R L Hamilton

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint The molecular biology of ependymomas
    R L Hamilton
    Department of Pathology, University of Pittsburgh, PA, USA
    Brain Pathol 7:807-22. 1997
  2. ncbi request reprint Alzheimer disease pathology in amyotrophic lateral sclerosis
    Ronald L Hamilton
    A 506, Presbyterian University Hospital, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Acta Neuropathol 107:515-22. 2004
  3. ncbi request reprint Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry
    R L Hamilton
    University of Pittsburgh School of Medicine, Department of Pathology, PA, USA
    Brain Pathol 10:378-84. 2000
  4. ncbi request reprint Psychotic symptoms in Alzheimer's disease are not associated with more severe neuropathologic features
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Int Psychogeriatr 12:547-58. 2000
  5. ncbi request reprint The relationship between TP53 mutations and overexpression of p53 and prognosis in malignant gliomas of childhood
    I F Pollack
    Department of Neurosurgery, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    Cancer Res 57:304-9. 1997
  6. pmc Lewy-like aggregation of α-synuclein reduces protein phosphatase 2A activity in vitro and in vivo
    J Wu
    Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Neuroscience 207:288-97. 2012
  7. ncbi request reprint Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis
    R A Sweet
    University of Pittsburgh, Division of Geriatrics and Neuropsychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Neurol 58:466-72. 2001
  8. ncbi request reprint [Recent advances in the neuropathological evaluation of Alzheimer's disease: the importance of alpha-synuclein]
    R L Hamilton
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Rev Neurol 35:765-7. 2002
  9. ncbi request reprint 1p/19q testing has no significance in the workup of glioblastomas
    K H Clark
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropathol Appl Neurobiol 39:706-17. 2013
  10. ncbi request reprint Lewy bodies in the amygdala increase risk for major depression in subjects with Alzheimer disease
    O L Lopez
    Alzheimer s Disease Research Center, Department of Neurology, University of Pittsburgh School of Medicine, PA, USA
    Neurology 67:660-5. 2006

Detail Information

Publications55

  1. ncbi request reprint The molecular biology of ependymomas
    R L Hamilton
    Department of Pathology, University of Pittsburgh, PA, USA
    Brain Pathol 7:807-22. 1997
    ..Herein we review potential oncological markers in ependymomas that have been identified to date and highlight the limitations of our current knowledge as a basis for defining areas for future investigation...
  2. ncbi request reprint Alzheimer disease pathology in amyotrophic lateral sclerosis
    Ronald L Hamilton
    A 506, Presbyterian University Hospital, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Acta Neuropathol 107:515-22. 2004
    ..In conclusion, we found that approximately 30% of ALS cases with dementia have AD and that some ALS cases without frank dementia have significant AD pathology...
  3. ncbi request reprint Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry
    R L Hamilton
    University of Pittsburgh School of Medicine, Department of Pathology, PA, USA
    Brain Pathol 10:378-84. 2000
    ..In conclusion, this study found that AS IHC detects LBs in the majority of sporadic AD cases and that the amygdala is the most commonly affected region...
  4. ncbi request reprint Psychotic symptoms in Alzheimer's disease are not associated with more severe neuropathologic features
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Int Psychogeriatr 12:547-58. 2000
    ..The association of AD+P with a more rapidly progressive course of AD appears to be mediated by a neuropathologic process other than increased severity of plaque and tangle formation...
  5. ncbi request reprint The relationship between TP53 mutations and overexpression of p53 and prognosis in malignant gliomas of childhood
    I F Pollack
    Department of Neurosurgery, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    Cancer Res 57:304-9. 1997
    ..These results indicate that p53 mutation and expression status may be associated with prognosis in childhood malignant gliomas, and thus may provide a basis for stratifying patients biologically in future malignant glioma studies...
  6. pmc Lewy-like aggregation of α-synuclein reduces protein phosphatase 2A activity in vitro and in vivo
    J Wu
    Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Neuroscience 207:288-97. 2012
    ....
