Zhi Ling Guo

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Nucleus ambiguus cholinergic neurons activated by acupuncture: relation to enkephalin
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Brain Res 1442:25-35. 2012
  2. ncbi request reprint Role of cAMP in activation of ischemically sensitive abdominal visceral afferents
    Z L Guo
    Department of Medicine, University of California, Irvine, California 92697, USA
    Am J Physiol Heart Circ Physiol 278:H843-52. 2000
  3. pmc Activation of reciprocal pathways between arcuate nucleus and ventrolateral periaqueductal gray during electroacupuncture: involvement of VGLUT3
    Zhi Ling Guo
    Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Brain Res 1360:77-88. 2010
  4. pmc Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: role of synthase isoforms
    Zhi Ling Guo
    Department of Medicine, School of Medicine, University of California, Susan Samueli Center for Integrative Medicine, Irvine, Irvine, California 92697 4075, USA
    Am J Physiol Heart Circ Physiol 297:H1478-86. 2009
  5. pmc Responses of opioid and serotonin containing medullary raphe neurons to electroacupuncture
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1229:125-36. 2008
  6. pmc Expression of c-Fos in arcuate nucleus induced by electroacupuncture: relations to neurons containing opioids and glutamate
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1166:65-76. 2007
  7. ncbi request reprint Responses of neurons containing VGLUT3/nNOS-cGMP in the rVLM to cardiac stimulation
    Zhi Ling Guo
    Department of Medicine, University of California, Irvine, Irvine, California 92697 4075, USA
    Neuroreport 17:255-9. 2006
  8. ncbi request reprint Stimulation of cardiac sympathetic afferents activates glutamatergic neurons in the parabrachial nucleus: relation to neurons containing nNOS
    Zhi Ling Guo
    Department of Medicine, C240 Medical Science 1, University of California, Irvine, Irvine, CA 92697 4075, USA
    Brain Res 1053:97-107. 2005
  9. ncbi request reprint Medullary pathways involved in cardiac sympathoexcitatory reflexes in the cat
    Zhi Ling Guo
    Department of Medicine, C240D Medical Science I, University of California at Irvine, Irvine, CA 92697 4075, USA
    Brain Res 925:55-66. 2002
  10. ncbi request reprint Central pathways in the pons and midbrain involved in cardiac sympathoexcitatory reflexes in cats
    Z L Guo
    Department of Medicine, C240D Medical Science I, University of California, Irvine, Irvine, CA 92697 4075, USA
    Neuroscience 113:435-47. 2002

Detail Information

Publications24

  1. pmc Nucleus ambiguus cholinergic neurons activated by acupuncture: relation to enkephalin
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Brain Res 1442:25-35. 2012
    ..These results suggest that EA at the P5-P6 acupoints has the potential to influence parasympathetic outflow and cardiovascular function, likely through an enkephalinergic mechanism...
  2. ncbi request reprint Role of cAMP in activation of ischemically sensitive abdominal visceral afferents
    Z L Guo
    Department of Medicine, University of California, Irvine, California 92697, USA
    Am J Physiol Heart Circ Physiol 278:H843-52. 2000
    ..These data suggest that cAMP contributes to the activation of abdominal visceral afferents during ischemia, particularly to the action of PGs on activation and/or sensitization of these endings...
  3. pmc Activation of reciprocal pathways between arcuate nucleus and ventrolateral periaqueductal gray during electroacupuncture: involvement of VGLUT3
    Zhi Ling Guo
    Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Brain Res 1360:77-88. 2010
    ....
  4. pmc Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: role of synthase isoforms
    Zhi Ling Guo
    Department of Medicine, School of Medicine, University of California, Susan Samueli Center for Integrative Medicine, Irvine, Irvine, California 92697 4075, USA
    Am J Physiol Heart Circ Physiol 297:H1478-86. 2009
    ..These data suggest that NO, specifically nNOS, mediates sympathetic cardiac-cardiovascular responses through its action in the rVLM...
