CHRISTOPHER ALAN HAIMAN

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, United States of America
    PLoS Genet 9:e1003419. 2013
  2. pmc Levels of beta-microseminoprotein in blood and risk of prostate cancer in multiple populations
    Christopher A Haiman
    Harlyne Norris Research Tower, 1450 Biggy St, Rm 1504, Los Angeles, CA 90033, USA
    J Natl Cancer Inst 105:237-43. 2013
  3. pmc Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Diabetes 61:1642-7. 2012
  4. pmc Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort
    Christy G Woolcott
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res 11:R10. 2009
  5. pmc Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study
    Sarah J Lord
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Breast Cancer Res 7:R336-44. 2005
  6. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
  7. pmc A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort
    Sulggi A Lee
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    BMC Med Genet 8:72. 2007
  8. pmc Variation in genetic admixture and population structure among Latinos: the Los Angeles Latino eye study (LALES)
    Corina J Shtir
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    BMC Genet 10:71. 2009
  9. pmc Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    Federico Canzian
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Cancer 9:257. 2009
  10. doi request reprint Exploring genetic susceptibility to cancer in diverse populations
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
    Curr Opin Genet Dev 20:330-5. 2010

Detail Information

Publications48

  1. pmc Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, United States of America
    PLoS Genet 9:e1003419. 2013
    ..Very large sample sizes will be required to better define the role of rare and less penetrant coding variation in prostate and breast cancer disease genetics...
  2. pmc Levels of beta-microseminoprotein in blood and risk of prostate cancer in multiple populations
    Christopher A Haiman
    Harlyne Norris Research Tower, 1450 Biggy St, Rm 1504, Los Angeles, CA 90033, USA
    J Natl Cancer Inst 105:237-43. 2013
    ..Whether MSP levels are predictive of prostate cancer risk has not been evaluated...
  3. pmc Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Diabetes 61:1642-7. 2012
    ..Fine-mapping of all loci will be required to reveal markers of risk that are important within and across populations...
  4. pmc Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort
    Christy G Woolcott
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res 11:R10. 2009
    ..Mammographic density is a strong risk factor for breast cancer. Our objective was to examine its association with polymorphisms identifying breast cancer susceptibility loci that were ascertained in recent genome-wide association studies...
  5. pmc Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study
    Sarah J Lord
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Breast Cancer Res 7:R336-44. 2005
    ..Identifying genetic variants that determine increases in mammographic density in hormone users may be important in understanding hormonal carcinogenesis of the breast...
  6. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
    ..Here, we report on the results of a large and comprehensive study of the association between genetic variation in the AR gene and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)...
  7. pmc A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort
    Sulggi A Lee
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    BMC Med Genet 8:72. 2007
    ..Prospective epidemiological studies have also shown that women with higher circulating PRL levels have an increase in risk of breast cancer, suggesting that variability in PRL may also be important in determining a woman's risk...
  8. pmc Variation in genetic admixture and population structure among Latinos: the Los Angeles Latino eye study (LALES)
    Corina J Shtir
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    BMC Genet 10:71. 2009
    ..Sensitivity of ancestry estimates to relative sample size was considered...
  9. pmc Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    Federico Canzian
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Cancer 9:257. 2009
    ..We studied the association between breast cancer risk and polymorphisms in genes that code for GNRH1 and its receptor (GNRHR) in the large National Cancer Institute Breast and Prostate Cancer Cohort Consortium (NCI-BPC3)...
  10. doi request reprint Exploring genetic susceptibility to cancer in diverse populations
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
    Curr Opin Genet Dev 20:330-5. 2010
    ..Challenges to multiethnic studies relating to study power, control for hidden population structure, imputation, and use of shared controls for multiple cancer endpoints are discussed...
  11. pmc A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, USA
    Nat Genet 43:1210-4. 2011
    ..25, P = 1.1 × 10(-9)), particularly in younger women (<50 years of age) (OR = 1.48, P = 1.9 × 10(-9)). Our results identify a genetic locus associated with estrogen receptor negative breast cancer subtypes in multiple populations...
  12. pmc A common genetic risk factor for colorectal and prostate cancer
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Nat Genet 39:954-6. 2007
    ..Comprehensive testing in the region uncovered variants capturing significant additional risk. Our results show that variants at 8q24 have different effects on cancer development that depend on the tissue type...
  13. ncbi request reprint Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Hum Mol Genet 17:825-34. 2008
    ..The methods utilized in this study, applied to multiple populations, provide a framework for testing in association studies in diverse populations...
  14. pmc Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    BMC Cancer 9:43. 2009
    ....
  15. pmc Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, United States of America
    PLoS Genet 7:e1001387. 2011
    ..Our findings with variants at 8q24 also reinforce the importance of this region as a major risk locus for prostate cancer in men of African ancestry...
  16. ncbi request reprint A variant in the cytochrome p450 oxidoreductase gene is associated with breast cancer risk in African Americans
