Franz Halberg

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi A chronomic tree of life: ontogenetic and phylogenetic 'memories' of primordial cycles--keys to ethics
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S1-11. 2004
  2. ncbi In remembrance of Eugene Ladislas Kanabrocki (18 April 1922 * 23 April 2009): a 'General' in the battle of penetrating the normal range and in revealing its relation to the cosmos
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    Clin Ter 160:375-86. 2009
  3. ncbi Prokaryotic and eukaryotic unicellular chronomics
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, Mayo Mail Code 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S192-202. 2005
  4. ncbi Season's appreciations 2001
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    Neuro Endocrinol Lett 23:170-87. 2002
  5. ncbi Chronomics of autism and suicide
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S100-8. 2005
  6. ncbi Blood pressure self-surveillance for health also reflects 1.3-year Richardson solar wind variation: spin-off from chronomics
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:58s-76s. 2003
  7. ncbi Chronoastrobiology: proposal, nine conferences, heliogeomagnetics, transyears, near-weeks, near-decades, phylogenetic and ontogenetic memories
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S150-87. 2004
  8. ncbi Cancer chronomics I. Origins of timed cancer treatment: early marker rhythm-guided individualized chronochemotherapy
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 6:55-61. 2006
  9. ncbi Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 6:73-84. 2006
  10. ncbi Chronomics, human time estimation, and aging
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Campus Mail Code 8609 MMC 8609, 420 Delaware St S E, Minneapolis, MN 55455, USA
    Clin Interv Aging 3:749-60. 2008

Collaborators

Detail Information

Publications85

  1. ncbi A chronomic tree of life: ontogenetic and phylogenetic 'memories' of primordial cycles--keys to ethics
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S1-11. 2004
    ....
  2. ncbi In remembrance of Eugene Ladislas Kanabrocki (18 April 1922 * 23 April 2009): a 'General' in the battle of penetrating the normal range and in revealing its relation to the cosmos
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    Clin Ter 160:375-86. 2009
    ..Germaine Cornélissen of the University of Minnesota, USA, and by Prof. Ramon C. Hermida of the University of Vigo, Spain...
  3. ncbi Prokaryotic and eukaryotic unicellular chronomics
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, Mayo Mail Code 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S192-202. 2005
    ....
  4. ncbi Season's appreciations 2001
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    Neuro Endocrinol Lett 23:170-87. 2002
  5. ncbi Chronomics of autism and suicide
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S100-8. 2005
    ..Just as spatial microscopy and electron microscopy resolved infectious agents, so does microscopy in time resolve the signature of environmental agents in human behavior in health and disease...
  6. ncbi Blood pressure self-surveillance for health also reflects 1.3-year Richardson solar wind variation: spin-off from chronomics
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:58s-76s. 2003
    ..Chronomically interpreted self-monitoring is a civic duty for both one's health and everybody's science...
  7. ncbi Chronoastrobiology: proposal, nine conferences, heliogeomagnetics, transyears, near-weeks, near-decades, phylogenetic and ontogenetic memories
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S150-87. 2004
    ..But there would have been enormous redundancy and confusion in assembling and piecing the information together. The waste of time and money involved in the redundancy and confusion would have been considerable. (ABSTRACT TRUNCATED)..
  8. ncbi Cancer chronomics I. Origins of timed cancer treatment: early marker rhythm-guided individualized chronochemotherapy
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 6:55-61. 2006
    ....
  9. ncbi Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 6:73-84. 2006
    ..More generally, the limits of knowledge are expanded by considering already mapped spectral components and their characteristics that can be influenced by the dynamics of heliogeomagnetic signals heretofore unassessed...
  10. ncbi Chronomics, human time estimation, and aging
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, Campus Mail Code 8609 MMC 8609, 420 Delaware St S E, Minneapolis, MN 55455, USA
    Clin Interv Aging 3:749-60. 2008
    ..Circadian rhythm stage affects many outcomes, including those of mental aging...
