K Hambidge

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorption of these minerals above physiologic requirements in young children
    Bhalchandra S Kodkany
    Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India
    J Nutr 143:1489-93. 2013
  2. doi request reprint Preconception maternal nutrition: a multi-site randomized controlled trial
    K Michael Hambidge
    University of Colorado Denver, Aurora, CO, USA
    BMC Pregnancy Childbirth 14:111. 2014
  3. pmc Fecal calprotectin levels are higher in rural than in urban Chinese infants and negatively associated with growth
    Jin rong Liu
    Department of Child and Adolescent Health Care, MOE Shanghai Key Laboratory of Children s Environmental Health, Xinhua Hospital, ShanghaiJiao Tong University, School of Medicine, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, 1665 Kongjiang Road, Shanghai 200092, China
    BMC Pediatr 12:129. 2012
  4. pmc Infant stunting is associated with short maternal stature
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado, Aurora, CO 80045, USA
    J Pediatr Gastroenterol Nutr 54:117-9. 2012
  5. pmc Communities, birth attendants and health facilities: a continuum of emergency maternal and newborn care (the Global Network's EmONC trial)
    Omrana Pasha
    Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan
    BMC Pregnancy Childbirth 10:82. 2010
  6. pmc Complementary feeding: a Global Network cluster randomized controlled trial
    Nancy F Krebs
    University of Colorado Denver, Aurora, CO, USA
    BMC Pediatr 11:4. 2011
  7. doi request reprint Physiological requirements for zinc
    K Michael Hambidge
    Pediatric Nutrition, University of Colorado Denver, Aurora, CO, USA
    Int J Vitam Nutr Res 81:72-8. 2011
  8. pmc Evaluation of meat as a first complementary food for breastfed infants: impact on iron intake
    K Michael Hambidge
    The University of Colorado Denver, Aurora, Colorado 80045, USA
    Nutr Rev 69:S57-63. 2011
  9. pmc Micronutrient bioavailability: Dietary Reference Intakes and a future perspective
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Aurora, CO 80045, USA
    Am J Clin Nutr 91:1430S-1432S. 2010
  10. pmc Zinc bioavailability and homeostasis
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Denver, CO, USA
    Am J Clin Nutr 91:1478S-1483S. 2010