  7. ncbi request reprint Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis
    R A Sweet
    University of Pittsburgh, Division of Geriatrics and Neuropsychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Neurol 58:466-72. 2001
    ..Lewy bodies (LB) are present in at least 20% to 30% of persons with Alzheimer disease (AD) and contribute to the risk of psychosis and to excess cognitive burden...
  8. ncbi request reprint [Recent advances in the neuropathological evaluation of Alzheimer's disease: the importance of alpha-synuclein]
    R L Hamilton
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Rev Neurol 35:765-7. 2002
    ..These can be detected by a synuclein immunohistochemistry in most of the sporadic cases of AD and is most frequently detected in the amygdala...
  9. ncbi request reprint 1p/19q testing has no significance in the workup of glioblastomas
    K H Clark
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropathol Appl Neurobiol 39:706-17. 2013
    ..To determine whether testing for isolated 1p or 19q losses, or as a codeletion, has any significance in the workup of glioblastomas (GBMs)...
  10. ncbi request reprint Lewy bodies in the amygdala increase risk for major depression in subjects with Alzheimer disease
    O L Lopez
    Alzheimer s Disease Research Center, Department of Neurology, University of Pittsburgh School of Medicine, PA, USA
    Neurology 67:660-5. 2006
    ..To determine the relationship between major depression and the presence of Lewy bodies (LBs) in patients with Alzheimer disease (AD)...
  11. ncbi request reprint Congenital reactive myofibroblastic tumor of the petrous bone: case report
    I F Pollack
    Department of Neurosurgery, Children s Hospital of Pittsburgh, and the Center for Cranial Base Surgery, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    Neurosurgery 48:430-5. 2001
    ..We present a case of a congenital reactive myofibroblastic tumor of the petrous bone (i.e., cranial fasciitis) that was successfully treated with surgical excision...
  12. ncbi request reprint Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort
    I F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 61:7404-7. 2001
    ..The association between age and frequency of TP53 mutations among pediatric malignant gliomas indicates the probable existence of two distinct pathways of molecular tumorigenesis in younger versus older children...
  13. ncbi request reprint Blood-brain barrier disruption in simian immunodeficiency virus encephalitis
    M K Luabeya
    Department of Pathology Division of Neuropathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Neuropathol Appl Neurobiol 26:454-62. 2000
    ....
  14. ncbi request reprint [The other dementias: the neuropathology of the non-Alzheimer's disease dementias]
    R L Hamilton
    Departmento de Patologia, Servicio de Neuropatología, Prebitarian Univeristy Hospital, Pittsburgh, PA 15213, USA
    Rev Neurol 37:130-9. 2003
    ..The neuropathological criteria for the diagnosis of these non AD dementia disorders will be reviewed...
  15. pmc Right prosubiculum amyloid plaque density correlates with anosognosia in Alzheimer's disease
    G A Marshall
    Department of Neurology, University of Pittsburgh, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 75:1396-400. 2004
    ..There is an association between impaired awareness and frontal-executive cognitive deficits. Anosognosia is also correlated with decreased metabolism in the right hemisphere, particularly in frontal lobe regions...
  16. doi request reprint Reversible encephalopathy after cardiac transplantation: histologic evidence of endothelial activation, T-cell specific trafficking, and vascular endothelial growth factor expression
    C Horbinski
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    AJNR Am J Neuroradiol 30:588-90. 2009
    ....
  17. ncbi request reprint Brain membrane phospholipid alterations in Alzheimer's disease
    J W Pettegrew
    Department of Psychiatry School of Medicine, University of Pittsburgh, Pennsylvania, USA
    Neurochem Res 26:771-82. 2001
    ..The present findings could possibly contribute to an abnormal membrane repair in AD brains which ultimately results in synaptic loss and the aggregation of A beta peptide...
  18. ncbi request reprint Sudden death from fulminant acute cerebellitis
    E I Levy
    Department of Neurosurgery, Children's Hospital of Pittsburgh, PA, USA
    Pediatr Neurosurg 35:24-8. 2001
    ..Histopathologic correlation is provided. The etiologies, clinical course, therapeutic interventions and postmortem evaluation of this potentially life-threatening condition are briefly reviewed...