  11. ncbi Stress/strain/life revisited. Quantification by blood pressure chronomics: benetensive, transtensive or maletensive chrono-vasculo-neuro-immuno-modulation
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware St SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:136s-163s. 2003
    ..With reference to their historical context, here we rely only upon data which necessity, rather than philosophy, compels us to collect...
  12. ncbi Season's appreciations 2002 and 2003. Imaging in time: the transyear (longer-than-the-calendar year) and the half-year
    Franz Halberg
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Neuro Endocrinol Lett 24:479-98. 2003
  13. ncbi Engineering and governmental challenge: 7-day/24-hour chronobiologic blood pressure and heart rate screening: Part II
    Franz Halberg
    Halberg Chronobiology Center, 420 Delaware St. SE, University of Minnesota (Del Code 8609 Mayo, Minneapolis, MN 55455, USA
    Biomed Instrum Technol 36:183-97. 2002
  14. ncbi Transient circadian hyper-amplitude-tension (CHAT) may be intermittent: case reports illustrating gliding spectral windows
    George Katinas
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:104s-109s. 2003
    ....
  15. ncbi No baseline for blood pressure in ordinary life: another case of transient chronome alterations
    Tina Sarabandi
    Department of Electrical Engineering and Computer Science, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S107-10. 2004
    ..Whatever the underlying mechanisms of a long series of abnormal records may be, a 'baseline' can include weeklong spans of abnormality and is best replaced by comparisons with chronomic reference values...
  16. ncbi System times and time horizons for biospheric near-matches of primarily non-photic environmental cycles
    Franz Halberg
    University of Minnesota, Minneapolis, Minnesota, USA
    Biomed Pharmacother 56:266s-272s. 2002
    ....
  17. ncbi Engineering and governmental challenge: 7-day/24-hour chronobiologic blood pressure and heart rate screening: Part I
    Franz Halberg
    Halberg Chronobiology Center, 420 Delaware St. SE, University of Minnesota, Minneapolis, MN 55455, USA
    Biomed Instrum Technol 36:89-122. 2002
    ....
  18. ncbi Effects of diaphragmatic breathing on ambulatory blood pressure and heart rate
    John S Lee
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:87s-91s. 2003
    ..HR may serve as a marker for DB timing, but the effect on HR of DB was only of borderline statistical significance in the subject investigated...
  19. ncbi Circasemiannual chronomics: half-yearly biospheric changes in their own right and as a circannual waveform
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, MMC 8689, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:45s-54s. 2003
    ..The similarity of cycle lengths in itself can only be a hint prompting the search for causal relations...
  20. ncbi Schedule shifts, cancer and longevity: good, bad or indifferent?
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 7:263-73. 2008
    ....
  21. ncbi 100 or 30 years after Janeway or Bartter, Healthwatch helps avoid 'flying blind'
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 58:S69-86. 2004
    ....
  22. ncbi Chronomics: circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond
    Franz Halberg
    University of Minnesota, Minneapolis, MN, USA
    J Exp Ther Oncol 3:223-60. 2003
    ..The study of rhythms and broader chronomes leads to a dynamic functional genomics, guided by imaging in time of free radicals and antioxidants, amongst many other variables...
  23. ncbi Opportunity of detecting pre-hypertension: worldwide data on blood pressure overswinging
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S152-7. 2005
    ..Priority should be given to the development of an unobtrusive and affordable device to automatically monitor BP and to analyze the data as-one-goes, so that cardiovascular disease risk can be prevented...
  24. ncbi Geomagnetics and society interact in weekly and broader multiseptans underlying health and environmental integrity
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, Minnesota, USA
    Biomed Pharmacother 56:319s-326s. 2002
    ..In the spectral element of the chronomes of geophysical and biospherical variability, there are natural near weeks,apart from any precise 7-day periodicity...
  25. ncbi Circadian hypo- and hyper-amplitude-tension (CHAT) associated with putative pheochromocytoma and 12-hourly phenoxybenzamine treatment
    L D Sabath
    Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA
    Biomed Pharmacother 58:S99-106. 2004
    ..All findings support the need for long-term monitoring of BP and HR that may account for controversy in earlier publications...
