Alfred P Hallstrom

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Characteristics of heart beat intervals and prediction of death
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Clinical Trial Center, 1107 N E 45th Street, Suite 505, Seattle, WA 98105 4689, United States
    Int J Cardiol 100:37-45. 2005
  2. doi request reprint Clinical criteria for predicting benefit of ICD/PM in post myocardial infarction patients: an AVID and CAST analysis
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105, USA
    J Interv Card Electrophysiol 23:159-66. 2008
  3. ncbi request reprint Dispatcher assisted CPR: implementation and potential benefit. A 12-year study
    Alfred P Hallstrom
    Department of Biostatistics, Clinical Trial Center, University of Washington, 1107 N E 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 57:123-9. 2003
  4. ncbi request reprint Do arrhythmia patients improve survival by participating in randomized clinical trials? Observations from the Cardiac Arrhythmia Suppression Trial (CAST)and the Antiarrhythmics Versus Implantable Defibrillators Trial (AVID)
    Al Hallstrom
    Clinical Trial Center, University of Washington, 1107 NE 45th Street, Suite 405, Seattle, WA 98105 4689, USA
    Control Clin Trials 24:341-52. 2003
  5. ncbi request reprint The relationship between shocks and survival in out-of-hospital cardiac arrest patients initially found in PEA or asystole
    Al Hallstrom
    Department of Biostatistics, University of Washington, 1107 NE 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 74:418-26. 2007
  6. ncbi request reprint What is the appropriate outcome for studies of treatments for out-of-hospital cardiac arrest?
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, 1107 NE 45th Street, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 71:194-203. 2006
  7. ncbi request reprint Manual chest compression vs use of an automated chest compression device during resuscitation following out-of-hospital cardiac arrest: a randomized trial
    Al Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105, USA
    JAMA 295:2620-8. 2006
  8. ncbi request reprint Structural relationships between measures based on heart beat intervals: potential for improved risk assessment
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105 4689, USA
    IEEE Trans Biomed Eng 51:1414-20. 2004
  9. ncbi request reprint Pre-randomization and de-randomization in emergency medical research: new names and rigorous criteria for old methods
    Alfred P Hallstrom
    Department of Biostatistics, Clinical Trial Center, University of Washington, 1107 N E 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 65:65-9. 2005
  10. doi request reprint Treatment of asystole and PEA
    A Hallstrom
    University of Washington, Seattle, WA 98105, United States
    Resuscitation 80:975-6. 2009

Detail Information

Publications35

  1. ncbi request reprint Characteristics of heart beat intervals and prediction of death
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Clinical Trial Center, 1107 N E 45th Street, Suite 505, Seattle, WA 98105 4689, United States
    Int J Cardiol 100:37-45. 2005
    ....
  2. doi request reprint Clinical criteria for predicting benefit of ICD/PM in post myocardial infarction patients: an AVID and CAST analysis
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105, USA
    J Interv Card Electrophysiol 23:159-66. 2008
    ....
  3. ncbi request reprint Dispatcher assisted CPR: implementation and potential benefit. A 12-year study
    Alfred P Hallstrom
    Department of Biostatistics, Clinical Trial Center, University of Washington, 1107 N E 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 57:123-9. 2003
    ....
  4. ncbi request reprint Do arrhythmia patients improve survival by participating in randomized clinical trials? Observations from the Cardiac Arrhythmia Suppression Trial (CAST)and the Antiarrhythmics Versus Implantable Defibrillators Trial (AVID)
    Al Hallstrom
    Clinical Trial Center, University of Washington, 1107 NE 45th Street, Suite 405, Seattle, WA 98105 4689, USA
    Control Clin Trials 24:341-52. 2003
    ..Overall these observational analyses suggest a net improvement in survival for the participants in these two trials...
  5. ncbi request reprint The relationship between shocks and survival in out-of-hospital cardiac arrest patients initially found in PEA or asystole
    Al Hallstrom
    Department of Biostatistics, University of Washington, 1107 NE 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 74:418-26. 2007
    ....
