Research Topics
Genomes and Genes | Mary N HaanSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
Socioeconomic position and incident mobility impairment in the Cardiovascular Health StudyCheryl K Nordstrom
Wayne State University, Center for Health Research, Detroit, MI, USA
BMC Geriatr 7:11. 2007..We investigated if personal socioeconomic position (SEP) factors and neighborhood characteristics were associated with incident mobility impairment in the elderly...
Effect of extrapyramidal signs and Lewy bodies on survival in patients with Alzheimer diseaseMary N Haan
Department of Epidemiology, University of Michigan, School of Public Health, 109 S Observatory St, Ann Arbor, MI 48109 2029, USA
Arch Neurol 59:588-93. 2002..Lewy bodies found at autopsy are not always correlated with EPSs during late life...- Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's diseaseMary N Haan
Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48104, USA
Nat Clin Pract Neurol 2:159-66. 2006..Clinical implications of the T2DM-AD link include cognitive evaluations of patients with T2DM, and potential benefits for such patients through treatment with statins or diabetes drugs that target insulin... - Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on AgingMary N Haan
Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
Am J Clin Nutr 85:511-7. 2007..High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline... - C-reactive protein and rate of dementia in carriers and non carriers of Apolipoprotein APOE4 genotypeMary N Haan
University of Michigan, School of Public Health, Epidemiology, Ann Arbor, MI 48104, United States
Neurobiol Aging 29:1774-82. 2008..Whether APOE4 modifies the effects of CRP on rate of all cause dementia, cognitive impairment or Alzheimer's disease (AD) is not established... - Can dementia be prevented? Brain aging in a population-based contextMary N Haan
University of Michigan, School of Public Health, Epidemiology, Ann Arbor, Michigan 48104, USA
Annu Rev Public Health 25:1-24. 2004..Understanding the reasons for differences between populations in genetic vulnerability and environmental exposures may help to identify modifiable risk factors that may lead to effective prevention of vascular and Alzheimer's dementia... - Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam StudyMary N Haan
Department of Epidemiology, University of Michigan, 611 Church Street, Ann Arbor, MI 48104, USA
Arch Ophthalmol 124:988-92. 2006..To determine the effectiveness of treatment with conjugated equine estrogens (CEE) or with CEE combined with progestin (CEE + P) on age-related macular degeneration (AMD)... - Prevalence of dementia in older latinos: the influence of type 2 diabetes mellitus, stroke and genetic factorsMary N Haan
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
J Am Geriatr Soc 51:169-77. 2003..To estimate dementia prevalence in older Mexican Americans, determine the distribution of dementia by etiology, and evaluate the contribution of type 2 diabetes mellitus, stroke, and apolipoprotein E (ApoE) genotype to dementia... - Impact of diabetes on cognitive function among older Latinos: a population-based cohort studyJasmanda H Wu
University of Michigan, School of Public Health, Department of Epidemiology, 611 Church St, Ann Arbor, MI 48104, USA
J Clin Epidemiol 56:686-93. 2003..10, 95% CI=-0.32, 0.11). CONCLUSIONS: More diabetic complications were associated with major cognitive decline among diabetic subjects. Research on long-term impact of treatment for type 2 diabetes is warranted... - Impact of antidiabetic medications on physical and cognitive functioning of older Mexican Americans with diabetes mellitus: a population-based cohort studyJasmanda H Wu
University of Michigan, School of Public Health, Epidemiology, Ann Arbor, MI 48109, USA
Ann Epidemiol 13:369-76. 2003..CONCLUSIONS: Antidiabetic drugs appear to be useful in alleviating the decline in physical and cognitive functioning among older Mexican Americans with diabetes, especially for those with a longer duration of the disease... 