  26. ncbi Cancer chronomics II. Origins of timing cancer treatment
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Ther Oncol 6:63-72. 2006
    ..It illustrates his early dose- and circadian time-response curves, limited as yet by a 4-timepoint approach, provides a list of his publications, and offers a succinct overview of individualized marker rhythm-guided oncotherapy...
  27. ncbi Chronomics of tree rings for chronoastrobiology and beyond
    Sylvain Nintcheu-Fata
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:24s-30s. 2003
    ....
  28. ncbi About 7-day (circaseptan) and circadian changes in cold pressor test (CPT)
    Mary S Lee
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:39s-44s. 2003
    ....
  29. ncbi Multiple resonances among time structures, chronomes, around and in US. Is an about 1.3-year periodicity in solar wind built into the human cardiovascular chronome?
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Fiziol Cheloveka 30:86-92. 2004
    ..The presence of any approximately 1.3-year component in human blood pressure (BP) and heart rate (HR) and in mortality from myocardial infarction (MI) is tested and its relative prominence compared to the 1.0-year variation...
  30. ncbi Chronomics: imaging in time by phase synchronization reveals wide spectral-biospheric resonances beyond short rhythms
    Franz Halberg
    Halberg Chronobiology Center, Universoty of Minnesota, Minneapolis, MN, USA
    Neuro Endocrinol Lett 24:355-80. 2003
  31. ncbi Point and interval estimations of circadian melatonin ecphasia in Smith-Magenis syndrome
    Germaine Cornelissen
    Halberg Chronobiology Center, MMC 8609, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 57:31s-34s. 2003
    ..Whether a resetting of the circadian acrophase beyond providing melatonin for sleep improvement can provide benefit remains to be investigated...
  32. ncbi About-weekly variations in nocturia
    Germaine Cornelissen
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware St S E, Minneapolis, MN 55455, USA
    Biomed Pharmacother 58:S140-4. 2004
    ....
  33. ncbi Geographic and extraterrestrial aspects of morbidity and/or mortality patterns from myocardial infarction and stroke
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota, Mayo Mail Code 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S68-75. 2005
    ....
  34. ncbi Near-transyear in solar magnetism
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S5-9. 2005
    ..10 years is longer than that characterizing solar magnetism, and it may be paired with an about 0.9-year component to correspond to an about 10-year modulation in amplitude or phase of an about-yearly component...
  35. ncbi Cugini's syndrome in statu nascendi. Oratio contra morem prevalentem et pro chronobiologica ratione ad pressione sanguinis curandam. A plea against the prevailing custom and in favor of a chronobiological approach to treating blood pressure
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Clin Ter 160:e13-24. 2009
    ....
  36. ncbi Time microscopy of circadian expression of cardiac clock gene mRNA transcription: chronodiagnostic and chrono-therapeutic implications
    R B Sothern
    The Rhythmometry Lab, College of Biological Sciences, University of Minnesota, 1445 Gortner Avenue, St Paul, MN 55108, USA
    Clin Ter 160:ep25-34. 2009
    ..CGs in general and their importance to cardiovascular health, as well as to diagnosis and treatment of human disease, are reviewed...
  37. ncbi Why continued surveillance? Intermittent blood pressure and heart rate abnormality under treatment
    G S Katinas
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 59:S141-51. 2005
    ..Both MESOR-hypertension and CHAT (circadian hyper-amplitude-tension) can be intermittent conditions even under treatment, and treatment is best adjusted based on monitoring, rather than "flying blind"...
  38. ncbi The chronobiology of prostate-specific antigen (PSA): case report and chrono-metaanalysis
    F Halberg
    Chronobiology Laboratories, University of Minnesota, Minneapolis 55455, USA
    Anticancer Res 19:857-62. 1999
    ..The load associated with a biopsy is also evaluated by a cardiovascular response...
