David Gur

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Breast cancer screening in a multimodality environment-the need for a simple summary measure of marginal value
    David Gur
    Department of Radiology, Imaging Research, University of Pittsburgh, 3362 Fifth Ave, Pittsburgh, PA 15213 3180 Electronic address
    Acad Radiol 21:325-8. 2014
  2. pmc Dose reduction in digital breast tomosynthesis (DBT) screening using synthetically reconstructed projection images: an observer performance study
    David Gur
    University of Pittsburgh, Department of Radiology, Radiology Imaging Research, Pittsburgh, PA 15213, USA
    Acad Radiol 19:166-71. 2012
  3. pmc Development of a clinical decision model for thyroid nodules
    Alexander Stojadinovic
    Department of Surgery, Division of Surgical Oncology, Walter Reed Army Medical Center, Washington, DC, USA
    BMC Surg 9:12. 2009
  4. ncbi request reprint Changes in breast cancer detection and mammography recall rates after the introduction of a computer-aided detection system
    David Gur
    Department of Radiology, University of Pittsburgh, Magee Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Natl Cancer Inst 96:185-90. 2004
  5. ncbi request reprint Variability in observer performance studies experimental observations
    David Gur
    Department of Radiology, School of Medicine, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 12:1527-33. 2005
  6. pmc Comparing areas under receiver operating characteristic curves: potential impact of the "Last" experimentally measured operating point
    David Gur
    Department of Radiology, Graduate School of Public Health, University of Pittsburgh, Imaging Research, FARP Building, 3362 Fifth Ave, Pittsburgh, PA 15213, USA
    Radiology 247:12-5. 2008
  7. ncbi request reprint Computer-aided detection performance in mammographic examination of masses: assessment
    David Gur
    Department of Radiology and Magee Womens Hospital, University of Pittsburgh, 300 Halket St, Suite 4200, Pittsburgh, PA 15213 3180, USA
    Radiology 233:418-23. 2004
  8. ncbi request reprint Tomosynthesis: potential clinical role in breast imaging
    David Gur
    Department of Radiology, Imaging Research, University of Pittsburgh, 3362 Fifth Ave, FARP Bldg, Rm 223, Pittsburgh, PA 15213 3180, USA
    AJR Am J Roentgenol 189:614-5. 2007
  9. ncbi request reprint "Binary" and "non-binary" detection tasks: are current performance measures optimal?
    David Gur
    Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Acad Radiol 14:871-6. 2007
  10. pmc The prevalence effect in a laboratory environment: Changing the confidence ratings
    David Gur
    Department of Radiology, Imaging Research, Suite 4200 Magee Womens Hospital, 300 Halket Street, School of Medicine, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 14:49-53. 2007

Detail Information

Publications96

  1. ncbi request reprint Breast cancer screening in a multimodality environment-the need for a simple summary measure of marginal value
    David Gur
    Department of Radiology, Imaging Research, University of Pittsburgh, 3362 Fifth Ave, Pittsburgh, PA 15213 3180 Electronic address
    Acad Radiol 21:325-8. 2014
    ....
  2. pmc Dose reduction in digital breast tomosynthesis (DBT) screening using synthetically reconstructed projection images: an observer performance study
    David Gur
    University of Pittsburgh, Department of Radiology, Radiology Imaging Research, Pittsburgh, PA 15213, USA
    Acad Radiol 19:166-71. 2012
    ....
  3. pmc Development of a clinical decision model for thyroid nodules
    Alexander Stojadinovic
    Department of Surgery, Division of Surgical Oncology, Walter Reed Army Medical Center, Washington, DC, USA
    BMC Surg 9:12. 2009
    ..Clinical models predictive of malignancy risk are needed to support treatment decisions in patients with thyroid nodules in order to reduce morbidity associated with unnecessary diagnostic surgery...
  4. ncbi request reprint Changes in breast cancer detection and mammography recall rates after the introduction of a computer-aided detection system
    David Gur
    Department of Radiology, University of Pittsburgh, Magee Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Natl Cancer Inst 96:185-90. 2004
    ..We assessed changes in mammography recall and cancer detection rates after the introduction of a computer-aided detection system into a clinical radiology practice in an academic setting...
  5. ncbi request reprint Variability in observer performance studies experimental observations
    David Gur
    Department of Radiology, School of Medicine, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 12:1527-33. 2005
    ..The aim of the study is to assess variance components in observer performance studies and the possible impact on study results and conclusions...
  6. pmc Comparing areas under receiver operating characteristic curves: potential impact of the "Last" experimentally measured operating point
    David Gur
    Department of Radiology, Graduate School of Public Health, University of Pittsburgh, Imaging Research, FARP Building, 3362 Fifth Ave, Pittsburgh, PA 15213, USA
    Radiology 247:12-5. 2008
    ..This is followed by recommendations that should help prevent misinterpretation of results...