Are health-related quality-of-life and self-rated health associated with mortality? Insights from Translating Research Into Action for Diabetes (TRIAD)Laura N McEwen
Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Prim Care Diabetes 3:37-42. 2009..To determine if health-related quality-of-life and self-rated health are associated with mortality in persons with diabetes...- C-reactive protein mediates the effect of apolipoprotein E on cytomegalovirus infectionAllison E Aiello
Dept of Epidemiology, Center for Social Epidemiology and Population Health, University of Michigan School of Public Health, 3659 SPH Tower, 109 Observatory, Ann Arbor, MI 48109 2029, USA
J Infect Dis 197:34-41. 2008..We examine whether APOE determines CMV and herpes simplex virus type 1 (HSV-1) antibody levels and assess whether C-reactive protein (CRP) mediates any observed relationships... - The PPAR-gamma Pro12Ala polymorphism and risk of cognitive impairment in a longitudinal studyNancy A West
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Neurobiol Aging 31:741-6. 2010..Male Ala carriers may also have a greater risk of dementia/CIND... - Persistent infection, inflammation, and functional impairment in older LatinosAllison E Aiello
Department of Epidemiology, Center for Social Epidemiology and Population Health, 1214 S University, 2nd Floor, Ann Arbor, MI 48104 2548, USA
J Gerontol A Biol Sci Med Sci 63:610-8. 2008..The objective of this study was to examine whether cytomegalovirus (CMV), herpes simplex virus type-1 (HSV-1), and C-reactive protein (CRP) are associated with functional impairment in older Latinos... - Neighborhood socioeconomic context and cognitive decline among older Mexican Americans: results from the Sacramento Area Latino Study on AgingAdina Zeki Al Hazzouri
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109 2029, USA
Am J Epidemiol 174:423-31. 2011..These results suggest that the effect of neighborhood SEP on cognitive decline among Latinos is primarily accounted for by education... - A multilevel intervention to increase community hospital use of alteplase for acute stroke (INSTINCT): a cluster-randomised controlled trialPhillip A Scott
Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA Stroke Program, University of Michigan, Ann Arbor, MI, USA Electronic address
Lancet Neurol 12:139-48. 2013..Several types of barrier frequently prevent its use. We assessed whether a standardised, barrier-assessment, multicomponent intervention could increase alteplase use in community hospitals in Michigan, USA... - Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-upEric T Roberts
Department of Epidemiology, 3659 SPH Tower, 109 Observatory, Ann Arbor, MI 48104 2548, USA
Am J Epidemiol 172:363-71. 2010..Further studies investigating methods for reducing IgG antibody response to CMV are warranted... - Attitudes and beliefs of Michigan emergency physicians toward tissue plasminogen activator use in stroke: baseline survey results from the INcreasing Stroke Treatment through INteractive behavioral Change Tactic (INSTINCT) trial hospitalsPhillip A Scott
Department of Emergency Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, PO Box 381, Ann Arbor, MI 48106 0381, USA
Stroke 41:2026-32. 2010..The objective of this study was to determine the baseline proportion of emergency physicians with favorable attitudes and beliefs toward intravenous tissue plasminogen activator (tPA) use in a cohort of randomly selected Michigan hospitals... - Body adiposity in late life and risk of dementia or cognitive impairment in a longitudinal community-based studyNancy A West
Department of Epidemiology, University of Michigan, Ann Arbor, 48104, USA
J Gerontol A Biol Sci Med Sci 64:103-9. 2009..The association between body adiposity at older ages and the development of cognitive impairment is unclear... - The association of blood pressure and mortality differs by self-reported walking speed in older LatinosMichelle C Odden
Epidemiology, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA
J Gerontol A Biol Sci Med Sci 67:977-83. 2012..We hypothesized that higher BP would be associated with greater mortality in high-functioning elders and lower mortality in elders with lower functional status... - Socioeconomic gradients in immune response to latent infectionJennifer Beam Dowd
Center for Social Epidemiology and Population Health, University of Michigan School of Public Health, Ann Arbor, MI 48104 2548, USA
