Jack M Gwaltney

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi Combined antiviral-antimediator treatment for the common cold
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Infect Dis 186:147-54. 2002
  2. ncbi Management update of acute bacterial rhinosinusitis and the use of cefdinir
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia Health System, Charlottesville, 22908, USA
    Otolaryngol Head Neck Surg 127:S24-9. 2002
  3. ncbi Symptom severity patterns in experimental common colds and their usefulness in timing onset of illness in natural colds
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville 22908, USA
    Clin Infect Dis 36:714-23. 2003
  4. ncbi Acute community-acquired bacterial sinusitis: the value of antimicrobial treatment and the natural history
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Clin Infect Dis 38:227-33. 2004
  5. ncbi Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
  6. ncbi Viral titers in nasal lining fluid compared to viral titers in nasal washes during experimental rhinovirus infection
    J Owen Hendley
    Department of Pediatrics Box 800386, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Clin Virol 30:326-8. 2004
  7. ncbi Viral respiratory infection therapy: historical perspectives and current trials
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:33S-41S. 2002
  8. ncbi Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE
    Juan C Zambrano
    Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908-0386, USA
    J Allergy Clin Immunol 111:1008-16. 2003
  9. ncbi Clinical significance and pathogenesis of viral respiratory infections
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:13S-18S. 2002
  10. ncbi Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America
    Alan L Bisno
    Department of Medicine, University of Miami School of Medicine and Veterans Affairs Medical Center, Miami, FL 33125, USA
    Clin Infect Dis 35:113-25. 2002

Collaborators

Detail Information

Publications19

  1. ncbi Combined antiviral-antimediator treatment for the common cold
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Infect Dis 186:147-54. 2002
    ..IFN-alpha2b added to the effectiveness of chlorpheniramine and ibuprofen and was well tolerated...
  2. ncbi Management update of acute bacterial rhinosinusitis and the use of cefdinir
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia Health System, Charlottesville, 22908, USA
    Otolaryngol Head Neck Surg 127:S24-9. 2002
    ..A 10-day course of treatment with an antimicrobial effective against resistant S pneumoniae and H influenzae is recommended. A clinical trial was reviewed in which cefdinir was effective in treating ABRS...
  3. ncbi Symptom severity patterns in experimental common colds and their usefulness in timing onset of illness in natural colds
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville 22908, USA
    Clin Infect Dis 36:714-23. 2003
    ..5% of natural colds on day 1 of illness. Histories given by compensated patients in natural cold treatment trials are inaccurate...
  4. ncbi Acute community-acquired bacterial sinusitis: the value of antimicrobial treatment and the natural history
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Clin Infect Dis 38:227-33. 2004
    ..In 1 controlled trial in which diagnosis was based on duration of unimproved illness, 57% of placebo recipients and 85.5% of treated patients were healthy or had improved by day 10. Additional studies of ACABS are needed...
  5. ncbi Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
    ..Results from these studies in experimental rhinoviral infection support continued investigation of intranasal ruprintrivir in the setting of natural HRV infection...
  6. ncbi Viral titers in nasal lining fluid compared to viral titers in nasal washes during experimental rhinovirus infection
    J Owen Hendley
    Department of Pediatrics Box 800386, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Clin Virol 30:326-8. 2004
    ....
  7. ncbi Viral respiratory infection therapy: historical perspectives and current trials
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:33S-41S. 2002
    ..This strategy reduces viral shedding in nasal fluid, provides treatment for the period of maximum symptom burden, and may reduce the frequency and severity of the sinus disease that accompanies colds...
  8. ncbi Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE
    Juan C Zambrano
    Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908-0386, USA
    J Allergy Clin Immunol 111:1008-16. 2003
    ....
  9. ncbi Clinical significance and pathogenesis of viral respiratory infections
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Med 112:13S-18S. 2002
    ..Because of the rapidity of symptom onset, early treatment is the key to reducing viral replication and illness. Also, early treatment may reduce the risk of transmission...
  10. ncbi Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America
    Alan L Bisno
    Department of Medicine, University of Miami School of Medicine and Veterans Affairs Medical Center, Miami, FL 33125, USA
    Clin Infect Dis 35:113-25. 2002
  11. ncbi Airborne dispersal as a novel transmission route of coagulase-negative staphylococci: interaction between coagulase-negative staphylococci and rhinovirus infection
    Werner E Bischoff
    Section on Infectious Diseases, Wake Forest University School of Medicine, Winston-Salem, North Carolina. 27157-1042, USA
    Infect Control Hosp Epidemiol 25:504-11. 2004
    ..aureus carriers. Gowns, gloves, and caps had a protective effect, whereas wearing a mask did not further reduce airborne spread...
  12. ncbi Acute community-acquired bacterial sinusitis: continuing challenges and current management
    Merle A Sande
    Department of Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Clin Infect Dis 39:S151-8. 2004
    ..Antimicrobial agents should be selected on the basis of local resistance patterns, and their spectrum of activity should cover the common bacterial pathogens, including resistant strains...
  13. ncbi Treatment of naturally acquired common colds with zinc: a structured review
    Thomas J Caruso
    1Stanford University School of Medicine, Stanford, California, USA
    Clin Infect Dis 45:569-74. 2007
    ..Recent reports of potentially permanent anosmia caused by intranasal zinc therapy warrant careful analysis of the therapeutic effects of zinc...
  14. ncbi Dispersal of Staphylococcus aureus into the air associated with a rhinovirus infection
    Stefano Bassetti
    Section on Infectious Diseases, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
    Infect Control Hosp Epidemiol 26:196-203. 2005
    ..Wearing barrier garb but not a mask decreased dispersal of S. aureus into the air (P < .05). CONCLUSION: Virus-induced dispersal of S. aureus into the air may have an important role in the transmission of S. aureus and other bacteria...
  15. ncbi Influenza, Winter Olympiad, 2002
    Adi V Gundlapalli
    University of Utah School of Medicine, Salt Lake City, Utah, USA
    Emerg Infect Dis 12:144-6. 2006
    ..Influenza A/B was diagnosed in 36 of 188 patients, including 13 athletes. Prompt management limited the spread of this outbreak...
  16. ncbi Treatment of the common cold with echinacea: a structured review
    Thomas J Caruso
    Stanford University School of Medicine, Stanford, CA, USA
    Clin Infect Dis 40:807-10. 2005
    ..The criterion most commonly not met was proof of blinding. CONCLUSIONS: This structured review suggests that the possible therapeutic effectiveness of echinacea in the treatment of colds has not been established...
  17. ncbi Rhinosinusitis: establishing definitions for clinical research and patient care
    Eli O Meltzer
    Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    J Allergy Clin Immunol 114:155-212. 2004
  18. ncbi Rhinosinusitis: Establishing definitions for clinical research and patient care
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
    Otolaryngol Head Neck Surg 131:S1-62. 2004
  19. ncbi Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al
    Jack M Gwaltney
    Diagn Microbiol Infect Dis 61:21-2. 2008