  39. ncbi Spin-offs from blood pressure and heart rate studies for health care and space research
    F Halberg
    Chronobiology Laboratories, University of Minnesota, Minneapolis 55455, USA
    In Vivo 13:67-76. 1999
    ..Reference data obtained for health care can also serve to give a better understanding of the relationship between the terrestrial biosphere and cosmoi near and far...
  40. ncbi Resonance of about-weekly human heart rate rhythm with solar activity change
    G Cornelissen
    University of Minnesota, Lyon Laboratories, Minneapolis 55455, USA
    Biologia (Bratisl) 51:749-56. 1996
    ....
  41. ncbi Blood pressure outcomes of dental patients screened chronobiologically: a seven-year follow-up
    E M Schaffer
    University of Minnesota, School of Medicine, Department of Preventive Sciences, Minneapolis 55455, USA
    J Am Dent Assoc 132:891-9. 2001
    ..Dentists can educate patients regarding the need for screening and for interpreting the results for variability, and contribute to their overall health by referring them to their physicians when treatment is indicated...
  42. ncbi The week, inherited in neonatal human twins, found also in geomagnetic pulsations in isolated Antarctica
    G Cornelissen
    University of Minnesota, Minneapolis, USA
    Biomed Pharmacother 55:32s-50s. 2001
    ..Like circadians, about-weekly features in environmental variables such as geomagnetic pulsations were genetically acquired in the course of evolution...
  43. ncbi Feedsidewards: intermodulation (strictly) among time structures, chronomes, in and around us, and cosmo-vasculo-neuroimmunity. About ten-yearly changes: what Galileo missed and Schwabe found
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, 715 Mayo Building, Mayo Mail Code 8609, 420 Delaware St S E, Minneapolis, MN 55455, USA
    Ann N Y Acad Sci 917:348-75. 2000
    ....
  44. ncbi The cosmos and CHAT, prompting blood pressure and heart rate monitoring for Dérer's week
    F Halberg
    Halberg Chronobiology Center, University of Minnesota, Minneapolis 55455, USA
    Bratisl Lek Listy 101:260-71. 2000
    ....
  45. ncbi The biological week and broader time structures (chronomes): in memory of Gunther Hildebrandt
    G Cornelissen
    Chronobiology Center, University of Minnesota, Minneapolis 55455, USA
    Percept Mot Skills 90:579-86. 2000
    ..Data illustrating the biological week and chronomes are presented in recognition of extensive work of G. Hildebrandt...
  46. ncbi Incidence of sudden cardiac death, myocardial infarction and far- and near-transyears
    F Halberg
    University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 59:S239-61. 2005
    ..2 and 2.0 years, again with the 95% CI covering neither of these lengths. Herein, we discuss near- and far-transyears more generally in the light of their background in physics and the concept of reciprocal cyclicities...
  47. ncbi Yearly and perhaps transyearly human natality patterns near the equator and at higher latitudes
    G Cornelissen
    Halberg Chronobiology Center, University of Minnesota MMC 8609, 420 Delaware Street SE, Minneapolis, Minnesota 55455, USA
    Biomed Pharmacother 59:S117-22. 2005
    ..They do not detract from the fact that in other longer data sets at higher latitudes, the calendar year, presumably reflecting climatic influences, dominates the spectrum...
  48. ncbi India revisited: a new hospital and center culminating multidecadal cooperation. From cancer chronoradiotherapy to routine cardiovascular chronotheranostics and further joint Indian-US and international BIOCOS research
    O Schwartzkopff
    Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA
    Biomed Pharmacother 59:S123-31. 2005
  49. ncbi Is motivation influenced by geomagnetic activity?
    S Starbuck
    University of Minnesota, Minneapolis, Minnesota, USA
    Biomed Pharmacother 56:289s-297s. 2002
    ....
  50. ncbi Relationship between correlation dimension and indices of linear analysis in both respiratory movement and electroencephalogram
    N Burioka
    Department of Laboratory Medicine, Halberg Chronobiology Center, University of Minnesota, 420 Delaware Street, S.E. Mayo Building, Room 733, Mayo Mail Code 8609, Minneapolis, MN 55455-0385, USA
    Clin Neurophysiol 112:1147-53. 2001
    ..Whether there is a direct coordination between brain and lungs or whether brainstem systems, including that of the cholinergic system, affect both respiration and cortex requires further investigation...