  6. ncbi request reprint What is the appropriate outcome for studies of treatments for out-of-hospital cardiac arrest?
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, 1107 NE 45th Street, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 71:194-203. 2006
    ..Both admittance and survival are important outcomes and need to be considered jointly, that is, as a bivariate outcome...
  7. ncbi request reprint Manual chest compression vs use of an automated chest compression device during resuscitation following out-of-hospital cardiac arrest: a randomized trial
    Al Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105, USA
    JAMA 295:2620-8. 2006
    ..Compared with manual chest compression, an automated load-distributing band (LDB) chest compression device produces greater blood flow to vital organs and may improve resuscitation outcomes...
  8. ncbi request reprint Structural relationships between measures based on heart beat intervals: potential for improved risk assessment
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105 4689, USA
    IEEE Trans Biomed Eng 51:1414-20. 2004
    ..In conclusion, we found that adjusting for HR and the number of VPCs in heart-beat related ambulatory ECG measures has the potential to significantly improve the power of these measures to risk stratify cardiac patients...
  9. ncbi request reprint Pre-randomization and de-randomization in emergency medical research: new names and rigorous criteria for old methods
    Alfred P Hallstrom
    Department of Biostatistics, Clinical Trial Center, University of Washington, 1107 N E 45th St, Suite 505, Seattle, WA 98105 4689, USA
    Resuscitation 65:65-9. 2005
    ..It is possible to use these techniques to successfully complete clinical trials that would not have been possible using only standard methodology and still ensure that results are without bias...
  10. doi request reprint Treatment of asystole and PEA
    A Hallstrom
    University of Washington, Seattle, WA 98105, United States
    Resuscitation 80:975-6. 2009
    ..However, the "yield" of survivors comes largely from the non-shocked patients. Therefore, it is critical that we start evaluating treatments specifically for the PEA and asystole groups...
  11. ncbi request reprint Should time from cardiac arrest until call to emergency medical services (EMS) be collected in EMS research?
    Alfred P Hallstrom
    Department of Biostatistics, University of Washington, Seattle, WA 98105, USA
    Crit Care Med 30:S127-30. 2002
    ..The most likely bias would tend to cause an overestimate of the slope. It is suggested that unless the time from collapse to placing the 911 call can be obtained accurately and without bias, it is probably not worthwhile to do so...
  12. doi request reprint A modified Wilcoxon test for non-negative distributions with a clump of zeros
    Alfred P Hallstrom
    Department of Biostatistics, Seattle, WA 98105, U S A
    Stat Med 29:391-400. 2010
    ....
  13. ncbi request reprint Relationship between rehospitalization and future death in patients treated for potentially lethal arrhythmia
    A P Hallstrom
    University of Washington, Seattle, USA
    J Cardiovasc Electrophysiol 12:990-5. 2001
    ..The aim of this study was to evaluate whether rehospitalization following implementation of an intervention is a reasonable surrogate for death...
  14. ncbi request reprint Advantages and disadvantages of trial designs: a review of analysis methods for ICD studies. AVID Investigators
    A P Hallstrom
    Department of Biostatistics, University of Washington, Seattle 98105, USA
    Pacing Clin Electrophysiol 23:1029-38. 2000
    ..Particular issues related to the use of the ICD for example, mode of death, inability to blind, selection practice, and treatment decision times make this a natural pedagogic platform...
  15. ncbi request reprint Lower observed versus expected (based on U.S. age and gender specific rates) survival in patients treated for near-fatal ventricular arrhythmias
    Shalini L Kulasingam
    AVID Clinical Trial Center and University of Washington, Seattle, Washington, USA
    Pacing Clin Electrophysiol 27:230-4. 2004
    ....
