Research Topics
Species | Zhi Ling GuoSummaryAffiliation: University of California Country: USA Publications
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Publications
Nucleus ambiguus cholinergic neurons activated by acupuncture: relation to enkephalinZhi Ling Guo
Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Brain Res 1442:25-35. 2012..These results suggest that EA at the P5-P6 acupoints has the potential to influence parasympathetic outflow and cardiovascular function, likely through an enkephalinergic mechanism...
Role of cAMP in activation of ischemically sensitive abdominal visceral afferentsZ L Guo
Department of Medicine, University of California, Irvine, California 92697, USA
Am J Physiol Heart Circ Physiol 278:H843-52. 2000..These data suggest that cAMP contributes to the activation of abdominal visceral afferents during ischemia, particularly to the action of PGs on activation and/or sensitization of these endings...
Activation of reciprocal pathways between arcuate nucleus and ventrolateral periaqueductal gray during electroacupuncture: involvement of VGLUT3Zhi Ling Guo
Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Brain Res 1360:77-88. 2010....
Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: role of synthase isoformsZhi Ling Guo
Department of Medicine, School of Medicine, University of California, Susan Samueli Center for Integrative Medicine, Irvine, Irvine, California 92697 4075, USA
Am J Physiol Heart Circ Physiol 297:H1478-86. 2009..These data suggest that NO, specifically nNOS, mediates sympathetic cardiac-cardiovascular responses through its action in the rVLM...
Responses of opioid and serotonin containing medullary raphe neurons to electroacupunctureZhi Ling Guo
Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
Brain Res 1229:125-36. 2008..These results suggest that the medullary raphe nuclei, particularly the NRP, process somatic signals during EA and participate in EA-related modulation of cardiovascular function through an opioid or serotonergic mechanism...
Expression of c-Fos in arcuate nucleus induced by electroacupuncture: relations to neurons containing opioids and glutamateZhi Ling Guo
Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
Brain Res 1166:65-76. 2007..The results imply that EA at P5-P6 has the potential to influence ARC neurons containing multiple neuronal substances that subsequently modulate cardiovascular function...
Responses of neurons containing VGLUT3/nNOS-cGMP in the rVLM to cardiac stimulationZhi Ling Guo
Department of Medicine, University of California, Irvine, Irvine, California 92697 4075, USA
Neuroreport 17:255-9. 2006..Findings indicate activation of rostral ventrolateral medulla glutamatergic neurons by cardiac stimulation, which may be influenced by nitric oxide via cGMP...
Stimulation of cardiac sympathetic afferents activates glutamatergic neurons in the parabrachial nucleus: relation to neurons containing nNOSZhi Ling Guo
Department of Medicine, C240 Medical Science 1, University of California, Irvine, Irvine, CA 92697 4075, USA
Brain Res 1053:97-107. 2005..Nitric oxide has the potential to influence the action of glutamatergic neurons in regulation of excitatory cardiovascular responses induced by activation of cardiac sympathetic afferents...
Medullary pathways involved in cardiac sympathoexcitatory reflexes in the catZhi Ling Guo
Department of Medicine, C240D Medical Science I, University of California at Irvine, Irvine, CA 92697 4075, USA
Brain Res 925:55-66. 2002..These findings indicate that the activated neurons in the medulla, especially in the VLM, are involved in integration of cardiac-cardiovascular sympathoexcitatory reflexes...
Electroacupuncture induces c-Fos expression in the rostral ventrolateral medulla and periaqueductal gray in cats: relation to opioid containing neuronsZhi Ling Guo
Department of Medicine, C240 Medical Science 1, University of California, Irvine, CA 92697 4075, USA
Brain Res 1030:103-15. 2004..These neurons likely form the substrate for EA's influence on sympathoexcitatory cardiovascular reflexes...
Involvement of nuclei in the hypothalamus in cardiac sympathoexcitatory reflexes in catsZhi Ling Guo
Department of Medicine, C240 Medical Science 1, University of California, Irvine, Irvine, CA 92697 4075, USA
Brain Res 1006:36-48. 2004..Nitric oxide (NO) may function as a neurotransmitter or as a neuromodulator in the PVN during these cardiac-cardiovascular responses...