  7. ncbi request reprint Computer-aided detection performance in mammographic examination of masses: assessment
    David Gur
    Department of Radiology and Magee Womens Hospital, University of Pittsburgh, 300 Halket St, Suite 4200, Pittsburgh, PA 15213 3180, USA
    Radiology 233:418-23. 2004
    ..To compare performance of two computer-aided detection (CAD) systems and an in-house scheme applied to five groups of sequentially acquired screening mammograms...
  8. ncbi request reprint Tomosynthesis: potential clinical role in breast imaging
    David Gur
    Department of Radiology, Imaging Research, University of Pittsburgh, 3362 Fifth Ave, FARP Bldg, Rm 223, Pittsburgh, PA 15213 3180, USA
    AJR Am J Roentgenol 189:614-5. 2007
  9. ncbi request reprint "Binary" and "non-binary" detection tasks: are current performance measures optimal?
    David Gur
    Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Acad Radiol 14:871-6. 2007
    ....
  10. pmc The prevalence effect in a laboratory environment: Changing the confidence ratings
    David Gur
    Department of Radiology, Imaging Research, Suite 4200 Magee Womens Hospital, 300 Halket Street, School of Medicine, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 14:49-53. 2007
    ..We sought to assess whether or not prevalence levels affected the confidence ratings of readers during the interpretation of cases in a laboratory receiver operating characteristic-type observer performance study...
  11. ncbi request reprint CAD in screening mammography
    David Gur
    Department of Radiology, Imaging Research, Ste 4200, University of Pittsburgh, Magee Womens Hospital, 300 Halket St, Pittsburgh, PA 15213 3180, USA
    AJR Am J Roentgenol 187:1474. 2006
    ..Our purpose is to reflect on and interleave two articles in this issue of the AJR that highlight the difficulty in assessing the actual benefit of using CAD from either retrospective or prospective studies...
  12. ncbi request reprint Trends in recall, biopsy, and positive biopsy rates for screening mammography in an academic practice
    David Gur
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital of the University of Pittsburgh Medical Center, 300 Halket Street, Imaging Research, Suite 4200, Pittsburgh, PA 15213 3180, USA
    Radiology 235:396-401. 2005
    ....
  13. ncbi request reprint Reader variance in ROC studies--generalizability to reader population at high and low performance levels
    David Gur
    Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Acad Radiol 13:1004-10. 2006
    ..To investigate the variability between discriminative performances of readers as a function of average performance levels during receiver operating characteristic (ROC) studies...
  14. ncbi request reprint The effect of image display size on observer performance an assessment of variance components
    David Gur
    Department of Radiology, School of Medicine, Imaging Research, Suite 4200 Magee Womens Hospital, 300 Halket Street, Pittsburgh, PA 15261, USA
    Acad Radiol 13:409-13. 2006
    ..Our goal was to investigate the effect of the displayed image size on variance components during the performance of an observer performance study to detect masses on abdominal computed tomography (CT) examinations...
  15. pmc The "laboratory" effect: comparing radiologists' performance and variability during prospective clinical and laboratory mammography interpretations
    David Gur
    Department of Radiology, University of Pittsburgh School of Medicine, 3362 Fifth Ave, Pittsburgh, Pa 15213 31803, USA
    Radiology 249:47-53. 2008
    ..To compare radiologists' performance during interpretation of screening mammograms in the clinic with their performance when reading the same mammograms in a retrospective laboratory study...
  16. pmc Agreement of the order of overall performance levels under different reading paradigms
    David Gur
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 15:1567-73. 2008
    ..To investigate consistency of the orders of performance levels when interpreting mammograms under three different reading paradigms...
  17. pmc Is an ROC-type response truly always better than a binary response in observer performance studies?
    David Gur
    University of Pittsburgh, Department of Radiology, Radiology Imaging Research, Pittsburgh, PA 15213, USA
    Acad Radiol 17:639-45. 2010
    ....
  18. doi request reprint Retrospective analyses of pivotal prospective studies with population segmentation: statistically based inferences and clinical relevance
    David Gur
    University of Pittsburgh, School of Medicine, Department of Radiology, Imaging Research, Pittsburgh, PA 15213, USA
    Acad Radiol 15:1458-62. 2008
    ....
  19. pmc Binary and multi-category ratings in a laboratory observer performance study: a comparison
    David Gur
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 35:4404-9. 2008
    ....
  20. pmc Performance assessments of diagnostic systems under the FROC paradigm: experimental, analytical, and results interpretation issues
    David Gur
    Department of Radiology, School of Medicine, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, PA 15261 3180, USA
    Acad Radiol 15:1312-5. 2008
    ..These issues are rarely discussed and are the focus of this work...
