SCOTT DAVID HALPERN

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Re-examining ethical obligations in the intensive care unit: HIV disclosure to surrogates
    Anthony T Vernillo
    New York University College of Dentistry, Department of Oral and Maxillofacial Pathology, Radiology and Medicine, New York, New York 10010, USA
    Crit Care 11:125. 2007
  2. ncbi request reprint Nonconsented human immunodeficiency virus testing among critically ill patients: intensivists' practices and the influence of state laws
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, 423 Guardian Dr, 711 Blockley Hall, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 167:2323-8. 2007
  3. pmc Regulated payments for living kidney donation: an empirical assessment of the ethical concerns
    Scott D Halpern
    University of Pennsylvania School of Medicine and Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104 6021, USA
    Ann Intern Med 152:358-65. 2010
  4. pmc No child left behind: Enrolling children and adults simultaneously in critical care randomized trials
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine SDH, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Crit Care Med 37:2638-41. 2009
  5. doi request reprint The ethics of randomized clinical trials in pulmonary arterial hypertension
    Scott D Halpern
    Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Proc Am Thorac Soc 5:631-5. 2008
  6. doi request reprint Misclassification of pulmonary hypertension due to reliance on pulmonary capillary wedge pressure rather than left ventricular end-diastolic pressure
    Scott D Halpern
    Division of Pulmonary, Allergy and Critical CareMedicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Chest 136:37-43. 2009
  7. ncbi request reprint Terminal withdrawal of life-sustaining supplemental oxygen
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 296:1397-400. 2006
  8. ncbi request reprint Development of an e-mail database of US intensive care physicians
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Crit Care 22:28-31. 2007
  9. ncbi request reprint Harnessing the power of default options to improve health care
    Scott D Halpern
    Department of Medicine, The Leonard Davis Institute of Health Economics, the Center for Bioethics, University of Pennsylvania, Philadelphia 19104 6021, USA
    N Engl J Med 357:1340-4. 2007
  10. ncbi request reprint Preevent vaccination against smallpox: a survey of pediatric emergency health care providers
    Worth W Everett
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Centers for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 23:332-7. 2004

