters
Department of Psychiatry and Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 3:e1872. 2008..We sought to determine whether clinical response or tolerance to the Selective Serotonin Reuptake Inhibitor (SSRI) citalopram is associated with genetic polymorphisms in potentially relevant pharmacokinetic enzymes... - Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association studyHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Breast Cancer Res 7:R71-81. 2005....
Research Grants
- Pharmacogenomics of Antidepressant ResponseSteven Hamilton; Fiscal Year: 2007..These findings could provide steps toward our ability to define clinically useful genetic predictors of pharmacological treatment and apply them to patient populations. ..
- Genetic Determinants of COMT ExpressionSteven Hamilton; Fiscal Year: 2007..This in vitro work may be useful for the understanding of the genetic contribution of COMT to disease susceptibility, particularly with regard to the cis regulation of the COMT locus. ..