Jack M Gwaltney

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint Combined antiviral-antimediator treatment for the common cold
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Infect Dis 186:147-54. 2002
  2. ncbi request reprint Management update of acute bacterial rhinosinusitis and the use of cefdinir
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia Health System, Charlottesville, 22908, USA
    Otolaryngol Head Neck Surg 127:S24-9. 2002
  3. ncbi request reprint Symptom severity patterns in experimental common colds and their usefulness in timing onset of illness in natural colds
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville 22908, USA
    Clin Infect Dis 36:714-23. 2003
  4. ncbi request reprint Acute community-acquired bacterial sinusitis: the value of antimicrobial treatment and the natural history
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Clin Infect Dis 38:227-33. 2004
  5. pmc Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
  6. ncbi request reprint Viral titers in nasal lining fluid compared to viral titers in nasal washes during experimental rhinovirus infection
    J Owen Hendley
    Department of Pediatrics Box 800386, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Clin Virol 30:326-8. 2004
  7. ncbi request reprint Viral respiratory infection therapy: historical perspectives and current trials
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:33S-41S. 2002
  8. ncbi request reprint Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE
    Juan C Zambrano
    Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908 0386, USA
    J Allergy Clin Immunol 111:1008-16. 2003
  9. ncbi request reprint Clinical significance and pathogenesis of viral respiratory infections
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:13S-18S. 2002
  10. ncbi request reprint Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America
    Alan L Bisno
    Department of Medicine, University of Miami School of Medicine and Veterans Affairs Medical Center, Miami, FL 33125, USA
    Clin Infect Dis 35:113-25. 2002

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Combined antiviral-antimediator treatment for the common cold
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Infect Dis 186:147-54. 2002
    ..IFN-alpha2b added to the effectiveness of chlorpheniramine and ibuprofen and was well tolerated...
  2. ncbi request reprint Management update of acute bacterial rhinosinusitis and the use of cefdinir
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia Health System, Charlottesville, 22908, USA
    Otolaryngol Head Neck Surg 127:S24-9. 2002
    ..A 10-day course of treatment with an antimicrobial effective against resistant S pneumoniae and H influenzae is recommended. A clinical trial was reviewed in which cefdinir was effective in treating ABRS...
  3. ncbi request reprint Symptom severity patterns in experimental common colds and their usefulness in timing onset of illness in natural colds
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville 22908, USA
    Clin Infect Dis 36:714-23. 2003
    ..5% of natural colds on day 1 of illness. Histories given by compensated patients in natural cold treatment trials are inaccurate...
  4. ncbi request reprint Acute community-acquired bacterial sinusitis: the value of antimicrobial treatment and the natural history
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Clin Infect Dis 38:227-33. 2004
    ..In 1 controlled trial in which diagnosis was based on duration of unimproved illness, 57% of placebo recipients and 85.5% of treated patients were healthy or had improved by day 10. Additional studies of ACABS are needed...
  5. pmc Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
    ..Results from these studies in experimental rhinoviral infection support continued investigation of intranasal ruprintrivir in the setting of natural HRV infection...
  6. ncbi request reprint Viral titers in nasal lining fluid compared to viral titers in nasal washes during experimental rhinovirus infection
    J Owen Hendley
    Department of Pediatrics Box 800386, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Clin Virol 30:326-8. 2004
    ....
  7. ncbi request reprint Viral respiratory infection therapy: historical perspectives and current trials
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:33S-41S. 2002
    ..This strategy reduces viral shedding in nasal fluid, provides treatment for the period of maximum symptom burden, and may reduce the frequency and severity of the sinus disease that accompanies colds...
  8. ncbi request reprint Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE
    Juan C Zambrano
    Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908 0386, USA
    J Allergy Clin Immunol 111:1008-16. 2003
    ..Although most children and young adults with asthma are atopic, exacerbations of asthma are frequently associated with viral respiratory tract infections, especially those caused by rhinovirus (HRV)...
  9. ncbi request reprint Clinical significance and pathogenesis of viral respiratory infections
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:13S-18S. 2002
    ..Because of the rapidity of symptom onset, early treatment is the key to reducing viral replication and illness. Also, early treatment may reduce the risk of transmission...
  10. ncbi request reprint Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America
    Alan L Bisno
    Department of Medicine, University of Miami School of Medicine and Veterans Affairs Medical Center, Miami, FL 33125, USA
    Clin Infect Dis 35:113-25. 2002
  11. ncbi request reprint Airborne dispersal as a novel transmission route of coagulase-negative staphylococci: interaction between coagulase-negative staphylococci and rhinovirus infection
    Werner E Bischoff
    Section on Infectious Diseases, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1042, USA
    Infect Control Hosp Epidemiol 25:504-11. 2004
    ..To investigate whether rhinovirus infection leads to increased airborne dispersal of coagulase-negative staphylococci (CoNS)...
  12. ncbi request reprint Acute community-acquired bacterial sinusitis: continuing challenges and current management
    Merle A Sande
    Department of Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Clin Infect Dis 39:S151-8. 2004
    ..Antimicrobial agents should be selected on the basis of local resistance patterns, and their spectrum of activity should cover the common bacterial pathogens, including resistant strains...
  13. ncbi request reprint Treatment of naturally acquired common colds with zinc: a structured review
    Thomas J Caruso
    1Stanford University School of Medicine, Stanford, California, USA
    Clin Infect Dis 45:569-74. 2007
    ..Recent reports of potentially permanent anosmia caused by intranasal zinc therapy warrant careful analysis of the therapeutic effects of zinc...
  14. ncbi request reprint Dispersal of Staphylococcus aureus into the air associated with a rhinovirus infection
    Stefano Bassetti
    Section on Infectious Diseases, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Infect Control Hosp Epidemiol 26:196-203. 2005
    ..To determine whether healthy adult nasal carriers of Staphylococcus aureus can disperse S. aureus into the air after rhinovirus infection...
  15. pmc Influenza, Winter Olympiad, 2002
    Adi V Gundlapalli
    University of Utah School of Medicine, Salt Lake City, Utah, USA
    Emerg Infect Dis 12:144-6. 2006
    ..Influenza A/B was diagnosed in 36 of 188 patients, including 13 athletes. Prompt management limited the spread of this outbreak...
  16. ncbi request reprint Treatment of the common cold with echinacea: a structured review
    Thomas J Caruso
    Stanford University School of Medicine, Stanford, CA, USA
    Clin Infect Dis 40:807-10. 2005
    ..Echinacea is a herbal preparation that is frequently used to treat the common cold. Spending on echinacea in the United States has risen to >300 million dollars annually...
  17. ncbi request reprint Rhinosinusitis: establishing definitions for clinical research and patient care
    Eli O Meltzer
    Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    J Allergy Clin Immunol 114:155-212. 2004
  18. ncbi request reprint Rhinosinusitis: Establishing definitions for clinical research and patient care
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
    Otolaryngol Head Neck Surg 131:S1-62. 2004
  19. doi request reprint Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al
    Jack M Gwaltney
    Diagn Microbiol Infect Dis 61:21-2. 2008