  16. ncbi request reprint Patients at lower risk of arrhythmia recurrence: a subgroup in whom implantable defibrillators may not offer benefit. Antiarrhythmics Versus Implantable Defibrillator (AVID) Trial Investigators
    A P Hallstrom
    University of Washington, Seattle 98105, USA
    J Am Coll Cardiol 37:1093-9. 2001
    ..The goal of this study was to identify subgroups of arrhythmia patients who do not benefit from use of the implantable cardiac defibrillator (ICD)...
  17. ncbi request reprint Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out-of-hospital ventricular fibrillation
    L A Cobb
    Department of Medicine, University of Washington, Harborview Medical Center, Seattle 98104, USA
    JAMA 281:1182-8. 1999
    ..Studies in animals have shown improved outcomes when cardiopulmonary resuscitation (CPR) was administered prior to an initial shock for VF of several minutes' duration...
  18. doi request reprint Heart rate, pacing, and outcome in the Dual Chamber and VVI Implantable Defibrillator (DAVID) trials
    Peter J Kudenchuk
    University of Washington, Seattle, Washginton 98195 6422, USA
    Heart Rhythm 6:1129-35. 2009
    ....
  19. ncbi request reprint Public-access defibrillation and survival after out-of-hospital cardiac arrest
    A P Hallstrom
    University of Washington, Seattle, USA
    N Engl J Med 351:637-46. 2004
    ..The rate of survival after out-of-hospital cardiac arrest is low. It is not known whether this rate will increase if laypersons are trained to attempt defibrillation with the use of automated external defibrillators (AEDs)...
  20. pmc Two simple questions to assess neurologic outcomes at 3 months after out-of-hospital cardiac arrest: experience from the public access defibrillation trial
    W T Longstreth
    Department of Neurology, School of Medicine, University of Washington, Seattle, WA, USA
    Resuscitation 81:530-3. 2010
    ..Two simple questions have been used to classify neurologic outcome in patients with stroke. Could they be similarly applied to patients with cardiac arrest?..
  21. ncbi request reprint Time to arrhythmic, ischemic, and heart failure events: exploratory analyses to elucidate mechanisms of adverse drug effects in the Cardiac Arrhythmia Suppression Trial
    A P Hallstrom
    Clinical Trial Center, University of Washington, Seattle 98105, USA
    Am Heart J 130:71-9. 1995
    ..We were unable to identify any specific mechanism to explain the adverse effect of encainide and flecainide...
  22. ncbi request reprint Congestive heart failure after acute myocardial infarction in patients receiving antiarrhythmic agents for ventricular premature complexes (Cardiac Arrhythmia Pilot Study)
    H L Greene
    CAPS Coordinating Center, University of Washington, Seattle 98105
    Am J Cardiol 63:393-8. 1989
    ..Although patients with severely impaired ejection fraction were excluded, new or worsened CHF was common in follow-up during CAPS...
  23. ncbi request reprint The healthy responder phenomenon in non-randomized clinical trials. CAST Investigators
    A P Hallstrom
    CAST Coordinating Center, Department of Biostatistics, University of Washington, Seattle 98105
    Stat Med 10:1621-31. 1991
    ..We conclude that, in demonstration of a drug effect, randomized trials are essential...
  24. ncbi request reprint A comparison of the AVID and DAVID trials of implantable defibrillators
    Arjun Sharma
    Mercy Hospital, Sacramento, California 95819, USA
    Am J Cardiol 95:1431-5. 2005
    ..If DDDR ICDs had been used in the AVID trial, benefit from ICDs for patients with serious ventricular arrhythmias could have been missed...
  25. ncbi request reprint Implantable cardioverter defibrillator utilization based on discharge diagnoses from Medicare and managed care patients
    Jeremy N Ruskin
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Cardiovasc Electrophysiol 13:38-43. 2002
    ..To assess the current utilization of this therapy, we estimated the number of patients at risk of sudden death using an historical claims-based study and compared these results to current ICD usage volumes...