    Christopher A Haiman
    Departments of Preventive Medicine and Pathology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Res 67:3565-8. 2007
    ..03) and stronger in those with advanced disease (411 cases and 877 controls; OR, 2.60; 95% CI, 1.56-4.34; P = 0.0002). These data suggest that African Americans harbor an allele at the POR locus that may increase breast cancer risk...
  17. ncbi request reprint Common genetic variation at PTEN and risk of sporadic breast and prostate cancer
    Christopher A Haiman
    University of Southern California Norris Comprehensive Cancer Center, Room 4441, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 15:1021-5. 2006
    ..We found no strong association with any common haplotype in relation to breast or prostate cancer risk. In summary, our results show that common variants in PTEN do not substantially influence risk of these two common cancers...
  18. ncbi request reprint Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Cancer Res 67:1893-7. 2007
    ..Thus, although genetic variation in CYP19A1 produces measurable differences in estrogen levels among postmenopausal women, the magnitude of the change was insufficient to contribute detectably to breast cancer...
  19. pmc Ethnic differences in ovulatory function in nulliparous women
    C A Haiman
    Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA
    Br J Cancer 86:367-71. 2002
    ..8%, P=0.48; luteal oestradiol: +14.6%, P=0.04; luteal progesterone: +18.2%, P=0.06). These results suggest that exposure to endogenous steroid hormones may be greater for young African-American and Latina women than for Whites...
  20. pmc Genetic determinants of mammographic density
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Breast Cancer Res 4:R5. 2002
    ..Changes in breast density are highly correlated with steroid hormone exposure...
  21. ncbi request reprint Ethnic and racial differences in the smoking-related risk of lung cancer
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA 90089 9175, USA
    N Engl J Med 354:333-42. 2006
    ..There is remarkable variation in the incidence of lung cancer among ethnic and racial groups in the United States...
  22. ncbi request reprint Common genetic variation in the sex steroid hormone-binding globulin (SHBG) gene and circulating shbg levels among postmenopausal women: the Multiethnic Cohort
    Christopher A Haiman
    University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, California 90089, USA
    J Clin Endocrinol Metab 90:2198-204. 2005
    ....
  23. ncbi request reprint A comprehensive haplotype analysis of CYP19 and breast cancer risk: the Multiethnic Cohort
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, 1441 Eastlake Ave, Rm 4441, Los Angeles, CA 90089 9175, USA
    Hum Mol Genet 12:2679-92. 2003
    ..31; 95% CI, 1.11-1.54). Our findings suggest the hypothesis that women with the long-range CYP19 haplotype 2b-3c may be carriers of a predisposing breast cancer susceptibility allele...
  24. ncbi request reprint Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort
    Iona Cheng
    Department of Epidemiology and Biostatistics and Center for Human Genetics, University of California San Francisco, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 15:1993-7. 2006
    ..Our results suggest that common genetic variation in the IGFBP1 and IGFBP3 genes do not substantially influence prostate and breast cancer susceptibility...
  25. pmc Association of diabetes with prostate cancer risk in the multiethnic cohort
    Kevin M Waters
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, USA
    Am J Epidemiol 169:937-45. 2009
    ..Diabetes is a protective factor for prostate cancer across populations, suggesting shared risk factors that influence a common mechanism...
  26. pmc Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 18:242-7. 2009
    ..Our study provides evidence that CYP19A1 genetic variation influences susceptibility to endometrial cancer, particularly among older and obese women...
  27. pmc Multiple regions within 8q24 independently affect risk for prostate cancer
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Nat Genet 39:638-44. 2007
    ..None of the prostate cancer risk variants aligns to a known gene or alters the coding sequence of an encoded protein...
  28. ncbi request reprint Germ line variation at 8q24 and endometrial cancer risk
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Harlyne Norris Research Tower, 1450 Biggy Street, Room 1504A, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 16:2166-8. 2007
  29. pmc A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians
    Fredrick R Schumacher
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Hum Mol Genet 19:3089-101. 2010
    ....
  30. pmc Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
    Cancer Genet Cytogenet 181:16-9. 2008
    ..18, 95% CI = 0.76-1.82, P = 0.46). Our results do not support the hypothesis that the mtDNA G10398A polymorphism is, as has previously been reported, a marker of breast cancer risk in African Americans...
  31. pmc Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach
    Eunjung Lee
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Carcinogenesis 31:1392-9. 2010
    ..We investigated whether genetic variation in PGR is also associated with endometrial cancer risk using a haplotype-based approach...
  32. pmc Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations
    Jing He
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, Harlyne Norris Research Tower, 1450 Biggy Street, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 20:70-81. 2011
    ..Genome-wide association studies (GWAS) in populations of European ancestry have identified several loci that confer an increased risk of colorectal cancer (CRC)...
  33. pmc Established risk factors account for most of the racial differences in cardiovascular disease mortality
    Sean O Henderson
    Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 2:e377. 2007
    ..Cardiovascular disease (CVD) mortality varies across racial and ethnic groups in the U.S., and the extent that known risk factors can explain the differences has not been extensively explored...