  21. doi request reprint Localized detection and classification of abnormalities on FFDM and tomosynthesis examinations rated under an FROC paradigm
    David Gur
    Department of Radiology, University of Pittsburgh, Radiology Imaging Research, PA 15213 3180, USA
    AJR Am J Roentgenol 196:737-41. 2011
    ....
  22. doi request reprint Digital breast tomosynthesis: observer performance study
    David Gur
    Radiology Imaging Research, Department of Radiology, University of Pittsburgh, 3362 Fifth Ave, Rm 223 FARP Bldg, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 193:586-91. 2009
    ..The purpose of this study was to compare in a retrospective observer study the diagnostic performance of full-field digital mammography (FFDM) with that of digital breast tomosynthesis...
  23. pmc A multisite telemammography system for remote management of screening mammography: an assessment of technical, operational, and clinical issues
    Joseph K Leader
    Imaging Research Division, Department of Radiology, University of Pittsburgh, 300 Halket Street, Suite 4200, Pittsburgh, PA, 15213, USA
    J Digit Imaging 19:216-25. 2006
    ..One goal is to reduce the number of women who would physically need to return to the clinic for additional imaging procedures (termed "recall") to supplement "routine" imaging of screening mammography...
  24. ncbi request reprint A method to improve visual similarity of breast masses for an interactive computer-aided diagnosis environment
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 33:111-7. 2006
    ....
  25. ncbi request reprint Multiview-based computer-aided detection scheme for breast masses
    Bin Zheng
    Department of Radiology, University of Pittsburgh, 300 Halket Street, Suite 4200, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 33:3135-43. 2006
    ..7% (from 539 to 411). The study demonstrated that the new multiview-based CAD scheme could substantially increase the number of masses being cued on two ipsilateral views while reducing the case-based false-positive detection rate...
  26. ncbi request reprint Recall and detection rates in screening mammography
    David Gur
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital, Pittsburgh, Pennsylvania 15213, USA
    Cancer 100:1590-4. 2004
    ..The authors investigated the correlation between recall and detection rates in a group of 10 radiologists who had read a high volume of screening mammograms in an academic institution...
  27. pmc Pulmonary lobe segmentation in CT examinations using implicit surface fitting
    Jiantao Pu
    Imaging Research Division, Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    IEEE Trans Med Imaging 28:1986-96. 2009
    ..5 mm. The advantages of this scheme are its full automation, relative insensitivity to fissure completeness, and ease of implementation...
  28. doi request reprint Digital breast tomosynthesis: a pilot observer study
    Walter F Good
    Department of Radiology, Imaging Research, University of Pittsburgh, F A R P Bldg, 3362 Fifth Ave, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 190:865-9. 2008
    ..The objective of our study was to assess ergonomic and diagnostic performance-related issues associated with the interpretation of digital breast tomosynthesis-generated examinations...
  29. pmc Detection of breast abnormalities using a prototype resonance electrical impedance spectroscopy system: a preliminary study
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 35:3041-8. 2008
    ....
  30. pmc Interactive computer-aided diagnosis of breast masses: computerized selection of visually similar image sets from a reference library
    Bin Zheng
    Department of Radiology, Imaging Research Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Acad Radiol 14:917-27. 2007
    ..The objective of this study is to develop and test a new ICAD scheme that aims improve visual similarity of ICAD-selected reference regions...
  31. ncbi request reprint "Memory effect" in observer performance studies of mammograms
    Lara A Hardesty
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA 15213 3180
    Acad Radiol 12:286-90. 2005
    ..To evaluate breast radiologists' recognition of mammograms showing cancers that they correctly detected or "missed" during clinical interpretations...
  32. doi request reprint Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison
    M Lee Spangler
    Department of Radiology, University of Pittsburgh Medical Center, 3950 Presby South Towers, 200 Lothrop St, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 196:320-4. 2011
    ..The purpose of this article is to compare the ability of digital breast tomosynthesis and full field digital mammography (FFDM) to detect and characterize calcifications...
  33. pmc An ellipse-fitting based method for efficient registration of breast masses on two mammographic views
    Jiantao Pu
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 35:487-94. 2008
    ..The results demonstrate the feasibility of the proposed method to automatically identify masses depicted on CC and MLO views, which may improve future development of multiview based CAD schemes...
  34. ncbi request reprint Head-mounted versus remote eye tracking of radiologists searching for breast cancer: a comparison
    Claudia Mello-Thoms
    University of Pittsburgh, Department of Radiology, Pittsburgh, PA 15213, USA
    Acad Radiol 13:203-9. 2006
    ..We compared performance and visual search parameters of radiologists detecting masses on mammograms by using both a head-mounted (HDMT) and a remote (REM) eye tracker...
  35. pmc Computerized identification of airway wall in CT examinations using a 3D active surface evolution approach
    Suicheng Gu
    Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Med Image Anal 17:283-96. 2013
    ..For a clinical chest CT examination, it took around 4 min for this scheme to identify the inner and outer airway walls on a modern PC...