  19. ncbi request reprint Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury
    R S Clark
    Departments of Anesthesiology and Critical Care Medicine, Safar Center for Resuscitation Reseach, Pittsburgh, PA 15260, USA
    FASEB J 13:813-21. 1999
    ..These findings are the first to demonstrate that programmed cell death occurs in human brain after acute injury, and identify potential pharmacological and molecular targets for the treatment of human head injury...
  20. pmc Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
    Milos D Ikonomovic
    Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Brain 131:1630-45. 2008
    ..The strong direct correlation of in vivo PiB retention with region-matched quantitative analyses of Abeta plaques in the same subject supports the validity of PiB-PET imaging as a method for in vivo evaluation of Abeta plaque burden...
  21. ncbi request reprint The characterization of tumor apoptosis after experimental radiosurgery
    Timothy F Witham
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Stereotact Funct Neurosurg 83:17-24. 2005
    ..The time course of this radiobiologic phenomenon begins at approximately 6 h following radiosurgery, continues up to 48 h, and begins to decline by 72 h...
  22. ncbi request reprint Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex
    Purnima P Desai
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Neurobiol Dis 20:574-82. 2005
    ..Elevated apoD in AD brain may influence Abeta aggregation, or facilitate phagocytosis and transport of Abeta fibrils from plaques to cerebral vasculature...
  23. pmc Neuronal intranuclear inclusion disease without polyglutamine inclusions in a child
    Kathryn McFadden
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Neuropathol Exp Neurol 64:545-52. 2005
    ..We suggest that juvenile NIID is a spinocerebellar brainstem ataxic disease possibly related to an abnormality in SUMOylation...
  24. pmc EphA2 as a glioma-associated antigen: a novel target for glioma vaccines
    Manabu Hatano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
    Neoplasia 7:717-22. 2005
    ..Taken together, these data suggest that EphA2883-891 may be an attractive antigen epitope for molecularly targeted glioma vaccines...
  25. ncbi request reprint Plasmalemmal vesicle associated protein-1 is a novel marker implicated in brain tumor angiogenesis
    Eleanor B Carson-Walter
    Department of Neurosurgery, University of Pittsburgh, PA 15213, USA
    Clin Cancer Res 11:7643-50. 2005
    ..We sought to further characterize the expression pattern of PV-1 in human brain tumors and interrogate its role in brain tumor angiogenesis...
  26. ncbi request reprint O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Oncol 24:3431-7. 2006
    ..Epigenetic silencing of MGMT has been associated with prolonged survival in adults with malignant gliomas, although the association between MGMT expression status and outcome in pediatric malignant gliomas has not been defined...
  27. ncbi request reprint Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease
    Pravat K Mandal
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neurochem Res 31:1153-62. 2006
    ..To the best of our knowledge, it is the first report using multidimensional NMR spectroscopy that elucidates molecular interactions between Abeta and alpha-Syn which may lead to onset of DLB...
  28. pmc Expression of Nrf2 in neurodegenerative diseases
    Chenere P Ramsey
    Department of Pathology, University of Pennsylvania, School of Dental Medicine, Philadelphia, Pennsylvania, USA
    J Neuropathol Exp Neurol 66:75-85. 2007
    ..In PD, nuclear localization of Nrf2 is strongly induced, but this response may be insufficient to protect neurons from degeneration...
  29. pmc Tumor cells from ultrasonic aspirations of glioblastomas migrate and form spheres with radial outgrowth
    Marie E Beckner
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Cancer Lett 255:135-44. 2007
    ..Cultures were maintained for more than six weeks without fibroblastic overgrowth. Our observations show that ultrasonically aspirated specimens contain cells useful for studies of tumor migration and growth of tumorspheres...
  30. pmc Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas
    Hideho Okada
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Transl Med 5:67. 2007
    ..The prognosis for malignant gliomas remains dismal. We addressed the safety, feasibility and preliminary clinical activity of the vaccinations using autologous glioma cells and interleukin (IL)-4 gene transfected fibroblasts...
  31. ncbi request reprint Loss of heterozygosity analysis of benign, atypical, and anaplastic meningiomas
    John Y K Lee
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 55:1163-73. 2004
    ..Allelic loss at additional chromosomal loci is associated with atypia and anaplasia in meningiomas. The pattern of allelic loss or loss of heterozygosity (LOH) follows a nonrandom, multistep pattern...