  51. ncbi Time microscopy for all kinds of data including circadian clock biology
    G S Katinas
    Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Biomed Pharmacother 59:S20-3. 2005
    ..Illustrations included herein from molecular biology apply equally to all aspects of transdisciplinary science...
  52. ncbi Ambulatory blood-pressure monitoring
    Germaine Cornelissen
    N Engl J Med 355:850; author reply 850-1. 2006
  53. ncbi Seven-day (24-h) ambulatory blood pressure monitoring, self-reported depression and quality of life scores
    Makoto Shinagawa
    Department of Medicine, Tokyo Women's Medical University, Daini Hospital, Tokyo, Japan
    Blood Press Monit 7:69-76. 2002
    ..The results indicate the role that psychological factors may play in the pathogenesis of cardiovascular disease. Therapeutic implications are suggested for primary and secondary prevention...
  54. ncbi Circadian blood pressure overswinging in a physically fit, normotensive African American woman
    Katarina T Borer
    Division of Kinesiology, University of Michigan, Ann Arbor 48109 2214, USA
    Am J Hypertens 15:827-30. 2002
    ..These results suggest beta1-adrenergic mediation of CHAT and its refractoriness to exercise training...
  55. ncbi A recent illustration of some essentials of circadian chronotherapy study design
    William Hrushesky
    J Clin Oncol 22:2971-2; author reply 2972. 2004
  56. ncbi Chronobiologically explored effects of Telmisartan
    Pavel Prikryl
    Masaryk University, Brno, Czech Republic
    Clin Exp Hypertens 27:119-28. 2005
    ..Any circadian-stage dependent effect of Micardis, with or without low-dose aspirin, will require monitoring over spans longer than a single day for a given treatment administration time...
  57. ncbi Prehypertensive and other variabilities also await treatment
    Franz Halberg
    Am J Med 120:e19-20; author reply e21-2. 2007
  58. ncbi Age-dependent association of exposure to television screen with children's urinary melatonin excretion?
    Roberto Salti
    Department of Pediatrics, University of Florence, Florence, Italy
    Neuro Endocrinol Lett 27:73-80. 2006
    ....
  59. ncbi Circadian heart rate and blood pressure variability considered for research and patient care
    Ram B Singh
    Medical Hospital and Research Center, Civil Lines, Moradabad, India
    Int J Cardiol 87:9-28; discussion 29-30. 2003
    ..To review mechanisms of circadian variations in heart rate variability (HRV) and blood pressure variability (BPV) and mortality and morbidity due to cardiovascular diseases (CVD)...
  60. ncbi Melatonin, refractory hypertension, myocardial ischemia and other challenges in nightly blood pressure lowering
    Rina Mikhailovna Zaslavskaya
    Department of Cardiology, Hospital 60, Moscow, Russia
    Biomed Pharmacother 58:S129-34. 2004
    ....
  61. ncbi About 21-year hale cyclic signature in agriculture complement those in biomedicine
    Crina Turtoi
    National Institute of Statistics, Bucharest, Romania
    Biomed Pharmacother 58:S12-4. 2004
    ..Transdisciplinary chronomics is advocated to systematically map predictable dynamics in agriculture such as Hale-like cycles in corn and soja and their interactions with chronomes of external environmental factors...
  62. ncbi Magnetic storm effect on the circulation of rabbits
    Sergey Mikhailovich Chibisov
    People's Friendship University of Russia, Moscow, Russia
    Biomed Pharmacother 58:S15-9. 2004
    ....
  63. ncbi Does exposure to an artificial ULF magnetic field affect blood pressure, heart rate variability and mood?
    Gen Mitsutake
    Division of Neurocardiology and Chronoecology, Tokyo Women s Medical University, Daini Hospital, Tokyo, Japan
    Biomed Pharmacother 58:S20-7. 2004
    ..005, -0.0001) in an early night exposure to the real magnetic field, but not in other circadian stages. There was no significant difference between circadian responses to real and sham exposure in any variable at any circadian stage...
