Research Topics
| K HambidgeSummaryAffiliation: University of Colorado Denver Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Fecal calprotectin levels are higher in rural than in urban Chinese infants and negatively associated with growthJin rong Liu
Department of Child and Adolescent Health Care, MOE Shanghai Key Laboratory of Children s Environmental Health, Xinhua Hospital, ShanghaiJiao Tong University, School of Medicine, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, 1665 Kongjiang Road, Shanghai 200092, China
BMC Pediatr 12:129. 2012..To examine a possible relationship between linear growth and gut inflammation, we compared fecal calprotectin levels in 6 month old infants from poor rural vs affluent urban families...- Infant stunting is associated with short maternal statureK Michael Hambidge
Department of Pediatrics, Section of Nutrition, University of Colorado, Aurora, CO 80045, USA
J Pediatr Gastroenterol Nutr 54:117-9. 2012..Maternal height is independently associated with infant LAZ and stunting (LAZ <-2) at both 6 and 12 months (P < 0.001) and with linear growth velocity from 6 to 12 months (P = 0.0023)... - Communities, birth attendants and health facilities: a continuum of emergency maternal and newborn care (the Global Network's EmONC trial)Omrana Pasha
Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan
BMC Pregnancy Childbirth 10:82. 2010..However, the effectiveness of emergency obstetric and neonatal care services has never been proven. Also unproven is the effectiveness of community mobilization and community birth attendant training to improve pregnancy outcomes... - Complementary feeding: a Global Network cluster randomized controlled trialNancy F Krebs
University of Colorado Denver, Aurora, CO, USA
BMC Pediatr 11:4. 2011..Animal source foods in particular are cited as essential to achieve micronutrient requirements. The efficacy of the recommendation for regular meat consumption, however, has not been systematically evaluated... 
Physiological requirements for zincK Michael Hambidge
Pediatric Nutrition, University of Colorado Denver, Aurora, CO, USA
Int J Vitam Nutr Res 81:72-8. 2011..The lessons to be learned from this review are discussed together with suggestions for future action by IOM as well as a constructive role for IZiNCG...- Evaluation of meat as a first complementary food for breastfed infants: impact on iron intakeK Michael Hambidge
The University of Colorado Denver, Aurora, Colorado 80045, USA
Nutr Rev 69:S57-63. 2011..These trials are presently in progress in poor communities in Guatemala, Pakistan, Zambia, Democratic Republic of the Congo, and China... - Micronutrient bioavailability: Dietary Reference Intakes and a future perspectiveK Michael Hambidge
Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Aurora, CO 80045, USA
Am J Clin Nutr 91:1430S-1432S. 2010..These factors, it is argued, are best considered separately from even a broad definition of bioavailability and have the potential to provide new insights into some micronutrient requirements... - Zinc bioavailability and homeostasisK Michael Hambidge
Department of Pediatrics, Section of Nutrition, University of Colorado Denver, Denver, CO, USA
Am J Clin Nutr 91:1478S-1483S. 2010..The effects of phytate on intestinal losses of endogenous zinc merit further investigation but are probably not of the same magnitude as its inhibitory effects on absorption of exogenous zinc... 
Intestinal excretion of endogenous zinc in Guatemalan school childrenK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
J Nutr 137:1747-9. 2007..Supported by other recent childhood data, these results suggest that the current estimates of EFZ(PR) used in the calculation of Zn requirements for children are misleadingly low...- Zinc homeostasis in Malawian children consuming a high-phytate, maize-based dietMark J Manary
Department of Pediatrics, Washington University School of Medicine, St Louis, USA
Am J Clin Nutr 75:1057-61. 2002..The gastrointestinal tract plays a central role in absorbing and conserving zinc, yet it has not been carefully studied in such children... - Zinc absorption during late pregnancy in rural southern EthiopiaK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO, USA
Am J Clin Nutr 84:1102-6. 2006..Little is yet known about zinc absorption in late pregnancy, and no information on absorption from the total diet is available... - The use of dysprosium to measure endogenous zinc excretion in feces eliminates the necessity of complete fecal collectionsLeland V Miller
University of Colorado Denver, Department of Pediatrics, Aurora, CO 80045, USA
J Nutr 140:1524-8. 2010..We found that the measurement of the sample Dy:Zn ratio was useful for selecting samples for measurement. We conclude that the Dy method of determining EFZ is a valid and less burdensome alternative to current techniques... - Dysprosium as a nonabsorbable fecal marker in studies of zinc homeostasisXiao-Yang Sheng