Collaborators

Detail Information

Publications29

  1. pmc Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorption of these minerals above physiologic requirements in young children
    Bhalchandra S Kodkany
    Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India
    J Nutr 143:1489-93. 2013
    ....
  2. doi request reprint Preconception maternal nutrition: a multi-site randomized controlled trial
    K Michael Hambidge
    University of Colorado Denver, Aurora, CO, USA
    BMC Pregnancy Childbirth 14:111. 2014
    ....
  3. pmc Fecal calprotectin levels are higher in rural than in urban Chinese infants and negatively associated with growth
    Jin rong Liu
    Department of Child and Adolescent Health Care, MOE Shanghai Key Laboratory of Children s Environmental Health, Xinhua Hospital, ShanghaiJiao Tong University, School of Medicine, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, 1665 Kongjiang Road, Shanghai 200092, China
    BMC Pediatr 12:129. 2012
    ..To examine a possible relationship between linear growth and gut inflammation, we compared fecal calprotectin levels in 6 month old infants from poor rural vs affluent urban families...
  4. pmc Infant stunting is associated with short maternal stature
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado, Aurora, CO 80045, USA
    J Pediatr Gastroenterol Nutr 54:117-9. 2012
    ..Maternal height is independently associated with infant LAZ and stunting (LAZ <-2) at both 6 and 12 months (Pā€Š<ā€Š0.001) and with linear growth velocity from 6 to 12 months (Pā€Š=ā€Š0.0023)...
  5. pmc Communities, birth attendants and health facilities: a continuum of emergency maternal and newborn care (the Global Network's EmONC trial)
    Omrana Pasha
    Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan
    BMC Pregnancy Childbirth 10:82. 2010
    ..However, the effectiveness of emergency obstetric and neonatal care services has never been proven. Also unproven is the effectiveness of community mobilization and community birth attendant training to improve pregnancy outcomes...
  6. pmc Complementary feeding: a Global Network cluster randomized controlled trial
    Nancy F Krebs
    University of Colorado Denver, Aurora, CO, USA
    BMC Pediatr 11:4. 2011
    ..Animal source foods in particular are cited as essential to achieve micronutrient requirements. The efficacy of the recommendation for regular meat consumption, however, has not been systematically evaluated...
  7. doi request reprint Physiological requirements for zinc
    K Michael Hambidge
    Pediatric Nutrition, University of Colorado Denver, Aurora, CO, USA
    Int J Vitam Nutr Res 81:72-8. 2011
    ..The lessons to be learned from this review are discussed together with suggestions for future action by IOM as well as a constructive role for IZiNCG...
  8. pmc Evaluation of meat as a first complementary food for breastfed infants: impact on iron intake
    K Michael Hambidge
    The University of Colorado Denver, Aurora, Colorado 80045, USA
    Nutr Rev 69:S57-63. 2011
    ..These trials are presently in progress in poor communities in Guatemala, Pakistan, Zambia, Democratic Republic of the Congo, and China...
  9. pmc Micronutrient bioavailability: Dietary Reference Intakes and a future perspective
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Aurora, CO 80045, USA
    Am J Clin Nutr 91:1430S-1432S. 2010
    ..These factors, it is argued, are best considered separately from even a broad definition of bioavailability and have the potential to provide new insights into some micronutrient requirements...
  10. pmc Zinc bioavailability and homeostasis
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Denver, CO, USA
    Am J Clin Nutr 91:1478S-1483S. 2010
    ..The effects of phytate on intestinal losses of endogenous zinc merit further investigation but are probably not of the same magnitude as its inhibitory effects on absorption of exogenous zinc...
  11. ncbi request reprint Intestinal excretion of endogenous zinc in Guatemalan school children
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 137:1747-9. 2007
    ..Supported by other recent childhood data, these results suggest that the current estimates of EFZ(PR) used in the calculation of Zn requirements for children are misleadingly low...
  12. ncbi request reprint Zinc homeostasis in Malawian children consuming a high-phytate, maize-based diet
    Mark J Manary
    Department of Pediatrics, Washington University School of Medicine, St Louis, USA
    Am J Clin Nutr 75:1057-61. 2002
    ..The gastrointestinal tract plays a central role in absorbing and conserving zinc, yet it has not been carefully studied in such children...
  13. pmc Zinc absorption during late pregnancy in rural southern Ethiopia
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO, USA
    Am J Clin Nutr 84:1102-6. 2006
    ..Little is yet known about zinc absorption in late pregnancy, and no information on absorption from the total diet is available...
  14. pmc The use of dysprosium to measure endogenous zinc excretion in feces eliminates the necessity of complete fecal collections
    Leland V Miller
    University of Colorado Denver, Department of Pediatrics, Aurora, CO 80045, USA
    J Nutr 140:1524-8. 2010
    ..We found that the measurement of the sample Dy:Zn ratio was useful for selecting samples for measurement. We conclude that the Dy method of determining EFZ is a valid and less burdensome alternative to current techniques...
  15. ncbi request reprint Zinc absorption from low-phytate hybrids of maize and their wild-type isohybrids
