Naveen Gupta

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    Naveen Gupta
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 179:1855-63. 2007
  2. pmc Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
    Anna Krasnodembskaya
    Cardiovascular Research Institute and Department of Anesthesiology, University of California San Francisco, 505 Parnassus Ave, CA 94143, USA
    Am J Physiol Lung Cell Mol Physiol 302:L1003-13. 2012
  3. pmc Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37
    Anna Krasnodembskaya
    The Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Stem Cells 28:2229-38. 2010
  4. pmc Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury
    Xiao Su
    Cardiovascular Research Institute, University of California, San Francisco, California 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 297:L1-5. 2009
  5. pmc Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
    Jae W Lee
    Department of Anesthesiology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 106:16357-62. 2009
  6. pmc Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats
    Xiao Su
    Cardiovascular Research Institute, University of California San Francisco, HSW 825, 505 Parnassus Ave, San Francisco, CA 94143 0130, USA
    Am J Respir Cell Mol Biol 37:186-92. 2007
  7. pmc Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury
    Joyce S Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California 94143, USA
    Anat Rec (Hoboken) 294:165-72. 2011
  8. pmc Potential application of mesenchymal stem cells in acute lung injury
    Jae Woo Lee
    University of California, Anesthesiology, 505 Parnassus Avenue, Box 0648, San Francisco, CA 94143 0648, USA
    Expert Opin Biol Ther 9:1259-70. 2009
  9. ncbi request reprint Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice
    Vladimir B Serikov
    Children s Hospital Oakland Research Institute, Oakland, California 94609, USA
    Anat Rec (Hoboken) 290:1033-45. 2007
  10. ncbi request reprint Lung epithelial cells induce endodermal differentiation in mouse mesenchymal bone marrow stem cells by paracrine mechanism
    Boris V Popov
    Children s Hospital Oakland Research Institute, Oakland, CA, USA
    Tissue Eng 13:2441-50. 2007

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    Naveen Gupta
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 179:1855-63. 2007
    ..In conclusion, treatment with intrapulmonary MSC markedly decreases the severity of endotoxin-induced acute lung injury and improves survival in mice...
  2. pmc Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
    Anna Krasnodembskaya
    Cardiovascular Research Institute and Department of Anesthesiology, University of California San Francisco, 505 Parnassus Ave, CA 94143, USA
    Am J Physiol Lung Cell Mol Physiol 302:L1003-13. 2012
    ..Thus intravenous MSC increased survival from gram-negative peritoneal sepsis, in part by a monocyte-dependent increase in bacterial phagocytosis...
  3. pmc Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37
    Anna Krasnodembskaya
    The Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Stem Cells 28:2229-38. 2010
    ..Human bone marrow-derived MSCs possess direct antimicrobial activity, which is mediated in part by the secretion of human cathelicidin hCAP-18/ LL-37...
  4. pmc Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury
    Xiao Su
    Cardiovascular Research Institute, University of California, San Francisco, California 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 297:L1-5. 2009
    ..In summary, BAL RAGE is an indicator of ALI, and it may be useful in distinguishing direct from indirect models of ALI as well as assessing the response to specific therapies...
  5. pmc Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
    Jae W Lee
    Department of Anesthesiology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 106:16357-62. 2009
    ..In summary, treatment with allogeneic human MSCs or the conditioned medium restores normal fluid balance in an ex vivo perfused human lung injured by E. coli endotoxin...
  6. pmc Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats
    Xiao Su
    Cardiovascular Research Institute, University of California San Francisco, HSW 825, 505 Parnassus Ave, San Francisco, CA 94143 0130, USA
    Am J Respir Cell Mol Biol 37:186-92. 2007
    ..These results indicate that activation of alpha7 nAChR may provide a new therapeutic pathway for the treatment of acute lung injury...
  7. pmc Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury
    Joyce S Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California 94143, USA
    Anat Rec (Hoboken) 294:165-72. 2011
    ..This model should be useful to investigators studying ALI who want to simulate the clinical setting in which more than one insult often leads to greater clinical lung injury...
  8. pmc Potential application of mesenchymal stem cells in acute lung injury
    Jae Woo Lee
    University of California, Anesthesiology, 505 Parnassus Avenue, Box 0648, San Francisco, CA 94143 0648, USA
    Expert Opin Biol Ther 9:1259-70. 2009
    ..The review concludes with a discussion of future research directions required for potential clinical trials...
  9. ncbi request reprint Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice
    Vladimir B Serikov
    Children s Hospital Oakland Research Institute, Oakland, California 94609, USA
    Anat Rec (Hoboken) 290:1033-45. 2007
    ..These data confirm that bone marrow-derived cultured mesenchymal cells can participate in the recovery of the injured airway epithelium after naphthalene-induced injury with minimal long-term engraftment...
  10. ncbi request reprint Lung epithelial cells induce endodermal differentiation in mouse mesenchymal bone marrow stem cells by paracrine mechanism
    Boris V Popov
    Children s Hospital Oakland Research Institute, Oakland, CA, USA
    Tissue Eng 13:2441-50. 2007
    ..We conclude that A-549 cells can trigger epithelial differentiation of MSCs by a paracrine mechanism that may include activation of beta-catenin signaling...
  11. ncbi request reprint Sepsis and stretch: synergistic effects on alveolar epithelial cell death?
    Naveen Gupta
    Crit Care Med 34:1846-7. 2006