MARGARET GYETKO

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. request reprint
    Gyetko M, Sud S, Kendall T, Fuller J, Newstead M, Standiford T. Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection. J Immunol. 2000;165:1513-9 pubmed
    ..aeruginosa. This is the first report of a requirement for uPAR during cellular recruitment in vivo against a clinically relevant pathogen. ..
  2. request reprint
    Gyetko M, Sud S, Chen G, Fuller J, Chensue S, Toews G. Urokinase-type plasminogen activator is required for the generation of a type 1 immune response to pulmonary Cryptococcus neoformans infection. J Immunol. 2002;168:801-9 pubmed
    ..This study provides novel evidence that uPA is a critical modulator of immune responses and of immune cell effector functions in vivo. ..
  3. request reprint
    Gyetko M, Aizenberg D, Mayo Bond L. Urokinase-deficient and urokinase receptor-deficient mice have impaired neutrophil antimicrobial activation in vitro. J Leukoc Biol. 2004;76:648-56 pubmed
    ..We conclude that the uPA/uPAR system modulates several of the crucial steps in neutrophil activation that result in bacterial killing and effective innate host defense. ..

Locale

Collaborators

Detail Information

Publications3

  1. request reprint
    Gyetko M, Sud S, Kendall T, Fuller J, Newstead M, Standiford T. Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection. J Immunol. 2000;165:1513-9 pubmed
    ..aeruginosa. This is the first report of a requirement for uPAR during cellular recruitment in vivo against a clinically relevant pathogen. ..
  2. request reprint
    Gyetko M, Sud S, Chen G, Fuller J, Chensue S, Toews G. Urokinase-type plasminogen activator is required for the generation of a type 1 immune response to pulmonary Cryptococcus neoformans infection. J Immunol. 2002;168:801-9 pubmed
    ..This study provides novel evidence that uPA is a critical modulator of immune responses and of immune cell effector functions in vivo. ..
  3. request reprint
    Gyetko M, Aizenberg D, Mayo Bond L. Urokinase-deficient and urokinase receptor-deficient mice have impaired neutrophil antimicrobial activation in vitro. J Leukoc Biol. 2004;76:648-56 pubmed
    ..We conclude that the uPA/uPAR system modulates several of the crucial steps in neutrophil activation that result in bacterial killing and effective innate host defense. ..