    K Michael Hambidge
    University of Colorado Health Sciences Center, Department of Pediatrics, Section of Nutrition, Denver 80262, USA
    Am J Clin Nutr 79:1053-9. 2004
    ....
  16. pmc Dietary reference intakes for zinc may require adjustment for phytate intake based upon model predictions
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado, School of Medicine, Denver, CO 80262, USA
    J Nutr 138:2363-6. 2008
    ..4 mg Zn/d. Extrapolation of the model suggested, for example, that with 900 mg/d phytate, 100 mg dietary Zn is required to attain 6.4 mg absorbed Zn/d. Experimental studies with higher Zn intakes are required to test these predictions...
  17. ncbi request reprint Dysprosium as a nonabsorbable fecal marker in studies of zinc homeostasis
    Xiao Yang Sheng
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Clin Nutr 82:1017-23. 2005
    ..Dysprosium is a nonabsorbable rare earth element that has had successful application as a marker for fecal excretion of unabsorbed zinc...
  18. ncbi request reprint Exchangeable zinc pool size in infants is related to key variables of zinc homeostasis
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 133:1498S-501S. 2003
    ..We conclude that the amount of absorbed zinc is not tightly regulated, and that endogenous fecal zinc is dependent on and responsive to the zinc status of the organism...
  19. ncbi request reprint Zinc absorption as a function of the dose of zinc sulfate in aqueous solution
    Cuong D Tran
    Section of Nutrition, Department of Pediatrics, The University of Colorado Health Science Center, Denver, USA
    Am J Clin Nutr 80:1570-3. 2004
    ..Zinc supplements are used extensively in medicine and research and for public health purposes in the prevention and treatment of zinc deficiency. However, little is known about the efficiency of zinc utilization after different doses...
  20. ncbi request reprint Complementary feeding: clinically relevant factors affecting timing and composition
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80252, USA
    Am J Clin Nutr 85:639S-645S. 2007
    ....
  21. ncbi request reprint Measurements of zinc absorption: application and interpretation in research designed to improve human zinc nutriture
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Box C225, 4200 E 9th Av, Denver, Colorado, 80262, USA
    Int J Vitam Nutr Res 75:385-93. 2005
    ..They also suggest the potential utility of measurements of the quantity of zinc absorbed when evaluating the zinc status of populations...
  22. ncbi request reprint Meat as a first complementary food for breastfed infants: feasibility and impact on zinc intake and status
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Pediatr Gastroenterol Nutr 42:207-14. 2006
    ..This study was undertaken to assess the feasibility and effects of consuming either meat or iron-fortified infant cereal as the first complementary food...
  23. pmc Absorption of calcium from tortilla meals prepared from low-phytate maize
    K Michael Hambidge
    Department of Pediatrics, Section of Nutrition, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Clin Nutr 82:84-7. 2005
    ..Bioavailability of calcium is, however, compromised by phytate, which is present in large quantities in maize kernels and is only modestly reduced by nixtamalization...
  24. ncbi request reprint Changes in zinc absorption during development
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Pediatr 149:S64-8. 2006
    ..Normal homeostatic mechanisms in the premature infant prevented efficient absorption of the quantity of Zn required or/and optimal conservation of endogenous Zn...
  25. ncbi request reprint Community-based dietary phytate reduction and its effect on iron status in Malawian children
    Mark J Manary
    Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
    Ann Trop Paediatr 22:133-6. 2002
    ..Phytate was removed by soaking maize flour in excess water with phytase and decanting the water before cooking the flour. Iron status, as measured by soluble transferrin receptor and zinc protoporphyrin, was improved but not normal...
  26. pmc A mathematical model of zinc absorption in humans as a function of dietary zinc and phytate
    Leland V Miller
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Nutr 137:135-41. 2007
    ..The model was judged to be valid and of immediate value for studying and predicting absorption. A version of the model incorporating a passive absorption mechanism was not supported by the available data...
  27. ncbi request reprint Zinc, low birth weight, and breastfeeding
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Pediatrics 112:1419-20. 2003
  28. ncbi request reprint Zinc deficiency: a special challenge
    K Michael Hambidge
    Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80220, USA
    J Nutr 137:1101-5. 2007
    ..Barriers to acceptability and availability of affordable meat are considered, but these are neither universal nor irresolvable in all populations...
  29. ncbi request reprint Exchangeable zinc pool size at birth is smaller in small-for-gestational-age than in appropriate-for-gestational-age preterm infants
    Nancy F Krebs
    Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Am J Clin Nutr 84:1340-3. 2006
    ..Small-for-gestational-age (SGA) infants are susceptible to postnatal zinc deficiency, but whether this susceptibility is due to intrauterine factors or to high postnatal growth requirements is unknown...