Research Topics
Genomes and GenesSpecies | Katja GwinSummaryAffiliation: University of Chicago Country: USA Publications
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Detail Information
Publications
Epithelial-to-mesenchymal transition in metaplastic breast carcinomas with chondroid differentiation: expression of the E-cadherin repressor SnailKatja Gwin
Department of Pathology, University of Chicago, The University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637 1470, USA
Appl Immunohistochem Mol Morphol 18:526-31. 2010..E-cadherin expression was inversely correlated with active nuclear Snail expression. Our results suggest that EMT is induced in MBCD and may contribute to their frequent hematogenous metastasis...
Breast carcinoma with chondroid differentiation: a clinicopathologic study of 21 triple negative (ER-, PR-, Her2/neu-) casesKatja Gwin
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Int J Surg Pathol 18:27-35. 2010..Three patients subsequently died of metastatic disease...
Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiationKatja Gwin
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Int J Surg Pathol 19:20-5. 2011..In the absence of EGFR amplification, chromosome 7 aneusomy might be a useful criterion for the determination of potential candidates for EGFR tyrosine kinase inhibitor clinical trials...
Complementary value of the Ki-67 proliferation index to the oncotype DX recurrence scoreKatja Gwin
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Int J Surg Pathol 17:303-10. 2009..Therefore, the authors propose a combined evaluation of the RS and Ki-67 PI to identify tumors with high recurrence potential from the low-risk and intermediate-risk RS groups...
Insights into selected genetic diseases affecting the female reproductive tract and their implication for pathologic evaluation of gynecologic specimensKatja Gwin
Department of Pathology, University of Chicago, Chicago, Illinois 60637 1470, USA
Arch Pathol Lab Med 133:1041-52. 2009..Pathologists also receive more specimens requiring prospective workup for possible underlying genetic conditions such as microsatellite instability...
Clinico-pathologic comparison of type II endometrial cancers based on tamoxifen exposureAna I Tergas
Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, USA
Gynecol Oncol 127:316-20. 2012..To compare clinico-pathologic variables and protein expression of potential regulatory components in patients who develop type II endometrial cancer with and without antecedent tamoxifen...
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growthKristin M Nieman
Department of Obstetrics and Gynecology Section of Gynecologic Oncology, Center for Integrative Science, University of Chicago, Chicago, IL, USA
Nat Med 17:1498-503. 2011..These data indicate adipocytes provide fatty acids for rapid tumor growth, identifying lipid metabolism and transport as new targets for the treatment of cancers where adipocytes are a major component of the microenvironment...
Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1Benjamin Boyerinas
Feinberg School of Medicine, Division Hematology Oncology, Northwestern University, Chicago, IL 60611, USA
Int J Cancer 130:1787-97. 2012..Our data point at IMP-1 and MDR1 as indicators for response to therapy, and at IMP-1 as a novel therapeutic target for overcoming multidrug resistance of ovarian cancer...
FOXL2 and SOX9 distinguish the lineage of the sex cord-stromal cells in gonadoblastomasRebecca Buell-Gutbrod
Department of Pathology, University of Chicago, Chicago, IL, USA
Pediatr Dev Pathol 14:391-5. 2011....
Morphologic and other clinicopathologic features of endometrial clear cell carcinoma: a comprehensive analysis of 50 rigorously classified casesOluwole Fadare
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center Nashville, TN, USA Department of Obstetrics and Gynecology, Vanderbilt University Medical Center Nashville, TN, USA
Am J Cancer Res 3:70-95. 2013....
Sclerosing stromal tumor: an important differential diagnosis of ovarian neoplasms in childhood and adolescenceKatja Gwin
Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
Pediatr Dev Pathol 12:366-70. 2009....
Expanding the clinical spectrum of Frasier syndromeKatja Gwin
Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
Pediatr Dev Pathol 11:122-7. 2008....