  36. pmc Optimal threshold in CT quantification of emphysema
    Zhimin Wang
    Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Eur Radiol 23:975-84. 2013
    ..To determine the optimal threshold by quantitatively assessing the extent of emphysema at the level of the entire lung and at the level of individual lobes using a large, diverse dataset of computed tomography (CT) examinations...
  37. pmc Three-dimensional airway tree architecture and pulmonary function
    Jiantao Pu
    University of Pittsburgh, Department of Radiology, PA 15213, USA
    Acad Radiol 19:1395-401. 2012
    ..The objective of this study was to investigate the correlation between airway tree architecture, as depicted on computed tomography, and pulmonary function...
  38. pmc Digital breast tomosynthesis versus supplemental diagnostic mammographic views for evaluation of noncalcified breast lesions
    Margarita L Zuley
    Department of Radiology, Magee Womens Hospital, University of Pittsburgh Medical Center, 300 Halket St, Pittsburgh, PA 15213, USA
    Radiology 266:89-95. 2013
    ..To compare the diagnostic performance of breast tomosynthesis versus supplemental mammography views in classification of masses, distortions, and asymmetries...
  39. pmc The relationship between pulmonary emphysema and kidney function in smokers
    Divay Chandra
    Emphysema COPD Research Center, University of Pittsburgh, Pittsburgh, PA, USA
    Chest 142:655-62. 2012
    ..We hypothesized that kidney dysfunction would associate with emphysema rather than with airflow obstruction measured by the FEV₁...
  40. ncbi request reprint Integrated density of a lesion: a quantitative, mammographically derived, invariable measure
    Yuan Hsiang Chang
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 30:1805-11. 2003
    ..There is a high degree of correlation between ID-based measures obtained from different views of the same mass. ID-based measures showed a higher degree of invariance than mass diameter or effective size...
  41. ncbi request reprint Computerized estimation of the lung volume removed during lung volume reduction surgery
    Sebastien Gilbert
    Department of Surgery, University of Pittsburgh, Imaging Research Division, 300 Halket Street, Suite 4200, Pittsburgh, PA 15213, USA
    Acad Radiol 13:1379-86. 2006
    ..This study was designed to develop an automated method for estimating lung volume removed during lung volume reduction surgery (LVRS) using computed tomography (CT)...
  42. pmc Radiographic emphysema predicts low bone mineral density in a tobacco-exposed cohort
    JESSICA BON
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Respir Crit Care Med 183:885-90. 2011
    ..Whereas emphysema has been independently associated with vascular disease and other comorbidities, its association with BMD has not been well studied...
  43. ncbi request reprint Computer-aided detection in mammography: an assessment of performance on current and prior images
    Bin Zheng
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital, PA 15213, USA
    Acad Radiol 9:1245-50. 2002
    ....
  44. pmc Matching breast masses depicted on different views a comparison of three methods
    Bin Zheng
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, PA 15213, USA
    Acad Radiol 16:1338-47. 2009
    ..The purpose of this study was to compare three methods aimed at matching CAD-cued mass regions depicted on two views and the associated impact on CAD performance...
  45. pmc On comparing methods for discriminating between actually negative and actually positive subjects with FROC type data
    Tao Song
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Med Phys 35:1547-58. 2008
    ..We also investigate the properties of the statistical procedures in a simulation study...
  46. ncbi request reprint Detection and classification performance levels of mammographic masses under different computer-aided detection cueing environments
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Magee Womens Hospital, Pittsburgh, PA, USA
    Acad Radiol 11:398-406. 2004
    ..The authors evaluated the impact of different computer-aided detection (CAD) cueing conditions on radiologists' performance levels in detecting and classifying masses depicted on mammograms...
  47. pmc A Computational geometry approach to automated pulmonary fissure segmentation in CT examinations
    Jiantao Pu
    Imaging Research Division, Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    IEEE Trans Med Imaging 28:710-9. 2009
    ..48 +/-0.92 to 2.04 +/-3.88 mm. The discrepancy of fissure detection results between the automated scheme and either radiologist is smaller in this dataset than the interreader variability...
  48. doi request reprint Time to diagnosis and performance levels during repeat interpretations of digital breast tomosynthesis: preliminary observations
    Margarita L Zuley
    Department of Radiology, Magee Womens Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Acad Radiol 17:450-5. 2010
    ..To compare time to interpretation and diagnostic performance levels during repeat readings of full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) in a retrospective study...
  49. pmc An automated CT based lung nodule detection scheme using geometric analysis of signed distance field
    Jiantao Pu
    Imaging Research Center, Department of Radiology University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 35:3453-61. 2008
    ..In addition to potentially being a stand alone approach, the signed distance field based method can be easily implemented as an initial filtering step in other computer-aided detection schemes...
