P Gupta

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Structurally specific heparan sulfates support primitive human hematopoiesis by formation of a multimolecular stem cell niche
    P Gupta
    Departments of Medicine, Biochemistry, and Orthopaedic Surgery, VA Medical Center, University of Minnesota Medical School, Minneapolis, MN, USA
    Blood 92:4641-51. 1998
  2. ncbi Long-term blood product transfusion support for patients with myelodysplastic syndromes (MDS): cost analysis and complications
    P Gupta
    Hematology Oncology Section 111E, Veterans Administration Medical Center, Minneapolis, MN 55417, USA
    Leuk Res 23:953-9. 1999
  3. ncbi Human LTC-IC can be maintained for at least 5 weeks in vitro when interleukin-3 and a single chemokine are combined with O-sulfated heparan sulfates: requirement for optimal binding interactions of heparan sulfate with early-acting cytokines and matrix pr
    P Gupta
    Department of Medicine, Veterans Affairs Medical Center Minneapolis, MN 55417, USA
    Blood 95:147-55. 2000
  4. ncbi Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Biochim Biophys Acta 1453:63-73. 1999
  5. ncbi Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Angiogenesis 3:147-58. 1999
  6. ncbi VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, 55455, USA
    Exp Cell Res 247:495-504. 1999
  7. ncbi Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2
    Z-Z Su
    Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 25:2339-48. 2006

Collaborators

Detail Information

Publications7

  1. ncbi Structurally specific heparan sulfates support primitive human hematopoiesis by formation of a multimolecular stem cell niche
    P Gupta
    Departments of Medicine, Biochemistry, and Orthopaedic Surgery, VA Medical Center, University of Minnesota Medical School, Minneapolis, MN, USA
    Blood 92:4641-51. 1998
    ..These findings may have important implications for ex vivo expansion of and gene transfer into primitive hematopoietic progenitors...
  2. ncbi Long-term blood product transfusion support for patients with myelodysplastic syndromes (MDS): cost analysis and complications
    P Gupta
    Hematology Oncology Section 111E, Veterans Administration Medical Center, Minneapolis, MN 55417, USA
    Leuk Res 23:953-9. 1999
    ....
  3. ncbi Human LTC-IC can be maintained for at least 5 weeks in vitro when interleukin-3 and a single chemokine are combined with O-sulfated heparan sulfates: requirement for optimal binding interactions of heparan sulfate with early-acting cytokines and matrix pr
    P Gupta
    Department of Medicine, Veterans Affairs Medical Center Minneapolis, MN 55417, USA
    Blood 95:147-55. 2000
    ..Blood. 2000;95:147-155)..
  4. ncbi Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Biochim Biophys Acta 1453:63-73. 1999
    ..These data imply that cell surface HS-mediated mechanisms play a key role in TSP-mediated sickle erythrocyte adhesion to endothelium, and heparin may be of use for inhibition of this adhesion...
  5. ncbi Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Angiogenesis 3:147-58. 1999
    ....
  6. ncbi VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
    K Gupta
    Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, 55455, USA
    Exp Cell Res 247:495-504. 1999
    ..Activation of the MAPK pathway together with inhibition of SAPK/JNK activity by VEGF appears to be a key event in determining whether an endothelial cell survives or undergoes programmed cell death...
  7. ncbi Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2
    Z-Z Su
    Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 25:2339-48. 2006
    ....