  34. ncbi request reprint A systematic assessment of common genetic variation in CYP11A and risk of breast cancer
    Veronica Wendy Setiawan
    Departments of Preventive Medicine and Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Cancer Res 66:12019-25. 2006
    ..Based on these findings, CYP11A deserves further consideration as a candidate breast cancer susceptibility gene...
  35. ncbi request reprint Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study
    Daniel O Stram
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif 90033, USA
    Hum Hered 55:27-36. 2003
    ..A candidate set of htSNPS of a given size is chosen so as to maximize the minimum value of R2h over the common haplotypes, h...
  36. ncbi request reprint The relationship between twenty missense ATM variants and breast cancer risk: the Multiethnic Cohort
    Philip Bretsky
    University of Southern California Norris Comprehensive Cancer Center, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA
    Cancer Epidemiol Biomarkers Prev 12:733-8. 2003
    ..Although a single missense variant (L546V) appeared to act as a modest predictor of risk, the remaining variants were no more common in breast cancer cases as compared with controls...
  37. doi request reprint No association of risk variants for diabetes and obesity with breast cancer: the Multiethnic Cohort and PAGE studies
    Fang Chen
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 20:1039-42. 2011
    ..Body mass index is an established risk factor for postmenopausal breast cancer. Epidemiologic studies have also reported a positive association between type 2 diabetes (T2D) and breast cancer risk...
  38. ncbi request reprint Racial/ethnic differences in postmenopausal endogenous hormones: the multiethnic cohort study
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 15:1849-55. 2006
    ..Many of the differences in endogenous postmenopausal hormonal milieu across these five racial/ethnic groups are consistent with the known differences in breast cancer incidence across these populations...
  39. ncbi request reprint CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    Veronica Wendy Setiawan
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 16:2237-46. 2007
    ..Our findings do not support the hypothesis that common germ line variation in CYP17 makes a substantial contribution to postmenopausal breast or prostate cancer susceptibility...
  40. pmc Fine mapping of the association with obesity at the FTO locus in African-derived populations
    Mohamed T Hassanein
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
    Hum Mol Genet 19:2907-16. 2010
    ..This study illustrates the potential of using populations with different LD patterns to fine map associations and helps pave the way for genetically guided functional studies at the FTO locus...
  41. doi request reprint The role of established breast cancer susceptibility loci in mammographic density in young women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:258-60. 2008
  42. pmc A systematic approach to understand the functional consequences of non-protein coding risk regions
    Gerhard A Coetzee
    Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cell Cycle 9:256-9. 2010
    ..Here we describe an integrated framework to allow non-protein coding loci to be annotated with respect to regulatory functions. This will facilitate identification of target genes as well as prioritize variants for functional testing...
  43. ncbi request reprint Genetic variation in angiotensin I-converting enzyme (ACE) and breast cancer risk: the multiethnic cohort
    Christopher A Haiman
    Departments of Preventive Medicine, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
    Cancer Res 63:6984-7. 2003
    ..Overall, these results suggest that the A-240T and I/D ACE polymorphisms are not likely to be strong predictors of breast cancer risk...
  44. pmc Generalizability of associations from prostate cancer genome-wide association studies in multiple populations
    Kevin M Waters
    Harlyne Norris Research Tower, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 18:1285-9. 2009
    ..For many of these regions, fine-mapping in non-European samples may help localize causal alleles and better determine their contribution to prostate cancer risk in the population...
  45. ncbi request reprint Multiple Polymorphisms in the renin- angiotensin-aldosterone system (ACE, CYP11B2, AGTR1) and their contribution to hypertension in African Americans and Latinos in the multiethnic cohort
    Sean O Henderson
    Department of Emergency Medicine, Keck School of Medicine, University of Southern California Los Angeles, CA 90033, USA
    Am J Med Sci 328:266-73. 2004
    ....
  46. ncbi request reprint Utilizing HapMap and tagging SNPs
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Methods Mol Med 141:37-54. 2008
    ....
  47. ncbi request reprint Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer
    Wu Zhang
    Division of Medical Oncology, Department of Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA
    J Clin Oncol 25:3726-31. 2007
    ..We tested the hypothesis of whether these two polymorphisms are associated with sex-specific clinical outcome in metastatic colon cancer patients treated with FU-based chemotherapy...
  48. pmc Functional enhancers at the gene-poor 8q24 cancer-linked locus
    Li Jia
    USC Norris Cancer Center, Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
    PLoS Genet 5:e1000597. 2009
    ....

Research Grants5

  1. A Comprehensive Analysis of Genetic Variation in DNA Repair Genes in Relation to
    Christopher Haiman; Fiscal Year: 2007
    ..The ability to accurately identify high-risk sub-groups may have profound implications on endometrial cancer prevention as well as advance research aimed at targeted drug development. ..
  2. Fine-mapping of 8q24 and Loci Identified in Genome-Wide Studies for Breast & Colo
    Christopher Haiman; Fiscal Year: 2009
    ..We expect findings from this work to guide the development of future preventive, early detection and prognostic strategies ..
  3. Fine-mapping of 8q24 and Loci Identified in Genome-Wide Studies for Breast & Colo
    CHRISTOPHER ALAN HAIMAN; Fiscal Year: 2010
    ..We expect findings from this work to guide the development of future preventive, early detection and prognostic strategies ..