Detail Information

Publications39

  1. pmc Re-examining ethical obligations in the intensive care unit: HIV disclosure to surrogates
    Anthony T Vernillo
    New York University College of Dentistry, Department of Oral and Maxillofacial Pathology, Radiology and Medicine, New York, New York 10010, USA
    Crit Care 11:125. 2007
    ..We also provide a tabulation of individual US state laws relevant to disclosure of HIV status...
  2. ncbi request reprint Nonconsented human immunodeficiency virus testing among critically ill patients: intensivists' practices and the influence of state laws
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, 423 Guardian Dr, 711 Blockley Hall, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 167:2323-8. 2007
    ..Human immunodeficiency virus (HIV) testing can improve care for many critically ill patients, but state laws and institutional policies may impede such testing when patients cannot provide consent...
  3. pmc Regulated payments for living kidney donation: an empirical assessment of the ethical concerns
    Scott D Halpern
    University of Pennsylvania School of Medicine and Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104 6021, USA
    Ann Intern Med 152:358-65. 2010
    ..Although regulated payments to encourage living kidney donation could reduce morbidity and mortality among patients waiting for a kidney transplant, doing so raises several ethical concerns...
  4. pmc No child left behind: Enrolling children and adults simultaneously in critical care randomized trials
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine SDH, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Crit Care Med 37:2638-41. 2009
    ..We sought to evaluate the ethical, methodologic, and practical arguments for and against studying critical care interventions in adults and children simultaneously rather than sequentially...
  5. doi request reprint The ethics of randomized clinical trials in pulmonary arterial hypertension
    Scott D Halpern
    Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Proc Am Thorac Soc 5:631-5. 2008
    ....
  6. doi request reprint Misclassification of pulmonary hypertension due to reliance on pulmonary capillary wedge pressure rather than left ventricular end-diastolic pressure
    Scott D Halpern
    Division of Pulmonary, Allergy and Critical CareMedicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Chest 136:37-43. 2009
    ..We sought to determine the calibration, discrimination, and diagnostic accuracy of PCWP, using simultaneously measured left ventricular end-diastolic pressure (LVEDP) as the "gold standard."..
  7. ncbi request reprint Terminal withdrawal of life-sustaining supplemental oxygen
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 296:1397-400. 2006
  8. ncbi request reprint Development of an e-mail database of US intensive care physicians
    Scott D Halpern
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Crit Care 22:28-31. 2007
    ..We sought to develop an e-mail database for all intensivists associated with US training programs in critical care medicine (academic intensivists) and to determine the feasibility of using this database to survey intensivists...
  9. ncbi request reprint Harnessing the power of default options to improve health care
    Scott D Halpern
    Department of Medicine, The Leonard Davis Institute of Health Economics, the Center for Bioethics, University of Pennsylvania, Philadelphia 19104 6021, USA
    N Engl J Med 357:1340-4. 2007
  10. ncbi request reprint Preevent vaccination against smallpox: a survey of pediatric emergency health care providers
    Worth W Everett
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Centers for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 23:332-7. 2004
    ..In January 2003, smallpox vaccinations were offered to health care workers to create hospital-based teams prepared to care for patients with smallpox as part of national bioterrorism preparedness activities...
  11. doi request reprint Informing candidates for solid-organ transplantation about donor risk factors
    Scott D Halpern
    Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, USA
    N Engl J Med 358:2832-7. 2008
  12. ncbi request reprint Determinants of transplant surgeons' willingness to provide organs to patients infected with HBV, HCV or HIV
    Scott D Halpern
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, 19104 6021, USA
    Am J Transplant 5:1319-25. 2005
    ..HIV-infected patients should have equal access to organs unless or until evidence emerges that they fare substantially worse than other potential recipients...
  13. ncbi request reprint HIV testing without consent in critically ill patients
    Scott D Halpern
    Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 294:734-7. 2005
  14. pmc Towards evidence based bioethics
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine 115 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    BMJ 331:901-3. 2005
  15. ncbi request reprint Incentive models to increase living kidney donation: encouraging without coercing
    Ajay K Israni
    Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Am J Transplant 5:15-20. 2005
    ..We recommend the use of the expense reimbursement model along with these safeguards, in order to increase rates of living kidney donation...
  16. ncbi request reprint Utility of the systemic inflammatory response syndrome (SIRS) criteria in predicting the onset of septic shock in hospitalized patients with hematologic malignancies
    Anthony Mato
    Hematology and Oncology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Cancer Biol Ther 8:1095-1100. 2009
    ..The systemic inflammatory response syndrome (SIRS) criteria have not been validated in patients with hematologic malignancies (HM)...
  17. ncbi request reprint Prospective preference assessment: a method to enhance the ethics and efficiency of randomized controlled trials
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, Center for Bioethics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Control Clin Trials 23:274-88. 2002
    ..It is concluded that PPA is a feasible approach to a more democratic and efficient research process and that its adoption would be consistent with current trends in health care...
  18. ncbi request reprint The continuing unethical conduct of underpowered clinical trials
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 108 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    JAMA 288:358-62. 2002
    ..In both cases, investigators must inform prospective subjects that their participation may only indirectly contribute to future health care benefits...
