Research TopicsSpecies | MARY HALLORANSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivoMarc A Wolman
Department of Zoology, and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin 53706, USA
Neural Dev 3:6. 2008..We have taken advantage of the unique features of the zebrafish embryo to visualize dynamic growth cone behaviors and analyze guidance mechanisms of axons emerging from a central brain nucleus in vivo...- In vivo imaging of cell behaviors and F-actin reveals LIM-HD transcription factor regulation of peripheral versus central sensory axon developmentErica F Andersen
Genetics Training Program, University of Wisconsin, 1117 W, Johnson Street, Madison, WI 53706, USA
Neural Dev 6:27. 2011..To understand how neuronal morphogenesis is controlled in vivo and how LIM-HD transcription factor activity differentially regulates peripheral versus central axons, we used live imaging of axon behavior and F-actin distribution in vivo... 
Repulsion or adhesion: receptors make the callMary C Halloran
Department of Zoology, Madison, WI 53706, USA
Curr Opin Cell Biol 18:533-40. 2006..Ephrin-Eph interactions can directly mediate cell adhesion and several mechanisms control whether ephrin-Eph binding and signaling induces repulsion or adhesion...- Current progress in neural crest cell motility and migration and future prospects for the zebrafish model systemMary C Halloran
Departments of Zoology and Anatomy and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin 53706, USA
Dev Dyn 228:497-513. 2003..The zebrafish is particularly well suited for the study of neural crest motility because of the ability to combine genetic manipulation with live imaging of migrating NCCs... - Rho-kinase and myosin II affect dynamic neural crest cell behaviors during epithelial to mesenchymal transition in vivoJason D Berndt
Department of Zoology, University of Wisconsin, Madison, WI 53706, USA
Dev Biol 324:236-44. 2008..These data reveal roles for myosin II and ROCK in NCC EMT in vivo, and provide a detailed characterization of NCC behavior during EMT that will form a basis for further mechanistic studies... - Semaphorin 3d promotes cell proliferation and neural crest cell development downstream of TCF in the zebrafish hindbrainJason D Berndt
Department of Zoology and Anatomy and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA
Development 133:3983-92. 2006..Finally, Sema3d overexpression rescues reduced proliferation caused by DeltaTCF expression, suggesting that Sema3d lies downstream of Wnt/TCF signaling in the molecular pathway thought to control cell cycle in NCC precursors... - Zebrafish bashful/laminin-alpha 1 mutants exhibit multiple axon guidance defectsJeremiah D Paulus
Department of Zoology, Cell and Molecular Biology Training Program, University of Wisconsin, Madison, Wisconsin, USA
Dev Dyn 235:213-24. 2006..In contrast to CNS axons, most peripheral axons appear normal in bal mutants. Our results, thus, reveal important and diverse functions for laminin-alpha1 in guiding developing axons in vivo... - The eye organizes neural crest cell migrationTobias Langenberg
Department of Zoology, University of Wisconsin, Madison, Wisconsin 53706, USA
Dev Dyn 237:1645-52. 2008..We show that, in chokh mutants, dorsal anterior NCC migration is severely disorganized. Time-lapse analysis shows that NCCs have significantly reduced migration rates and directionality in chokh mutants... - Repulsion and attraction of axons by semaphorin3D are mediated by different neuropilins in vivoMarc A Wolman
Department of Zoology and Anatomy, University of Wisconsin, Madison, Wisconsin 53706, USA
J Neurosci 24:8428-35. 2004..Together, these data support the hypothesis that Sema3D may act as a repellent through receptors containing Npn-1A and as an attractant via receptors containing Npn-1A and Npn-2B... - Semaphorin3D guides retinal axons along the dorsoventral axis of the tectumYan Liu
Department of Zoology and Anatomy, University of Wisconsin, Madison, Wisconsin 53706, USA
J Neurosci 24:310-8. 2004..These results suggest that Sema3D in the ventral tectum normally acts to inhibit ventral RGCs from extending into ventral tectum, ensuring their correct innervation of dorsal tectum... - Semaphorin3D regulates axon axon interactions by modulating levels of L1 cell adhesion moleculeMarc A Wolman
Department of Zoology, University of Wisconsin, Madison, Wisconsin 53706, USA
J Neurosci 27:9653-63. 2007..These results reveal a novel mechanism by which a semaphorin promotes fasciculation and modulates axon-axon interactions by regulating an adhesion molecule... - Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafishJill A Sakai
Neuroscience Training Program, Department of Zoology, University of Wisconsin, Madison, WI 53706, USA
Development 133:1035-44. 2006..Our results indicate that a proper balance of Sema3d is needed at the midline for the progression of RGC axons from the chiasm midline into the contralateral optic tract... - Central and peripheral axon branches from one neuron are guided differentially by Semaphorin3D and transient axonal glycoprotein-1Yan Liu
Department of Zoology, University of Wisconsin, Madison, Wisconsin 53706, USA
J Neurosci 25:10556-63. 2005.... - Developmental expression of sema3G, a novel zebrafish semaphorinCraig B Stevens
Department of Zoology, University of Wisconsin, Madison, 53706, USA
Gene Expr Patterns 5:647-53. 2005..These results provide a basis for studying how expression of multiple semaphorins could be essential for aspects of early development... - Muscle contractions guide rohon-beard peripheral sensory axonsJeremiah D Paulus
Departments of Zoology and Anatomy and Cell and Molecular Biology Training Program, University of Wisconsin, Madison, Wisconsin 53706, USA
J Neurosci 29:13190-201. 2009..This work suggests that the mechanical forces generated by muscle contractions are necessary for proper sensory axon pathfinding in vivo...
Research Grants
- Development of sensory axon pathways in zebrafishMary C Halloran; Fiscal Year: 2010..Moreover, knowledge of these mechanisms will help to understand the conditions under which axon regeneration after injury can occur. ..
- Development of sensory axon pathways in zebrafishMARY HALLORAN; Fiscal Year: 2009..Moreover, knowledge of these mechanisms will help to understand the conditions under which axon regeneration after injury can occur. ..
- Development of sensory axon pathways in zebrafishMARY HALLORAN; Fiscal Year: 2007..Moreover, knowledge of these mechanisms will help to understand the conditions under which axon regeneration after injury can occur. ..
- Zebrafish Development & Genetics ConferenceMARY HALLORAN; Fiscal Year: 2007....
- Sema3D Role in Retinal Axon Guidance and Cell MigrationMARY HALLORAN; Fiscal Year: 2006..Thus the proposed experiments will likely provide novel insights into how semaphorins regulate retinal axon development and neural crest cell migration within the complex in vivo environment. ..
- Development of sensory axon pathways in zebrafishMARY HALLORAN; Fiscal Year: 2009..Moreover, knowledge of these mechanisms will help to understand the conditions under which axon regeneration after injury can occur. ..