Research Topics
| Ganesh V HaladeSummaryAffiliation: University of Texas Health Science Center Country: USA Publications
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Detail Information
Publications
Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, TX 78229 3900, USA
Pharmacol Res 63:300-7. 2011..Our results suggest that RSG treatment has context-dependent effects on cardiac remodeling and serves a negative cardiac role when given with a corn oil enriched diet...
Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Texas 78229 3900, USA
Exp Gerontol 46:43-52. 2011..This inflammation may consequently increase osteoclastogenesis, while reducing osteoblast development in CO-fed mice...
Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
J Nutr Biochem 22:459-69. 2011..Therefore, CLA with FO combination might be a novel dietary supplement to reduce fat mass and improve BMD...
t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposityMd M Rahman
Department of Medicine, University of Texas Health Science Center at San Antonio, Texas 78229 3900, USA
J Cell Physiol 226:2406-14. 2011..In conclusion, these findings suggest that t10c12-CLA is the most potent CLA isomer and it exerts its anti-osteoporotic effect by modulating osteoclastogenesis and bone marrow adiposity...
High fat diet-induced animal model of age-associated obesity and osteoporosisGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center at San Antonio, TX 78229 3900, USA
J Nutr Biochem 21:1162-9. 2010....
Effect of CLA isomers and their mixture on aging C57Bl/6J miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
Eur J Nutr 48:409-18. 2009..The combined effect of CLA isomers have been studied extensively in animals and humans, however, the role of individual isomers remains unraveled...
Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
J Nutr Biochem 21:332-7. 2010..The t10c12 isomer is found to reduce the fat mass and increase the lean mass but significantly contributed to increase insulin resistance and liver steatosis, whereas c9t11 isomer prevented the insulin resistance...
DHA derivatives of fish oil as dietary supplements: a nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicityYonggang Ma
The University of Texas Health Science Center at San Antonio, Division of Geriatrics, Gerontology and Palliative Medicine, Department of Medicine, San Antonio, TX 78245, USA
Expert Opin Drug Discov 7:711-21. 2012..Novel nutritional-based drug discoveries of DHA derivatives or metabolites may provide realistic and alternative strategies for the treatment of metabolic and cardiovascular disease...
Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone miceGanesh V Halade
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
J Immunol 184:5280-6. 2010....
The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted dietMizanur Rahman
Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
Oxid Med Cell Longev 2:307-16. 2009..These data suggest that n-3 FA along with moderate CR may prolong lifespan by attenuating inflammation and oxidative stress...
Extracellular matrix and fibroblast communication following myocardial infarctionYonggang Ma
San Antonio Cardiovascular Proteomics Center, Barshop Institute for Longevity and Aging Studies, Division of Geriatrics, Gerontology and Palliative Medicine, Department of Medicine, The University of Texas Health Science Center at San Antonio, 15355 Lambda Drive, MC 7755, San Antonio, TX 78245, USA
J Cardiovasc Transl Res 5:848-57. 2012..In addition, we discuss future research areas that are needed to better understand the molecular mechanisms of ECM action, both in general and as a means to optimize infarct healing...
Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle lossM Rahman
Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, TX 78229 3900, USA
Biochem Biophys Res Commun 383:513-8. 2009..Thus, CLA may be a novel dietary supplement that will prevent sarcopenia by maintaining redox balance during aging...
