M T Hamilton

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease
    Marc T Hamilton
    Department of Biomedical Sciences, University of Missouri Columbia, Columbia, MO 65211, USA
    Diabetes 56:2655-67. 2007
  2. ncbi request reprint Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation
    Marc T Hamilton
    Department of Biomedical Sciences, University of Missouri Columbia, Columbia, MO, USA
    Exerc Sport Sci Rev 32:161-6. 2004
  3. pmc Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity
    Lionel Bey
    Department of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri Columbia, MO, USA
    J Physiol 551:673-82. 2003
  4. ncbi request reprint Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity
    Theodore W Zderic
    E102 VMB, 1600 E Rollins Rd, Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri Columbia, Columbia, Missouri 65211, USA
    J Appl Physiol 100:249-57. 2006
  5. ncbi request reprint Skeletal muscle adaptation to exercise: a century of progress
    M T Hamilton
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211 0001, USA
    J Appl Physiol 88:327-31. 2000
  6. ncbi request reprint Reduced lipoprotein lipase activity in postural skeletal muscle during aging
    L Bey
    Veterinary Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri-Columbia, Columbia, Missouri 65211, USA
    J Appl Physiol 91:687-92. 2001
  7. ncbi request reprint Effect of antihypertensive agents on the development of type 2 diabetes mellitus
    Craig S Stump
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Missouri Columbia, Harry S Truman VA Medical Center, Columbia, MO 65212, USA
    Mayo Clin Proc 81:796-806. 2006
  8. ncbi request reprint Plasma triglyceride metabolism in humans and rats during aging and physical inactivity
    M T Hamilton
    Dalton Cardiovascular Research Center, University of Missouri, Columbia 65211, USA
    Int J Sport Nutr Exerc Metab 11:S97-104. 2001
  9. pmc Exercise training alters effect of high-fat feeding on the ACTH stress response in pigs
    Ryan Jankord
    Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Appl Physiol Nutr Metab 33:461-9. 2008
  10. ncbi request reprint Induction of lipoprotein lipase gene expression in 3T3-L1 preadipocytes by atorvastatin, a cholesterol- and triglyceride-lowering drug
    Lionel Bey
    Biomedical Sciences, University of Missouri Columbia, MO 65211, USA
    Pharmacology 66:51-6. 2002

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease
    Marc T Hamilton
    Department of Biomedical Sciences, University of Missouri Columbia, Columbia, MO 65211, USA
    Diabetes 56:2655-67. 2007
    ....
  2. ncbi request reprint Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation
    Marc T Hamilton
    Department of Biomedical Sciences, University of Missouri Columbia, Columbia, MO, USA
    Exerc Sport Sci Rev 32:161-6. 2004
    ..The most powerful process known to regulate lipoprotein lipase protein and activity in muscle capillaries may be initiated by inhibitory signals during physical inactivity, independent of changes in lipoprotein lipase messenger RNA...
  3. pmc Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity
    Lionel Bey
    Department of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri Columbia, MO, USA
    J Physiol 551:673-82. 2003
    ....
  4. ncbi request reprint Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity
    Theodore W Zderic
    E102 VMB, 1600 E Rollins Rd, Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri Columbia, Columbia, Missouri 65211, USA
    J Appl Physiol 100:249-57. 2006
    ..In conclusion, physical inactivity amplifies the ability of plasma lipids to suppress muscle LPL activity. The light ambulatory contractions responsible for NEAT are sufficient for mitigating these deleterious effects...
  5. ncbi request reprint Skeletal muscle adaptation to exercise: a century of progress
    M T Hamilton
    Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211 0001, USA
    J Appl Physiol 88:327-31. 2000
    ..Therefore, training studies have had an impact on setting the stage for a potential "preventive medicine reformation" in a society needing a return to a naturally active lifestyle of our ancestors...
  6. ncbi request reprint Reduced lipoprotein lipase activity in postural skeletal muscle during aging
    L Bey
    Veterinary Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri-Columbia, Columbia, Missouri 65211, USA
    J Appl Physiol 91:687-92. 2001
    ..In conclusion, LPL regulation in a non-weight-bearing muscle was not affected by aging. However, there was a pronounced reduction in LPL activity and LPL protein mass in postural muscle with aging...
  7. ncbi request reprint Effect of antihypertensive agents on the development of type 2 diabetes mellitus
    Craig S Stump
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Missouri Columbia, Harry S Truman VA Medical Center, Columbia, MO 65212, USA
    Mayo Clin Proc 81:796-806. 2006
    ..This will become even more important as the number of insulin-resistant patients with hypertension increases in parallel with the steady growth in the number of sedentary, obese, and aged persons in our population...
  8. ncbi request reprint Plasma triglyceride metabolism in humans and rats during aging and physical inactivity
    M T Hamilton
    Dalton Cardiovascular Research Center, University of Missouri, Columbia 65211, USA
    Int J Sport Nutr Exerc Metab 11:S97-104. 2001
    ..Therefore, the poor TG metabolism that is frequently associated with aging may be caused by some of the same processes that lower skeletal muscle LPL activity of young sedentary individuals...
  9. pmc Exercise training alters effect of high-fat feeding on the ACTH stress response in pigs
    Ryan Jankord
    Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Appl Physiol Nutr Metab 33:461-9. 2008
    ..Thus, the increase in FFA with high-fat feeding may explain the blunted ACTH response to an acute stressor in sedentary animals, but cannot explain the exaggerated response in exercise trained animals...
  10. ncbi request reprint Induction of lipoprotein lipase gene expression in 3T3-L1 preadipocytes by atorvastatin, a cholesterol- and triglyceride-lowering drug
    Lionel Bey
    Biomedical Sciences, University of Missouri Columbia, MO 65211, USA
    Pharmacology 66:51-6. 2002
    ..Addition of 10 micromol/l atorvastatin for 48 h resulted in a 44% increase of rat LPL promoter activity. This study demonstrates for the first time that a statin can regulate LPL gene expression transcriptionally in preadipocytes...
  11. ncbi request reprint Patterns of global gene expression in rat skeletal muscle during unloading and low-intensity ambulatory activity
    Lionel Bey
    Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri Columbia, Missouri 65211, USA
    Physiol Genomics 13:157-67. 2003
    ..This study reveals genes that are the most sensitive to loading/activity in rat skeletal muscle and indicates new targets that may initiate muscle alterations during inactivity...
  12. pmc Diaphragm unloading via controlled mechanical ventilation alters the gene expression profile
    Keith C DeRuisseau
    Department of Applied Physiology and Kinesiology, University of Florida, Room 25, Florida Gym, Gainesville, Florida 32611, USA
    Am J Respir Crit Care Med 172:1267-75. 2005
    ..However, the impact of controlled mechanical ventilation on global mRNA alterations in the diaphragm remains unknown...