Activation of nitric oxide-producing neurons in the brain stem during cardiac sympathoexcitatory reflexes in the catZ L Guo
Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Neuroscience 116:167-78. 2003..Our data suggest that nitric oxide functions as a neurotransmitter/modulator in these areas to regulate the cardiac sympathoexcitatory reflexes...
Central pathways in the pons and midbrain involved in cardiac sympathoexcitatory reflexes in catsZ L Guo
Department of Medicine, C240D Medical Science I, University of California, Irvine, Irvine, CA 92697 4075, USA
Neuroscience 113:435-47. 2002..From these results we suggest that cardiovascular-related regions in the pons and midbrain form part of a long loop in central integration of cardiac sympathoexcitatory reflexes...
Serotonergic projection from nucleus raphe pallidus to rostral ventrolateral medulla modulates cardiovascular reflex responses during acupunctureAli Moazzami
Susan Samueli Center for Integrative Medicine, Department of Medicine, Medical Science 1 C240, School of Medicine, University of California, Irvine, CA 92697 4075, USA
J Appl Physiol 108:1336-46. 2010..Thus activation of the NRP, through a mechanism involving serotonergic neurons and 5-HT1A receptors in the rVLM during somatic stimulation with EA, attenuates sympathoexcitatory cardiovascular reflexes...
Long-loop pathways in cardiovascular electroacupuncture responsesPeng Li
Department of Medicine, University of California, Irvine, CA, USA
J Appl Physiol 106:620-30. 2009..Direct projections from the ARC to the rVLM, which serve as an important source of beta-endorphin, appear also to exist...
Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of catsWei Zhou
Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, USA
Am J Physiol Heart Circ Physiol 291:H1309-18. 2006..These results suggest that glutamate in the rVLM serves as an excitatory neurotransmitter through a baroreflex-independent mechanism and that both NMDA and AMPA receptors mediate the visceral sympathoexcitatory reflex responses...
Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexesLiang Wu Fu
Department of Medicine, College of Medicine, University of California, Irvine, 92697, USA
Am J Physiol Heart Circ Physiol 302:H1444-53. 2012..These data are the first to show that NMDA and AMPA ionotropic glutamate receptors in the elPBN play an important role in processing cardiac excitatory reflex responses...
Role of glutamate in the rostral ventrolateral medulla in acupuncture-related modulation of visceral reflex sympathoexcitationWei Zhou
Department of Medicine and Susan Samueli Center for Integrative Medicine, College of Medicine, University of California, Irvine, California 92697 4075, USA
Am J Physiol Heart Circ Physiol 292:H1868-75. 2007..These data suggest that EA attenuates BK-induced visceral sympathoexcitatory reflexes through opioid-mediated inhibition of Glu's action in the rVLM...
An arcuate-ventrolateral periaqueductal gray reciprocal circuit participates in electroacupuncture cardiovascular inhibitionPeng Li
Department of Medicine, Susan Samueli Center for Integrative Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, United States
Auton Neurosci 158:13-23. 2010..Thus, a reciprocal excitatory glutamatergic neural circuit between the arcuate and vlPAG contributes to long-lasting EA cardiovascular inhibition. ACh in the arcuate but not in the vlPAG participates in the reciprocal excitation...
Endogenous endothelin stimulates cardiac sympathetic afferents during ischaemiaLiang Wu Fu
Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
J Physiol 588:2473-86. 2010....
Undiscovered role of endogenous thromboxane A2 in activation of cardiac sympathetic afferents during ischaemiaLiang Wu Fu
Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
J Physiol 586:3287-300. 2008....
Repetitive electroacupuncture causes prolonged increased met-enkephalin expression in the rVLM of conscious ratsMin Li
Department of Medicine, School of Medicine, University of California, Irvine, 92697 4075, United States
Auton Neurosci 170:30-5. 2012..Since opioids in the rVLM contribute importantly to the action of EA on sympathetic outflow, this mechanism may contribute to the prolonged action of acupuncture on elevated blood pressure in patients...