  5. pmc Responses of opioid and serotonin containing medullary raphe neurons to electroacupuncture
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1229:125-36. 2008
    ..These results suggest that the medullary raphe nuclei, particularly the NRP, process somatic signals during EA and participate in EA-related modulation of cardiovascular function through an opioid or serotonergic mechanism...
  6. pmc Expression of c-Fos in arcuate nucleus induced by electroacupuncture: relations to neurons containing opioids and glutamate
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1166:65-76. 2007
    ..The results imply that EA at P5-P6 has the potential to influence ARC neurons containing multiple neuronal substances that subsequently modulate cardiovascular function...
  7. ncbi request reprint Responses of neurons containing VGLUT3/nNOS-cGMP in the rVLM to cardiac stimulation
    Zhi Ling Guo
    Department of Medicine, University of California, Irvine, Irvine, California 92697 4075, USA
    Neuroreport 17:255-9. 2006
    ..Findings indicate activation of rostral ventrolateral medulla glutamatergic neurons by cardiac stimulation, which may be influenced by nitric oxide via cGMP...
  8. ncbi request reprint Stimulation of cardiac sympathetic afferents activates glutamatergic neurons in the parabrachial nucleus: relation to neurons containing nNOS
    Zhi Ling Guo
    Department of Medicine, C240 Medical Science 1, University of California, Irvine, Irvine, CA 92697 4075, USA
    Brain Res 1053:97-107. 2005
    ..Nitric oxide has the potential to influence the action of glutamatergic neurons in regulation of excitatory cardiovascular responses induced by activation of cardiac sympathetic afferents...
  9. ncbi request reprint Medullary pathways involved in cardiac sympathoexcitatory reflexes in the cat
    Zhi Ling Guo
    Department of Medicine, C240D Medical Science I, University of California at Irvine, Irvine, CA 92697 4075, USA
    Brain Res 925:55-66. 2002
    ..These findings indicate that the activated neurons in the medulla, especially in the VLM, are involved in integration of cardiac-cardiovascular sympathoexcitatory reflexes...
  10. ncbi request reprint Central pathways in the pons and midbrain involved in cardiac sympathoexcitatory reflexes in cats
    Z L Guo
    Department of Medicine, C240D Medical Science I, University of California, Irvine, Irvine, CA 92697 4075, USA
    Neuroscience 113:435-47. 2002
    ..From these results we suggest that cardiovascular-related regions in the pons and midbrain form part of a long loop in central integration of cardiac sympathoexcitatory reflexes...
  11. ncbi request reprint Electroacupuncture induces c-Fos expression in the rostral ventrolateral medulla and periaqueductal gray in cats: relation to opioid containing neurons
    Zhi Ling Guo
    Department of Medicine, C240 Medical Science 1, University of California, Irvine, CA 92697 4075, USA
    Brain Res 1030:103-15. 2004
    ..These neurons likely form the substrate for EA's influence on sympathoexcitatory cardiovascular reflexes...
  12. ncbi request reprint Involvement of nuclei in the hypothalamus in cardiac sympathoexcitatory reflexes in cats
    Zhi Ling Guo
    Department of Medicine, C240 Medical Science 1, University of California, Irvine, Irvine, CA 92697 4075, USA
    Brain Res 1006:36-48. 2004
    ..Nitric oxide (NO) may function as a neurotransmitter or as a neuromodulator in the PVN during these cardiac-cardiovascular responses...
  13. ncbi request reprint Activation of nitric oxide-producing neurons in the brain stem during cardiac sympathoexcitatory reflexes in the cat
    Z L Guo
    Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Neuroscience 116:167-78. 2003
    ..Our data suggest that nitric oxide functions as a neurotransmitter/modulator in these areas to regulate the cardiac sympathoexcitatory reflexes...