  50. pmc Bilateral mammographic density asymmetry and breast cancer risk: a preliminary assessment
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Magee Womens Hospital, 3362 Fifth Ave, Pittsburgh, PA 15213, USA
    Eur J Radiol 81:3222-8. 2012
    ....
  51. ncbi request reprint Computer-aided detection schemes: the effect of limiting the number of cued regions in each case
    Bin Zheng
    Department of Radiology, Imaging Research, Magee Women s Hospital, University of Pittsburgh, 300 Halket St, Ste 4200, Pittsburgh, PA 15213 3180, USA
    AJR Am J Roentgenol 182:579-83. 2004
    ..We assessed performance changes of a mammographic computer-aided detection scheme when we restricted the maximum number of regions that could be identified (cued) as showing positive findings in each case...
  52. ncbi request reprint Performance change of mammographic CAD schemes optimized with most-recent and prior image databases
    Bin Zheng
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital, 300 Halket St, Suite 4200, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 10:283-8. 2003
    ....
  53. ncbi request reprint Is maximum positive predictive value a good indicator of an optimal screening mammography practice?
    Lara A Hardesty
    Department of Radiology, University of Pittsburgh Medical Center, Magee Women s Hospital, 300 Halket St, Ste 4200, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 184:1505-7. 2005
    ..We show how the relationship between sensitivity and recall rate may affect the operating point at which optimal (maximum) PPV1 occurs...
  54. ncbi request reprint A comparison of two data analyses from two observer performance studies using Jackknife ROC and JAFROC
    Bin Zheng
    Department of Radiology, University of Pittsburgh, 300 Halket Street, Suite 4200, Pittsburgh, Pennsylvania 15213 3180, USA
    Med Phys 32:1031-4. 2005
    ..In the second study, LABMRMC showed no significant differences for any paired data sets and JAFROC showed a significant difference for one pair. In 15 of 16 pairs, p values computed by JAFROC were lower than those computed by LABMRMC...
  55. ncbi request reprint Performance and reproducibility of a computerized mass detection scheme for digitized mammography using rotated and resampled images: an assessment
    Bin Zheng
    Department of Radiology, University of Pittsburgh, 300 Halket St, Ste 4200, Pittsburgh, PA 15213 3180, USA
    AJR Am J Roentgenol 185:194-8. 2005
    ....
  56. ncbi request reprint A permutation test for comparing ROC curves in multireader studies a multi-reader ROC, permutation test
    Andriy I Bandos
    Department of Biostatistics, Graduate School of Public Health, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 13:414-20. 2006
    ..The aim of the study is to develop a permutation test to compare receiver operating characteristic (ROC) curves of two diagnostic modalities in a multireader paired design...
  57. pmc Assessment of lung volume collapsibility in chronic obstructive lung disease patients using CT
    Shinjini Kundu
    Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Eur Radiol 23:1564-72. 2013
    ....
  58. ncbi request reprint Observer performance studies: detection of single versus multiple abnormalities of the chest
    Carl R Fuhrman
    Department of Radiology, University of Pittsburgh, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
    AJR Am J Roentgenol 179:1551-3. 2002
    ..In the first method, the abnormality in question, rib fracture, was one of five investigated, and it was the only one of interest in the second...
  59. pmc Evaluation of lung MDCT nodule annotation across radiologists and methods
    Charles R Meyer
    Department of Radiology, School of Medicine, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48109 2200, USA
    Acad Radiol 13:1254-65. 2006
    ..Thus assessing the source of variability in defining the spatial location of lung nodules by expert radiologists using different software tools as an alternative form of truth is necessary...
  60. ncbi request reprint A method to test the reproducibility and to improve performance of computer-aided detection schemes for digitized mammograms
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 3180, USA
    Med Phys 31:2964-72. 2004
    ....
  61. ncbi request reprint Digital breast tomosynthesis in the diagnostic environment: A subjective side-by-side review
    Christiane M Hakim
    Department of Radiology, Magee Womens Hospital, University of Pittsburgh, PA, USA
    AJR Am J Roentgenol 195:W172-6. 2010
    ..The purpose of our study was to subjectively compare additional mammographic views to digital breast tomosynthesis (DBT) in the characterizing of known masses, architectural distortions, or asymmetries...
  62. ncbi request reprint Prevalence effect in a laboratory environment
    David Gur
    Department of Radiology, Imaging Research, Suite 4200, University of Pittsburgh, 300 Halket St, Pittsburgh, PA 15213 3180, USA
    Radiology 228:10-4. 2003
    ..To measure observer performance at various levels of prevalence...
  63. ncbi request reprint Screening mammography: do women prefer a higher recall rate given the possibility of earlier detection of cancer?