Am J Epidemiol 167:112-20. 2008..It provides suggestive evidence that modulation of the immune system via latent infections may play a role in the observed associations between socioeconomic position and disease... - Hormone replacement therapy and cognitive performance: the role of homocysteineRachel A Whitmer
School of Public Health, University of California at Berkeley, Kaiser Permanente Medical Care Program, Oakland, USA
J Gerontol A Biol Sci Med Sci 58:324-30. 2003..The aim of this study was to examine whether the association between homocysteine and cognitive functioning varies by use of hormone replacement therapy (HRT) in postmenopausal women... - Risk factors for dementia in the cardiovascular health cognition studyLewis H Kuller
Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, PA 15261, USA
Neuroepidemiology 22:13-22. 2003..The Cardiovascular Health Cognition Study has evaluated the determinants of dementia among 3,608 participants that had a magnetic resonance imaging (MRI) of the brain in 1991 and were followed to 1998-1999... - Safety of intravenous thrombolytic use in four emergency departments without acute stroke teamsPhillip A Scott
Department of Emergency Medicine, University of Michigan, Ann Arbor, USA
Acad Emerg Med 17:1062-71. 2010..The objective was to evaluate safety of intravenous (IV) tissue plasminogen activator (tPA) delivered without dedicated thrombolytic stroke teams... - A semantic verbal fluency test for English- and Spanish-speaking older Mexican-AmericansHector M Gonzalez
University of Michigan, School of Public Health, Department of Epidemiology, 611 Church St, Room 315, Ann Arbor, MI 48104 2029, USA
Arch Clin Neuropsychol 20:199-208. 2005..Normative data tables stratified on demographic variables are also presented... - Antidepressant class and dosing among older Mexican Americans: application of geropsychiatric treatment guidelinesHector M Gonzalez
Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, Michigan 48104 2029, USA
Am J Geriatr Psychiatry 14:79-83. 2006..The objective of this study was to characterize patterns and correlates of antidepressant drugs (AD) among older Mexican Americans (MAs)... - Is the metabolic syndrome, with or without diabetes, associated with progressive disability in older Mexican Americans?Caroline S Blaum
The University of Michigan Medical School, and Ann Arbor Department of Veterans Affairs Medical Center GRECC, MI 48109 2007, USA
J Gerontol A Biol Sci Med Sci 62:766-73. 2007..The metabolic syndrome (MetS) is highly prevalent in the growing U.S. Latino population. We hypothesize that MetS, with or without diabetes, is associated with progressive disability in older Mexican Americans... - Risk factors for mortality among patients with diabetes: the Translating Research Into Action for Diabetes (TRIAD) StudyLaura N McEwen
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Diabetes Care 30:1736-41. 2007..We sought to examine demographic, socioeconomic, and biological predictors of all-cause, cardiovascular, and noncardiovascular mortality in patients with diabetes... - Diabetes as a predictor of change in functional status among older Mexican Americans: a population-based cohort studyJasmanda H Wu
Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor 48109, USA
Diabetes Care 26:314-9. 2003..CONCLUSIONS: There was lower baseline functional status and a more rapid decline in functional status among older Mexican Americans with diabetes versus those without diabetes... - A verbal learning and memory test for English- and Spanish-speaking older Mexican-American adultsHector M Gonzalez
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
Clin Neuropsychol 16:439-51. 2002..Normative data tables stratified on demographic variables are also presented... - Can vitamin supplements prevent cognitive decline and dementia in old age?Mary N Haan
Am J Clin Nutr 77:762-3. 2003 - Homocysteine and cognitive function in the Sacramento Area Latino Study on AgingJoshua W Miller
Department of Medical Pathology, School of Medicine, University of California, Davis, USA
Am J Clin Nutr 78:441-7. 2003.... - Plasma vitamin B-12 concentrations in an elderly latino population are predicted by serum gastrin concentrations and crystalline vitamin B-12 intakeAlison K Campbell
Department of Nutrition, Program in International Nutrition, University of California, Davis, CA, USA
