J G Hacia

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells
    Ann B Moser
    Department of Biochemistry and Molecular Biology, Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA 90089, USA
    Lipids Health Dis 12:10. 2013
  2. pmc Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
    Zhong Wang
    Pharmacyclics, Inc, Sunnyvale, California, USA
    Mol Cancer 6:9. 2007
  3. pmc Human and great ape red blood cells differ in plasmalogen levels and composition
    Ann B Moser
    Hugo W Moser Research Institute at Kennedy Krieger, and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Lipids Health Dis 10:101. 2011
  4. pmc Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions
    Paul A Watkins
    Department ofNeurology, Johns Hopkins University School of Medicine, Hugo W Moser Research Institute at Kennedy Krieger, Baltimore, MD 21205, USA
    BMC Physiol 10:19. 2010
  5. pmc mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft
    Darren Magda
    Department of Biochemistry and Molecular Biology, University of Southern California, 2250 Alcazar Street, IGM 240, Los Angeles, CA 90089, USA
    BMC Genomics 9:521. 2008
  6. ncbi Genome of the apes
    J G Hacia
    The Institute for Genetic Medicine, University of Southern California, 2250 Alcazar Street, IGM 240, Los Angeles, CA 90089, USA
    Trends Genet 17:637-45. 2001
  7. ncbi Molecular pathology of head and neck cancer
    D L Crowe
    Center for Craniofacial Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Histol Histopathol 17:909-14. 2002

Collaborators

  • Steven J Steinberg
  • Jody Hey
  • Laura A Cox
  • D L Crowe
  • Uttam K Sinha
  • John J Ely
  • Ann B Moser
  • Oliver A Ryder
  • Paul A Watkins
  • Mazen W Karaman
  • Krishna Ramaswamy
  • Kimberly D Siegmund
  • Darren Magda
  • Hugo W Moser
  • Patricia K Dranchak
  • D Rick Lee
  • Patricia Thiemann
  • Xuan Ma
  • Zhong Wang
  • Junsong Zhao
  • Cicely B Toomer
  • Donna M Toleno
  • Julia Prescott
  • Philip Lecane
  • Brian L Pike
  • Jonathan L Sessler
  • Philip S Lecane
  • Dale Miles
  • Dong Gyu Cho
  • Louie Naumovski
  • Danielle Tonev
  • Cecilia Cortez
  • Samantha M Yeligar
  • Richard A Miller
  • Qing Fan

Detail Information

Publications7

  1. pmc Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells
    Ann B Moser
    Department of Biochemistry and Molecular Biology, Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA 90089, USA
    Lipids Health Dis 12:10. 2013
    ..In contrast, humans cannot derive PA from chlorophyll and instead normally obtain it only from meat, dairy, and fish products...
  2. pmc Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
    Zhong Wang
    Pharmacyclics, Inc, Sunnyvale, California, USA
    Mol Cancer 6:9. 2007
    ..However, the mechanisms for their anticancer activity have not been fully elucidated...
  3. pmc Human and great ape red blood cells differ in plasmalogen levels and composition
    Ann B Moser
    Hugo W Moser Research Institute at Kennedy Krieger, and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Lipids Health Dis 10:101. 2011
    ..Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease...
  4. pmc Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions
    Paul A Watkins
    Department ofNeurology, Johns Hopkins University School of Medicine, Hugo W Moser Research Institute at Kennedy Krieger, Baltimore, MD 21205, USA
    BMC Physiol 10:19. 2010
    ..Furthermore, phytanic acid is an activator of the PPAR-alpha transcription factor that influences the expression of genes relevant to lipid metabolism...
  5. pmc mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft
    Darren Magda
    Department of Biochemistry and Molecular Biology, University of Southern California, 2250 Alcazar Street, IGM 240, Los Angeles, CA 90089, USA
    BMC Genomics 9:521. 2008
    ..In order to address this issue, we characterized the gene expression profiles of A549 lung cancer cells and their mtDNA-depleted rho0 counterparts grown in culture and as tumor xenografts in immune-deficient mice...
  6. ncbi Genome of the apes
    J G Hacia
    The Institute for Genetic Medicine, University of Southern California, 2250 Alcazar Street, IGM 240, Los Angeles, CA 90089, USA
    Trends Genet 17:637-45. 2001
    ..Recent studies comparing the primate genomes have the potential to affect many aspects of human biomedical research and could benefit primate conservation efforts...
  7. ncbi Molecular pathology of head and neck cancer
    D L Crowe
    Center for Craniofacial Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Histol Histopathol 17:909-14. 2002
    ..This review will focus on the molecular changes which occur in these pathways and how they contribute to the pathogenesis of HNSCC...