  14. pmc Serotonergic projection from nucleus raphe pallidus to rostral ventrolateral medulla modulates cardiovascular reflex responses during acupuncture
    Ali Moazzami
    Susan Samueli Center for Integrative Medicine, Department of Medicine, Medical Science 1 C240, School of Medicine, University of California, Irvine, CA 92697 4075, USA
    J Appl Physiol (1985) 108:1336-46. 2010
    ..Thus activation of the NRP, through a mechanism involving serotonergic neurons and 5-HT1A receptors in the rVLM during somatic stimulation with EA, attenuates sympathoexcitatory cardiovascular reflexes...
  15. pmc Long-loop pathways in cardiovascular electroacupuncture responses
    Peng Li
    Department of Medicine, University of California, Irvine, CA, USA
    J Appl Physiol (1985) 106:620-30. 2009
    ..Direct projections from the ARC to the rVLM, which serve as an important source of beta-endorphin, appear also to exist...
  16. pmc Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexes
    Liang Wu Fu
    Department of Medicine, College of Medicine, University of California, Irvine, 92697, USA
    Am J Physiol Heart Circ Physiol 302:H1444-53. 2012
    ..These data are the first to show that NMDA and AMPA ionotropic glutamate receptors in the elPBN play an important role in processing cardiac excitatory reflex responses...
  17. pmc Electroacupuncture modulation of reflex hypertension in rats: role of cholecystokinin octapeptide
    Min Li
    Department of Medicine and Susan Samueli Center of Integrative Medicine, University of California, Irvine, California
    Am J Physiol Regul Integr Comp Physiol 305:R404-13. 2013
    ....
  18. ncbi request reprint Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats
    Wei Zhou
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, USA
    Am J Physiol Heart Circ Physiol 291:H1309-18. 2006
    ..These results suggest that glutamate in the rVLM serves as an excitatory neurotransmitter through a baroreflex-independent mechanism and that both NMDA and AMPA receptors mediate the visceral sympathoexcitatory reflex responses...
  19. pmc Medullary GABAergic mechanisms contribute to electroacupuncture modulation of cardiovascular depressor responses during gastric distention in rats
    Stephanie C Tjen-A-Looi
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Am J Physiol Regul Integr Comp Physiol 304:R321-32. 2013
    ..Thus, EA through GABAA receptor mechanisms in the rVLM, cVLM, and NAmb modulates gastric distention-induced reflex sympathoinhibition and vagal excitation...
  20. pmc Repetitive electroacupuncture causes prolonged increased met-enkephalin expression in the rVLM of conscious rats
    Min Li
    Department of Medicine, School of Medicine, University of California, Irvine, 92697 4075, United States
    Auton Neurosci 170:30-5. 2012
    ..Since opioids in the rVLM contribute importantly to the action of EA on sympathetic outflow, this mechanism may contribute to the prolonged action of acupuncture on elevated blood pressure in patients...
  21. pmc An arcuate-ventrolateral periaqueductal gray reciprocal circuit participates in electroacupuncture cardiovascular inhibition
    Peng Li
    Department of Medicine, Susan Samueli Center for Integrative Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, United States
    Auton Neurosci 158:13-23. 2010
    ..Thus, a reciprocal excitatory glutamatergic neural circuit between the arcuate and vlPAG contributes to long-lasting EA cardiovascular inhibition. ACh in the arcuate but not in the vlPAG participates in the reciprocal excitation...
  22. ncbi request reprint Role of glutamate in the rostral ventrolateral medulla in acupuncture-related modulation of visceral reflex sympathoexcitation
    Wei Zhou
    Department of Medicine and Susan Samueli Center for Integrative Medicine, College of Medicine, University of California, Irvine, California 92697 4075, USA
    Am J Physiol Heart Circ Physiol 292:H1868-75. 2007
    ..These data suggest that EA attenuates BK-induced visceral sympathoexcitatory reflexes through opioid-mediated inhibition of Glu's action in the rVLM...
  23. pmc Endogenous endothelin stimulates cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    J Physiol 588:2473-86. 2010
    ....
  24. pmc Undiscovered role of endogenous thromboxane A2 in activation of cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    J Physiol 586:3287-300. 2008
    ....