Katja Gwin

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint Epithelial-to-mesenchymal transition in metaplastic breast carcinomas with chondroid differentiation: expression of the E-cadherin repressor Snail
    Katja Gwin
    Department of Pathology, University of Chicago, The University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637 1470, USA
    Appl Immunohistochem Mol Morphol 18:526-31. 2010
  2. doi request reprint Breast carcinoma with chondroid differentiation: a clinicopathologic study of 21 triple negative (ER-, PR-, Her2/neu-) cases
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 18:27-35. 2010
  3. doi request reprint Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiation
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 19:20-5. 2011
  4. doi request reprint Complementary value of the Ki-67 proliferation index to the oncotype DX recurrence score
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 17:303-10. 2009
  5. doi request reprint Insights into selected genetic diseases affecting the female reproductive tract and their implication for pathologic evaluation of gynecologic specimens
    Katja Gwin
    Department of Pathology, University of Chicago, Chicago, Illinois 60637 1470, USA
    Arch Pathol Lab Med 133:1041-52. 2009
  6. pmc The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium
    Oluwole Fadare
    Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mod Pathol 26:1101-10. 2013
  7. doi request reprint Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility
    Oluwole Fadare
    Departments of Pathology, Microbiology and Immunology Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN Department of Pathology, University of Chicago, Chicago, IL Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT Department of Pathology and Laboratory Medicine, North Shore LIJ Health System and Hofstra North Shore LIJ School of Medicine, New Hyde Park, NY Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR Departments of Pathology Obstetrics and Gynecology, University of Arizona College of Medicine, Tucson, AZ Department of Pathology, Yale University School of Medicine, New Haven Department of Pathology, Bridgeport Hospital, Bridgeport, CT Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
    Am J Surg Pathol 38:189-96. 2014
  8. pmc Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance
    Oluwole Fadare
    Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Hum Pathol 44:1508-15. 2013
  9. doi request reprint Clinico-pathologic comparison of type II endometrial cancers based on tamoxifen exposure
    Ana I Tergas
    Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, USA
    Gynecol Oncol 127:316-20. 2012
  10. pmc Urokinase plasminogen activator system-targeted delivery of nanobins as a novel ovarian cancer therapy
    Yilin Zhang
    Corresponding Author Ernst Lengyel, Department of Obstetrics and Gynecology, University of Chicago, MC 2050, 5841 South Maryland Avenue, Chicago, IL 60637
    Mol Cancer Ther 12:2628-39. 2013