  26. ncbi request reprint Effect of surgical revascularization in patients with coronary artery disease and ventricular tachycardia or fibrillation in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry
    James R Cook
    Division of Cardiology, Department of Medicine, Baystate Medical Center, Springfield, MA 01199, USA
    Am Heart J 143:821-6. 2002
    ..The magnitude of benefit attributed to revascularization has varied by study, and the use of adjunct implantable cardioverter defibrillator (ICD) therapy has not been well-characterized...
  27. ncbi request reprint Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial
    Bruce L Wilkoff
    The Cleveland Clinic Foundation, 9500 Euclid Ave, Desk F 15, Cleveland, OH 44195, USA
    JAMA 288:3115-23. 2002
    ..Most currently implanted ICD devices provide dual-chamber pacing therapy. The most common comorbid cause for mortality in this population is congestive heart failure...
  28. doi request reprint Effect of pacing for soft indications on mortality and heart failure in the dual chamber and VVI implantable defibrillator (DAVID) trial
    Steven P Kutalek
    Drexel University College of Medicine, Philadelphia, Pennsylvania, USA
    Pacing Clin Electrophysiol 31:828-37. 2008
    ..Many patients had abnormalities for which pacing is often advocated to improve the management of ventricular dysfunction...
  29. ncbi request reprint Measuring survival rates from sudden cardiac arrest: the elusive definition
    Michael R Sayre
    Department of Emergency Medicine, The Ohio State University, 150 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA
    Resuscitation 62:25-34. 2004
    ..The definition of OOH-CA survival rates depends both upon the numerator (surviving cases) and the denominator (all cases)...
  30. ncbi request reprint A history of heart failure predicts arrhythmia treatment efficacy: data from the Antiarrythmics versus Implantable Defibrillators (AVID) study
    Michael A Brodsky
    Kaiser Permanente, Honolulu, HI
    Am Heart J 152:724-30. 2006
    ..In survivors of life-threatening ventricular tachycardia (VT), a history of CHF (HxCHF) before the VT episode may provide different prognostic information than their measured left ventricular ejection fraction (LVEF)...
  31. ncbi request reprint Location of cardiac arrests in the public access defibrillation trial
    David B Reed
    Department of Emergency Medicine, State University of New York, Upstate Medical University, Syracuse, NY, USA reeddahscyr edu
    Prehosp Emerg Care 10:61-76. 2006
    ....
  32. ncbi request reprint Analysis of implantable cardioverter defibrillator therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial
    Richard C Klein
    Cardiology Division, University of Utah Health Sciences Center and VA Medical Center, 50 N Medical Drive, Salt Lake City, UT 84132, USA
    J Cardiovasc Electrophysiol 14:940-8. 2003
    ..Arrhythmia recurrence rates in these patients are high, but which patients will receive a therapy and the forms of arrhythmia recurrence (VT or VF) are poorly understood...
  33. ncbi request reprint Prognostic value of baseline electrophysiology studies in patients with sustained ventricular tachyarrhythmia: the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial
    Michael A Brodsky
    Division of Cardiology, University of California Irvine Medical Center, Orange, Calif 92868 4080, USA
    Am Heart J 144:478-84. 2002
    ..We sought to determine the value of electrophysiology (EP) testing in patients with ventricular fibrillation (VF), ventricular tachycardia (VT) with syncope, or sustained VT in the setting of left ventricular dysfunction...
  34. ncbi request reprint Percent right ventricular pacing predicts outcomes in the DAVID trial
    Arjun D Sharma
    Regional Cardiology Associates, Sacramento, California 95819, USA
    Heart Rhythm 2:830-4. 2005
    ..Pacing was more frequent in the DDDR group...
  35. ncbi request reprint Are lipid-lowering drugs also antiarrhythmic drugs? An analysis of the Antiarrhythmics versus Implantable Defibrillators (AVID) trial
    L Brent Mitchell
    Division of Cardiology, Foothills Hospital University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada T2N 2T9
    J Am Coll Cardiol 42:81-7. 2003
    ....