    Marie A Ganott
    Department of Radiology, University of Pittsburgh Medical Center, Imaging Research, Suite 4200, PA 15213, USA
    Radiology 238:793-800. 2006
    ..To prospectively survey women undergoing screening mammography to assess their attitudes toward and preference for the level of recall rates given the possibility that an increase in recall rates may result in earlier detection of cancer...
  64. pmc A preliminary evaluation of multi-probe resonance-frequency electrical impedance based measurements of the breast
    Bin Zheng
    Department of Radiology, University of Pittsburgh, PA 15213, USA
    Acad Radiol 18:220-9. 2011
    ..The aim of this study was to preliminarily assess the performance of a new, resonance-frequency electrical impedance spectroscopy (REIS) system in identifying young women who were recommended to undergo breast biopsy following imaging...
  65. ncbi request reprint Optimal reference mammography: a comparison of mammograms obtained 1 and 2 years before the present examination
    Jules H Sumkin
    Department of Radiology, Imaging Research, Ste 4200, University of Pittsburgh and Magee Womens Hospital, 300 Halket St, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 180:343-6. 2003
    ..We assessed and compared the benefit of using images acquired 1 year or 2 years previously during mammography interpretations...
  66. pmc Computer-aided detection; the effect of training databases on detection of subtle breast masses
    Bin Zheng
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Room 128, Pittsburgh, PA 15213, USA
    Acad Radiol 17:1401-8. 2010
    ..The aim of this study was to investigate the effect of training database case selection on CAD performance in detecting low-conspicuity breast masses...
  67. pmc A GMM-based breast cancer risk stratification using a resonance-frequency electrical impedance spectroscopy
    Dror Lederman
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 38:1649-59. 2011
    ....
  68. pmc Computerized assessment of pulmonary fissure integrity using high resolution CT
    Jiantao Pu
    Department of Radiology, Imaging Research Center, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 37:4661-72. 2010
    ..Knowledge of pulmonary interlobar fissure integrity is of interest in a number of clinical and investigational applications. The authors developed and tested a high resolution CT based automated computerized scheme for this purpose...
  69. ncbi request reprint Size and morphology of the trachea before and after lung volume reduction surgery
    Joseph K Leader
    Department of Radiology, Imaging Research Division, University of Pittsburgh, 300 Halket St, Ste 4200, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 183:315-21. 2004
    ..The purpose of this investigation was to determine the effect of lung volume reduction surgery on measured tracheal features...
  70. doi request reprint Improving breast cancer risk stratification using resonance-frequency electrical impedance spectroscopy through fusion of multiple classifiers
    Dror Lederman
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, PA 15213, USA
    Ann Biomed Eng 39:931-45. 2011
    ..The study demonstrated that REIS examinations provide relevant information for developing breast cancer risk stratification tools and that using fusion of several not-fully-correlated classifiers can improve classification performance...
  71. ncbi request reprint Prescreening mammography by technologists: a preliminary assessment
    Jules H Sumkin
    Department of Radiology, University of Pittsburgh and Magee Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, USA
    AJR Am J Roentgenol 180:253-6. 2003
    ..We assessed the ability of technologists to accurately classify screening mammograms as either showing negative findings or requiring follow-up...
  72. pmc A differential geometric approach to automated segmentation of human airway tree
    Jiantao Pu
    Imaging Research Division, Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    IEEE Trans Med Imaging 30:266-78. 2011
    ....
  73. pmc The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease
    Jessica M Bon
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 4:e6865. 2009
    ..A cross-sectional study was performed to examine the association of serum biomarkers with radiographic airway and parenchymal phenotypes of COPD...
  74. ncbi request reprint Lung cancer screening: simulations of effects of imperfect detection on temporal dynamics
    Brian E Chapman
    Department of Radiology, University of Pittsburgh, Imaging Research, Suite 4200, 300 Halket St, Pittsburgh, PA 15213, USA
    Radiology 234:582-90. 2005
    ..To use a mathematic model to demonstrate effects of imperfect detection on temporal dynamics of radiologic lung cancer screening...
  75. ncbi request reprint Automated detection and quantitative assessment of pulmonary airways depicted on CT images
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 34:2844-52. 2007
    ....
  76. ncbi request reprint Computerized assessment of tissue composition on digitized mammograms
    Yuan Hsiang Chang
    Department of Radiology, Imaging Research, University of Pittsburgh, PA 15213, USA
    Acad Radiol 9:899-905. 2002
    ..The authors developed a computerized method for the quantitative assessment of breast tissue composition on digitized mammograms...
  77. ncbi request reprint A conditional nonparametric test for comparing two areas under the ROC curves from a paired design
    Andriy I Bandos
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA anb61 pitt edu
    Acad Radiol 12:291-7. 2005
    ..To develop a conditional nonparametric procedure for comparing two correlated areas under receiver operating characteristic (ROC) curves (AUC)...
