Research TopicsGenomes and Genes | ASA BIRGITTA GUSTAFSSONSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult miceChengqun Huang
San Diego State University, BioScience Center and Department of Biology, CA, USA
Circulation 121:675-83. 2010..To date, very little is known about the mechanism of this late-onset cardiotoxicity...
Mitochondria and mitophagy: the yin and yang of cell death controlDieter A Kubli
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA
Circ Res 111:1208-21. 2012..Herein, we discuss the importance of mitochondria and mitophagy in cardiovascular health and disease and provide a review of our current understanding of how these processes are regulated...
Bnip3 as a dual regulator of mitochondrial turnover and cell death in the myocardiumAsa B Gustafsson
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive MC 0758, La Jolla, CA 92093 0758, USA
Pediatr Cardiol 32:267-74. 2011..Recent studies suggest that Bnip3 might have a dual function in the myocardium, where it regulates both mitochondrial turnover via autophagy and cell death and that these are two separate processes activated by Bnip3...
Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytesYoungil Lee
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093 0758, USA
Am J Physiol Heart Circ Physiol 301:H1924-31. 2011..Thus our data suggest that induction of autophagy in response to Bnip3 is a protective response activated by the cell that involves Drp1-mediated mitochondrial fission and recruitment of Parkin...
Research Grants
- Mcl-1 as an essential regulator of cardiac mitochondrial functionASA BIRGITTA GUSTAFSSON; Fiscal Year: 2010..This project will provide important new insights into mitochondrial function in cardiac myocytes and how mitochondrial dysfunction contributes to development of cardiovascular disease. (End of Abstract) ..
- Role of Bnip3 in Myocardial Ischemia/ReperfusionASA BIRGITTA GUSTAFSSON; Fiscal Year: 2010..Further understanding of how BnipS functions in the heart has the potential to identify new therapeutic targets to treat or prevent heart disease. ..
- Role of Bnip3 in Myocardial Ischemia/ReperfusionASA BIRGITTA GUSTAFSSON; Fiscal Year: 2009..Further understanding of how BnipS functions in the heart has the potential to identify new therapeutic targets to treat or prevent heart disease. ..