  32. ncbi request reprint Neuropathologic correlates of late-onset major depression
    Robert A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Neuropsychopharmacology 29:2242-50. 2004
    ..These preliminary findings suggest that AD is the predominant neuropathologic condition in LLMD subjects with dementia. Further assessment of the role of comorbid cerebrovascular disease and comorbid DLB is needed...
  33. ncbi request reprint Psychosis in Alzheimer disease: postmortem magnetic resonance spectroscopy evidence of excess neuronal and membrane phospholipid pathology
    Robert A Sweet
    Department of Psychiatry, Division of Geriatrics, Neuropsychiatry, University of Pittsburgh School of Medicine, PA, USA
    Neurobiol Aging 23:547-53. 2002
    ..Although AD+P has been inconsistently associated with more severe neuropathology, no prior studies have examined measures of neuronal and synaptic integrity...
  34. ncbi request reprint Impact of proliferation index on outcome in childhood malignant gliomas: results in a multi-institutional cohort
    Ian F Pollack
    Departments of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Neurosurgery 50:1238-44; discussion 1244-5. 2002
    ....
  35. ncbi request reprint DNA topoisomerase IIalpha predicts progression-free and overall survival in pediatric malignant non-brainstem gliomas
    Markus Bredel
    Department of General Neurosurgery, Neurocenter, University of Freiburg, Freiburg, Germany
    Int J Cancer 99:817-20. 2002
    ....
  36. ncbi request reprint The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
    William E Klunk
    Laboratory of Molecular Neuropharmacology, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 23:2086-92. 2003
    ..Finally, BTA-1 did not appear to bind significantly to common neuroreceptors or transporter sites. These data suggest that the binding of BTA-1 to AD brain is dominated by a specific interaction with Abeta amyloid deposits...
  37. ncbi request reprint Research evaluation and prospective diagnosis of dementia with Lewy bodies
    Oscar L Lopez
    Alzheimer s Disease Research Center, University of Pittsburgh, PA, USA
    Arch Neurol 59:43-6. 2002
    ..To evaluate the relative merits of recently developed criteria for dementia with Lewy bodies (DLBs) in a longitudinal study of dementia...
  38. ncbi request reprint Molecular abnormalities and correlations with tumor response and outcome in glioma patients
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Neuroimaging Clin N Am 12:627-39. 2002
    ....
  39. ncbi request reprint Association between chromosome 1p and 19q loss and outcome in pediatric malignant gliomas: results from the CCG-945 cohort
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Neurosurg 39:114-21. 2003
    ....
  40. pmc Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas
    Hideho Okada
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Neurooncol 88:245-50. 2008
    ..These results suggest that EphA2, IL-13Ralpha2 and Survivin are suitable targets for developing vaccine strategies for pediatric glioma...
  41. ncbi request reprint Microdissection-based genotyping assists discrimination of reactive gliosis from glioma
    Sydney D Finkelstein
    Department of Pathology, University of Pittsburgh Medical Center, PA, USA
    Am J Clin Pathol 121:671-8. 2004
    ..Molecular anatomic pathology opens the possibilities of molecular analysis to everyday pathology practice...
  42. ncbi request reprint Expression of p53 and prognosis in children with malignant gliomas
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    N Engl J Med 346:420-7. 2002
    ..We investigated whether mutations in the TP53 gene or the degree of expression of p53 protein in high-grade gliomas is associated with progression-free survival in children with these tumors...
  43. ncbi request reprint DNA topoisomerase IIalpha and Her-2/neu gene dosages in pediatric malignant gliomas
    Claudia Bredel
    Department of General Neurosurgery, Neurocenter, University of Freiburg, D 79106 Freiburg, Germany
    Int J Oncol 26:1187-92. 2005
    ..The observed intratumor genetic heterogeneity for TIIalpha in PMNBGs may have an impact on the relevance of TIIalpha as a biological constituent of outcome in these neoplasms...