  78. ncbi request reprint Incorporating utility-weights when comparing two diagnostic systems: a preliminary assessment
    Andriy I Bandos
    Department of Biostatistics, Graduate School of Public Health, Department of Radiology, Imaging, Suite 4200, Magee Women s Hospital, University of Pittsburgh, Pittsburgh, PA 15216, USA
    Acad Radiol 12:1293-300. 2005
    ..We sought to develop a new index that incorporates utility-weights when assessing the overall performance of a diagnostic system and to provide a statistical test for comparing two indices in a paired study design...
  79. ncbi request reprint Automated lung segmentation in X-ray computed tomography: development and evaluation of a heuristic threshold-based scheme
    Joseph K Leader
    Department of Radiology, University of Pittsburgh, Imaging Research Division, 300 Halket St, Suite 4200, Pittsburgh, PA 15213, USA
    Acad Radiol 10:1224-36. 2003
    ..To develop and evaluate a reliable, fully-automated lung segmentation scheme for application in X-ray computed tomography...
  80. pmc Area under the free-response ROC curve (FROC) and a related summary index
    Andriy I Bandos
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Biometrics 65:247-56. 2009
    ..We provide an example with a dataset sampled from a diagnostic imaging study and conduct simulations that demonstrate the appropriateness of the developed procedure for the considered sample sizes and ranges of parameters...
  81. ncbi request reprint From the laboratory to the clinic: the "prevalence effect"
    David Gur
    Department of Imaging Research, Suite 4200, 300 Halket Street, University of Pittsburgh, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 10:1324-6. 2003
  82. ncbi request reprint On the repeated use of databases for testing incremental improvement of computer-aided detection schemes
    David Gur
    Department of Radiology, Imaging Research, Suite 4200, University of Pittsburgh, 300 Halket St, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 11:103-5. 2004
  83. ncbi request reprint Electrical impedance scanning for the early detection of breast cancer in young women: preliminary results of a multicenter prospective clinical trial
    Alexander Stojadinovic
    Department of Surgery, Walter Reed Army Medical Center, 6900 Georgia Ave NW, Washington, DC 20307, USA
    J Clin Oncol 23:2703-15. 2005
    ..To evaluate the feasibility and patient satisfaction with electrical impedance scanning (EIS) for early detection of breast cancer in young women...
  84. ncbi request reprint Objectively measuring and comparing performance levels of diagnostic imaging systems and practices
    David Gur
    Acad Radiol 14:641-2. 2007
  85. ncbi request reprint Technology and practice assessment: in search of a "desirable" statement
    David Gur
    Radiology 234:659-60. 2005
  86. ncbi request reprint Computer-aided detection with screening mammography: improving performance or simply shifting the operating point?
    Jules H Sumkin
    Radiology 239:916-7; author reply 917-8. 2006
  87. doi request reprint Imaging technology and practice assessment studies: importance of the baseline or reference performance level
    David Gur
    Radiology 247:8-11. 2008
  88. ncbi request reprint Digital mammography: do we need to convert now?
    David Gur
    Radiology 245:10-1. 2007
  89. ncbi request reprint Electrical impedance scanning as a new breast cancer risk stratification tool for young women
    Alexander Stojadinovic
    Department of Surgery, Walter Reed Army Medical Center, Washington, DC, USA
    J Surg Oncol 97:112-20. 2008
    ..The T-Scan(tm2000 (ED is designed to use EIS to identify women ages 30-39 with elevated risk of breast cancer (i.e., T-Scan+ women)...
  90. pmc Selection of a rating scale in receiver operating characteristic studies: some remaining issues
    Howard E Rockette
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Acad Radiol 15:245-8. 2008
    ....
  91. ncbi request reprint Re: Computer-aided detection of breast cancer: has promise outstripped performance?
    David Gur
    J Natl Cancer Inst 96:717-8; author reply 718. 2004
  92. ncbi request reprint Assessment methodologies and statistical issues for computer-aided diagnosis of lung nodules in computed tomography: contemporary research topics relevant to the lung image database consortium
    Lori E Dodd
    Biometrics Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Blvd, MSC 7434, Bethesda, MD 20892, USA
    Acad Radiol 11:462-75. 2004
    ..We review methods for performance assessment and discuss issues of defining "truth" as well as the complications that arise when truth information is not available. We also discuss issues about sizing and populating a database...
  93. ncbi request reprint Computer-aided screening mammography
    David Gur
    N Engl J Med 357:83-4; author reply 85. 2007
  94. ncbi request reprint ROC-type assessments of medical imaging and CAD technologies: a perspective
    David Gur
    Department of Radiology, University of Pittsburgh School of Medicine, 300 Halket St, Suite 4200, Pittsburgh, PA 15213 3180, USA
    Acad Radiol 10:402-3. 2003
  95. ncbi request reprint Prospective study of electrical impedance scanning for identifying young women at risk for breast cancer
    Alexander Stojadinovic
    Walter Reed Army Medical Center, Washington, DC 20307, USA
    Breast Cancer Res Treat 97:179-89. 2006
    ....