J Nutr 133:2770-6. 2003..Crystalline vitamin B-12 intake predicted p-B12 in individuals with elevated serum gastrin, supporting IOM recommendations to increase consumption of crystalline vitamin B-12... - Everyday functioning in relation to cognitive functioning and neuroimaging in community-dwelling Hispanic and non-Hispanic older adultsSarah Tomaszewski Farias
Department of Neurology, School of Medicine, University of California, Davis, USA
J Int Neuropsychol Soc 10:342-54. 2004..The relationships between cognitive variables and functional status, as well as between the imaging variables and the IQCODE, did not differ across language-ethnic groups... - Correlates of memory function in community-dwelling elderly: the importance of white matter hyperintensitiesChristopher I Petkov
Center for Neuroscience, University of California at Davis, 95616, USA
J Int Neuropsychol Soc 10:371-81. 2004..We conclude that WMH are an important pathological substrate that affects certain memory functions in normal individuals and those with mild memory loss and discuss how tasks associated with WMH may rely upon frontal lobe function... - Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortificationMarisa I Ramos
Department of Pathology and Laboratory Medicine, University of California, Davis School of Medicine, Davis, USA
Am J Clin Nutr 80:1024-8. 2004..001). CONCLUSION: These data indicate that, despite folic acid fortification, low folate status is associated with depressive symptoms in elderly Latina women (but not elderly Latino men)... - Spanish and English Neuropsychological Assessment Scales (SENAS): further development and psychometric characteristicsDan Mungas
Department of Neurology, University of California, Davis, 4860 Y Street, Suite 3700, Sacramento, CA 95817, USA
Psychol Assess 16:347-59. 2004..Effects of DIF on scale-level ability scores were limited. Results demonstrate an empirically guided psychometric approach to test construction for multiethnic and multilingual test applications... - Comparing SF-36 scores across three groups of women with different health profilesKathleen J Yost
Center on Outcomes, Research and Education CORE, Evanston Northwestern Healthcare Research Institute, IL 60201, USA
Qual Life Res 14:1251-61. 2005..The widespread use of the Medical Outcomes Study (MOS) 36-item Short-Form Health Survey (SF-36) facilitates the comparison of health-related quality of life (HRQL) across independent studies... - Measurement of total vitamin B12 and holotranscobalamin, singly and in combination, in screening for metabolic vitamin B12 deficiencyJoshua W Miller
Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA 95817, USA
Clin Chem 52:278-85. 2006..Measurement of both holoTC and total vitamin B12 provides a better screen for vitamin B12 deficiency than either assay alone... - Spanish and English neuropsychological assessment scales: relationship to demographics, language, cognition, and independent functionDan Mungas
Department of Neurology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Neuropsychology 19:466-75. 2005.... - Education, income, occupation, and the 34-year incidence (1965-99) of Type 2 diabetes in the Alameda County StudySiobhan C Maty
School of Community Health, College of Urban and Public Affairs, Portland State University, PO Box 751, Portland, OR 97207 0751, USA
Int J Epidemiol 34:1274-81. 2005..Lower socioeconomic position (SEP) is related to higher prevalence of Type 2 diabetes, yet little is known about the relationship of SEP with incident diabetes... - Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on AgingMarisa I Ramos
School of Medicine, Department of Medical Pathology, University of California, Davis, USA
Am J Clin Nutr 82:1346-52. 2005..CONCLUSION: RBC folate is directly associated with cognitive function scores and is inversely associated with dementia in elderly Latinos despite folic acid fortification... - Fraction of total plasma vitamin B12 bound to transcobalamin correlates with cognitive function in elderly Latinos with depressive symptomsMarjorie G Garrod
Department of Medical Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, CA, USA
Clin Chem 54:1210-7. 2008..The fraction of total plasma vitamin B(12) bound to transcobalamin (holoTC/B12 ratio) may reflect tissue levels of the vitamin, but its clinical relevance is unclear...