  64. ncbi Non-photic, non-thermic circadecadal solar cycle interaction with cardiovascular circannual and circasemiannual variation in heated air-conditioned habitat
    Yoshihiko Watanabe
    Department of Medicine, Tokyo Women s Medical University, Daini Hospital, Nishiogu 2 1 10 Arakawa ku, Tokyo 116 8567, Japan
    Biomed Pharmacother 57:55s-57s. 2003
    ..The beating of the transannual and circannual components documented on another data series may contribute to the lack of a consistent 1-year synchronized circannual variation in this case and many others...
  65. ncbi Marriage and divorce over a century in Japan: social biomedicine, not yet societal therapy
    Takashi Yamanaka
    Department of Medicine, Tokyo Women s Medical University Tokyo, Japan
    Biomed Pharmacother 56:314s-318s. 2002
    ....
  66. ncbi Clinical chronobiology and chronome-geriatrics at variance with recommendations of subsequent guidelines, yet focusing indeed on pre-hypertension in the physiological range
    Kuniaki Otsuka
    Department of Medicine, Daini Hospital, Tokyo Women's Medical University, Nishiogu 2-1-10 Arakawa-ku, Tokyo 116-8567, Japan
    Biomed Pharmacother 57:164s-198s. 2003
  67. ncbi Effects of autogenic training and antihypertensive agents on circadian and circaseptan variation of blood pressure
    Yoshihiko Watanabe
    Tokyo Women s Medical University, Tokyo, Japan
    Clin Exp Hypertens 25:405-12. 2003
    ..Prospective outcome studies are needed to assess whether the relative merits of these treatments are in keeping with their effects on blood pressure and blood pressure variability...
  68. ncbi Thousands of blood pressure and heart rate measurements at fixed clock hours may mislead
    Yoshihiko Watanabe
    Department of Medicine I, Division of Neurocardiology, Tokyo Women's Medical University, Tokyo, Japan
    Neuro Endocrinol Lett 24:339-40. 2003
    ..The diagnoses of summer or winter hypertension in one and the same person can depend upon the clock hour of measurement...
  69. ncbi Transyears: new endpoints for gerontology and geriatrics or confusing sources of variability?
    Franz Halberg
    J Gerontol A Biol Sci Med Sci 59:1344-7. 2004
  70. ncbi Losartan-ramipril combination treatment
    R B Singh
    J Assoc Physicians India 52:429. 2004
  71. ncbi Toward chronocardiologic and chronomic insights: dynamics of heart rate associated with head-up tilting
    Yutaka Kubo
    Department of Medicine, Daini Hospital, Tokyo Women s Medical University, Nishiogu 2 1 10 Arakawa ku, Tokyo 116 8567, Japan
    Biomed Pharmacother 57:110s-115s. 2003
    ..5 s, cycles with very much lower frequencies, along the scales of hours and even years, that critically modulate the mislabeled (only relatively high- and low-frequency) components in the range of seconds or minutes...
  72. ncbi Circadian phase difference of leptin in android versus gynoid obesity
    Federico Perfetto
    Department of Internal Medicine, Facolta di Medicina e Chirurgia, University of Florence, Viale Pieraccini 18, 50139 Florence, Italy
    Peptides 25:1297-306. 2004
    ..05). Understanding putative mechanisms underlying different body fat distribution may lead to improved chronotherapeutic measures...
  73. ncbi Impaired cardiovascular function predicts mortality from respiratory disorders in the elderly
    Kuniaki Otsuka
    Hypertens Res 31:589-91. 2008
  74. ncbi Neuropeptide chronomics in clinically healthy young adults: circaoctohoran and circadian patterns
    Alex Löckinger
    Department of Internal Medicine, University of Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Peptides 25:533-42. 2004
    ..Maps of circadian and extra-circadian patterns may serve for screening, diagnosis and a better understanding of mechanisms underlying the etiology of various diseases...
