Affiliation: University of Pennsylvania
- Correlates of functioning in bipolar disorderLaszlo Gyulai
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Psychopharmacol Bull 41:51-64. 2008..Our primary aim was to describe unique correlates of functioning in bipolar disorder (BD)...
- Bone mineral density in pre-and post-menopausal women with affective disorder treated with long-term L-thyroxine augmentationL Gyulai
Department of Psychiatry, Bipolar Disorders Unit, University of Pennsylvania Medical Center, 3600 Market Street, Room 800, Philadelphia, PA 19104, USA
J Affect Disord 66:185-91. 2001..This collaborative study investigates whether T4 augmentation for a minimum of 12 months decreases bone mineral density (BMD) in 26 pre- and post-menopausal women with affective disorder...
- Maintenance efficacy of divalproex in the prevention of bipolar depressionLaszlo Gyulai
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Neuropsychopharmacology 28:1374-82. 2003....
- A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study GroupC L Bowden
Department of Psychiatry, University of Texas Health Science Center at San Antonio, 78284 7792, USA
Arch Gen Psychiatry 57:481-9. 2000..This study compared the efficacy of divalproex, lithium, and placebo as prophylactic therapy...
- Premenstrual dysphoric disorder and psychiatric co-morbidityD R Kim
Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
Arch Womens Ment Health 7:37-47. 2004..The point prevalence of the co-occurrence of PMDD and other psychiatric disorders is discussed as well as implications for treatment and further study...
- Gender differences in bipolar disorder: retrospective data from the first 500 STEP-BD participantsClaudia F Baldassano
Bipolar Disorders Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Bipolar Disord 7:465-70. 2005..To examine gender differences in a large sample of patients with bipolar illness...
- The current understanding of lamotrigine as a mood stabilizerChang Gyu Hahn
Department of Psychiatry, University of Pennsylvania Medical Center, Philadelphia 19104, USA
J Clin Psychiatry 65:791-804. 2004..To examine whether lamotrigine has a unique role in the treatment of bipolar disorder, we evaluated the results of recent clinical trials and molecular and cell biological studies on lamotrigine...
- The prospective course of rapid-cycling bipolar disorder: findings from the STEP-BDChristopher D Schneck
Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80220, USA
Am J Psychiatry 165:370-7; quiz 410. 2008..In a naturalistic follow-up of adult bipolar patients, the authors examined the contributions of demographic, phenomenological, and clinical variables, including antidepressant use, to prospectively observed mood episode frequency...
- Prescription patterns of psychotropic medications in elderly compared with younger participants who achieved a "recovered" status in the systematic treatment enhancement program for bipolar disorderRayan K Al Jurdi
Department of Psychiatry, Baylor College of Medicine, Houston, Texas, USA
Am J Geriatr Psychiatry 16:922-33. 2008..This study compares prescription patterns between young adults and elderly with bipolar disorder who achieved a recovery status during the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)...
- Validity of the distinction between primary and secondary substance use disorder in patients with bipolar disorder: data from the first 1000 STEP-BD participantsMark D Fossey
Department of Psychiatry, University of Oklahoma College of Medicine Tulsa, Tulsa, Oklahoma 74135, USA
Am J Addict 15:138-43. 2006..The primary/secondary distinction for SUD is not valid when variations in the age of onset of the non-SUD are linked to course characteristics...
- Maintenance treatment outcomes in older patients with bipolar I disorderMartha Sajatovic
Department of Psychiatry, Case University School of Medicine and University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA
Am J Geriatr Psychiatry 13:305-11. 2005....
- Pharmacotherapy of bipolar disorder in old age: review and recommendationsRobert C Young
Payne Whitney, Westchester, and the Institute for Geriatric Psychiatry, Department of Psychiatry, Weill Medical College of Cornell University, 21 Bloomingdale Road, White Plains, New York 10605, USA
Am J Geriatr Psychiatry 12:342-57. 2004..Similarly, there are no systematic studies of the treatment of BP depression in elderly patients. The authors make suggestions for management and delineate priorities for research...
- Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophreniaHader A Mansour
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Bipolar Disord 11:701-10. 2009..The results are plausible, based on prior studies of circadian abnormalities. As replications have not been attempted uniformly, we evaluated representative, common polymorphisms in all three disorders...
- Pharmacologic management of psychosis in the elderly: a critical reviewNicholas Hoeh
University of Pennsylvania, Philadelphia 19104, USA
J Geriatr Psychiatry Neurol 16:213-8. 2003..This article reviews the efficacy of the pharmacologic management of psychotic symptoms in primary psychotic disorders, affective disorders, and neurodegenerative disorders...
- Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challengeLaszlo Gyulai
Bipolar Disorders Program, Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
Biol Psychiatry 53:899-905. 2003..Using lithium carbonate as a challenge to the hypothalamic-pituitary-thyroid (HPT) system, we determined whether patients with rapid-cycling BD are sensitive to the "antithyroid" properties of lithium...
- Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)Roy H Perlis
Bipolar Clinical and Research Program, Massachusetts General Hospital, ACC 812, 15 Parkman Street, Boston, MA 02114, USA
Am J Psychiatry 163:217-24. 2006..The authors looked for the features associated with risk of recurrence...
- Patient-based utilities for bipolar disorder-related health statesDennis A Revicki
Center for Health Outcomes Research, The MEDTAP Institute at United BioSource Corporation, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA
J Affect Disord 87:203-10. 2005..This study estimated health state utilities for hypothetical bipolar-related health states and patient's current health from bipolar I patients...
- Mood changes related to antidepressants: a longitudinal study of patients with bipolar disorder in a naturalistic settingMichael Bauer
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
Psychiatry Res 133:73-80. 2005..The primary difference in pattern between the groups was the time spent in depressed or normal mood, with minor daily mood variations...
- Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorderMichael Bauer
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Berlin, Germany
Bipolar Disord 6:67-74. 2004....
- Whole-genome association study of bipolar disorderP Sklar
Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
Mol Psychiatry 13:558-69. 2008..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...
- Sex-specific self-reported mood changes by patients with bipolar disorderNatalie Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2360, Palo Alto, CA 94305 5723, USA
J Psychiatr Res 39:77-83. 2005..While the prevalence of bipolar disorder I is similar between men and women, the clinical course may differ. This study investigated if there are differences in the clinical presentation of bipolar disorder between the sexes...
- Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement ProgramDavid J Miklowitz
Department of Psychology, University of Colorado, Boulder, CO 80309 0345, USA
Arch Gen Psychiatry 64:419-26. 2007..Psychosocial interventions have been shown to enhance pharmacotherapy outcomes in bipolar disorder...
- Effectiveness of adjunctive antidepressant treatment for bipolar depressionGary S Sachs
Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
N Engl J Med 356:1711-22. 2007..Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania...
- Menstrual dysfunction prior to onset of psychiatric illness is reported more commonly by women with bipolar disorder than by women with unipolar depression and healthy controlsHadine Joffe
Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Clin Psychiatry 67:297-304. 2006..However, it is not always clear whether such abnormalities, reflecting disruption of the hypothalamic-pituitary-gonadal (HPG) axis, are caused by psychotropic treatments or associated with the disorder per se...
- Does the use of an automated tool for self-reporting mood by patients with bipolar disorder bias the collected data?Michael Bauer
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Germany
MedGenMed 7:21. 2005..Automating data collection from patients can improve data quality, enhance compliance, and decrease costs in longitudinal studies. About half of all households in industrialized countries now have a home computer...
- Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporterHader A Mansour
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, U S A
Ann Med 37:590-602. 2005..Our analyses do not support association between SLC6A4 and BDI families. Further studies using sub-groups of BDI are worthwhile...