  19. pmc Physicians' preferences for active-controlled versus placebo-controlled trials of new antihypertensive drugs
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Gen Intern Med 17:689-95. 2002
    ..To evaluate physicians' preferences for referring patients to, and using information from, active-controlled trials (ACTs) versus placebo-controlled trials (PCTs) of new antihypertensive drugs...
  20. pmc Determinants of the decision to accept a kidney from a donor at increased risk for blood-borne viral infection
    PETER P REESE
    University of Pennsylvania, Renal Division, Department of Medicine, Philadelphia, PA, USA
    Clin J Am Soc Nephrol 5:917-23. 2010
    ..This study aimed to identify the proportion of kidney transplant candidates that would accept a kidney from a DIRVI and the factors that influenced this decision...
  21. ncbi request reprint Evaluating preference effects in partially unblinded, randomized clinical trials
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 108 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Clin Epidemiol 56:109-15. 2003
    ..It is concluded that investigators could use these methods to quantify potential preference effects in partially unblinded RCTs, and thereby more accurately estimate the specific effects of treatments...
  22. ncbi request reprint Smallpox vaccination: a national survey of emergency health care providers
    Worth W Everett
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Acad Emerg Med 10:606-11. 2003
    ..Although emergency health care providers are among the first targeted for vaccination, little is known about how these providers view the risks and benefits of SP vaccination...
  23. ncbi request reprint Hypertensive patients' willingness to participate in placebo-controlled trials: implications for recruitment efficiency
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Am Heart J 146:985-92. 2003
    ....
  24. ncbi request reprint Willingness of dialysis patients to participate in a randomized controlled trial of daily dialysis
    Ajay K Israni
    Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Kidney Int 65:990-8. 2004
    ..However, there is concern that difficulties recruiting patients may prevent the successful completion of such trials if patients believe the inconveniences of daily dialysis outweigh any potential health benefits...
  25. ncbi request reprint Empirical assessment of whether moderate payments are undue or unjust inducements for participation in clinical trials
    Scott D Halpern
    Department of Medicine, Centers for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Arch Intern Med 164:801-3. 2004
    ..Paying patients to participate in clinical trials is ethically controversial. However, there has been no empirical documentation regarding whether payment represents an undue or unjust inducement...
  26. ncbi request reprint Decisions devoid of data?
    Scott D Halpern
    School of Medicine, University of Pennsylvania, USA
    Am J Bioeth 6:55-6; discussion W51-3. 2006
  27. ncbi request reprint Commentary: Improving response rates to mailed surveys: what do we learn from randomized controlled trials?
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Int J Epidemiol 32:637-8. 2003
  28. ncbi request reprint Randomized trial of 5 dollars versus 10 dollars monetary incentives, envelope size, and candy to increase physician response rates to mailed questionnaires
    Scott D Halpern
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Med Care 40:834-9. 2002
    ..However, the effectiveness and cost-effectiveness of several strategies to increase response rates are uncertain...
  29. ncbi request reprint Solid-organ transplantation in HIV-infected patients
    Scott D Halpern
    University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    N Engl J Med 347:284-7. 2002
  30. ncbi request reprint Willingness of patients to switch from conventional to daily hemodialysis: looking before we leap
    Scott D Halpern
    Department of Medicine, University of Pennsylvania, Philadelphia, USA
    Am J Med 116:606-12. 2004
    ....
  31. pmc Inadequate hepatitis B vaccination and post-exposure evaluation among transplant surgeons: prevalence, correlates, and implications
    Scott D Halpern
    Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Ann Surg 244:305-9. 2006
    ....
  32. doi request reprint The future of the orthopaedic clinician-scientist: part II: Identification of factors that may influence orthopaedic residents' intent to perform research
    Jaimo Ahn
    Department of Orthopaedic Surgery, 3400 Spruce Street, 2 Silverstein, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 92:1041-6. 2010
    ..Therefore, we sought to assess resident opinions regarding plans and incentives for future research and the opinions of academic chairs who must support them...
  33. ncbi request reprint Epidemiologic studies of adverse effects of anti-retroviral drugs: how well is statistical power reported
    Scott D Halpern
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 14:155-61. 2005
    ..To determine whether there is a difference in average statistical power between pharmacoepidemiologic studies of anti-retroviral adverse drug effects (ADEs) sponsored by for-profit versus non-profit organizations...
  34. ncbi request reprint Evidence-based equipoise and research responsiveness
    Scott D Halpern
    Am J Bioeth 6:1-4. 2006
  35. doi request reprint Research recruitment via camouflaged sampling: addressing the legal and ethical aspects of privacy concerns
    Hilary M Wandall
    Merck and Co, Inc, NJ, USA
    Pharmacoepidemiol Drug Saf 17:798-800. 2008
  36. ncbi request reprint Post-call accidents
    Scott D Halpern
    N Engl J Med 352:1491-2; author reply 1491-2. 2005
  37. ncbi request reprint Response to Willingness to participate and enroll in a phase 3 preventive HIV-1 vaccine trial
    Scott D Halpern
    J Acquir Immune Defic Syndr 33:412. 2003
  38. ncbi request reprint Reporting enrollment in clinical trials
    Scott D Halpern
    Ann Intern Med 137:1007-8; author reply 1007-8. 2002
  39. ncbi request reprint Re: "Ethics and sample size"
    Scott D Halpern
    Am J Epidemiol 162:195-6; author reply 196. 2005

Research Grants1

  1. Comparative Efficacy, Acceptance and Effectiveness of Health Incentive Structures
    SCOTT DAVID HALPERN; Fiscal Year: 2010
    ..This work will both clarify mechanisms by which incentives alter behaviors, and will identify better ways to reduce smoking and other important causes of preventable death. ..