Thomas J Guttuso

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial
    Thomas Guttuso
    Department of Neurology, University of Rochester, Rochester, New York 14642, USA
    Obstet Gynecol 101:337-45. 2003
  2. ncbi request reprint Gabapentin's anti-nausea and anti-emetic effects: a review
    Thomas Guttuso
    Department of Neurology, Obstetrics and Gynecology, University at Buffalo, 3435 Main Street, 97 Farber Hall, Buffalo, NY, 14214 8024, USA
    Exp Brain Res 232:2535-9. 2014
  3. ncbi request reprint Stellate ganglion block for treating hot flashes: a viable treatment option or sham procedure?
    Thomas Guttuso
    University at Buffalo, 3435 Main St, Buffalo, NY 14214, United States Electronic address
    Maturitas 76:221-4. 2013
  4. pmc Nighttime awakenings responding to gabapentin therapy in late premenopausal women: a case series
    Thomas Guttuso
    Department of Neurology, University at Buffalo, Buffalo, NY 14214, USA
    J Clin Sleep Med 8:187-9. 2012
  5. ncbi request reprint Effective and clinically meaningful non-hormonal hot flash therapies
    Thomas Guttuso
    University at Buffalo, Buffalo, NY 14214, United States
    Maturitas 72:6-12. 2012
  6. pmc Review of hot flash diaries
    Thomas Guttuso
    University at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    Maturitas 71:213-6. 2012
  7. ncbi request reprint Responsiveness of life-threatening refractory emesis to gabapentin-scopolamine therapy following posterior fossa surgery. Case report
    Thomas Guttuso
    Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14214, USA
    J Neurosurg 102:547-9. 2005
  8. pmc Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial
    Thomas Guttuso
    University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    Obstet Gynecol 112:109-15. 2008
  9. pmc Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial
    Thomas Guttuso
    University at Buffalo, Buffalo, NY 14214, USA
    Menopause 16:1004-8. 2009
  10. doi request reprint Gabapentin use in hyperemesis gravidarum: a pilot study
    Thomas Guttuso
    Department of Neurology, University at Buffalo, 3435 Main Street, 311 BRB, Buffalo, NY 14214, USA
    Early Hum Dev 86:65-6. 2010

Research Grants

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial
    Thomas Guttuso
    Department of Neurology, University of Rochester, Rochester, New York 14642, USA
    Obstet Gynecol 101:337-45. 2003
    ..To evaluate whether treatment with the anticonvulsant gabapentin may be effective in reducing hot flash frequency and severity...
  2. ncbi request reprint Gabapentin's anti-nausea and anti-emetic effects: a review
    Thomas Guttuso
    Department of Neurology, Obstetrics and Gynecology, University at Buffalo, 3435 Main Street, 97 Farber Hall, Buffalo, NY, 14214 8024, USA
    Exp Brain Res 232:2535-9. 2014
    ..Further research is needed to confirm these initial promising results, which implicate the alpha-2/delta VGCC subunit as a novel therapeutic target in the treatment of several N/V-associated clinical conditions. ..
  3. ncbi request reprint Stellate ganglion block for treating hot flashes: a viable treatment option or sham procedure?
    Thomas Guttuso
    University at Buffalo, 3435 Main St, Buffalo, NY 14214, United States Electronic address
    Maturitas 76:221-4. 2013
    ....
  4. pmc Nighttime awakenings responding to gabapentin therapy in late premenopausal women: a case series
    Thomas Guttuso
    Department of Neurology, University at Buffalo, Buffalo, NY 14214, USA
    J Clin Sleep Med 8:187-9. 2012
    ..Further research is needed to determine if low early follicular phase serum estradiol is associated with nighttime awakenings in premenopausal women not experiencing night sweats...
  5. ncbi request reprint Effective and clinically meaningful non-hormonal hot flash therapies
    Thomas Guttuso
    University at Buffalo, Buffalo, NY 14214, United States
    Maturitas 72:6-12. 2012
    ..Further research is needed with several of these nonhormonal compounds to replicate these findings and to also directly compare their efficacy and tolerability with those of hormone replacement therapy...
  6. pmc Review of hot flash diaries
    Thomas Guttuso
    University at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    Maturitas 71:213-6. 2012
    ..Either diary is acceptable for use in clinical trials...
  7. ncbi request reprint Responsiveness of life-threatening refractory emesis to gabapentin-scopolamine therapy following posterior fossa surgery. Case report
    Thomas Guttuso
    Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14214, USA
    J Neurosurg 102:547-9. 2005
    ....
  8. pmc Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial
    Thomas Guttuso
    University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    Obstet Gynecol 112:109-15. 2008
    ..To investigate whether L-isoleucine was effective in the treatment of hot flushes and whether L-isoleucine, L-valine, or the combination of both amino acids reduced fasting serum homocysteine...
  9. pmc Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial
    Thomas Guttuso
    University at Buffalo, Buffalo, NY 14214, USA
    Menopause 16:1004-8. 2009
    ..Based on a common mechanism of action with gabapentin, we investigated the effects of L-methionine on hot flashes in postmenopausal women...
  10. doi request reprint Gabapentin use in hyperemesis gravidarum: a pilot study
    Thomas Guttuso
    Department of Neurology, University at Buffalo, 3435 Main Street, 311 BRB, Buffalo, NY 14214, USA
    Early Hum Dev 86:65-6. 2010
    ..There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG...
  11. ncbi request reprint Hot flashes refractory to HRT and SSRI therapy but responsive to gabapentin therapy
    Thomas Guttuso
    Departmrnt of Neurology, University of Buffalo School of Medicine, 311 Biomedical Research Building, Buffalo, NY 14214, USA
    J Pain Symptom Manage 27:274-6. 2004
    ..She markedly responded to gabapentin therapy. Gabapentin, SSRIs, and estrogen may act at different cellular targets in the treatment of hot flashes...
  12. ncbi request reprint Effect of gabapentin on nausea induced by chemotherapy in patients with breast cancer
    Thomas Guttuso
    Department of Neurology, Box 673, University of Rochester, Rochester, NY 14642, USA
    Lancet 361:1703-5. 2003
    ..This preliminary evidence shows that gabapentin might have a role in treatment of chemotherapy-induced nausea...
  13. doi request reprint Effects of gabapentin on sleep in menopausal women with hot flashes as measured by a Pittsburgh Sleep Quality Index factor scoring model
    Michael E Yurcheshen
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Strong Sleep Disorders Center, Rochester, New York 14618, USA
    J Womens Health (Larchmt) 18:1355-60. 2009
    ..The aim of this research was to analyze gabapentin's effect on Pittsburgh Sleep Quality Index (PSQI) scores in menopausal women...
  14. ncbi request reprint Pilot study using gabapentin for tamoxifen-induced hot flashes in women with breast cancer
    Kishan J Pandya
    James P Wilmot Cancer Center, University of Rochester, Rochester, NY 14642 USA
    Breast Cancer Res Treat 83:87-9. 2004
    ..Two additional patients did not provide complete data. Gabapentin is a promising new agent in the treatment of tamoxifen induced hot flashes, and should be studied further...

Research Grants1

  1. Effects of Amino Acid Therapy on Hot Flashes in Postmenopausal Women
    Thomas Guttuso; Fiscal Year: 2007
    ..The applicant will also attend two didactic training seminars in complementary & alternative medicine at The Osher Institute at Harvard Medical School and at the Duke Center for Integrative Medicine. ..