  96. ncbi request reprint Imaging technology and practice assessments: diagnostic performance, clinical relevance, and generalizability in a changing environment
    David Gur
    Radiology 233:309-12. 2004

Research Grants33

  1. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2009
    ..We will develop closed-form solutions for the ANOVA procedure conducted on all possible bootstrap values. ..
  2. The Laboratory Effect in Breast Cancer Detection Studies
    David Gur; Fiscal Year: 2007
    ..The comparison we are attempting to do is at the very core of our ability (or not) to generalize laboratory observer performance data to the general clinical environment in a valid manner. ..
  3. Assessment of Variance Structure in ROC Studies
    David Gur; Fiscal Year: 2005
    ..e., those that are the less demanding of the expensive resources of gathering patient cases and expanding radiologists reading time. ..
  4. The Laboratory Effect in Breast Cancer Detection Studies
    David Gur; Fiscal Year: 2005
    ..The comparison we are attempting to do is at the very core of our ability (or not) to generalize laboratory observer performance data to the general clinical environment in a valid manner. ..
  5. RULE-BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 2006
    ..We propose to do so twice during the project on a large number of biopsy-proven cases. ..
  6. Assessment of Variance Structure in ROC Studies
    David Gur; Fiscal Year: 2006
    ..e., those that are the less demanding of the expensive resources of gathering patient cases and expanding radiologists reading time. ..
  7. The Laboratory Effect in Breast Cancer Detection Studies
    David Gur; Fiscal Year: 2006
    ..The comparison we are attempting to do is at the very core of our ability (or not) to generalize laboratory observer performance data to the general clinical environment in a valid manner. ..
  8. Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
    David Gur; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  9. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2007
    ..We will develop closed-form solutions for the ANOVA procedure conducted on all possible bootstrap values. ..
  10. Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
    David Gur; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  11. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2008
    ..We will develop closed-form solutions for the ANOVA procedure conducted on all possible bootstrap values. ..
  12. Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
    David Gur; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  13. Digital Breast Tomosynthesis (DBT) in a Screening Environment: a Prospective Stud
    David Gur; Fiscal Year: 2010
    ....
  14. RULE-BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 2005
    ..We propose to do so twice during the project on a large number of biopsy-proven cases. ..
  15. Assessment of Variance Structure in ROC Studies
    David Gur; Fiscal Year: 2004
    ..e., those that are the less demanding of the expensive resources of gathering patient cases and expanding radiologists reading time. ..
  16. RULE BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 1999
    ..We will also assess a number of issues associated with system's performance when multiple images (e.g., views) and/or multiple independent schemes are available and are used to optimize the results of a diagnostic examination. ..
  17. PREVALENCE EFFECT IN IMAGING SYSTEMS EVALUATIONS
    David Gur; Fiscal Year: 1999
    ..abstract_text> ..
  18. RULE BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 2000
    ..We will also assess a number of issues associated with system's performance when multiple images (e.g., views) and/or multiple independent schemes are available and are used to optimize the results of a diagnostic examination. ..
  19. PREVALENCE EFFECT IN IMAGING SYSTEMS EVALUATIONS
    David Gur; Fiscal Year: 2000
    ..abstract_text> ..
  20. OBSERVER PERFORMANCE STUDIES-READER SELECTION & TRAINING
    David Gur; Fiscal Year: 2000
    ..While they proposed to continue to investigate several aspects in this regard, the current proposal would focus on the possible effects of observer (reader) selection and training on study design and results. ..
  21. OBSERVER PERFORMANCE STUDIES-READER SELECTION & TRAINING
    David Gur; Fiscal Year: 2001
    ..While they proposed to continue to investigate several aspects in this regard, the current proposal would focus on the possible effects of observer (reader) selection and training on study design and results. ..
  22. PREVALENCE EFFECT IN IMAGING SYSTEMS EVALUATIONS
    David Gur; Fiscal Year: 2001
    ..abstract_text> ..
  23. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2002
    ..abstract_text> ..
  24. OBSERVER PERFORMANCE STUDIES-READER SELECTION & TRAINING
    David Gur; Fiscal Year: 2002
    ..While they proposed to continue to investigate several aspects in this regard, the current proposal would focus on the possible effects of observer (reader) selection and training on study design and results. ..
  25. RULE-BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 2003
    ..We propose to do so twice during the project on a large number of biopsy-proven cases. ..
  26. RULE-BASED CAD OF DIGITIZED MAMMOGRAMS
    David Gur; Fiscal Year: 2004
    ..We propose to do so twice during the project on a large number of biopsy-proven cases. ..
  27. Digital Breast Tomosynthesis (DBT) in a Screening Environment: a Prospective Stud
    David Gur; Fiscal Year: 2011
    ....