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Am J Clin Nutr 82:1017-23. 2005..95) with those from the fecal monitoring and dual-isotope-tracer ratio methods. CONCLUSION: Administration of dysprosium is a useful means of determining the completeness of fecal collections and of measuring zinc absorption... - Dietary reference intakes for zinc may require adjustment for phytate intake based upon model predictionsK Michael Hambidge
Department of Pediatrics, Section of Nutrition, University of Colorado, School of Medicine, Denver, CO 80262, USA
J Nutr 138:2363-6. 2008..4 mg Zn/d. Extrapolation of the model suggested, for example, that with 900 mg/d phytate, 100 mg dietary Zn is required to attain 6.4 mg absorbed Zn/d. Experimental studies with higher Zn intakes are required to test these predictions... - Zinc absorption from low-phytate hybrids of maize and their wild-type isohybridsK Michael Hambidge
University of Colorado Health Sciences Center, Department of Pediatrics, Section of Nutrition, Denver 80262, USA
Am J Clin Nutr 79:1053-9. 2004.... - Exchangeable zinc pool size in infants is related to key variables of zinc homeostasisNancy F Krebs
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
J Nutr 133:1498S-501S. 2003..We conclude that the amount of absorbed zinc is not tightly regulated, and that endogenous fecal zinc is dependent on and responsive to the zinc status of the organism... - Complementary feeding: clinically relevant factors affecting timing and compositionNancy F Krebs
Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80252, USA
Am J Clin Nutr 85:639S-645S. 2007.... - Measurements of zinc absorption: application and interpretation in research designed to improve human zinc nutritureK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Box C225, 4200 E 9th Av, Denver, Colorado, 80262, USA
Int J Vitam Nutr Res 75:385-93. 2005..They also suggest the potential utility of measurements of the quantity of zinc absorbed when evaluating the zinc status of populations... - Zinc absorption as a function of the dose of zinc sulfate in aqueous solutionCuong D Tran
Section of Nutrition, Department of Pediatrics, The University of Colorado Health Science Center, Denver, USA
Am J Clin Nutr 80:1570-3. 2004..Zinc supplements are used extensively in medicine and research and for public health purposes in the prevention and treatment of zinc deficiency. However, little is known about the efficiency of zinc utilization after different doses... - Community-based dietary phytate reduction and its effect on iron status in Malawian childrenMark J Manary
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
Ann Trop Paediatr 22:133-6. 2002..Phytate was removed by soaking maize flour in excess water with phytase and decanting the water before cooking the flour. Iron status, as measured by soluble transferrin receptor and zinc protoporphyrin, was improved but not normal... - Changes in zinc absorption during developmentK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
J Pediatr 149:S64-8. 2006..Normal homeostatic mechanisms in the premature infant prevented efficient absorption of the quantity of Zn required or/and optimal conservation of endogenous Zn... - Absorption of calcium from tortilla meals prepared from low-phytate maizeK Michael Hambidge
Department of Pediatrics, Section of Nutrition, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Am J Clin Nutr 82:84-7. 2005..Bioavailability of calcium is, however, compromised by phytate, which is present in large quantities in maize kernels and is only modestly reduced by nixtamalization... - Meat as a first complementary food for breastfed infants: feasibility and impact on zinc intake and statusNancy F Krebs
Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
J Pediatr Gastroenterol Nutr 42:207-14. 2006..This study was undertaken to assess the feasibility and effects of consuming either meat or iron-fortified infant cereal as the first complementary food... - A mathematical model of zinc absorption in humans as a function of dietary zinc and phytateLeland V Miller
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
J Nutr 137:135-41. 2007..The model was judged to be valid and of immediate value for studying and predicting absorption. A version of the model incorporating a passive absorption mechanism was not supported by the available data... - Zinc, low birth weight, and breastfeedingK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Pediatrics 112:1419-20. 2003 - Zinc deficiency: a special challengeK Michael Hambidge
Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80220, USA
J Nutr 137:1101-5. 2007..Barriers to acceptability and availability of affordable meat are considered, but these are neither universal nor irresolvable in all populations... - Exchangeable zinc pool size at birth is smaller in small-for-gestational-age than in appropriate-for-gestational-age preterm infantsNancy F Krebs
Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
Am J Clin Nutr 84:1340-3. 2006..Small-for-gestational-age (SGA) infants are susceptible to postnatal zinc deficiency, but whether this susceptibility is due to intrauterine factors or to high postnatal growth requirements is unknown...
Research Grants
- Zn & Maternal-Infant Brain Function in S. Ethiopia: Randomized Controlled TrialsK Hambidge; Fiscal Year: 2009....