  44. pmc Evaluation of alpha-synuclein immunohistochemical methods used by invited experts
    Thomas G Beach
    Civin Laboratory for Neuropathology, Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, AZ 85351, USA
    Acta Neuropathol 116:277-88. 2008
    ..Some methods, however, achieved relatively high sensitivities with optimized formic acid protocols combined with a hydrolytic step. One method was developed that allows high sensitivity with commercially available reagents...
  45. doi request reprint Extraventricular neurocytoma in neurofibromatosis Type 1: case report
    Ali I Raja
    Department of Neurosurgery, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    J Neurosurg Pediatr 2:63-7. 2008
    ..The importance of obtaining a biopsy in lesions that have atypical imaging features is highlighted...
  46. ncbi request reprint INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma
    Alexander R Judkins
    Department of Pathology, University of Pennsylvania School of Medicine and Children s Hospital of Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA 19104, USA
    J Neuropathol Exp Neurol 64:391-7. 2005
    ..This expression pattern seems to better define the 2 groups of tumors than does light or electron microscopy, routine immunohistochemistry, or cytogenetic analysis alone...
  47. ncbi request reprint Loss of heterozygosity reveals non-VHL allelic loss in hemangioblastomas at 22q13
    Marie E Beckner
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 35:1105-11. 2004
    ..LOH for the 22q13.2 region in HBs suggests that the loss of another tumor suppressor gene is involved in the pathogenesis of HBs in addition to VHL. Absence of LOH for glioma markers is consistent with the low-grade behavior of HBs...
  48. ncbi request reprint ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma
    Richard J Gilbertson
    Brain Tumor Program, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Clin Cancer Res 9:3620-4. 2003
    ....
  49. ncbi request reprint Redox-reactive autoantibodies in cerebrospinal fluids
    John A McIntyre
    HLA Vascular Biology Laboratory, St Francis Hospital and Health Care Centers, 1500 Albany Street, 1109, Beech Grove, IN 46107, USA
    Ann N Y Acad Sci 1109:296-302. 2007
    ..The dramatic difference in the presence of such antibodies in normal versus Alzheimer's disease (AD) suggests an important immune system dysfunction in AD...
  50. ncbi request reprint Redox-reactive autoantibodies in Alzheimer's patients' cerebrospinal fluids: preliminary studies
    John A McIntyre
    HLA Vascular Biology Laboratory, St Francis Hospital and Health Care Centers, Beech Grove, IN 46107, USA
    Autoimmunity 40:390-6. 2007
    ..These novel autoantibody observations may stimulate thoughts about additional therapeutic approaches and warrant similar studies for other neurodegenerative diseases...
  51. ncbi request reprint Microdissection genotyping of gliomas: therapeutic and prognostic considerations
    Deepak Mohan
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Mod Pathol 17:1346-58. 2004
    ....
  52. ncbi request reprint Chronic traumatic encephalopathy in a National Football League player
    Bennet I Omalu
    Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15221, USA
    Neurosurgery 57:128-34; discussion 128-34. 2005
    ..This case draws attention to the need for further studies in the cohort of retired National Football League players to elucidate the neuropathological sequelae of repeated mild traumatic brain injury in professional football...
  53. ncbi request reprint Granular cell astrocytomas show a high frequency of allelic loss but are not a genetically defined subset
    Amilcar A Castellano-Sanchez
    Department of Pathology, Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Pathol 13:185-94. 2003
    ..Instead, it appears that granular cell change occurs across genetic subsets. The high frequency of allelic loss, especially on 9p and 10q, may confer aggressive growth potential and be related to their rapid clinical progression...
  54. ncbi request reprint Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage
    Troy L Carter
    Laboratory of Neuronal Vulnerability and Aging, The Lankenau Institute for Medical Research, Jefferson Health System, Wynewood, PA 19096, USA
    Exp Neurol 187:299-309. 2004
    ....
  55. ncbi request reprint Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort
    Ian F Pollack
    Departments of Neurosurgery, University of Pittsburgh Medical Center, Children s Hospital of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 105:418-24. 2006
    ..To address this issue, we examined tumor samples from the Children's Cancer Group 945 study, a large randomized trial of treatment for childhood malignant gliomas...