Collaborators

Detail Information

Publications17

  1. doi request reprint Epithelial-to-mesenchymal transition in metaplastic breast carcinomas with chondroid differentiation: expression of the E-cadherin repressor Snail
    Katja Gwin
    Department of Pathology, University of Chicago, The University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637 1470, USA
    Appl Immunohistochem Mol Morphol 18:526-31. 2010
    ..E-cadherin expression was inversely correlated with active nuclear Snail expression. Our results suggest that EMT is induced in MBCD and may contribute to their frequent hematogenous metastasis...
  2. doi request reprint Breast carcinoma with chondroid differentiation: a clinicopathologic study of 21 triple negative (ER-, PR-, Her2/neu-) cases
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 18:27-35. 2010
    ..Three patients subsequently died of metastatic disease...
  3. doi request reprint Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiation
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 19:20-5. 2011
    ..In the absence of EGFR amplification, chromosome 7 aneusomy might be a useful criterion for the determination of potential candidates for EGFR tyrosine kinase inhibitor clinical trials...
  4. doi request reprint Complementary value of the Ki-67 proliferation index to the oncotype DX recurrence score
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Surg Pathol 17:303-10. 2009
    ..Therefore, the authors propose a combined evaluation of the RS and Ki-67 PI to identify tumors with high recurrence potential from the low-risk and intermediate-risk RS groups...
  5. doi request reprint Insights into selected genetic diseases affecting the female reproductive tract and their implication for pathologic evaluation of gynecologic specimens
    Katja Gwin
    Department of Pathology, University of Chicago, Chicago, Illinois 60637 1470, USA
    Arch Pathol Lab Med 133:1041-52. 2009
    ..Pathologists also receive more specimens requiring prospective workup for possible underlying genetic conditions such as microsatellite instability...
  6. pmc The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium
    Oluwole Fadare
    Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mod Pathol 26:1101-10. 2013
    ..P53 expression may be a negative prognostic factor in this histotype, and warrants additional studies. Loss of BAF250a expression has no prognostic significance in endometrial clear cell carcinomas...
  7. doi request reprint Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility
    Oluwole Fadare
    Departments of Pathology, Microbiology and Immunology Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN Department of Pathology, University of Chicago, Chicago, IL Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT Department of Pathology and Laboratory Medicine, North Shore LIJ Health System and Hofstra North Shore LIJ School of Medicine, New Hyde Park, NY Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR Departments of Pathology Obstetrics and Gynecology, University of Arizona College of Medicine, Tucson, AZ Department of Pathology, Yale University School of Medicine, New Haven Department of Pathology, Bridgeport Hospital, Bridgeport, CT Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
    Am J Surg Pathol 38:189-96. 2014
    ..In conclusion, napsin A is a sensitive and specific biomarker of the clear cell histotype in endometrial carcinomas and accordingly may have diagnostic utility in their histotyping. ..
  8. pmc Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance
    Oluwole Fadare
    Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Hum Pathol 44:1508-15. 2013
    ..These preliminary findings suggest that IMP3 expression may be involved in the pathogenesis of CCC and is worthy of further exploration...
  9. doi request reprint Clinico-pathologic comparison of type II endometrial cancers based on tamoxifen exposure
    Ana I Tergas
    Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, USA
    Gynecol Oncol 127:316-20. 2012
    ..To compare clinico-pathologic variables and protein expression of potential regulatory components in patients who develop type II endometrial cancer with and without antecedent tamoxifen...
  10. pmc Urokinase plasminogen activator system-targeted delivery of nanobins as a novel ovarian cancer therapy
    Yilin Zhang
    Corresponding Author Ernst Lengyel, Department of Obstetrics and Gynecology, University of Chicago, MC 2050, 5841 South Maryland Avenue, Chicago, IL 60637
    Mol Cancer Ther 12:2628-39. 2013
    ..These findings suggest that uPA-targeted nanobins capable of specifically and efficiently delivering payloads to cancer cells could serve as the foundation for a new targeted cancer therapy using protease receptors...
  11. doi request reprint Is GATA3 expression maintained in regional metastases?: a study of paired primary and metastatic urothelial carcinomas
    Lei Zhao
    Department of Pathology, University of Chicago, Chicago, IL Departments of Biostatistics Pathology, University of Washington, Seattle, WA
    Am J Surg Pathol 37:1876-81. 2013
    ..Our findings demonstrate high sensitivity and specificity of the GATA3 diagnostic marker, with not only maintained but increased expression in regional metastases. ..
  12. doi request reprint Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
    Kristin M Nieman
    Department of Obstetrics and Gynecology Section of Gynecologic Oncology, Center for Integrative Science, University of Chicago, Chicago, IL, USA
    Nat Med 17:1498-503. 2011
    ..These data indicate adipocytes provide fatty acids for rapid tumor growth, identifying lipid metabolism and transport as new targets for the treatment of cancers where adipocytes are a major component of the microenvironment...
  13. pmc Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
    Benjamin Boyerinas
    Feinberg School of Medicine, Division Hematology Oncology, Northwestern University, Chicago, IL 60611, USA
    Int J Cancer 130:1787-97. 2012
    ..Our data point at IMP-1 and MDR1 as indicators for response to therapy, and at IMP-1 as a novel therapeutic target for overcoming multidrug resistance of ovarian cancer...
  14. doi request reprint FOXL2 and SOX9 distinguish the lineage of the sex cord-stromal cells in gonadoblastomas
    Rebecca Buell-Gutbrod
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Pediatr Dev Pathol 14:391-5. 2011
    ....
  15. pmc Morphologic and other clinicopathologic features of endometrial clear cell carcinoma: a comprehensive analysis of 50 rigorously classified cases
    Oluwole Fadare
    Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center Nashville, TN, USA Department of Obstetrics and Gynecology, Vanderbilt University Medical Center Nashville, TN, USA
    Am J Cancer Res 3:70-95. 2013
    ....
  16. doi request reprint Sclerosing stromal tumor: an important differential diagnosis of ovarian neoplasms in childhood and adolescence
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    Pediatr Dev Pathol 12:366-70. 2009
    ....
  17. ncbi request reprint Expanding the clinical spectrum of Frasier syndrome
    Katja Gwin
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    Pediatr Dev Pathol 11:122-7. 2008
    ....