Marc W Halterman

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity
    M W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Gene Med 8:1320-8. 2006
  2. ncbi In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures
    Marc W Halterman
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States
    J Neurosci Methods 177:348-54. 2009
  3. ncbi Teaching NeuroImage: tremor in aqueductal stenosis and response to endoscopic third ventriculostomy
    Marc W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurology 68:E29-31. 2007
  4. ncbi Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
    Marc W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Mol Cell Neurosci 38:125-37. 2008
  5. ncbi An improved method for the study of apoptosis-related genes using the tet-on system
    Marc W Halterman
    Department of Neurology, Center for Neural Development and Disease, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biomol Screen 16:332-7. 2011
  6. ncbi The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death
    Marc W Halterman
    Department of Neurology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Biol Chem 285:21329-40. 2010
  7. ncbi Reporter gene transfer induces apoptosis in primary cortical neurons
    Eric R Detrait
    Center for Aging and Developmental Biology, Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York 14642, USA
    Mol Ther 5:723-30. 2002
  8. ncbi The paradox of the neutrophil's role in tissue injury
    George B Segel
    Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
    J Leukoc Biol 89:359-72. 2011
  9. ncbi Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress
    Alliya Qazi
    Department of Pediatrics, Golisano Children s Hospital at URMC, University of Rochester Medical Center, Rochester, NY 14642, USA
    Oxid Med Cell Longev 2011:391659. 2011
  10. ncbi Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers
    W J Bowers
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Gene Ther 8:111-20. 2001

Collaborators

Detail Information

Publications10

  1. ncbi Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity
    M W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Gene Med 8:1320-8. 2006
    ..These findings offer a novel approach to improving the titer and toxicity profiles of HSV-based viral vectors...
  2. ncbi In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures
    Marc W Halterman
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States
    J Neurosci Methods 177:348-54. 2009
    ..It is anticipated that this in vitro protocol will facilitate the identification of novel genes involved in both developmental and disease-relevant signaling pathways...
  3. ncbi Teaching NeuroImage: tremor in aqueductal stenosis and response to endoscopic third ventriculostomy
    Marc W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurology 68:E29-31. 2007
  4. ncbi Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
    Marc W Halterman
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Mol Cell Neurosci 38:125-37. 2008
    ..These data indicate that the pathologic response in cortical neurons induced by hypoxia involves both the loss of c/EBP-beta-mediated survival signals and activation of pro-death pathways originating from the endoplasmic reticulum...
  5. ncbi An improved method for the study of apoptosis-related genes using the tet-on system
    Marc W Halterman
    Department of Neurology, Center for Neural Development and Disease, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biomol Screen 16:332-7. 2011
    ..It is anticipated that these protocol modifications will improve the performance of tet-regulated genetic screens, particularly in situations where cell death is used as a primary end point...
  6. ncbi The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death
    Marc W Halterman
    Department of Neurology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Biol Chem 285:21329-40. 2010
    ..Collectively, these findings indicate CHOP serves a more complex role in the neuronal response to hypoxic stress with involvement in both ischemic preconditioning and delayed neuroprotection...
  7. ncbi Reporter gene transfer induces apoptosis in primary cortical neurons
    Eric R Detrait
    Center for Aging and Developmental Biology, Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York 14642, USA
    Mol Ther 5:723-30. 2002
    ..This work underscores the need for careful design of gene expression constructs. Moreover, in studies where cell injury or toxicity is being evaluated, their use should be carefully considered...
  8. ncbi The paradox of the neutrophil's role in tissue injury
    George B Segel
    Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
    J Leukoc Biol 89:359-72. 2011
    ..In this review, we summarize the evidence for its role as a mediator of tissue injury in these seven conditions, making it or its products potential therapeutic targets...
  9. ncbi Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress
    Alliya Qazi
    Department of Pediatrics, Golisano Children s Hospital at URMC, University of Rochester Medical Center, Rochester, NY 14642, USA
    Oxid Med Cell Longev 2011:391659. 2011
    ..We therefore examined the effects of deletion of Chopper on the effects of p75ICD on in vitro cell culture systems in which p75ICD is pro- or antiapoptotic, respectively...
  10. ncbi Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers
    W J Bowers
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Gene Ther 8:111-20. 2001
    ..Increased helper virus-free amplicon titers resulting from these modifications will make in vivo transduction experiments more feasible...