  75. ncbi Circadian telomerase activity and DNA synthesis for timing peptide administration
    Yi Qu
    Medical Center, Sichuan University, Sichuan, PR China
    Peptides 24:363-9. 2003
    ..These results provide a model for exploring optimal timing of chronotherapy with peptides, especially for treatment with telomerase inhibitors...
  76. ncbi Circaseptan aspects of self-assessed sleep protocols covering 70 nights on 33 clinically healthy persons
    Karl Hecht
    Department of Pathological Physiology, Humboldt University, Berlin, Germany
    Percept Mot Skills 95:258-66. 2002
    ..By virtue of their relative simplicity, they could be part of a protocol designed to assess pharmacologic or nonpharmacologic interventions of sleep disturbance aimed at restoring undisturbed sleep...
  77. ncbi Partial spectral element in the chronome of a human neonatal heart rate at term
    Yoshihiko Watanabe
    Tokyo Women s Medical University, Daini Hospital, Tokyo, Japan
    Biomed Pharmacother 56:374s-378s. 2002
    ..Dominating first are an about-weekly (circaseptan) or half-weekly (circasemiseptan) and an about 26-day (circatrigintan) component, with a subsequent change from infradian to circadian prominence...
  78. ncbi Circannual and/or transannual variations in growth hormone and beyond--call for long data series
    Cristina Gobello
    Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina
    Biomed Pharmacother 58:S87-90. 2004
    ..3 and 1.0 year, respectively, suggests the desirability of analyzing available time series on variables of interest in biomedicine, to explore heretofore unknown longer-than-yearly cycles that may interact (beat) with yearly ones...
  79. ncbi Biological rhythms and behavior--then and now
    Otto Appenzeller
    New Mexico Health Enhancement and Marathon Clinics Research Foundation, Albuquerque, NM 87122 1424, USA
    Med Sci Monit 8:SR27-30. 2002
    ..This fossil record can be compared with contemporary enamel thus providing insight into an ancient biological rhythm, and consequently into behavior in pre-historic civilizations...
  80. ncbi Chaos and chronos in the human brain: a tribute to Franz Halberg
    Olga Quadens
    IASB BIRA, Brussels, Belgium, 14, Avenue Alberrtijn, B 1200 Brussels, Belgium
    Biomed Pharmacother 56:379s-382s. 2002
    ..With increasing age, with the accumulation of structured information, the order-to-noise ratio increases, suggesting that for a while during growth, the making of order out of chaos may define the course of development in time...
  81. ncbi Time structures, chronomes, of soldiers' stature mimicking Hale cycle in neonatal body length
    John Komlos
    University of Munich, Department of Economics, Munich, Germany
    Biomed Pharmacother 58:S135-9. 2004
    ....
  82. ncbi Selected contribution: circadian rhythm of tumor necrosis factor-alpha uptake into mouse spinal cord
    Weihong Pan
    Department of Medicine, Tulane University and the Veterans Affairs Medical Center, New Orleans, Louisiana 70112 1262, USA
    J Appl Physiol 92:1357-62; discussion 1356. 2002
    ..The circadian rhythm of the influx of TNF-alpha into this region of the CNS suggests a functional role for the spinal cord in the physiological actions of TNF-alpha...
  83. ncbi A few more points on chronobiology
    Franz Halberg
    Minn Med 89:6. 2006
  84. ncbi Circadian gene mPer2 overexpression induces cancer cell apoptosis
    Hui Hua
    Health Ministry Key Laboratory of Chronobiology, West China Medical Center, Sichuan University, Chengdu, 610041, China
    Cancer Sci 97:589-96. 2006
    ..Our results suggest that the circadian gene mPeriod2 may play an important role in tumor suppression by inducing apoptotic cell death, which is attributable to enhanced pro-apoptotis signaling and attenuated anti-apoptosis processes...
  85. ncbi Chronobiology predicts actual and proxy outcomes when dipping fails
    Germaine Cornelissen
    Hypertension 49:237-9. 2007